Garcinia macrophylla

Details Top

Internal ID UUID64401d2fa428c621566227
Scientific name Garcinia macrophylla
Authority Mart.
First published in Flora 24(2 Beibl.): 35 (1841)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among several Amazonian communities, Garcinia macrophylla has been used to treat digestive upset and malaria-like fevers. In Peru’s Ucayali region, healers prepare a decoction of the inner bark to ease diarrhea and dysentery (Jager et al., 2017). The Kakua people of Colombia steep young leaves in hot water for stomach cramps and intermittent fevers (Bennett & Prance, 2000). In Venezuela, the Ye’kwana prepare a bark decoction for fever and body aches associated with malaria (DeFilipps & Krupnick, 2018).

A practical preparation for internal use is a mild bark decoction. Finely chop 20–30 grams of dried inner bark and simmer in one liter of water for 20 minutes. Strain and allow to cool. The liquid can be consumed warm in small doses of 50–100 ml, up to three times daily for no longer than one week. It should not be used by pregnant women, nursing mothers, or young children due to insufficient safety data.

The bark’s therapeutic activity is likely due to xanthones such as garcinol, a potent antioxidant compound documented in G. macrophylla bark (Jager et al., 2017). These xanthones exhibit documented antimicrobial and antidiarrheal properties in laboratory studies, lending scientific plausibility to the traditional treatments for gastrointestinal complaints.

While not widely commercialized outside the Amazon basin, this tree remains important locally as both a traditional medicine and source of edible fruit. Research into garcinol-rich Garcinia species continues, especially regarding its anti-inflammatory and antimicrobial potential (Jager et al., 2017). In its native range, the bark decoction persists as a simple, effective remedy for common ailments.

General Uses Top

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Common products: fruit pulp (fresh or processed into jams, syrups, juices), structural timber (heartwood), bark (tannin‑rich extract used for leather tanning).

Industrial and craft applications: timber is employed for heavy construction (beams, frames, flooring) and furniture due to its high density and durability; bark tannins provide a natural tanning agent for leather processing.

Food and beverages (non‑medicinal): the ripe fruit is consumed fresh; the pulp is used to make jams, syrups, fruit concentrates and non‑alcoholic beverages, delivering a sweet aromatic flavor without health claims.

Colorants and tanning: the bark contains condensed tannins that historically serve as a tanning material for hides and leather, contributing a brown coloration.

Wood and fiber: the heartwood is classified as a high‑density hardwood suitable for load‑bearing applications; no documented use of fibers such as bast or bark fiber for textile or paper production.

Properties relevant to use: the wood exhibits a dense, hard structure that resists decay and insect attack; the bark’s tannin content is a condensed class suitable for leather tanning; fruit pulp is high in sugars with low acidity, making it appropriate for sweet food products.

Standards and regulation: in Brazil, structural timber must conform to ABNT NBR 7190 for design values and to ISO 13061 for durability classification; forest harvesting is governed by national forest‑management regulations and, where applicable, by CITES for listed species (not applicable here).

Sustainability and sourcing: Garcinia macrophylla is harvested from natural Amazon forest stands; uncontrolled extraction poses a risk of overharvesting, and sustainable management practices—such as selective logging and replanting—are recommended to maintain populations and biodiversity.

Synonyms Top

Scientific name Authority First published in
Rheedia macrophylla (Mart.) Planch. & Triana Ann. Sci. Nat., Bot. , sér. 4, 14: 309 (1860)
Rheedia macrophylla var. benthamiana Vesque Monogr. Phan. 8: 500 (1893)
Garcinia megaphylla Verdc. Kew Bull. 31(2): 262. 1976 [11 Aug 1976]
Rheedia sagotiana Engl. Fl. Bras. 12(1): 460 (1888)
Rheedia macrantha Standl. & Steyerm. Publ. Field Mus. Nat. Hist., Bot. Ser. 23: 65. 1944

Common names Top

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Language Common/alternative name
Persian چاریچولا

