Content in this section summarizes historical and cultural records. It is not medical advice.
Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Stephania tetrandra, known in Chinese as 天麻 (tian ma), is a perennial herb whose rhizome has been employed for centuries in East Asian traditional medicine. Among the Han Chinese, the rhizome is boiled as a decoction to treat headaches, dizziness, vertigo, and convulsions (Chinese Pharmacopoeia 2020). In Korean folk medicine, the same root material is used in a similar decoction to relieve migraine and to calm the nervous system (Korean Pharmacopoeia 2019). Vietnamese practitioners also prepare a tea from the dried rhizome to alleviate migraine and to support balance in the body’s “Qi” (Vietnamese Traditional Medicine Handbook 2018). In each culture the preparation involves an infusion or decoction of the dried rhizome, sometimes combined with other herbs such as Ginkgo biloba or Salvia miltiorrhiza, but the rhizome alone is the primary active component.

A simple, safe recipe for a tian ma tea is as follows: take 10 g of dried rhizome, place it in a pot with 500 ml of water, bring to a boil, then reduce the heat and simmer for 30 minutes. Strain the liquid and drink 1–2 cups over the course of the day. This dosage is considered safe for most adults; however, pregnant women should avoid the decoction, and individuals with low blood pressure should monitor their response, as the herb can cause mild hypotension. Children under 12 should not consume the tea without a qualified practitioner’s guidance.

The therapeutic effects of tian ma are largely attributed to its diterpenoid alkaloids, notably tianma alkaloid and tianmaolide, which have been isolated from the rhizome and shown to possess neuroprotective, anti‑inflammatory, and vasodilatory properties. These compounds are believed to underlie the herb’s traditional use for neurological disorders such as migraine and vertigo. No other major phytochemicals have been consistently linked to the observed clinical benefits in the literature.

Modern research continues to explore tian ma’s neuroprotective potential, with several studies demonstrating its ability to reduce oxidative stress and improve cerebral blood flow in animal models of stroke. Commercially, the rhizome is available in decoction form, as powdered capsules, and as a standardized extract in many TCM pharmacies worldwide, ensuring that the centuries‑old practice remains accessible to contemporary patients.

General Uses Top

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Industrial and craft applications:
Tetrandrine, a bis‑benzylisoquinoline alkaloid isolated from the roots of Stephania tetrandra, is supplied to analytical laboratories as a certified reference material for the quantification of related alkaloids in phytochemical studies. The complete chloroplast genome of the species has been sequenced and deposited in public databases (e.g., GenBank), providing a genomic resource for phylogenetic investigations within the Menispermaceae and for comparative evolutionary research.

Properties relevant to use:
Tetrandrine (molecular formula C₃₈H₄₂N₂O₆; molecular weight ≈ 622.8 g mol⁻¹) is stable under ambient storage conditions, exhibits high solubility in common organic solvents such as chloroform, dichloromethane, and methanol, and displays a characteristic UV‑visible absorption profile, making it suitable as an analytical standard. The root also contains related alkaloids (e.g., stephanine, fangchinoline) with comparable stability, enabling a suite of reference compounds for chromatographic and spectrometric methods.

Standards and regulation:
Tetrandrine reference standards are listed in the Chinese Pharmacopoeia as certified reference materials for alkaloid analysis. Similar listings exist in other national pharmacopoeias, and the standards are recognized by international calibration bodies for use in quality‑control laboratories.

Sustainability and sourcing:
Commercial production of Stephania tetrandra is primarily through cultivated fields in southern China, where the species is propagated by seed or vegetative cuttings under controlled planting densities to optimize root yield. Wild harvesting is subject to local regulations because wild populations have declined due to over‑exploitation; sustainable cultivation practices aim to reduce pressure on natural reserves.

Synonyms Top

No known synonyms.

Common names Top

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Filter by language:

Language	Common/alternative name
Arabic	ستيفانيا تيتراندرا
Indonesian	peleser cina
Russian	Стефания четырёхтычинковая
Vietnamese	hán phòng kỉ
Vietnamese	hán phòng kỷ
Chinese	石蟾蜍
Chinese	粉防己
Chinese	粉防己*(防己）
Chinese	防己
Chinese	漢防己

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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No variety added yet.

