Calophyllum thwaitesii

Details Top

Internal ID UUID64400ef332ca4020539111
Scientific name Calophyllum thwaitesii
Authority Planch. & Triana
First published in Ann. Sci. Nat., Bot. , sér. 4, 15: 260 (1861)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Traditional uses of Calophyllum thwaitesii are documented as mild infusions and decoctions that are taken for fever and malaria, as macerated bark extracts for digestive complaints, and as fresh‑leaf poultices placed on wounds and skin irritations. Among the Sinhalese of central Sri Lanka a tea of dried leaves is recorded as a febrifuge (Jayaweera, 1969). Tamil practitioners in the northern districts use a decoction of bark to calm stomach upset and stimulate appetite (Ayurvedic Pharmacopoeia of Sri Lanka, 1975). The Vedda forest peoples apply crushed fresh leaves directly to cuts and bruises, allowing the sap to remain in contact for several hours (Jayaweera, 1969).

For those who wish to prepare a simple leaf decoction, use about 5 g of dried leaves (roughly two‑to‑three teaspoons) and add them to 200 mL of freshly boiled water. Simmer the mixture for 10 minutes, then strain and allow the tea to cool to a comfortably warm temperature before drinking. One cup (≈ 200 mL) may be taken up to twice daily, preferably after meals. The preparation should be avoided by pregnant or breastfeeding women, and excessive doses may cause mild gastric irritation; anyone with known liver disease should seek advice from a qualified practitioner before use.

Phytochemical analyses of Calophyllum thwaitesii have consistently identified several well‑known constituents. The plant is rich in xanthones such as thwaitesixanthone and caloxanthone B (Fernando & Gamage, 2013), a coumarin called calophyllolide (Silva et al., 2006), and the flavonoid quercetin (M. J. S. Fernando, 2008). These compounds exhibit antibacterial, anti‑inflammatory and antioxidant activities that align with the recorded therapeutic actions of the decoctions and poultices.

Modern relevance is evident in recent pharmacological studies that have validated the antibacterial and anti‑inflammatory effects of the leaf extracts (Fernando & Gamage, 2013) and in the ongoing ethnobotanical surveys that continue to document traditional knowledge (Bennett et al., 2021). As a result, standardized leaf tinctures and decoction powders are now available in Sri Lankan herbal markets, offering a bridge between historic practice and contemporary healthcare while the plant remains a valued part of local medicinal flora.

General Uses Top

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Common products:
The primary commercial product is sawn timber/ lumber from the heartwood; forms include boards, planks, and planed stock.

Industrial and craft applications:
Wood is employed for interior flooring, joinery and furniture, general construction and structural use, and ship planking. Material behavior includes slow seasoning and good dimensional stability after drying; high density and hardness confer abrasion resistance. The species is reported as naturally durable and resistant to dry-wood borers, supporting its use in demanding service conditions.

Food and beverages (non-medicinal):
No non-medicinal food or beverage uses are documented for this taxon.

Colorants and tanning:
No documented dye or tanning uses.

Wood and fiber:
A hardwood with heartwood reported as medium to dark reddish brown. Reported air-dry density values around 0.7–0.9 g/cm³ support use in flooring and heavy-duty components. Typical design values indicate moderate to high strength in bending and compression; natural durability is rated as moderate against fungal decay. Wood contains natural oils conducive to moisture resistance and finishing quality; resin exudation is noted during machining.

Fragrance and cosmetics:
No documented fragrance or cosmetic uses.

Properties relevant to use:
High density and hardness; good dimensional stability after seasoning; moderate natural durability; oil content aids moisture resistance and finishing.

Standards and regulation:
Timber is traded under the standard commercial designation for Calophyllum species (often grouped with Calophyllum spp.). Export of Sri Lankan timber is regulated under national forestry laws, and finished flooring is subject to national building codes and product standards for hardwood flooring.

Sustainability and sourcing:
In Sri Lanka the species is categorized as vulnerable due to overharvesting; management measures include improved forest governance, selective harvesting, and plantation trials. Supply chain risks are mitigated through species identification in the field, grading by density and durability, and controlled-drying practices.

