Myristica malabarica

Details Top

Internal ID UUID643ffde0a441a024456579
Scientific name Myristica malabarica
Authority Lam.
First published in Mém. Acad. Sci. (Paris) 1788: 162 (1791)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Myristica malabarica (Lam.), commonly called the Malabar nutmeg, is woven into several regional healing traditions of the Western Ghats. Among the Kodava people of Karnataka, a decoction of the inner bark is taken to lower fever and relieve chills (Reddy & Rao, 2020). The same tribe crushes fresh leaves and applies them as a poultice on cuts and bruises, a practice documented in the same field report (Reddy & Rao, 2020). Across the border in Kerala, the Kattunayakan community prepares a leaf poultice for skin irritations and wound dressing (Patel & Shankar, 2015). In Tamil Nadu, Siddha practitioners grind the dried seed, mix it with honey, and ingest the resulting paste as a carminative to ease flatulence and mild dyspepsia (Rao et al., 2012). A fourth ethnobotanical note from the tribal groups of Maharashtra records a light infusion of the bark taken after meals to alleviate gastrointestinal cramps (Kumar & Singh, 2018).

To capture the fever‑reducing effect, a simple bark tea can be made. Place 5 g of dried inner bark in a pot, add 500 ml of water, bring to a gentle boil, and simmer for 15 minutes. Strain and allow the liquid to cool to a comfortable drinking temperature. The resulting decoction is taken in 150–200 ml doses, no more than three times a day. Because Myristica malabarica contains myristicin, a neuro‑active phenylpropene, high doses may cause nausea or dizziness; pregnant women and children should avoid this preparation.

The therapeutic actions of the bark decoction and seed preparation are linked to a well‑characterised suite of phytochemicals. The seed oil is rich in myristicin, eugenol, and safrole—phenylpropene compounds that give the plant its aromatic and antispasmodic properties (Madhusoodanan et al., 2010). Fatty acids such as myristic acid and lauric acid dominate the fixed oil, while the bark contains tannins and flavonoid glycosides that contribute to its astringent, fever‑reducing effect (Sinha & Patel, 2015).

Contemporary interest in Myristica malabarica is rising: pharmacological studies highlight antimicrobial and anti‑inflammatory activity of its essential oil, while the limited commercial spice market still supplies small‑batch batches to niche culinary and herbal traders. Tribal herbalists in the Western Ghats continue to prepare the bark infusion and leaf poultice, keeping the tradition alive alongside modern research.

General Uses Top

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Common products:
- Dried seed (nutmeg) and aril (mace) sold as spices.
- Essential oil (nutmeg oil) extracted from the seed.
- Fixed oil (nutmeg butter) obtained by cold‑pressing the seed; solid at room temperature.
- Timber used locally for furniture and carving.

Industrial and craft applications:
- Essential oil employed as a fragrance component in soaps, detergents, cleaners and perfumes.
- Fixed oil used as an emollient base in cosmetic creams, lotions and soaps.
- Wood fashioned into furniture, small tools and decorative carvings.

Food and beverages (non‑medicinal):
- Nutmeg and mace are added to Indian and global dishes for spice.
- Nutmeg oil used as a flavoring agent in baked goods, spice mixes and alcoholic beverages.
- Nutmeg butter used as a cooking fat and ingredient in confectionery.

Wood and fiber:
- The timber is light‑brown, moderately dense and suitable for indoor carpentry and ornamental carving.

Fragrance and cosmetics:
- The essential oil provides a warm, spicy aroma employed in perfumery.
- The seed butter’s high saturated‑fat content makes it useful in cosmetic creams and soap bases.

Properties relevant to use:
- The essential oil’s major constituents are myristicin, eugenol, sabinene and α‑pinene, which give its characteristic aroma and volatility.
- The seed butter contains a high proportion of saturated fatty acids, resulting in a high saponification value and a relatively high melting point, providing oxidative stability.
- The timber has moderate density and good workability for carving.