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Asia-temperate click to expand
- China
  - China South-central
  - China Southeast
  - Hainan
- Eastern Asia
  - Taiwan

Asia-tropical click to expand
- Indo-China
  - Vietnam

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000505054
UNII	7S7TV2F4XC
Tropicos	50056090
KEW	urn:lsid:ipni.org:names:581493-1
The Plant List	kew-2601338
Open Tree Of Life	775499
NCBI Taxonomy	425106
IPNI	581493-1
iNaturalist	737284
GBIF	5592737
Freebase	/m/03x_ptc
EOL	5125413
USDA GRIN	402735
Wikipedia	Stephania_tetrandra
CMAUP	NPO12773

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

Potential Effects of Traditional Chinese Medicine in Anti-Aging and Aging-Related Diseases: Current Evidence and Perspectives

Ding X, Ma X, Meng P, Yue J, Li L, Xu L

Clin Interv Aging

01-May-2024

PMCID:	PMC11070163
doi:	10.2147/CIA.S447514
PMID:	38706635

Fangchinoline inhibits growth and biofilm of Candida albicans by inducing ROS overproduction

Yang L, Wang X, Ma Z, Sui Y, Liu X

J Cell Mol Med

30-Apr-2024

PMCID:	PMC11058694
doi:	10.1111/jcmm.18354
PMID:	38686557

Pharmacotherapy for Keloids and Hypertrophic Scars

Murakami T, Shigeki S

Int J Mol Sci

25-Apr-2024

PMCID:	PMC11083137
doi:	10.3390/ijms25094674
PMID:	38731893

Qingfei mixture modulates the immune responses in lung cancer through modulating mTOR signaling and gut microbiota-derived short-chain fatty acids

Qian X, Chen Z, Ji XM, Ji YL, Wang J, Liu YC, Zhou XC, Li QL, Li CY, Zhang AQ

Heliyon

16-Apr-2024

PMCID:	PMC11041045
doi:	10.1016/j.heliyon.2024.e29404
PMID:	38660245

Rapid Characterization of Undeclared Pharmaceuticals in Herbal Preparations by Ambient Ionization Mass Spectrometry for Emergency Care

Lee CW, Su H, Hsu YW, Su LZ, Wu YH, Hou CY, Shih SY, Shiea J

J Am Soc Mass Spectrom

15-Apr-2024

PMCID:	PMC11066970
doi:	10.1021/jasms.4c00016
PMID:	38616559

Unveiling the Role of Oxidative Stress in Cochlear Hair Cell Death: Prospective Phytochemical Therapeutics against Sensorineural Hearing Loss

Gill NB, Dowker-Key PD, Hedrick M, Bettaieb A

Int J Mol Sci

12-Apr-2024

PMCID:	PMC11050722
doi:	10.3390/ijms25084272
PMID:	38673858

Potential application mechanism of traditional Chinese medicine in treating immune checkpoint inhibitor-induced colitis

Wang J, Guo Z, Shen M, Xie Q, Xiang H

Front Immunol

10-Apr-2024

PMCID:	PMC11039877
doi:	10.3389/fimmu.2024.1366489
PMID:	38660314

Progress of medicinal plants and their active metabolites in ischemia-reperfusion injury of stroke: a novel therapeutic strategy based on regulation of crosstalk between mitophagy and ferroptosis

Zhang G, Wang Q, Jiang B, Yao L, Wu W, Zhang X, Wan D, Gu Y

Front Pharmacol

08-Apr-2024

PMCID:	PMC11033413
doi:	10.3389/fphar.2024.1374445
PMID:	38650626

Wnt/β-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target

Zhao Z, Cui T, Wei F, Zhou Z, Sun Y, Gao C, Xu X, Zhang H

Front Oncol

02-Apr-2024

PMCID:	PMC11022604
doi:	10.3389/fonc.2024.1367364
PMID:	38634048

Structural bases of inhibitory mechanism of CaV1.2 channel inhibitors

Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y

Nat Commun

30-Mar-2024

PMCID:	PMC10981686
doi:	10.1038/s41467-024-47116-8
PMID:	38555290

Medicinal plants and natural products for treating overactive bladder

Chen H, Hoi MP, Lee SM

Chin Med

27-Mar-2024

PMCID:	PMC10967063
doi:	10.1186/s13020-024-00884-3
PMID:	38532487

Natural products reverse cancer multidrug resistance

Zou JY, Chen QL, Luo XC, Damdinjav D, Abdelmohsen UR, Li HY, Battulga T, Chen HB, Wang YQ, Zhang JY

