Neolinderan

Details

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Internal ID e46e9bd3-4f1c-4a89-85b1-bac45b4bf037
Taxonomy Organoheterocyclic compounds > Dihydrofurans > Furanones > Butenolides
IUPAC Name 3,8-dimethyl-5,9,15-trioxatetracyclo[11.2.1.02,6.08,10]hexadeca-2(6),3,13(16)-trien-14-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C15H16O4/c1-8-7-17-11-6-15(2)12(19-15)4-3-9-5-10(13(8)11)18-14(9)16/h5,7,10,12H,3-4,6H2,1-2H3
InChI Key NJMLHRWYACXVHJ-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C15H16O4
Molecular Weight 260.28 g/mol
Exact Mass 260.10485899 g/mol
Topological Polar Surface Area (TPSA) 52.00 Ų
XlogP 2.00

Synonyms

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Neolinderane
NJMLHRWYACXVHJ-UHFFFAOYSA-N
(1aS,7R,11aS)-1a,2,3,7,11,11a-Hexahydro-8,11a-dimethyl-5H-7,4-methenofuro[3,2-c]oxireno[f]oxacycloundecin-5-one
10.beta.H-Germacra-4,7,11-trien-15-oic acid, 1.beta.,10:8,12-diepoxy-6.alpha.-hydroxy-, .gamma.-lactone
5H-7,4-Methenofuro[3,2-c]oxireno[f]oxacycloundecin-5-one, 1a,2,3,7,11,11a-hexahydro-8,11a-dimethyl-, [1aR-(1aR*,7R*,11aR*)]-
5H-7,4-Methenofuro[3,2-c]oxireno[f]oxacycloundecin-5-one, 1a,2,3,7,11,11a-hexahydro-8,11a-dimethyl-, [1aR-(1aR,7R,11aR)]-

2D Structure

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2D Structure of Neolinderan

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.74% 95.56%
CHEMBL4040 P28482 MAP kinase ERK2 88.82% 83.82%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.96% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.30% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.37% 99.23%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 86.21% 91.11%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 85.72% 95.34%
CHEMBL2581 P07339 Cathepsin D 83.21% 98.95%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.99% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.49% 86.33%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.25% 93.04%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.31% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Lindera chunii
Neolitsea cassia
Neolitsea hiiranensis
Neolitsea villosa

Cross-Links

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PubChem 595425
LOTUS LTS0133064
wikiData Q105180208