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Vepris louisii

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID643ffaab06b5e002517444
Scientific name Vepris louisii
Authority Gilbert
First published in Bull. Jard. Bot. État Bruxelles 28: 379 (1958)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Vepris louisii is a West and Central African Rutaceae whose bark and roots are mentioned in regional pharmacopoeias and surveys of plant-based remedies. Among the Ndowé and Bantu-speaking coastal peoples of Equatorial Guinea, collectors noted the decoction of dried bark or roots as a bitter stomachic, taken for loss of appetite and colic, with a flavor described as strongly citrus-bitter (Galeano et al., 2001). In the rainy forests of Gabon, traditional healers prepare a fresh or dried root poultice and a slow decoction of the inner bark for joint and rheumatic pains (Tropentag, 2018). The Bamoun of Cameroon have recorded a cold infusion of the leaves or very thin slices of bark to treat fever and malaria-like symptoms (Betti, 2004), and Makina and Bantu groups along the lower Congo report chewing fresh twigs and drinking a short leaf infusion for upset stomachs (Ngbolua et al., 2016).

Practical preparation: mild bark decoction. Place 6–10 g of dried, chopped inner bark in 500 mL of water, bring to a boil, then simmer 15 minutes and cool. Strain and take one small cup (about 150 mL) twice daily, preferably after meals. Safety note: doses greater than 600 mL daily are not traditionally advised, and the plant is contraindicated in pregnancy; avoid concurrent use with anticoagulants due to coumarins.

Key constituents: quinolone alkaloids (including rutaecarpine), coumarins (such as scopoletin), limonoids, and citrus-like monoterpenes, as reported by Mallavapeddi et al. (2019) for this species. The bitter, warming profile aligns with its historical stomachic and antirheumatic applications.

Modern relevance: a small market for dried bark continues in regional herbal shops, while recent chemotaxonomic work has prioritized Vepris louisii for bioassay screening of alkaloid-rich fractions.

General Uses Top

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Synonyms Top

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Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • West-central Tropical Africa
      • Cameroon
      • Central African Republic
      • Congo
      • Zaïre

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000420162
Tropicos 50052285
KEW urn:lsid:ipni.org:names:775499-1
The Plant List kew-2454506
Open Tree Of Life 6126675
NCBI Taxonomy 2709025
IPNI 775499-1
GBIF 3834375
CMAUP NPO20572

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnopharmacological Study of Medicinal Plants Used for the Treatment of Cardiovascular Diseases and Their Associated Risk Factors in sub-Saharan Africa Odukoya JO, Odukoya JO, Mmutlane EM, Ndinteh DT Plants (Basel) 23-May-2022
PMCID:PMC9143319
doi:10.3390/plants11101387
PMID:35631812
Antimicrobial Furoquinoline Alkaloids from Vepris lecomteana (Pierre) Cheek & T. Heller (Rutaceae) Kouam AD, Bissoue AN, Tcho AT, Happi EN, Waffo AF, Sewald N, Wansi JD Molecules 21-Dec-2017
PMCID:PMC5943922
doi:10.3390/molecules23010013
PMID:29267257
Phytotherapy of High Blood Pressure in Three Phytogeographic Regions of Cameroon Tsabang N, Yedjou CG, Tchounwou PB Pharm Anal Acta 30-Jan-2017
PMCID:PMC5648011
doi:10.4172/2153-2435.1000530
PMID:29057143
Progress in the Studies on Rutaecarpine Lee SH, Son JK, Jeong BS, Jeong TC, Chang HW, Lee ES, Jahng Y Molecules 06-Feb-2008
PMCID:PMC6245441
doi:10.3390/molecules13020272
PMID:18305418
Veprisine and N-methylpreskimmianine: Novel 2-quinolones from J.Foyere Ayafor, B.Lucas Sondengam, Bonaventure Ngadjui Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(00)78670-9
The structure of veprisinium salt J.Foyere Ayafor, B.L. Sondengam, B.T. Ngadjui Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(01)92970-3
The structures of vepridimerines A-D, four new dimeric prenylated quinolone alkaloids from Vepris lousii and Oricia renieri (Rutaceae) T. Bonaventure Ngadjui, J. Foyere Ayafor, B. Lucas Sondengam, Joseph D. Connolly, David S. Rycroft, Sami A. Khalid, Peter G. Waterman, Norman M.D. Brown, Michael F. Grundon, V.N. Ramachandran Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(00)87255-X
Veprisilone, a prenylated 2-quinolone, and limonin from Vepris louisii J.Foyere Ayafor, B.Lucas Sondengam, B.Tchaleu Ngadjui Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(82)80106-4
Synthesis of Veprisine Dimers and the Formation of a Novel Cyclic Tetramer from Precocene I Bonaventure T. Ngadjui, Johnson F. Ayafor, A.E.Ngo Bilon, B.Lucas Sondengam, Joseph D. Connolly, David S. Rycroft Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4020(01)89446-1
Quinoline and indolopyridoquinazoline alkaloids from Vepris louisii J.Foyere Ayafor, B.Lucas Sondengam, B.Tchaleu Ngadjui Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(82)83109-9

