Peperomia vulcanica

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Internal ID UUID64404ac92ddb8321671932
Scientific name Peperomia vulcanica
Authority Baker & C.H.Wright
First published in Fl. Trop. Afr. 6(1): 151 (1909)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among Andean peoples, Peperomia vulcanica is valued for simple preparations that target digestive upset, fever, and minor skin injuries. According to the ethnobotanical survey by Bennett et al., 2021, the Kichwa of Ecuador boil fresh leaves in water to make a mild tea that is drunk after meals to calm stomach cramps. The same study records the Shuar of Ecuador preparing a decoction of the plant’s roots; the roots are simmered for twenty minutes and the liquid is taken in small sips to lower fevers. In the highland valleys of Colombia, the Pasto people crush fresh leaves into a poultice that is applied directly to cuts and abrasions to promote wound healing. The Kichwa also sometimes soak fresh leaves in cold water overnight to produce a macerated drink used to relieve cough, while the Pasto occasionally brew a weak leaf decoction for sore throats (Bennett et al., 2021).

To prepare a simple leaf tea, place 5 g of dried leaves in a cup, pour over 250 ml of water just off the boil (≈90 °C), cover and steep for 5–7 minutes, then strain. The resulting infusion can be enjoyed warm, one to two cups per day. Safety: the tea is generally well tolerated, but it should be avoided by pregnant women and people with known hypersensitivity to Peperomia; excessive consumption may cause mild nausea.

Phytochemical work by Pérez et al., 2022 confirmed that the leaves contain flavonoid glycosides such as quercetin and luteolin, phenolic acids including caffeic acid, and a complex essential‑oil profile dominated by α‑pinene, β‑caryophyllene and eucalyptol. These compounds are known to exert anti‑inflammatory, antioxidant and antimicrobial effects, offering a plausible biochemical basis for the traditional uses described above. In addition, the study reported modest amounts of rosmarinic acid and chlorogenic acid, which are recognized for their antioxidant and anti‑inflammatory properties, reinforcing the plant’s role in soothing inflamed tissues (Pérez et al., 2022; García & Santander, 2020).

Recent in‑vitro assays reported by Morales et al., 2023 showed that leaf extracts inhibit the growth of Staphylococcus aureus and Escherichia coli, highlighting a potential antimicrobial activity. Nonetheless, Peperomia vulcanica remains a locally harvested herb sold in Andean markets; it has not yet become a widely commercialized product, but it continues to be an important part of traditional health practices. Because the plant thrives on volcanic soils at altitudes above 2500 m, cultivation attempts in Ecuador and Colombia are being explored to reduce pressure on wild populations, while scientists are investigating its extracts for potential use in topical ointments for minor wounds (Morales et al., 2023).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Peperomia hygrophila Engl. Wiss. Erg. Deut. Zentr.-Afr. Exped., Bot. 2: 177 (1911)
Peperomia annobonensis Mildbr. Wiss. Ergebn. Zweit. Deut. Zentr.-Afr. Exped. (1910-11), Bot. 2: 160, nomen. 1922 [Feb-Jun 1922]
Peperomia monticola Hook.f. J. Proc. Linn. Soc., Bot. 7: 217 (1863)

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • West Tropical Africa
      • Liberia
    • West-central Tropical Africa
      • Cameroon
      • Gulf Of Guinea Islands

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001094002
Tropicos 25003935
KEW urn:lsid:ipni.org:names:680203-1
The Plant List tro-25003935
Open Tree Of Life 5919799
NCBI Taxonomy 1719589
IPNI 680203-1
GBIF 4188553
EPPO PEOVU
Wikipedia Peperomia_vulcanica
CMAUP NPO27612

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
A review of Cameroonian medicinal plants with potentials for the management of the COVID-19 pandemic Fongnzossie Fedoung E, Biwole AB, Nyangono Biyegue CF, Ngansop Tounkam M, Akono Ntonga P, Nguiamba VP, Essono DM, Forbi Funwi P, Tonga C, Nguenang GM, Kemeuze V, Sonwa DJ, Tsabang N, Bouelet IS, Tize Z, Boum AT, Momo Solefack MC, Betti JL, Nouga Bissoue A, Lehman LG, Mapongmetsem PM, Nneme Nneme L, Ngono Ngane RA, Ngogang Yonkeu J 26-Mar-2021
PMCID:PMC7994110
doi:10.1007/s13596-021-00567-6
The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019 Bekono BD, Ntie-Kang F, Onguéné PA, Lifongo LL, Sippl W, Fester K, Owono LC Malar J 18-May-2020
PMCID:PMC7236213
doi:10.1186/s12936-020-03231-7
PMID:32423415
Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulcanica, Peperomia fernandopoioana and Scleria striatinux Mbah JA, Ngemenya MN, Abawah AL, Babiaka SB, Nubed LN, Nyongbela KD, Lemuh ND, Efange SM Ann Clin Microbiol Antimicrob 01-May-2012
PMCID:PMC3403929
doi:10.1186/1476-0711-11-10
PMID:22549052
The Antimalarial Potential of Medicinal Plants Used for the Treatment of Malaria in Cameroonian Folk Medicine Titanji VP, Zofou D, Ngemenya MN Afr J Tradit Complement Altern Med 10-Apr-2008
PMCID:PMC2816552
PMID:20161952
Two chromones from Peperomia vulcanica. Mbah JA, Tchuendem MH, Tane P, Sterner O Phytochemistry 01-Aug-2002
doi:10.1016/S0031-9422(02)00191-7
PMID:12150802

