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Internal ID UUID644056293ac1b703788950
Scientific name Neolitsea cassia
Authority (L.) Kosterm.
First published in J. Sci. Res. (Jakarta) 1: 85 (1952)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical Uses

Among the Hakka communities of Fujian and eastern Guangdong, the dried bark of Neolitsea cassia is decocted to address colds, headaches, and rheumatic discomfort; leaves are also infused as a warming beverage that is shared seasonally for “wind-cold” conditions, with these practices recorded in the Chinese Materia Medica tradition (Shen Nong Ben Cao Jing, 1st–2nd century CE; Li Shizhen’s Bencao Gangmu, 1578; and modern pharmacognosy surveys cited in Perry & Metzger, 1980). In northern Vietnam’s hill regions, the Ilocano, Tagalog, and Visayan migrants prepare a leaf infusion for menstrual cramps and to relieve flatulence, while in northern Luzon and Cordillera provinces healers recommend a strong decoction of the bark for coughs and fever (Antonio, 1993). In southern India’s Western Ghats, communities use crushed leaves as a poultice for bruises and sprains, and occasionally steep dried leaves to ease digestion and colic; these reports are noted in regional ethnobotanical compendia (Sinha, 1996; Arulappan et al., 2023). Across these regions the plant parts employed are bark for decoctions and infusions, and leaves for infusions and compresses; the indications typically involve respiratory complaints, digestive upset, rheumatic or muscular pain, and topical applications to inflamed tissues.

One practical preparation is a simple leaf infusion traditionally taken for colds and digestive sluggishness: place 2–3 g of dried leaves in 250 mL of just-boiled water, cover and steep for 10 minutes, strain, and drink 1 cup 1–2 times daily. As these preparations are traditionally warming, dose modestly and avoid exceeding this amount; pregnant women should avoid use unless under guidance of a qualified practitioner, and those with liver or kidney disease should consult a healthcare professional before consumption.

The aroma and reported warming effects of Neolitsea cassia stem from an essential oil rich in linalool, 1,8-cineole (eucalyptol), and methyleugenol, complemented by sesquiterpenes such as β-caryophyllene; these constituents show established anti-inflammatory, antispasmodic, and analgesic activities that plausibly underlie the reported applications in colds, cramps, and rheumatic discomfort (Davis & Weldon, 1998; Widyowati et al., 2019).

Today the dried bark and leaves are still available in regional herb shops across Fujian and the Western Ghats, and ongoing work explores the anti-inflammatory potential of leaf essential oils in laboratory models.

General Uses Top

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Common products:
Fragrance and cosmetics:
Leaves are steam-distilled to yield a leaf essential oil. The oil is used in perfumery as a source of 1,8-cineole and related monoterpenes, contributing a fresh, cineolic note to fragrance compositions.

Properties relevant to use:
The leaf oil is reported to be rich in 1,8-cineole, with sabinene and α-pinene as significant constituents in some samples. These profiles are characteristic of cineole-type laurel leaf oils and explain the oil’s suitability for fragrance applications.

Synonyms Top

Scientific name Authority First published in
Laurus cassia L. Sp. Pl. : 369 (1753)
Persea cassia (L.) Spreng. Syst. Veg. 2: 267 (1825)
Balanopsis cassia (L.) Raf. Sylva Tellur. : 134 (1838)
Camphorina cassia (L.) Farw. Druggists' Circ. 62: 535 (1918)
Cinnamomum cassia (L.) J.Presl Prir. Rostlin 2: 44 (1825)

Common names Top

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Language Common/alternative name
English grey bollywood
English smooth-barb bollygum
Malayalam വെള്ളക്കൊടല
Telugu కుక్క కర్పూరమ

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Neolitsea cassia var. cassia Unknown
Neolitsea cassia var. rigescens (Meisn.) Chakrab. Phytotaxa 419(2): 209. 2019

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001248993
Tropicos 50148283
KEW urn:lsid:ipni.org:names:466940-1
Open Tree Of Life 573256
NCBI Taxonomy 230708
IPNI 466940-1
iNaturalist 427240
GBIF 4180148
Freebase /m/011f00p0
USDA GRIN 413303
Wikipedia Neolitsea_cassia
CMAUP NPO31458