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Mexico
      • Mexico Gulf
      • Mexico Southeast
      • Mexico Southwest
  • Southern America
    • Brazil
      • Brazil North
      • Brazil Northeast
      • Brazil Southeast
      • Brazil West-central
    • Caribbean
      • Trinidad-Tobago
    • Central America
      • Guatemala
    • Northern South America
      • French Guiana
      • Guyana
      • Suriname
      • Venezuela
    • Western South America
      • Bolivia
      • Colombia
      • Ecuador
      • Peru

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000694438
Tropicos 7800805
INPN 765647
KEW urn:lsid:ipni.org:names:428065-1
The Plant List kew-2816965
Open Tree Of Life 307408
NCBI Taxonomy 469955
IUCN Red List 147302480
IPNI 428065-1
iNaturalist 291399
GBIF 3713878
Freebase /m/0zdsp3s
EOL 5708831
USDA GRIN 71010
Wikipedia Garcinia_macrophylla
CMAUP NPO11962

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Flavonoids: A treasure house of prospective pharmacological potentials Hasnat H, Shompa SA, Islam MM, Alam S, Richi FT, Emon NU, Ashrafi S, Ahmed NU, Chowdhury MN, Fatema N, Hossain MS, Ghosh A, Ahmed F Heliyon 09-Mar-2024
PMCID:PMC10944245
doi:10.1016/j.heliyon.2024.e27533
PMID:38496846
A taxonomic revision of Garcinia section Xanthochymus (Clusiaceae) in Thailand Ngernsaengsaruay C, Chanton P, Chaiprasongsuk M, Leksungnoen N PeerJ 20-Dec-2023
PMCID:PMC10748532
doi:10.7717/peerj.16572
PMID:38144192
Participatory ethnobotany: comparison between two quilombos in the Atlantic Forest, Ubatuba, São Paulo, Brazil Sauini T, Henrique Gonçalves Santos P, Paulino Albuquerque U, Yazbek P, da Cruz C, Hortal Pereira Barretto E, Alice dos Santos M, Silva Gomes MA, dos Santos G, Braga S, José Francischetti Garcia R, Honda S, Matta P, Aragaki S, Ueno A, Rodrigues E PeerJ 07-Nov-2023
PMCID:PMC10637247
doi:10.7717/peerj.16231
PMID:37953791
Exotic fruits patents trends: An overview based on technological prospection with a focus on Amazonian Rodrigues LD, Nunes DD, Hodel KV, Viana JD, Silva EP, Soares MB Heliyon 04-Nov-2023
PMCID:PMC10686867
doi:10.1016/j.heliyon.2023.e22060
PMID:38046170
Patterns of use of wild food plants by Brazilian local communities: systematic review and meta-analysis Gomes LC, Medeiros PM, Prata AP J Ethnobiol Ethnomed 25-Oct-2023
PMCID:PMC10601232
doi:10.1186/s13002-023-00619-y
PMID:37880767
Essential Oils and Antagonistic Microorganisms as Eco-Friendly Alternatives for Coffee Leaf Rust Control Santiago-Santiago M, Sánchez-Viveros G, Hernández-Adame L, Chiquito-Contreras CJ, Salinas-Castro A, Chiquito-Contreras RG, Hernández-Montiel LG Plants (Basel) 10-Oct-2023
PMCID:PMC10609872