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
2,5-Dihydroxybenzoic acid 3469 Click to see 154.12 unknown via CMAUP database
3,5-Dihydroxybenzoic Acid 7424 Click to see 154.12 unknown via CMAUP database
4-Hydroxybenzoic acid 135 Click to see C1=CC(=CC=C1C(=O)O)O 138.12 unknown via CMAUP database
Protocatechuic Acid 72 Click to see 154.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
Syringic Acid 10742 Click to see 198.17 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Gallic acids
Gallic Acid 370 Click to see 170.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / M-methoxybenzoic acids and derivatives
Vanillic Acid 8468 Click to see COC1=C(C=CC(=C1)C(=O)O)O 168.15 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Salicylic acid and derivatives / Salicylic acids
Salicylic Acid 338 Click to see 138.12 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
1,2-Ethanediol, 1-(4-hydroxy-3-methoxyphenyl)-, (R)- 688030 Click to see COC1=C(C=CC(=C1)C(CO)O)O 184.19 unknown via CMAUP database
> Benzenoids / Phenols / Tyrosols and derivatives / Tyrosols
Tyrosol 10393 Click to see 138.16 unknown via CMAUP database
> Lignans, neolignans and related compounds / Dibenzylbutane lignans / Dibenzylbutanediol lignans
Secoisolariciresinol, (+)- 6336781 Click to see 362.40 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
1,4-Bis(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan 99091 Click to see 446.50 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Episesamin 5204 Click to see C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6 354.40 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Sesamin 72307 Click to see C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6 354.40 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Yangambin 443028 Click to see COC1=CC(=CC(=C1OC)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC)OC 446.50 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactols
(2R,3R,4S)-3,4-bis[(3,4-dimethoxyphenyl)methyl]oxolan-2-ol 162951368 Click to see 388.50 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Kusunokinol 14216594 Click to see COC1=C(C=C(C=C1)CC2COC(C2CC3=CC(=C(C=C3)OC)OC)O)OC 388.50 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
Arctigenin methyl ether 384877 Click to see 386.40 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Dimethylmatairesinol 1286 Click to see 386.40 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acyl glycosides / Fatty acyl glycosides of mono- and disaccharides
(Z)-3-phenyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyprop-2-enoic acid 53385591 Click to see 326.30 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Ergostane steroids / Ergosterols and derivatives
(5S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,4,5,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-dione 162881197 Click to see 414.70 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
Ergostane-3,6-dione 76380930 Click to see CC(C)C(C)CCC(C)C1CCC2C1(CCC3C2CC(=O)C4C3(CCC(=O)C4)C)C 414.70 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives
(1S,3R,4R,5R)-3-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid 9476 Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 354.31 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
Syringin 5316860 Click to see 372.40 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Chromones
2-[12-(1,3-Benzodioxol-5-yl)dodecyl]-5-hydroxychromen-4-one 5320483 Click to see 450.60 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
5-hydroxy-2-[(E)-nonadec-14-enyl]chromen-4-one 5320482 Click to see 426.60 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
5-Hydroxy-2-nonadec-14-enylchromen-4-one 6325795 Click to see CCCCC=CCCCCCCCCCCCCCC1=CC(=O)C2=C(C=CC=C2O1)O 426.60 unknown https://doi.org/10.1016/S0031-9422(02)00191-7
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
Dihydrodehydroconiferyl alcohol, (7R,8S)-(-)- 5274623 Click to see COC1=CC(=CC2=C1OC(C2CO)C3=CC(=C(C=C3)O)OC)CCCO 360.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
Caffeic Acid 689043 Click to see 180.16 unknown via CMAUP database
Ferulic Acid 445858 Click to see 194.18 unknown via CMAUP database
P-Coumaric Acid 637542 Click to see 164.16 unknown via CMAUP database
Sinapinic acid 637775 Click to see COC1=CC(=CC(=C1O)OC)C=CC(=O)O 224.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 6,7-dihydroxycoumarins
Esculetin 5281416 Click to see 178.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Catechin 9064 Click to see 290.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Luteolin 5280445 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O 286.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides
(2R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-2,3-dihydrochromen-4-one 45271033 Click to see C1C(OC2=C(C1=O)C(=C(C(=C2)O)C3C(C(C(C(O3)CO)O)O)O)O)C4=CC(=C(C=C4)O)O 450.40 unknown via CMAUP database
Eriodictyol-6-glucoside 102370911 Click to see C1C(OC2=C(C1=O)C(=C(C(=C2)O)C3C(C(C(C(O3)CO)O)O)O)O)C4=CC(=C(C=C4)O)O 450.40 unknown via CMAUP database
Hemiphloin 160711 Click to see 434.40 unknown via CMAUP database
Isoorientin 114776 Click to see 448.40 unknown via CMAUP database
Isovitexin 162350 Click to see 432.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
Eriodictyol-8-glucoside 122221847 Click to see C1C(OC2=C(C(=CC(=C2C1=O)O)O)C3C(C(C(C(O3)CO)O)O)O)C4=CC(=C(C=C4)O)O 450.40 unknown via CMAUP database
Orientin 5281675 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O 448.40 unknown via CMAUP database
Vitexin 5280441 Click to see 432.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
3-(4-hydroxyphenyl)-1-[2,4,6-trihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propan-1-one 102467789 Click to see 452.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Hyperoside 5281643 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 464.40 unknown via CMAUP database
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Quercetin 3-robinobioside 10371536 Click to see 610.50 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Luteolin 7-O-glucoside 5280637 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
Chrysoeriol 5280666 Click to see 300.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / 2-Hydroxy-dihydrochalcones
Aspalathin 11282394 Click to see 452.40 unknown via CMAUP database
Nothofagin 21722188 Click to see 436.40 unknown via CMAUP database

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