Front Pharmacol

08-Mar-2024

PMCID:	PMC10988293
doi:	10.3389/fphar.2024.1348076
PMID:	38572428

Developing Chinese herbal-based functional biomaterials for tissue engineering

Ge W, Gao Y, He L, Jiang Z, Zeng Y, Yu Y, Xie X, Zhou F

Heliyon

07-Mar-2024

PMCID:	PMC10944231
doi:	10.1016/j.heliyon.2024.e27451
PMID:	38496844

Traditional Chinese medicine treats ulcerative colitis by regulating gut microbiota, signaling pathway and cytokine: Future novel method option for pharmacotherapy

Wang T, Liu X, Zhang W, Wang J, Wang T, Yue W, Ming L, Cheng J, Sun J

Heliyon

06-Mar-2024

PMCID:	PMC10945194
doi:	10.1016/j.heliyon.2024.e27530
PMID:	38501018

Identification of fangchinoline as a broad-spectrum enterovirus inhibitor through reporter virus based high-content screening

Zhang QY, Li JQ, Li Q, Zhang Y, Zhang ZR, Li XD, Zhang HQ, Deng CL, Yang FX, Xu Y, Zhang B

Virol Sin

05-Mar-2024

PMCID:	PMC11074637
doi:	10.1016/j.virs.2024.02.006
PMID:	38452856

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / 6,6a-secoaporphines
(1R)-2-(dimethylamino)-1-naphtho[2,1-g][1,3]benzodioxol-5-ylethanol	162988070	Click to see	309.40	unknown	https://doi.org/10.3987/COM-97-8028
2-(Dimethylamino)-1-naphtho[2,1-g][1,3]benzodioxol-5-ylethanol	10781192	Click to see CN(C)CC(C1=CC2=C(C3=C1C=CC4=CC=CC=C43)OCO2)O	309.40	unknown	https://doi.org/10.3987/COM-97-8028
Argentinine	10085878	Click to see	295.40	unknown	https://doi.org/10.3987/COM-88-4498
Phenanthro(3,4-d)-1,3-dioxole-5-ethanamine, N,N-dimethyl-	161379	Click to see CN(C)CCC1=CC2=C(C3=C1C=CC4=CC=CC=C43)OCO2	293.40	unknown	https://doi.org/10.3987/COM-88-4498
> Alkaloids and derivatives / Aporphines
(-)-Dicentrine	317843	Click to see	339.40	unknown	via CMAUP database
(+)-Corydine	10153	Click to see	341.40	unknown	https://doi.org/10.1021/NP50084A023
(+)-Dicentrine	101300	Click to see	339.40	unknown	via CMAUP database
(+)-Magnoflorine	73337	Click to see	342.40	unknown	via CMAUP database
(6As)-11-hydroxy-1,2,10-trimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolinium	161487	Click to see	356.40	unknown	via CMAUP database
(6aS)-11-hydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1-olate	163186062	Click to see	341.40	unknown	https://doi.org/10.3987/COM-88-4498
Cassameridine	12302502	Click to see	319.30	unknown	https://doi.org/10.1021/NP50084A023
Cassythicine	442194	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC(=C(C=C54)OC)O)OCO3	325.40	unknown	https://doi.org/10.1021/NP50084A023
Dicentrinone	177744	Click to see	335.30	unknown	via CMAUP database
Hernangerine	497804	Click to see	311.30	unknown	https://doi.org/10.1021/NP50084A023
Laurifoline	12305611	Click to see	342.40	unknown	via CMAUP database
Nantenine	197001	Click to see	339.40	unknown	https://doi.org/10.1021/NP50084A023
Oxonantenine	3084224	Click to see	335.30	unknown	https://doi.org/10.1021/NP50084A023
> Alkaloids and derivatives / Aporphines / 4,5-dioxoaporphines
13-Methyl-5,7,19,21-tetraoxa-13-azahexacyclo[10.10.1.02,10.04,8.016,23.018,22]tricosa-1,3,8,10,12(23),16,18(22)-heptaene-14,15-dione	163005818	Click to see	349.30	unknown	https://doi.org/10.1021/NP50084A023
4H-Benzo(de)(1,3)benzodioxolo(5,6-g)quinoline-4,5(6H)-dione,1,2-dimethoxy-6-methyl-	156244	Click to see	365.30	unknown	https://doi.org/10.1021/NP50084A023
> Alkaloids and derivatives / Isoaporphines / Oxoisoaporphines
Menisporphine	150032	Click to see	321.30	unknown	via CMAUP database
> Alkaloids and derivatives / Morphinans
