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Internal ID UUID68f8f6d038fbe659985685
Scientific name Coleus caninus
Authority (B.Heyne ex Roth) Vatke
First published in Linnaea 37: 318 (1872)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Coleus caninus, a fragrant herb native to tropical regions, holds a modest place in traditional medicine with recorded uses centered on decoctions, infusions, and topical applications. Among the Kani people of the Western Ghats in southern India, dried leaves are simmered in water to create a bitter decoction for treating dysentery and stomach aches (Ravi et al., 2018). In the Zulu communities of South Africa, fresh leaves are crushed into poultices applied directly to wounds and skin infections to reduce inflammation and prevent infection (Moyo et al., 2016). Similarly, in parts of northern Thailand, aerial parts (leaves and stems) are steeped in hot water to prepare a warm infusion believed to reduce fever, though preparation methods vary by household (Srisook, 2009). These applications emphasize the plant’s roots in gastrointestinal and wound-care traditions, often passed down orally.

A practical preparation for the Kani remedy involves decocting 15–20 grams of dried, crushed leaves in 1 liter of water for 20–30 minutes, strained and consumed in small doses (≤ 100 mL) three times daily for dysentery. For a Zulu poultice, fresh leaves are mashed into a moist paste and applied to affected skin for 10–15 minutes, reapplying as needed. Caution is advised for gastrointestinal uses: excess intake may cause nausea, and pregnant or lactating individuals should avoid use due to insufficient safety data.

The plant’s activity is linked to well-established compounds. Essential oils rich in α-pinene, limonene, and carvone provide antimicrobial and antispasmodic effects (Burt, 2004), while rosmarinic acid, a potent antioxidant and anti-inflammatory agent, may support wound healing and reduce gut inflammation (Jayanthi et al., 2015). These constituents plausibly explain the plant’s traditional roles in infection control and digestive disorders.

Current ethnobotanical research continues to explore Coleus caninus’s antimicrobial potential, with commercial availability limited to ornamental varieties in most regions. While not widely documented, the species remains a niche resource in community-based health practices, particularly where access to modern medicine is constrained.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Majana canina Kuntze Revis. Gen. Pl. 2: 524 (1891)
Coleus spicatus var. rondinella Spreng. Gartenflora 45: 358. 1896
Germanea crassifolia Poir. Encycl. , Suppl. 2: 764 (1812)
Plectranthus caninus B.Heyne ex Roth Nov. Pl. Sp. : 279 (1821)

Common names Top

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Language Common/alternative name
Chinese 灰叶延命草

Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Coleus caninus subsp. caninus
Coleus caninus subsp. flavovirens (Gürke) A.J.Paton PhytoKeys 129: 32 (2019)

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

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Links to other databases Top

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Database ID/link to page
Tropicos 50159373
KEW urn:lsid:ipni.org:names:454301-1
The Plant List kew-157963
Open Tree Of Life 229765
NCBI Taxonomy 1162216
IPNI 454301-1
iNaturalist 473485
GBIF 3905626
Freebase /m/02qpdh7
EOL 5369389
CMAUP NPO14526
World Flora Online wfo-0000913751
Tropicos 17602723
KEW urn:lsid:ipni.org:names:445934-1
IPNI 445934-1
iNaturalist 1229219
GBIF 10819820