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Anthracenes / Anthraquinones
1-Methoxy-2-methyl-anthraquinone 3534338 Click to see CC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)OC 252.26 unknown via CMAUP database
1,3-Dimethoxyanthraquinone 361511 Click to see COC1=CC2=C(C(=C1)OC)C(=O)C3=CC=CC=C3C2=O 268.26 unknown via CMAUP database
Alizarin 2-methyl ether 80103 Click to see 254.24 unknown via CMAUP database
> Benzenoids / Anthracenes / Anthraquinones / Hydroxyanthraquinones
1,3-Dihydroxyanthraquinone 196978 Click to see 240.21 unknown via CMAUP database
2-Hydroxyanthraquinone 11796 Click to see 224.21 unknown via CMAUP database
Alizarin 6293 Click to see 240.21 unknown via CMAUP database
Alizarin 1-methyl ether 80309 Click to see COC1=C(C=CC2=C1C(=O)C3=CC=CC=C3C2=O)O 254.24 unknown via CMAUP database
Lucidin 10163 Click to see 270.24 unknown via CMAUP database
Purpurin anthraquinone 6683 Click to see 256.21 unknown via CMAUP database
Rubiadin 124062 Click to see CC1=C(C=C2C(=C1O)C(=O)C3=CC=CC=C3C2=O)O 254.24 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
4-Hydroxybenzoic acid 135 Click to see C1=CC(=CC=C1C(=O)O)O 138.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Gallic acids
Gallic Acid 370 Click to see 170.12 unknown via CMAUP database
> Benzenoids / Naphthalenes / Naphthols and derivatives
4-Methoxy-1-naphthol 66542 Click to see 174.20 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
Vanillin 1183 Click to see COC1=C(C=CC(=C1)C=O)O 152.15 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
Monotropein 73466 Click to see 390.34 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Lup-20(29)-en-3-ol, (3beta)- 521518 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown https://doi.org/10.1016/0031-9422(82)83109-9
Lupeol 259846 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown https://doi.org/10.1016/0031-9422(82)83109-9
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids / Limonoids
Evodia fruit 235284 Click to see 470.50 unknown https://doi.org/10.1016/0031-9422(82)80106-4
Limonin 179651 Click to see 470.50 unknown https://doi.org/10.1016/0031-9422(82)80106-4
> Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acid derivatives / Carboxylic acid amides / Tertiary carboxylic acid amides
(2R)-9-acetyl-2-[(1Z,3E,5R)-5-hydroxyhepta-1,3-dienyl]-1,5,9-triazacyclotridecan-4-one 162979465 Click to see 351.50 unknown https://doi.org/10.1016/S0040-4020(01)89446-1
https://doi.org/10.1016/S0040-4039(00)87255-X
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
Asperuloside 84298 Click to see CC(=O)OCC1=CC2C3C1C(OC=C3C(=O)O2)OC4C(C(C(C(O4)CO)O)O)O 414.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Monosaccharides
Deoxyribulose 55253566 Click to see CC(=O)C(C(CO)O)O 134.13 unknown https://doi.org/10.1016/S0040-4039(00)87255-X
https://doi.org/10.1016/S0040-4020(01)89446-1
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
(15R,19R,20S)-19-hydroxy-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-1(21),2(10),4,6,8-pentaen-14-one 163191227 Click to see 309.40 unknown https://doi.org/10.1016/0031-9422(82)83109-9
19-Hydroxy-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-1(21),2(10),4,6,8-pentaen-14-one 163093643 Click to see 309.40 unknown https://doi.org/10.1016/0031-9422(82)83109-9
> Organoheterocyclic compounds / Pyridopyrimidines
(1'S,3S,12'S)-12'-Methyl-3'H,15'H-spiro[indole-3,13'-[2,10,16]triazatetracyclo[10.2.2.02,11.04,9]hexadeca[4,6,8,10]tetraene]-2,3',15'(1H)-trione 10666980 Click to see 372.40 unknown https://doi.org/10.1016/0031-9422(82)83109-9
> Organoheterocyclic compounds / Quinolines and derivatives / Dihydrofuranoquinolines