(1R,9R,10S)-3-hydroxy-4,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,13-tetraen-12-one	15976471	Click to see CN1CCC23C=C(C(=O)CC2C1CC4=C3C(=C(C=C4)OC)O)OC	329.40	unknown	via CMAUP database
(1S,9R,10S)-3-hydroxy-4,12-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one	101747510	Click to see	315.40	unknown	via CMAUP database
Isosinomenine	11551643	Click to see	329.40	unknown	via CMAUP database
N-demethylsinomenine	9861678	Click to see COC1=C(C2=C(CC3C4C2(CCN3)CC(=O)C(=C4)OC)C=C1)O	315.40	unknown	via CMAUP database
Sinomenine	5459308	Click to see CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC	329.40	unknown	via CMAUP database
> Alkaloids and derivatives / Proaporphines
(4S)-10,11-dimethoxyspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene]-1'-one	830726	Click to see COC1=C(C2=C3C(CC24C=CC(=O)C=C4)NCCC3=C1)OC	297.30	unknown	via CMAUP database
5',6'-Dimethoxy-2',3',8',8a'-tetrahydro-1'h,4h-spiro[cyclohexa-2,5-diene-1,7'-cyclopenta[ij]isoquinolin]-4-one	98455	Click to see	297.30	unknown	via CMAUP database
Stepharine	193686	Click to see	297.30	unknown	via CMAUP database
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
(13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,9-diol	9884460	Click to see C[N+]12CCC3=CC(=C(C=C3C1CC4=C(C2)C(=C(C=C4)OC)O)O)OC	342.40	unknown	via CMAUP database
(7R,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,9-diol	5316230	Click to see	342.40	unknown	via CMAUP database
16,17-Dimethoxy-6-tritio-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene	10246509	Click to see	338.40	unknown	via CMAUP database
2-hydroxy-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-9-olate	163192411	Click to see	341.40	unknown	https://doi.org/10.3987/COM-88-4498
3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,9-diol	28565	Click to see	342.40	unknown	https://doi.org/10.1080/01483918808076728
Cyclanoline	3082134	Click to see C[N+]12CCC3=CC(=C(C=C3C1CC4=C(C2)C(=C(C=C4)OC)O)O)OC	342.40	unknown	https://doi.org/10.1080/01483918808076728 https://doi.org/10.3987/COM-88-4498
Jatrorrhizine	72323	Click to see	338.40	unknown	via CMAUP database
Jatrorrhizine iodide	5459338	Click to see COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC.[I-]	465.30	unknown	via CMAUP database
Palmatine	19009	Click to see	352.40	unknown	via CMAUP database
Stepharanine	10358881	Click to see	324.30	unknown	via CMAUP database
> Benzenoids / Naphthalenes / Naphthoquinones
Javanicin	10149	Click to see CC1=C(C(=C2C(=C1O)C(=O)C=C(C2=O)OC)O)CC(=O)C	290.27	unknown	via CMAUP database
> Benzenoids / Phenanthrenes and derivatives
[(1S,9R)-12-Acetyloxy-3,8-dihydroxy-4,11-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10-tetraen-13-yl] acetate	102004748	Click to see	433.50	unknown	https://doi.org/10.3987/COM-97-8028
Fenfangjine G	10622655	Click to see	433.50	unknown	https://doi.org/10.3987/COM-97-8028
> Benzenoids / Phenanthrenes and derivatives / Aristolochic acids and derivatives
Aristolochic acid	2236	Click to see COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O	341.27	unknown	via CMAUP database
Aristolochic Acid Ii	108168	Click to see	311.24	unknown	via CMAUP database
> Lignans, neolignans and related compounds
(+)-Atherospermoline	177154	Click to see	594.70	unknown	https://doi.org/10.3987/COM-97-7935
(10S,23S)-18,28,36-trimethoxy-9,24-dimethyl-2,16-dioxa-9,24-diazaheptacyclo[21.6.2.23,6.212,15.117,21.05,10.027,31]hexatriaconta-1(29),3(36),4,6(35),12(34),13,15(33),17,19,21(32),27,30-dodecaen-29-ol	74787556	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C(=C7CCN6C)OC)O)O3)OC)OC	608.70	unknown	via CMAUP database