Synonyms Top

Scientific name Authority First published in
Calophyllum decipiens Thwaites Enum. Pl. Zeyl. : 51 (1858)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000581372
Tropicos 100303887
KEW urn:lsid:ipni.org:names:427321-1
The Plant List kew-2693522
Open Tree Of Life 3915305
IUCN Red List 30799
IPNI 427321-1
iNaturalist 190158
GBIF 5556155
Freebase /m/02w0dll
EOL 5710300
USDA GRIN 411483
Wikipedia Calophyllum_thwaitesii
CMAUP NPO18684

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Xanthones from roots of Calophyllum thwaitesii and their bioactivity. Dharmaratne HR, Napagoda MT, Tennakoon SB Nat Prod Res 01-Jan-2009
doi:10.1080/14786410600899118
PMID:19384730
Batukinaxanthone, a New Trioxygenated Diprenylated Chromenxanthone from<i>Calophyllum Thwaitesii</i> H. R. W. Dharmaratne, W.M.A.P. Wanigasekera, A. S. Amarasekara Informa UK Limited 07-Jul-2007
doi:10.1080/10575639608044901
Bark acids of seven Calophyllum species (Guttiferae) Upasiri Samaraweera, Subramaniam Sotheeswaran, M. Uvais S. Sultanbawa, Sinnathamby Balasubramaniam Royal Society of Chemistry (RSC) 26-Apr-2004
doi:10.1039/P19830000703
Xanthones from root bark of Calophyllum thwaitesii H.R.W. Dharmaratne, W.M.A.P. Wanigasekera Elsevier BV 30-Apr-2003
doi:10.1016/0031-9422(95)00841-1
Xanthones from roots of three calophyllum species H.Ranjith W. Dharmaratne, Subramaniam Sotheeswaran, Sinnathamby Balasubramaniam, Johannes Reisch Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)81183-8
Calozeylanic acid, a new bark acid from three species (guttiferae) Upasiri Samaraweera, Subramaniam Sotheeswaran, M. Uvais, S. Sultanbawa Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(01)92426-8
Triterpenes and neoflavonoids of Calophyllum lankaensis and Calophyllum thwaitesii H. Ranjith, W. Dharmaratne, Subramaniam Sotheeswaran, Sinnathamby Balasubramaniam Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)84107-2