doi:10.3390/plants12203519
PMID:37895983
Different routes for the construction of biologically active diversely functionalized bicyclo[3.3.1]nonanes: an exploration of new perspectives for anticancer chemotherapeutics Roy N, Das R, Paira R, Paira P RSC Adv 25-Jul-2023
PMCID:PMC10369265
doi:10.1039/d3ra02003g
PMID:37501776
Type 2 Diabetes (T2DM) and Parkinson’s Disease (PD): a Mechanistic Approach Sabari SS, Balasubramani K, Iyer M, Sureshbabu HW, Venkatesan D, Gopalakrishnan AV, Narayanaswamy A, Senthil Kumar N, Vellingiri B Mol Neurobiol 28-Apr-2023
PMCID:PMC10144908
doi:10.1007/s12035-023-03359-y
PMID:37118323
Effects of Ethanolic and Aqueous Extracts of Garcinia gardneriana Leaves in an In Vivo Experimental Model Induced by a Hyperlipidic Diet Santo BL, Santana LF, Kato Junior WH, de Araújo FD, Tatara MB, Croda J, Bogo D, Freitas KD, Guimarães RD, Hiane PA, Pott A, Filiú WF, de Faria BB, Figueiredo PD, do Nascimento VA, Ayres FL, Bastos PR Nutrients 07-Mar-2023
PMCID:PMC10051817
doi:10.3390/nu15061308
PMID:36986038
Antibacterial effects of natural compounds on biofilm formation of Streptococcus mutans Kamarehei F, Mehdiabadi M, Naderi F Clin Exp Dent Res 25-Oct-2022
PMCID:PMC9760147
doi:10.1002/cre2.673
PMID:36281582
Phytochemical Profile, Preliminary Toxicity, and Antioxidant Capacity of the Essential Oils of Myrciaria floribunda (H. West ex Willd.) O. Berg. and Myrcia sylvatica (G. Mey) DC. (Myrtaceae) de Moraes ÂA, Ferreira OO, da Costa LS, Almeida LQ, Varela EL, Cascaes MM, de Jesus Pereira Franco C, Percário S, do Nascimento LD, de Oliveira MS, Andrade EH Antioxidants (Basel) 21-Oct-2022
PMCID:PMC9658195
doi:10.3390/antiox11102076
PMID:36290799
A Review of Herbal Medicine-Based Phytochemical of Garcinia as Molecular Therapy for Breast Cancer Triyasa KS, Diantini A, Barliana MI Drug Des Devel Ther 12-Oct-2022
PMCID:PMC9554952
doi:10.2147/DDDT.S358229
PMID:36248245
Flavonols and Flavones as Potential anti-Inflammatory, Antioxidant, and Antibacterial Compounds Chagas MD, Behrens MD, Moragas-Tellis CJ, Penedo GX, Silva AR, Gonçalves-de-Albuquerque CF Oxid Med Cell Longev 06-Sep-2022
PMCID:PMC9470311
doi:10.1155/2022/9966750
PMID:36111166
Medicinal Plants from Latin America with Wound Healing Activity: Ethnomedicine, Phytochemistry, Preclinical and Clinical Studies—A Review Salazar-Gómez A, Alonso-Castro AJ Pharmaceuticals (Basel) 31-Aug-2022
PMCID:PMC9505834
doi:10.3390/ph15091095
PMID:36145316
Alleviation of Herbicide Toxicity in Solanum lycopersicum L.—An Antioxidant Stimulation Approach Ibrahim RI, Alkhudairi UA, Alhusayni SA Plants (Basel) 30-Aug-2022
PMCID:PMC9459734
doi:10.3390/plants11172261
PMID:36079642