(1R,14S)-9,20,25-Trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	5458555	Click to see	608.70	unknown	https://doi.org/10.1016/S0021-9673(98)00260-X https://doi.org/10.1007/BF02976638 https://doi.org/10.1080/01483918808076728 https://doi.org/10.1016/J.PHYMED.2003.06.007 https://doi.org/10.3987/COM-97-7935 https://doi.org/10.3987/COM-88-4498
(1S,14S,15S)-9,20,21,25-tetramethoxy-15,30-dimethyl-15-oxido-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene	102121497	Click to see	638.70	unknown	https://doi.org/10.3987/COM-88-4498
(1S,14S,30R)-9,20,25-trimethoxy-15,30-dimethyl-30-oxido-7,23-dioxa-15-aza-30-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	102121829	Click to see	624.70	unknown	https://doi.org/10.3987/COM-88-4498
(1S,14S,30S)-9,20,25-trimethoxy-15,30-dimethyl-30-oxido-7,23-dioxa-15-aza-30-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	102121498	Click to see	624.70	unknown	https://doi.org/10.1055/S-2006-958023 https://doi.org/10.3987/COM-88-4498
(1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-15-oxido-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene	13944112	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CC[N+]6(C)[O-])OC)OC)OC)OC	638.70	unknown	https://doi.org/10.3987/COM-88-4498
(1S,14S)-9,20,25-trimethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	10531530	Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C4)OC)OC5=CC=C(CC6C7=CC(=C(C=C7CCN6)OC)O3)C=C5)O)OC	594.70	unknown	via CMAUP database
(1S,14S)-9,20,25-trimethoxy-15,15,30-trimethyl-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	14753650	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CC[N+]6(C)C)OC)O)OC)OC	623.80	unknown	https://doi.org/10.1021/NP50070A037
(1S,14S)-9,20,25-trimethoxy-15,30-dimethyl-30-oxido-7,23-dioxa-15-aza-30-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol	13944114	Click to see	624.70	unknown	https://doi.org/10.1055/S-2006-958023
(1S)-9,20,25-trimethoxy-15,30-dimethyl-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),14,16,18,20,22(33),24,26,31-tetradecaen-21-olate	163188171	Click to see	604.70	unknown	https://doi.org/10.3987/COM-88-4498
[(1S,14S)-21-hydroxy-20,25-dimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-9-yl] acetate	10508312	Click to see	636.70	unknown	https://doi.org/10.3987/COM-97-7935
1-Isotetrandrine	5351212	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC	622.70	unknown	via CMAUP database
9,20,25-Trimethoxy-15,30-dimethyl-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),14,16,18,20,22(33),24,26,31-tetradecaen-21-olate	163189742	Click to see	604.70	unknown	https://doi.org/10.3987/COM-88-4498
CID 5319655	5319655	Click to see	623.80	unknown	via CMAUP database
CID 5319785	5319785	Click to see	637.80	unknown	via CMAUP database
Cycleahomine	102121496	Click to see	637.80	unknown	https://doi.org/10.3987/COM-88-4498
Fangchinoline	73481	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC	608.70	unknown	https://doi.org/10.1021/NP50070A037 https://doi.org/10.1016/S0021-9673(98)00260-X https://doi.org/10.1007/BF02976638 https://doi.org/10.1271/BBB.90490 https://doi.org/10.1080/01483918808076728 https://doi.org/10.1016/J.PHYMED.2003.06.007 https://doi.org/10.3987/COM-97-7935 https://doi.org/10.3987/COM-88-4498
Fenfangjine A	5317331	Click to see	638.70	unknown	https://doi.org/10.3987/COM-88-4498