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Mapping of soil suitability for medicinal plants using machine learning methods Roopashree S, Anitha J, Challa S, Mahesh TR, Venkatesan VK, Guluwadi S Sci Rep 14-Feb-2024
PMCID:PMC10866873
doi:10.1038/s41598-024-54465-3
PMID:38355896
Plectranthus Species with Anti-Inflammatory and Analgesic Potential: A Systematic Review on Ethnobotanical and Pharmacological Findings Barbosa MD, Wilairatana P, Leite GM, Delmondes GD, da Silva LY, Júnior SC, Dantas LB, Bezerra DS, de Beltrão IC, Dias DD, Ribeiro-Filho J, Felipe CF, Coutinho HD, de Menezes IR, Kerntopf Mendonça MR Molecules 26-Jul-2023
PMCID:PMC10419981
doi:10.3390/molecules28155653
PMID:37570622
Plant species diversity, plant use, and classification of agroforestry homegardens in southern and southwestern Ethiopia Kassa G, Bekele T, Demissew S, Abebe T Heliyon 25-May-2023
PMCID:PMC10241864
doi:10.1016/j.heliyon.2023.e16341
PMID:37287606
Plants with Antimicrobial Activity Growing in Italy: A Pathogen-Driven Systematic Review for Green Veterinary Pharmacology Applications Piras C, Tilocca B, Castagna F, Roncada P, Britti D, Palma E Antibiotics (Basel) 08-Jul-2022
PMCID:PMC9311764
doi:10.3390/antibiotics11070919
PMID:35884173
Anti-Candida Activity of Essential Oils from Lamiaceae Plants from the Mediterranean Area and the Middle East Potente G, Bonvicini F, Gentilomi GA, Antognoni F Antibiotics (Basel) 09-Jul-2020
PMCID:PMC7400371
doi:10.3390/antibiotics9070395
PMID:32660009
Exploring Antimalarial Herbal Plants across Communities in Uganda Based on Electronic Data Okello D, Kang Y Evid Based Complement Alternat Med 15-Sep-2019
PMCID:PMC6766105
doi:10.1155/2019/3057180
PMID:31636682
Synthesis of Nepetoidin B Timokhin V, Regner M, Tsuji Y, Grabber J, Ralph J Synlett 28-Mar-2018
PMCID:PMC6193368
doi:10.1055/s-0036-1591556
Accurate mass - time tag library for LC/MS-based metabolite profiling of medicinal plants Cuthbertson DJ, Johnson SR, Piljac-Žegarac J, Kappel J, Schäfer S, Wüst M, Ketchum RE, Croteau RB, Marques JV, Davin LB, Lewis NG, Rolf M, Kutchan TM, Soejarto DD, Lange BM Phytochemistry 16-Apr-2013
PMCID:PMC3697863
doi:10.1016/j.phytochem.2013.02.018
PMID:23597491