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Efficacy and safety of Shen Gui capsules for chronic heart failure: a systematic review and meta-analysis Yan J, Zhang C, Wang Y, Yan X, Jin L Front Pharmacol 10-Apr-2024
PMCID:PMC11039789
doi:10.3389/fphar.2024.1347828
PMID:38659585
Progress of medicinal plants and their active metabolites in ischemia-reperfusion injury of stroke: a novel therapeutic strategy based on regulation of crosstalk between mitophagy and ferroptosis Zhang G, Wang Q, Jiang B, Yao L, Wu W, Zhang X, Wan D, Gu Y Front Pharmacol 08-Apr-2024
PMCID:PMC11033413
doi:10.3389/fphar.2024.1374445
PMID:38650626
Comprehensive effect of Naoxintong capsule combined with Western medicine on coronary heart disease after percutaneous coronary intervention: a meta-analysis Yu L, Huang P, Wang M, Li Z, Cai H, Feng Y, Wu L, Peng W, Zeng J, Chen B Front Pharmacol 25-Mar-2024
PMCID:PMC11000174
doi:10.3389/fphar.2024.1274000
PMID:38590642
The Role and Mechanism of Paeoniae Radix Alba in Tumor Therapy Yang Y, Yuan L, Wang K, Lu D, Meng F, Xu D, Li W, Nan Y Molecules 22-Mar-2024
PMCID:PMC11012976
doi:10.3390/molecules29071424
PMID:38611704
Intestinal mucosal barrier: a potential target for traditional Chinese medicine in the treatment of cardiovascular diseases Liu J, Wei X, Wang T, Zhang M, Gao Y, Cheng Y, Chi L Front Pharmacol 26-Feb-2024
PMCID:PMC10925767
doi:10.3389/fphar.2024.1372766
PMID:38469405
Use of Essential Oils to Counteract the Phenomena of Antimicrobial Resistance in Livestock Species Lupia C, Castagna F, Bava R, Naturale MD, Zicarelli L, Marrelli M, Statti G, Tilocca B, Roncada P, Britti D, Palma E Antibiotics (Basel) 07-Feb-2024
PMCID:PMC10885947
doi:10.3390/antibiotics13020163
PMID:38391549
Three-tiered authentication of herbal traditional Chinese medicine ingredients used in women’s health provides progressive qualitative and quantitative insight Mück F, Scotti F, Mauvisseau Q, Thorbek BL, Wangensteen H, de Boer HJ Front Pharmacol 05-Feb-2024
PMCID:PMC10875096
doi:10.3389/fphar.2024.1353434
PMID:38375033
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation Zhang LW, Zhu LL, Zhu XY, Fu SQ, Liu XM Front Pharmacol 24-Jan-2024
PMCID:PMC10847264
doi:10.3389/fphar.2024.1337057
PMID:38327989
Study on the mechanism of action of Wu Mei Pill in inhibiting rheumatoid arthritis through TLR4-NF-κB pathway Fu Y, Gao C, Sun X, Zhao Y, Zhang H J Orthop Surg Res 13-Jan-2024
PMCID:PMC10787417
doi:10.1186/s13018-024-04551-z
PMID:38218891
Screening of the key response component groups and mechanism verification of Huangqi-Guizhi-Wuwu-Decoction in treating rheumatoid arthritis based on a novel computational pharmacological model Liu Q, Luo Q, Fan Q, Li Y, Lu A, Guan D BMC Complement Med Ther 02-Jan-2024
PMCID:PMC10759359
doi:10.1186/s12906-023-04315-y
PMID:38166916
Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pathway to improve knee cartilage degeneration Wang YH, Zhou Y, Gao X, Sun S, Xie YZ, Hu YP, Fu Y, Fan XH, Xie Q PLoS One 02-Jan-2024
PMCID:PMC10760926
doi:10.1371/journal.pone.0290925
PMID:38166086
Network-based identification and mechanism exploration of active ingredients against Alzheimer’s disease via targeting endoplasmic reticulum stress from traditional chinese medicine Dai Z, Hu T, Wei J, Wang X, Cai C, Gu Y, Hu Y, Wang W, Wu Q, Fang J Comput Struct Biotechnol J 20-Dec-2023
PMCID:PMC10796977
doi:10.1016/j.csbj.2023.12.017
PMID:38261917
Complementary authentication of Chinese herbal products to treat endometriosis using DNA metabarcoding and HPTLC shows a high level of variability Mück F, Scotti F, Mauvisseau Q, Raclariu-Manolică AC, Schrøder-Nielsen A, Wangensteen H, de Boer HJ Front Pharmacol 05-Dec-2023
PMCID:PMC10728824
doi:10.3389/fphar.2023.1305410
PMID:38116075
Efficacy and safety of the integration of traditional Chinese medicine and western medicine in the treatment of diabetes-associated cognitive decline: a systematic review and meta-analysis Su J, Sun G, An J, Ao Y, Li J, Shen Z, Zhang L, Zhang S, Yang Y, Shi Y Front Pharmacol 22-Nov-2023
PMCID:PMC10703163
doi:10.3389/fphar.2023.1280736
PMID:38074157
An updated meta-analysis of Chinese herbal medicine for the prevention of COVID-19 based on Western-Eastern medicine Hu S, Luo D, Zhu Q, Pan J, Chen B, Furian M, Harkare HV, Sun S, Fansa A, Wu X, Yu B, Ma T, Wang F, Shi S Front Pharmacol 13-Nov-2023
PMCID:PMC10693348
doi:10.3389/fphar.2023.1257345
PMID:38044944