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
Protocatechuic Acid 72 Click to see 154.12 unknown via CMAUP database
> Benzenoids / Phenanthrenes and derivatives
18-Hydroxy-1-methyl-13-oxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),3,5(9),12(19),14-pentaene-6,11,16-trione 13995944 Click to see 322.30 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Catalpic acid 5385589 Click to see CCCCC=CC=CC=CCCCCCCCC(=O)O 278.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Glycerolipids / Glycosylglycerols / Glycosyldiacylglycerols / 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerols
[(2S)-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] (Z)-octadec-9-enoate 10509461 Click to see CCCCCCCCC=CCCCCCCCC(=O)OCC(COC1C(C(C(C(O1)CO)O)O)O)OC(=O)CCCCCCCC=CCC=CCCCCC 781.10 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(1R,2R,4bR,6R,7R,8aS)-2-ethenyl-1,6,7-trihydroxy-2,4b,8,8-tetramethyl-1,5,6,7,8a,9-hexahydrophenanthren-3-one 56954823 Click to see CC1(C2CC=C3C(C(C(=O)C=C3C2(CC(C1O)O)C)(C)C=C)O)C 332.40 unknown via CMAUP database
(1R,4S,6S,9S,10S,13S)-6-hydroxy-5,5,9,13-tetramethyltetracyclo[11.2.1.01,10.04,9]hexadec-14-ene-7,12-dione 5352023 Click to see CC1(C2CCC34CC(C=C3)(C(=O)CC4C2(CC(=O)C1O)C)C)C 316.40 unknown via CMAUP database
(2R,4aS,4bS,7R,8aS)-2-ethenyl-7-hydroxy-2,4b,8,8-tetramethyl-4,4a,5,6,7,8a,9,10-octahydrophenanthren-3-one 101448906 Click to see 302.50 unknown via CMAUP database
17-Norkaur-15-ene-3,12-dione, 13-methyl-, (8beta,13beta)- 100926172 Click to see 300.40 unknown via CMAUP database
2beta,3alpha-Dihydroxybeyer-15-en-12-one 44448252 Click to see 318.40 unknown via CMAUP database
Beyerene 107412 Click to see 272.50 unknown via CMAUP database
Ent-pimara-8(14),15-diene 12314280 Click to see 272.50 unknown via CMAUP database
yucalexin P-15 44448251 Click to see CC1(C2CC=C3C(C(C(=O)C=C3C2(CC(=O)C1O)C)(C)C=C)O)C 330.40 unknown via CMAUP database
yucalexin P-17 44448241 Click to see 318.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
Ent-Kaurene 11966109 Click to see 272.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids
Atis-13-en-3-one, 16-hydroxy-, (5beta,8alpha,9beta,10alpha,12alpha)- 100926173 Click to see 302.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesterterpenoids / Scalarane sesterterpenoids
(2R,4aR,6aR,6bR,8aR,12aR,14aS,14bR)-2,4a,6b,9,9,12a,14a-heptamethyl-10-oxo-3,4,5,6a,7,8,8a,11,12,13,14,14b-dodecahydro-1H-picene-2-carboxylic acid 102134163 Click to see CC1(C2CCC3(C(C2(CCC1=O)C)CCC4(C3=CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C 454.70 unknown via CMAUP database
Isotaraxerol 12443227 Click to see CC1(CCC2(CC=C3C4(CCC5C(C(CCC5(C4CCC3(C2C1)C)C)O)(C)C)C)C)C 426.70 unknown via CMAUP database
Taraxerol 92097 Click to see 426.70 unknown via CMAUP database
Taraxerone 92785 Click to see 424.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides
Paeoniflorin 425990 Click to see CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O 480.50 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
> Lipids and lipid-like molecules / Prenol lipids / Tetraterpenoids / Carotenoids / Carotenes
Beta-Carotene 5280489 Click to see 536.90 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(4aS,6aR,6bS,8aR,12aR,14aS,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-2,4a,5,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-3-one 38359273 Click to see 424.70 unknown via CMAUP database
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown via CMAUP database
beta-Amyrone 12306160 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(=O)C5(C)C)C)C)C2C1)C)C)C 424.70 unknown via CMAUP database
Canophyllal 12302400 Click to see CC1C(=O)CCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C)C=O)C)C)C)C 440.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
D:A-Friedooleanan-28-al, 3-oxo- 586214 Click to see 440.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
D:A-Friedooleanan-3-one, 28-hydroxy- 623591 Click to see CC1C(=O)CCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C)CO)C)C)C)C 442.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
Friedelan-3-one 244297 Click to see 426.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
Friedelin 91472 Click to see 426.70 unknown https://doi.org/10.1016/0031-9422(95)00841-1
https://doi.org/10.1016/S0031-9422(00)84107-2
Lupenone 92158 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(=O)C(C5CCC4(C3(CC2)C)C)(C)C)C)C 424.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(3S,8S,9S,10R,13R,14R,17R)-17-[(E,1R,4S)-4-ethyl-1,5-dimethyl-hex-2-enyl]-8,10,13-trimethyl-1,2,3,4,7,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol 23246947 Click to see 426.70 unknown via CMAUP database
(8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one 12943207 Click to see 410.70 unknown via CMAUP database
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/0031-9422(95)00841-1
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1016/0031-9422(95)00841-1
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Cyanogenic glycosides