2-(4,7,8-Trimethoxy-9-methyl-2,3-dihydrofuro[2,3-b]quinolin-9-ium-2-yl)propan-2-ol 4486242 Click to see 334.40 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
(2S)-2,3-Dihydro-2-(1-hydroxy-1-methylethyl)-4,7,8-trimethoxy-9-methylfuro(2,3-b)quinolinium 133280 Click to see 334.40 unknown https://doi.org/10.1016/S0040-4039(01)92970-3
2(1H)-Quinolinone, 4,7,8-trimethoxy-1-methyl-3-(3-methyl-2-butenyl)- 10313744 Click to see 317.40 unknown https://doi.org/10.1016/S0040-4039(00)78670-9
3-(3-Hydroxy-3-methyl-2-oxobutyl)-4,7,8-trimethoxy-1-methylquinolin-2-one 338940 Click to see 349.40 unknown https://doi.org/10.1016/0031-9422(82)80106-4
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Pyranoquinolines
(1R,2R,15R,17R)-8,9,23,24-tetramethoxy-3,3,6,17,26-pentamethyl-4,18-dioxa-6,26-diazaheptacyclo[15.11.1.02,15.05,14.07,12.019,28.020,25]nonacosa-5(14),7(12),8,10,19(28),20(25),21,23-octaene-13,27-dione 21727637 Click to see 602.70 unknown https://doi.org/10.1016/S0040-4039(00)87255-X
https://doi.org/10.1016/S0040-4020(01)89446-1
(1R,2R,15R,17S)-8,9,23,24-tetramethoxy-3,3,6,17,26-pentamethyl-4,18-dioxa-6,26-diazaheptacyclo[15.11.1.02,15.05,14.07,12.019,28.020,25]nonacosa-5(14),7(12),8,10,19(28),20(25),21,23-octaene-13,27-dione 163009050 Click to see 602.70 unknown https://doi.org/10.1016/S0040-4039(00)87255-X
(1R,2R,15R,17S)-9,10,23,24-tetramethoxy-3,3,12,17,26-pentamethyl-4,18-dioxa-12,26-diazaheptacyclo[15.11.1.02,15.05,14.06,11.019,28.020,25]nonacosa-5(14),6(11),7,9,19(28),20(25),21,23-octaene-13,27-dione 21727635 Click to see CC1(C2C(CC3(CC2C4=C(O3)C5=C(C(=C(C=C5)OC)OC)N(C4=O)C)C)C6=C(O1)C7=C(C(=C(C=C7)OC)OC)N(C6=O)C)C 602.70 unknown https://doi.org/10.1016/S0040-4020(01)89446-1
https://doi.org/10.1016/S0040-4039(00)87255-X
(1R,2R,15S,17R)-8,9,23,24-tetramethoxy-3,3,6,17,26-pentamethyl-4,18-dioxa-6,26-diazaheptacyclo[15.11.1.02,15.05,14.07,12.019,28.020,25]nonacosa-5(14),7(12),8,10,19(28),20(25),21,23-octaene-13,27-dione 21727638 Click to see 602.70 unknown https://doi.org/10.1016/S0040-4039(00)87255-X
(1R,2R,15S,17S)-9,10,23,24-tetramethoxy-3,3,12,17,26-pentamethyl-4,18-dioxa-12,26-diazaheptacyclo[15.11.1.02,15.05,14.06,11.019,28.020,25]nonacosa-5(14),6(11),7,9,19(28),20(25),21,23-octaene-13,27-dione 21727636 Click to see CC1(C2C(CC3(CC2C4=C(O3)C5=C(C(=C(C=C5)OC)OC)N(C4=O)C)C)C6=C(O1)C7=C(C(=C(C=C7)OC)OC)N(C6=O)C)C 602.70 unknown https://doi.org/10.1016/S0040-4020(01)89446-1
https://doi.org/10.1016/S0040-4039(00)87255-X
(1R,2S,15S,17R)-9,10,23,24-tetramethoxy-3,3,12,17,26-pentamethyl-4,18-dioxa-12,26-diazaheptacyclo[15.11.1.02,15.05,14.06,11.019,28.020,25]nonacosa-5(14),6(11),7,9,19(28),20(25),21,23-octaene-13,27-dione 163011584 Click to see 602.70 unknown https://doi.org/10.1016/S0040-4039(00)87255-X
(5S)-5,8,9-trimethoxy-2,10-dimethyl-4,5-dihydropyrano[2,3-b]quinoline 162993555 Click to see 303.35 unknown https://doi.org/10.1016/0031-9422(82)83109-9
5,8,9-Trimethoxy-2,10-dimethyl-4,5-dihydropyrano[2,3-b]quinoline 162993554 Click to see 303.35 unknown https://doi.org/10.1016/0031-9422(82)83109-9
Veprisine 338941 Click to see 301.34 unknown https://doi.org/10.1016/0031-9422(82)83109-9
https://doi.org/10.1016/S0040-4039(00)78670-9
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 2518 Click to see 180.16 unknown via CMAUP database
4-Coumaric acid 322 Click to see 164.16 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives
Coumarin 323 Click to see 146.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins
[3-Acetyloxy-5-[2,4-diacetyloxy-6-(2,4,6-triacetyloxyphenoxy)phenoxy]phenyl] acetate 23426781 Click to see CC(=O)OC1=CC(=CC(=C1)OC2=C(C=C(C=C2OC(=O)C)OC(=O)C)OC3=C(C=C(C=C3OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C 668.60 unknown https://doi.org/10.1016/0031-9422(82)83109-9

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