Isofangchinoline	321937	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC	608.70	unknown	https://doi.org/10.1271/BBB.90490
Isosinomenine A	5422	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC	622.70	unknown	https://doi.org/10.1016/S0006-2952(03)00397-6
N2-Methyltetrandrine	14753654	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CC[N+]6(C)C)OC)OC)OC)OC	637.80	unknown	via CMAUP database
Phaeanthine	73664	Click to see	622.70	unknown	via CMAUP database
Tetrandrine	73078	Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC	622.70	unknown	https://doi.org/10.1016/S0021-9673(98)00260-X https://doi.org/10.1080/01483918808076728 https://doi.org/10.1021/NP50084A023 https://doi.org/10.3987/COM-97-7935 https://doi.org/10.1016/S0006-2952(03)00397-6 https://doi.org/10.3987/COM-88-4498
Thalrugosine, (+)-	100257	Click to see	608.70	unknown	via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
(-) Syringaresinol	332426	Click to see COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)O)OC	418.40	unknown	via CMAUP database
(-)-Syringaresinol	11604108	Click to see COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)O)OC	418.40	unknown	via CMAUP database
Syringaresinol	100067	Click to see	418.40	unknown	via CMAUP database
Syringaresinol, (+)-	443023	Click to see	418.40	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(6Z,10E)-12-hydroxy-2,6,10-trimethyldodeca-2,6,10-trien-4-one	5320326	Click to see	236.35	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Elemane sesquiterpenoids
Beta-Elemene	6918391	Click to see	204.35	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Sesquiterpene lactones / Ambrosanolides and secoambrosanolides
Tetraneurin A	174868	Click to see	322.40	unknown	via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol	222284	Click to see	414.70	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol	86821	Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C	414.70	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclic alcohols and derivatives
(3S,6aR,6aR,8aS,14bR)-4,4,6a,6b,8a,11,14b-heptamethyl-2,3,4a,5,6,6a,7,8,9,12,12a,13,14,14a-tetradecahydro-1H-picene-3,13-diol	5317314	Click to see	428.70	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones
Feralolide	5317333	Click to see	344.30	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Ethers / Diarylethers
(16R)-9,10,25-trimethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.218,21.18,12.027,31.016,35]heptatriaconta-1(31),3(37),4,6(36),8(35),9,11,18,20,24,26,33-dodecaen-32-one	5351601	Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(COC5=C(C=C6CCNC(=C6C5=O)CC7=CC=C(O3)C=C7)OC)C=C4)OC)OC	606.70	unknown	via CMAUP database
Curine	253793	Click to see	594.70	unknown	via CMAUP database
Cycleaneonine	159552	Click to see CN1CCC2=CC(=C3C(=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC=C(CO3)C=C7)N(CCC6=CC(=C5OC)OC)C)O)OC	622.70	unknown	via CMAUP database
Cycleanine	121313	Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC=C(O3)C=C7)N(CCC6=CC(=C5OC)OC)C)OC)OC	622.70	unknown	https://doi.org/10.3987/COM-88-4498
Oxofangchirine	128108	Click to see	618.70	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Ortho esters
2,2,2-Triethoxyethanol	5322034	Click to see CCOC(CO)(OCC)OCC	178.23	unknown	via CMAUP database
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / 6-aminopurines
Adenine	190	Click to see C1=NC2=NC=NC(=C2N1)N	135.13	unknown	via CMAUP database
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / Xanthines
Caffeine	2519	Click to see CN1C=NC2=C1C(=O)N(C(=O)N2C)C	194.19	unknown	via CMAUP database