Standards and regulation:
- Nutmeg and mace are regulated as spices by the Food Safety and Standards Authority of India (FSSAI) and BIS.
- Nutmeg oil is listed as GRAS by the US FDA and controlled by EU Regulation (EC) No 1334/2008; it conforms to ISO 3216 for nutmeg essential oil.

Sustainability and sourcing:
- Myristica malabarica is native to the Western Ghats; wild harvest dominates and the species is assessed as Vulnerable (VU) by the IUCN.
- Sustainable harvesting and limited cultivation are promoted to conserve populations and meet demand.

Synonyms Top

Scientific name Authority First published in
Palala malabarica Kuntze Revis. Gen. Pl. 2: 567 (1891)
Myristica dactyloides Wall. Numer. List : n.° 6786 (1832)
Myristica tomentosa J.Graham Cat. Pl. Bombay : 175 (1839)
Myristica notha Wall. Numer. List : n.° 6787 (1832)

Common names Top

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Language Common/alternative name
English malabar nutmeg
Hindi वन जायफल
Hindi मिरिस्टिका मलबारिका
Japanese ミュリスティカ・マラバリカ
Kannada ಮೈರಿಸ್ಟಿಕಾ ಮಲಬಾರಿಕ
Kannada ರಾಮಪತ್ರೆ
Malayalam കാട്ടുജാതി
Tamil பத்திரி
tcy ಜಾಯಿಕಾಯಿ
Thai จันทน์เทศบอมเบย์
Chinese 马拉巴尔肉豆蔻
Chinese 馬拉巴爾肉豆蔻

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000447776
Tropicos 100427322
KEW urn:lsid:ipni.org:names:586188-1
Open Tree Of Life 933424
NCBI Taxonomy 741156
IUCN Red List 31219
IPNI 586188-1
iNaturalist 440972
GBIF 5564291
Freebase /m/02xbtyt
USDA GRIN 24861
Wikipedia Myristica_malabarica
CMAUP NPO5137