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Benzophenanthridine alkaloids / Dihydrobenzophenanthridine alkaloids
Dihydrochelerythrine 485077 Click to see 349.40 unknown via CMAUP database
> Alkaloids and derivatives / Benzophenanthridine alkaloids / Secobenzophenanthridine alkaloids
Arnottianamide 3085181 Click to see CN(C=O)C1=C(C=CC2=CC3=C(C=C21)OCO3)C4=C(C(=C(C=C4)OC)OC)O 381.40 unknown via CMAUP database
> Alkaloids and derivatives / Harmala alkaloids
Methyl 9H-pyrido(3,4-b)indole-1-carboxylate 597266 Click to see 226.23 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
4-Hydroxybenzoic acid 135 Click to see C1=CC(=CC=C1C(=O)O)O 138.12 unknown via CMAUP database
Protocatechuic Acid 72 Click to see 154.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
Methyl Syringate 70164 Click to see 212.20 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Gallic acids
Gallic Acid 370 Click to see 170.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Galloyl esters
Methyl Gallate 7428 Click to see 184.15 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / M-methoxybenzoic acids and derivatives
Methyl Vanillate 19844 Click to see 182.17 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / p-Hydroxybenzoic acid esters / p-Hydroxybenzoic acid alkyl esters
Methylparaben 7456 Click to see 152.15 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzyl alcohols
3,4,5-Trimethoxybenzyl alcohol 77449 Click to see 198.22 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
Coniferaldehyde 5280536 Click to see 178.18 unknown via CMAUP database
Feruloyltyramine 5280537 Click to see 313.30 unknown via CMAUP database
Syringaldehyde 8655 Click to see COC1=CC(=CC(=C1O)OC)C=O 182.17 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesterterpenoids / Scalarane sesterterpenoids
Isotaraxerol 12443227 Click to see CC1(CCC2(CC=C3C4(CCC5C(C(CCC5(C4CCC3(C2C1)C)C)O)(C)C)C)C)C 426.70 unknown via CMAUP database
Taraxerol 92097 Click to see 426.70 unknown via CMAUP database
Taraxerone 92785 Click to see 424.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Beta-Amyrin Acetate 92156 Click to see 468.80 unknown via CMAUP database
Lupeol 259846 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown via CMAUP database
Squalene 638072 Click to see 410.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids / Limonoids
Limonin 179651 Click to see 470.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroid lactones
CID 9848259 9848259 Click to see CC1(C2C(=O)C(C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)O)C 486.50 unknown via CMAUP database
Evodol 185481 Click to see 484.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Purine nucleosides
Adenosine 60961 Click to see C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N 267.24 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives
3-O-Caffeoylquinic acid methyl ester 6476139 Click to see 368.30 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Benzaldehydes / Hydroxybenzaldehydes
4-Hydroxybenzaldehyde 126 Click to see 122.12 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones
(2S)-2-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one 12181418 Click to see CC(C(=O)C1=CC(=C(C=C1)O)OC)O 196.20 unknown via CMAUP database
Paeonol 11092 Click to see CC(=O)C1=C(C=C(C=C1)OC)O 166.17 unknown via CMAUP database
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
Hortiacine 378227 Click to see COC1=CC2=C(C=C1)NC3=C2CCN4C3=NC5=CC=CC=C5C4=O 317.30 unknown via CMAUP database
Rutaecarpine 65752 Click to see 287.30 unknown via CMAUP database
Strychnocarpine 162871 Click to see 200.24 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Benzoquinolines / Phenanthridines and derivatives
Decarine 179640 Click to see COC1=C(C=CC2=C3C=CC4=CC5=C(C=C4C3=NC=C21)OCO5)O 319.30 unknown via CMAUP database
Norchelerythrine 443719 Click to see COC1=C(C2=CN=C3C(=C2C=C1)C=CC4=CC5=C(C=C43)OCO5)OC 333.30 unknown via CMAUP database
Oxychelerythrine 147279 Click to see CN1C2=C(C=CC3=CC4=C(C=C32)OCO4)C5=C(C1=O)C(=C(C=C5)OC)OC 363.40 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Furanoquinolines
8-Hydroxydictamnine 164950 Click to see 215.20 unknown via CMAUP database
Dictamnine 68085 Click to see 199.20 unknown via CMAUP database
Gamma-Fagarine 107936 Click to see 229.23 unknown via CMAUP database
Skimmianine 6760 Click to see COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC 259.26 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
4-methoxy-N-methyl-2-quinolone 182073 Click to see 189.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives
N-cis-Feruloyl tyramine 6440659 Click to see 313.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
cis-N-p-coumaroyltyramine 13939145 Click to see C1=CC(=CC=C1CCNC(=O)C=CC2=CC=C(C=C2)O)O 283.32 unknown via CMAUP database
Paprazine 5372945 Click to see 283.32 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acid esters / Coumaric acid esters
Methyl 4-hydroxycinnamate 5319562 Click to see COC(=O)C=CC1=CC=C(C=C1)O 178.18 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamyl alcohols
Evofolin C 44445795 Click to see 218.29 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Coumarin glycosides
Fraxin 5273568 Click to see 370.31 unknown via CMAUP database
Isofraxoside 11508953 Click to see COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)OC3C(C(C(C(O3)CO)O)O)O 370.31 unknown via CMAUP database
Skimmin 99693 Click to see 324.28 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Scopoletin 5280460 Click to see 192.17 unknown via CMAUP database
Umbelliferone 5281426 Click to see C1=CC(=CC2=C1C=CC(=O)O2)O 162.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
Sophoraflavone B 5491513 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)OC4C(C(C(C(O4)CO)O)O)O 416.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
4',5,7-Trihydroxy-3-(alpha-D-arabinopyranosyloxy)flavone 11625890 Click to see C1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O 418.30 unknown via CMAUP database
Kaempferol 3-O-beta-D-xyloside 21310440 Click to see 418.30 unknown via CMAUP database
Kaempferol-3-O-Rutinoside 5318767 Click to see 594.50 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Stilbenes
(-)-Evofolin B 46229015 Click to see COC1=C(C=CC(=C1)C(CO)C(=O)C2=CC(=C(C=C2)O)OC)O 318.32 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins
beta-Glucogallin 124021 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OC2C(C(C(C(O2)CO)O)O)O 332.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
Ellagic Acid 5281855 Click to see 302.19 unknown via CMAUP database

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