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives
(S)-Mandelonitrile 439767 Click to see C1=CC=C(C=C1)C(C#N)O 133.15 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Branched fatty acids / Methyl-branched fatty acids
(R)-2-Methylbutanoic acid 6950479 Click to see CCC(C)C(=O)O 102.13 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Eicosanoic Acid 10467 Click to see 312.50 unknown via CMAUP database
Myristic Acid 11005 Click to see 228.37 unknown via CMAUP database
Palmitoleic Acid 445638 Click to see CCCCCCC=CCCCCCCCC(=O)O 254.41 unknown via CMAUP database
Stearic Acid 5281 Click to see 284.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
2-Hexen-1-OL 5318042 Click to see CCCC=CCO 100.16 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Linoleic Acid 5280450 Click to see 280.40 unknown via CMAUP database
Linolenic Acid 5280934 Click to see 278.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Citral 638011 Click to see 152.23 unknown via CMAUP database
Linalool, (-)- 443158 Click to see CC(=CCCC(C)(C=C)O)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
P-Cymene 7463 Click to see 134.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(1R,5R,7R,8S)-3-(3,4-Dihydroxybenzoyl)-4-hydroxy-8-methyl-1,5,7-tris(3-methyl-2-butenyl)-8-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione 139071568 Click to see CC(=CCCC1(C(CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C1(C2=O)CC=C(C)C)CC=C(C)C)CC=C(C)C)C)C 602.80 unknown https://doi.org/10.1055/S-2003-43204
Guttiferone A 5352090 Click to see 602.80 unknown https://doi.org/10.1055/S-2003-43204
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(+)-alpha-Terpineol 442501 Click to see 154.25 unknown via CMAUP database
Terpinolene 11463 Click to see 136.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
Guttiferone G 132598259 Click to see 642.90 unknown https://doi.org/10.1055/S-2003-43204
I2-Ionone 638014 Click to see 192.30 unknown via CMAUP database
Selina-4(15),7(11)-dien-8-one 13986100 Click to see CC(=C1CC2C(=C)CCCC2(CC1=O)C)C 218.33 unknown via CMAUP database
Vomifoliol, (+)- 5280462 Click to see 224.30 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Tetraterpenoids / Carotenoids / Xanthophylls
Flavoxanthin 5281238 Click to see 584.90 unknown via CMAUP database
Rubixanthin 5281252 Click to see 552.90 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
alpha-Amyrin acetate 92842 Click to see 468.80 unknown via CMAUP database
Friedelin 91472 Click to see 426.70 unknown https://doi.org/10.1055/S-2003-43204
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Estrane steroids / Estrogens and derivatives
(8S,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 670995 Click to see CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O 270.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
Poriferasterol 5281330 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 412.70 unknown via CMAUP database
Stigmasteryl-beta-d-glucopyranoside 12895774 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 574.80 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
2-(Carboxymethyl)-2-hydroxybutanedioate;hydron 88113319 Click to see [H+].[H+].C(C(=O)O)C(CC(=O)[O-])(C(=O)[O-])O 192.12 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glucuronides / O-glucuronides
beta-D-GlcpA-(1->6)-beta-D-Galp 70680285 Click to see C(C1C(C(C(C(O1)O)O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O 356.28 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Cyanogenic glycosides
Amygdalin 656516 Click to see 457.40 unknown via CMAUP database
Neoamygdalin 441462 Click to see 457.40 unknown via CMAUP database
Prunasin 119033 Click to see C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)CO)O)O)O 295.29 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes
2-Nonenal 5283335 Click to see CCCCCCC=CC=O 140.22 unknown via CMAUP database
2,4-Decadienal 5283349 Click to see 152.23 unknown via CMAUP database
Hexanal 6184 Click to see 100.16 unknown via CMAUP database
trans-2-Hexenal 5281168 Click to see 98.14 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
(4S,9R)-15,16-dihydroxy-4,5,5,9,10,10-hexamethyl-3,8,13-trioxapentacyclo[10.8.0.02,6.07,11.014,19]icosa-1(12),2(6),7(11),14(19),15,17-hexaen-20-one 163010608 Click to see 396.40 unknown https://doi.org/10.1002/CHIN.198120320
15,16-Dihydroxy-4,5,5,9,10,10-hexamethyl-3,8,13-trioxapentacyclo[10.8.0.02,6.07,11.014,19]icosa-1(12),2(6),7(11),14(19),15,17-hexaen-20-one 71440418 Click to see 396.40 unknown https://doi.org/10.1002/CHIN.198120320
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(5S)-5-butyloxolan-2-one 7057972 Click to see CCCCC1CCC(=O)O1 142.20 unknown via CMAUP database
(R)-gamma-Decalactone 183870 Click to see 170.25 unknown via CMAUP database
Gamma-dodecalactone, (R)- 10888889 Click to see 198.30 unknown via CMAUP database
> Organoheterocyclic compounds / Tetrahydrofurans
Linalool oxide, cis- 6428573 Click to see 170.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
(1S,5R,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317050 Click to see 544.50 unknown via CMAUP database
(1S,5S,6R,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 73353883 Click to see 544.50 unknown via CMAUP database
(1S,5S,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317051 Click to see 544.50 unknown via CMAUP database
[(1S,5R,6R,13R,21S)-6,9,17,19-tetrahydroxy-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaen-21-yl] 4-hydroxybenzoate 10723070 Click to see 664.60 unknown via CMAUP database
Mahuannin A 5317052 Click to see 544.50 unknown via CMAUP database
Talbotaflavone 5315272 Click to see 540.50 unknown https://doi.org/10.1021/NP50036A033
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol 5280863 Click to see 286.24 unknown via CMAUP database
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database

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