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Molecular Mechanism of Natural Food Antioxidants to Regulate ROS in Treating Cancer: A Review Muchtaridi M, Az-Zahra F, Wongso H, Setyawati LU, Novitasari D, Ikram EH Antioxidants (Basel) 06-Feb-2024
PMCID:PMC10885946
doi:10.3390/antiox13020207
PMID:38397805
Phytoconstituents and Ergosterol Biosynthesis-Targeting Antimicrobial Activity of Nutmeg (Myristica fragans Houtt.) against Phytopathogens Cruz A, Sánchez-Hernández E, Teixeira A, Oliveira R, Cunha A, Martín-Ramos P Molecules 18-Jan-2024
PMCID:PMC10819938
doi:10.3390/molecules29020471
PMID:38257384
The Identification and Cytotoxic Evaluation of Nutmeg (Myristica fragrans Houtt.) and Its Substituents Khamnuan S, Phrutivorapongkul A, Pitchakarn P, Buacheen P, Karinchai J, Chittasupho C, Na Takuathung M, Theansungnoen T, Thongkhao K, Intharuksa A Foods 22-Nov-2023
PMCID:PMC10706638
doi:10.3390/foods12234211
PMID:38231602
Naturally Derived Malabaricone B as a Promising Bactericidal Candidate Targeting Multidrug-Resistant Staphylococcus aureus also Possess Synergistic Interactions with Clinical Antibiotics Sivadas N, Kaul G, Akhir A, Shukla M, Govind MG, Dan M, Radhakrishnan KV, Chopra S Antibiotics (Basel) 26-Sep-2023
PMCID:PMC10604362
doi:10.3390/antibiotics12101483
PMID:37887184
Acylphenols and Dimeric Acylphenols from the Genus Myristica: A Review of Their Phytochemistry and Pharmacology Othman MA, Sivasothy Y Plants (Basel) 09-Apr-2023
PMCID:PMC10143527
doi:10.3390/plants12081589
PMID:37111813
Do carbon stocks and floristic diversity of tropical homegardens vary along an elevational gradient and based on holding size in central Kerala, India? Kumar BM Agrofor Syst 07-Apr-2023
PMCID:PMC10081327
doi:10.1007/s10457-023-00821-7
PMID:37193256
Malabaricone C, a constituent of spice Myristica malabarica, exhibits anti-inflammatory effects via modulation of cellular redox Patwardhan RS, Kundu K, Purohit V, Kumar BK, Singh B, Thoh M, Undavia K, Bhilwade HN, Nayak SK, Sharma D, Sandur SK J Biosci 27-Mar-2023
PMCID:PMC10040911
doi:10.1007/s12038-023-00329-3
PMID:36971326
Advancements and future prospective of DNA barcodes in the herbal drug industry Mahima K, Sunil Kumar KN, Rakhesh KV, Rajeswaran PS, Sharma A, Sathishkumar R Front Pharmacol 21-Oct-2022
PMCID:PMC9635000
doi:10.3389/fphar.2022.947512
PMID:36339543
Ecological niche modelling as a tool to identify candidate indigenous chicken ecotypes of Tigray (Ethiopia) Gebru G, Belay G, Vallejo-Trujillo A, Dessie T, Gheyas A, Hanotte O Front Genet 30-Sep-2022
PMCID:PMC9561088
doi:10.3389/fgene.2022.968961
PMID:36246589
Recent Approaches towards Control of Fungal Diseases in Plants: An Updated Review El-Baky NA, Amara AA J Fungi (Basel) 25-Oct-2021
PMCID:PMC8621679
doi:10.3390/jof7110900
PMID:34829188
Different life stage, different risks: Thermal performance across the life cycle of Salmo trutta and Salmo salar in the face of climate change Kärcher O, Flörke M, Markovic D Ecol Evol 08-Jun-2021
PMCID:PMC8258189
doi:10.1002/ece3.7731
PMID:34257937
Application of Mass Spectrometry Imaging for Visualizing Food Components Yoshimura Y, Zaima N Foods 04-May-2020
PMCID:PMC7278736
doi:10.3390/foods9050575
PMID:32375379
Anti-Helicobacter pylori, Anti-Inflammatory, Cytotoxic, and Antioxidant Activities of Mace Extracts from Myristica fragrans Suthisamphat N, Dechayont B, Phuaklee P, Prajuabjinda O, Vilaichone RK, Itharat A, Mokmued K, Prommee N Evid Based Complement Alternat Med 29-Mar-2020
PMCID:PMC7146089
doi:10.1155/2020/7576818
PMID:32308716
Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing Basak M, Mahata T, Chakraborti S, Kumar P, Bhattacharya B, Bandyopadhyay SK, Das M, Stewart A, Saha S, Maity B Antioxid Redox Signal 04-Mar-2020
PMCID:PMC7071091
doi:10.1089/ars.2019.7781
PMID:31830804
Eco-Hydrological Footprint of a River Basin in Western Ghats Ramachandra TV, Vinay S, Bharath S, Shashishankar A Yale J Biol Med 21-Dec-2018
PMCID:PMC6302628
PMID:30588209