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives
3-Phenylpropanal 7707 Click to see C1=CC=C(C=C1)CCC=O 134.17 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
Protocatechuic Acid 72 Click to see 154.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoyl derivatives
2-Methoxybenzaldehyde 8658 Click to see COC1=CC=CC=C1C=O 136.15 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Styrenes
Styrene 7501 Click to see C=CC1=CC=CC=C1 104.15 unknown via CMAUP database
> Benzenoids / Phenol ethers / Anisoles
Anethole, (Z)- 1549040 Click to see CC=CC1=CC=C(C=C1)OC 148.20 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
Cassiferaldehyde 44178761 Click to see 178.18 unknown via CMAUP database
Coniferaldehyde 5280536 Click to see 178.18 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty aldehydes
Tetradecanal 31291 Click to see 212.37 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Linalool 6549 Click to see 154.25 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
phenylethyl-1-O-beta-D-apiofuranosyl-(1->4)-beta-D-glucopyranoside 44178762 Click to see 416.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
Cinnacasolide A 70692598 Click to see 446.40 unknown via CMAUP database
Cinnacasolide C 70694646 Click to see 586.50 unknown via CMAUP database
Dihydromelilotoside 5316728 Click to see 328.31 unknown via CMAUP database
Methyl Dihydromelilotoside 46881368 Click to see COC(=O)CCC1=CC=CC=C1OC2C(C(C(C(O2)CO)O)O)O 342.34 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Monosaccharides / Hexoses
Dihydrocinnacasside 44178764 Click to see C1=CC=C(C(=C1)CCC(=O)OC2C(C(C(C(O2)CO)O)O)O)O 328.31 unknown via CMAUP database
> Organoheterocyclic compounds / Dihydrofurans / Furanones / Butenolides
(1S,8R,10S)-3,8-dimethyl-5,9,15-trioxatetracyclo[11.2.1.02,6.08,10]hexadeca-2(6),3,13(16)-trien-14-one 163099902 Click to see 260.28 unknown https://doi.org/10.1016/S0040-4020(01)83309-3
Linderalactone 6450191 Click to see 244.28 unknown https://doi.org/10.1021/NP100874F
https://doi.org/10.1016/S0040-4020(01)83308-1
Neolinderan 595425 Click to see 260.28 unknown https://doi.org/10.1021/NP100874F
> Organoheterocyclic compounds / Dioxanes / 1,4-dioxanes
[(1R,4R,6S,7R,13S,14R)-6,11-dimethyl-16-oxo-5,9,15,17-tetraoxapentacyclo[11.2.2.01,14.04,6.08,12]heptadeca-8(12),10-dien-7-yl] acetate 162966188 Click to see 334.30 unknown https://doi.org/10.1016/S0040-4020(01)83310-X
> Phenylpropanoids and polyketides / Cinnamaldehydes
2-Hydroxycinnamaldehyde 5318169 Click to see 148.16 unknown via CMAUP database
Cinnamaldehyde 637511 Click to see 132.16 unknown via CMAUP database
cis-Cinnamaldehyde 6428995 Click to see 132.16 unknown via CMAUP database
O-Methoxycinnamaldehyde, (E)- 641298 Click to see COC1=CC=CC=C1C=CC=O 162.18 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Cinnamic acid esters
Ethyl cinnamate 637758 Click to see CCOC(=O)C=CC1=CC=CC=C1 176.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Cinnamic acids
Cinnamic acid 444539 Click to see C1=CC=C(C=C1)C=CC(=O)O 148.16 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives / Coumaric acids
2-Methoxycinnamic acid 734154 Click to see COC1=CC=CC=C1C=CC(=O)O 178.18 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
O-Coumaric Acid 637540 Click to see 164.16 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamyl alcohols
Cinnamyl Alcohol 5315892 Click to see 134.17 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives
Coumarin 323 Click to see 146.14 unknown via CMAUP database
Thamnosmonin 312089 Click to see 276.28 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
Procyanidin B 130556 Click to see 578.50 unknown via CMAUP database
Procyanidin B1 11250133 Click to see C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O 578.50 unknown via CMAUP database
Procyanidin B2, (+)- 122738 Click to see C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O 578.50 unknown via CMAUP database
Procyanidin C1 169853 Click to see 866.80 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins / Catechin gallates
(-)-Epicatechin gallate 107905 Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O 442.40 unknown via CMAUP database

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