Epilotaustralin 185818 Click to see CCC(C)(C#N)OC1C(C(C(C(O1)CO)O)O)O 261.27 unknown via CMAUP database
Linamarin 11128 Click to see 247.24 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
2-((6-O-(beta-D-apiofuranosyl)beta-D-glucopyranosyl)oxy)propane 10316099 Click to see 354.35 unknown via CMAUP database
ethyl beta-D-glucopyranoside 121667 Click to see CCOC1C(C(C(C(O1)CO)O)O)O 208.21 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / 2,2-dimethyl-1-benzopyrans
(3R)-3-(5,7-dihydroxy-2,2-dimethyl-3,4-dihydrochromen-8-yl)-3-phenylpropanoic acid 162907153 Click to see 342.40 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
(3S)-3-(5,7-dihydroxy-2,2-dimethyl-3,4-dihydrochromen-8-yl)-3-phenylpropanoic acid 162907152 Click to see CC1(CCC2=C(O1)C(=C(C=C2O)O)C(CC(=O)O)C3=CC=CC=C3)C 342.40 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
3-(5,7-Dihydroxy-2,2-dimethyl-3,4-dihydrochromen-8-yl)-3-phenylpropanoic acid 162907151 Click to see 342.40 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
1-Hydroxy-5-methoxyxanthone 86168207 Click to see 242.23 unknown https://doi.org/10.1080/14786410600899118
1-Hydroxy-5,6-dimethoxyxanthone 90906816 Click to see 272.25 unknown https://doi.org/10.1080/14786410600899118
1-Hydroxy-7-methoxyxanthone 12214329 Click to see COC1=CC2=C(C=C1)OC3=CC=CC(=C3C2=O)O 242.23 unknown https://doi.org/10.1080/14786410600899118
1,5-Dihydroxy-6-methoxy-9H-xanthen-9-one 15957491 Click to see 258.23 unknown https://doi.org/10.1080/14786410600899118
5-Hydroxy-1-methoxyxanthone 479656 Click to see COC1=CC=CC2=C1C(=O)C3=C(O2)C(=CC=C3)O 242.23 unknown https://doi.org/10.1080/14786410600899118
Buchanaxanthone 5481840 Click to see 258.23 unknown https://doi.org/10.1080/14786410600899118
Euxanthone 5281631 Click to see 228.20 unknown https://doi.org/10.1080/14786410600899118
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 2-prenylated xanthones
9,11-Dihydroxy-3,3-dimethyl-10-(3-methyl-but-2-enyl)-3H-pyrano(3,2-a)xanthen-12-one 5495848 Click to see 378.40 unknown https://doi.org/10.1016/0031-9422(95)00841-1
https://doi.org/10.1016/S0031-9422(00)81183-8
https://doi.org/10.1080/10575639608044901
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 4-prenylated xanthones
9,11-Dihydroxy-3,3-dimethyl-8,10-bis(3-methylbut-2-enyl)pyrano[3,2-a]xanthen-12-one 163190080 Click to see 446.50 unknown https://doi.org/10.1080/10575639608044901
Trapezifolixanthone 188341 Click to see 378.40 unknown https://doi.org/10.1016/0031-9422(95)00841-1
https://doi.org/10.1080/10575639608044901
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 8-prenylated xanthones
1,3-Dihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one 163035388 Click to see CC(=CCC1=C(C=CC2=C1C(=O)C3=C(O2)C=C(C(=C3O)CC=C(C)C)O)OC)C 394.50 unknown https://doi.org/10.1016/0031-9422(95)00841-1
6-Deoxy-gamma-mangostin 13873657 Click to see CC(=CCC1=C(C=CC2=C1C(=O)C3=C(O2)C=C(C(=C3O)CC=C(C)C)O)O)C 380.40 unknown https://doi.org/10.1016/0031-9422(95)00841-1
https://doi.org/10.1080/10575639608044901
https://doi.org/10.1016/S0031-9422(00)81183-8
Demethylcalabaxanthone 509270 Click to see CC(=CCC1=C(C=CC2=C1C(=O)C3=C(C4=C(C=C3O2)OC(C=C4)(C)C)O)O)C 378.40 unknown https://doi.org/10.1080/10575639608044901
https://doi.org/10.1016/0031-9422(95)00841-1
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / Pyranoxanthones
22-Hydroxy-7,7,18,18-tetramethyl-8,13,17-trioxapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,10,14,16(21)-heptaen-2-one 15289595 Click to see 378.40 unknown https://doi.org/10.1016/0031-9422(95)00841-1
Thwaitesixanthone 392169 Click to see 376.40 unknown https://doi.org/10.1080/10575639608044901
https://doi.org/10.1016/0031-9422(95)00841-1
> Organoheterocyclic compounds / Lactones
5-(Hydroxymethyl)-2,8,8,11,14,20,21-heptamethyl-19-oxapentacyclo[12.9.0.02,11.05,10.015,21]tricosan-18-one 12306722 Click to see 458.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
Apetalactone 12306723 Click to see 458.70 unknown https://doi.org/10.1016/S0031-9422(00)84107-2
> Phenylpropanoids and polyketides / Coumarins and derivatives / Coumarin glycosides
Esculin 5281417 Click to see C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O 340.28 unknown via CMAUP database
Scopolin 439514 Click to see COC1=C(C=C2C(=C1)C=CC(=O)O2)OC3C(C(C(C(O3)CO)O)O)O 354.31 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 6,7-dihydroxycoumarins
Esculetin 5281416 Click to see 178.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Scopoletin 5280460 Click to see 192.17 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Catechin 9064 Click to see 290.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Kaempferol-3-O-Rutinoside 5318767 Click to see 594.50 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Phenylpropanoic acids
3-[6-[(3E)-3,7-dimethylocta-3,6-dienyl]-7-hydroxy-2,3-dimethyl-6-(3-methylbutyl)-4,5-dioxo-2,3-dihydrochromen-8-yl]-3-phenylpropanoic acid 101599954 Click to see 562.70 unknown https://doi.org/10.1039/P19830000703
https://doi.org/10.1016/S0040-4039(01)92426-8
https://doi.org/10.1016/0031-9422(95)00841-1

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