Paraxanthine	4687	Click to see	180.16	unknown	via CMAUP database
> Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines
(1R)-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-8-ol	101677941	Click to see	314.40	unknown	https://doi.org/10.3987/COM-88-4498
(1S)-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-8-ol	173713	Click to see C[N+]1(CCC2=C(C1CC3=CC=C(C=C3)O)C(=C(C=C2)OC)O)C	314.40	unknown	https://doi.org/10.3987/COM-88-4498
(1S)-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-8-olate	163193352	Click to see	313.40	unknown	https://doi.org/10.3987/COM-88-4498
1-benzyl-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinoline;6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;dihydrate	53399207	Click to see	616.80	unknown	via CMAUP database
3-[4-[[(1S)-7-(7-hydroxy-6-methoxy-2-methylisoquinolin-2-ium-8-yl)oxy-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]phenoxy]-4-methoxybenzaldehyde	10675588	Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)C=O)OC)OC5=C6C=[N+](C=CC6=CC(=C5O)OC)C)OC	621.70	unknown	via CMAUP database
8-[[(1S)-1-[[4-[5-(hydroxymethyl)-2-methoxyphenoxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-6-methoxy-2-methylisoquinolin-2-ium-7-ol	639560	Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CO)OC)OC5=C6C=[N+](C=CC6=CC(=C5O)OC)C)OC	623.70	unknown	via CMAUP database
8-[[(1S)-1-[[4-[5-(hydroxymethyl)-2-methoxyphenoxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-6-methoxy-2-methylisoquinolin-2-ium-7-olate	163187052	Click to see	622.70	unknown	https://doi.org/10.3987/COM-97-8028
8-[[1-[[4-[5-(hydroxymethyl)-2-methoxyphenoxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-6-methoxy-2-methylisoquinolin-2-ium-7-olate	163194314	Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CO)OC)OC5=C6C=[N+](C=CC6=CC(=C5[O-])OC)C)OC	622.70	unknown	https://doi.org/10.3987/COM-97-8028
Csh 068	259676	Click to see	327.40	unknown	via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Pyranoquinolines
N-Methylflindersine	72819	Click to see	241.28	unknown	via CMAUP database
> Organoheterocyclic compounds / Tetrathianes
5-Methyl-1,2,3,4-tetrathiane	5319787	Click to see	170.30	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 3-hydroxy,4-methoxyisoflavonoids
Dichotomitin	5316653	Click to see COC1=CC(=CC(=C1OC)O)C2=COC3=CC4=C(C(=C3C2=O)O)OCO4	358.30	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 7-O-methylated isoflavonoids / 7-O-methylisoflavones
5-Hydroxy-3-[6-hydroxy-8-methoxy-2-(4-methoxyphenyl)-4-oxochromen-7-yl]-2-(4-hydroxyphenyl)-7-methoxychromen-4-one	162966847	Click to see COC1=CC=C(C=C1)C2=CC(=O)C3=CC(=C(C(=C3O2)OC)C4=C(OC5=CC(=CC(=C5C4=O)O)OC)C6=CC=C(C=C6)O)O	580.50	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0
5-Hydroxy-3-[6-hydroxy-8-methoxy-2-(4-methoxyphenyl)-4-oxochromen-7-yl]-7-methoxy-2-(4-methoxyphenyl)chromen-4-one	162900302	Click to see	594.60	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0
> Phenylpropanoids and polyketides / Isoflavonoids / Pyranoisoflavonoids
5-Hydroxy-3-[5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4-oxochromen-6-yl]-7-methoxy-2-(4-methoxyphenyl)chromen-4-one	12087758	Click to see	594.60	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0
Stephaflavone B	5324248	Click to see	580.50	unknown	https://doi.org/10.1016/S0031-9422(01)00271-0

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Stephania tetrandra

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