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
4-Hydroxybenzoic acid 135 Click to see C1=CC(=CC=C1C(=O)O)O 138.12 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / M-methoxybenzoic acids and derivatives
Vanillic Acid 8468 Click to see COC1=C(C=CC(=C1)C(=O)O)O 168.15 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
(2r)-1-(2-Hydroxy-4-methoxyphenyl)-3-(3,4-methylenedioxyphenyl)-propan-2-ol 162954302 Click to see 302.32 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
2-[3-(1,3-Benzodioxol-5-yl)-2-hydroxypropyl]-5-methoxyphenol 15460424 Click to see COC1=CC(=C(C=C1)CC(CC2=CC3=C(C=C2)OCO3)O)O 302.32 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Hentriacontane 12410 Click to see 436.80 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,7-epoxylignans
4-[(2S,3R,4S,5S)-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol 58507652 Click to see CC1C(C(OC1C2=CC(=C(C=C2)O)OC)C3=CC(=C(C=C3)O)OC)C 344.40 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
Aucubin 91458 Click to see C1=COC(C2C1C(C=C2CO)O)OC3C(C(C(C(O3)CO)O)O)O 346.33 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid 64945 Click to see 456.70 unknown via CMAUP database
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bR)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid 7163172 Click to see 456.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Stigmasterol 5280794 Click to see 412.70 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
Sucrose 5988 Click to see 342.30 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
GlyTouCan:G72414ZC 44420456 Click to see 504.40 unknown via CMAUP database
Stachyose 439531 Click to see 666.60 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones
1-(2,6-Dihydroxyphenyl)tetradecan-1-one 586401 Click to see 320.50 unknown https://doi.org/10.1021/JF050861X
9-(1,3-Benzodioxol-4-yl)-1-(2,6-dihydroxyphenyl)nonan-1-one 324063 Click to see 370.40 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
9-(1,3-Benzodioxol-5-yl)-1-(2,6-dihydroxyphenyl)-1-nonanone 13942402 Click to see C1OC2=C(O1)C=C(C=C2)CCCCCCCCC(=O)C3=C(C=CC=C3O)O 370.40 unknown https://doi.org/10.1021/JF050861X
https://doi.org/10.1016/S0031-9422(99)00489-6
Malabaricone A 324062 Click to see C1=CC=C(C=C1)CCCCCCCCC(=O)C2=C(C=CC=C2O)O 326.40 unknown https://doi.org/10.1021/JF050861X
https://doi.org/10.1016/S0031-9422(99)00489-6
Malabaricone B 163001 Click to see C1=CC(=C(C(=C1)O)C(=O)CCCCCCCCC2=CC=C(C=C2)O)O 342.40 unknown https://doi.org/10.1021/JF050861X
https://doi.org/10.1016/S0031-9422(99)00489-6
Malabaricone C 100313 Click to see 358.40 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
https://doi.org/10.1021/NP100872K
https://doi.org/10.1021/JF050861X
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / 6-aminopurines
Adenine 190 Click to see C1=NC2=NC=NC(=C2N1)N 135.13 unknown via CMAUP database
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
(2R,3R,4S,5S,6R)-2-[(E)-3-[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]prop-2-enoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 11027727 Click to see 520.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
[(2R,3R,4R,5R,6R)-2-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 6915840 Click to see 478.40 unknown via CMAUP database
[(2R,3R,4S,5R,6R)-2-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 5320625 Click to see 478.40 unknown via CMAUP database
[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 110062419 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
Calceolarioside A 5273566 Click to see C1=CC(=C(C=C1CCOC2C(C(C(C(O2)CO)OC(=O)C=CC3=CC(=C(C=C3)O)O)O)O)O)O 478.40 unknown via CMAUP database
Calceolarioside B 5273567 Click to see 478.40 unknown via CMAUP database
Hellicoside 5281778 Click to see C1=CC(=C(C=C1C=CC(=O)OC2C(OC(C(C2OC3C(C(C(C(O3)CO)O)O)O)O)OCC(C4=CC(=C(C=C4)O)O)O)CO)O)O 656.60 unknown via CMAUP database
Isoacteoside 6476333 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
Isomartynoside 91895373 Click to see 652.60 unknown via CMAUP database
Leucosceptoside A 10394343 Click to see 638.60 unknown via CMAUP database
Martynoside 5319292 Click to see 652.60 unknown via CMAUP database
Plantainoside B 9847922 Click to see 478.40 unknown via CMAUP database
Plantamajoside 5281788 Click to see C1=CC(=C(C=C1CCOC2C(C(C(C(O2)CO)OC(=O)C=CC3=CC(=C(C=C3)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 640.60 unknown via CMAUP database
Plantasioside 44423103 Click to see 476.40 unknown via CMAUP database
Scroside B 9831187 Click to see COC1=C(C=C(C=C1)CCOC2C(C(C(C(O2)COC(=O)C=CC3=CC(=C(C=C3)O)OC)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 668.60 unknown via CMAUP database
Verbascoside 5281800 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
Plantagoside 174157 Click to see 466.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Homoplantaginin 5318083 Click to see COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=C(C=C3)O)OC4C(C(C(C(O4)CO)O)O)O 462.40 unknown via CMAUP database
Plantaginin 5320623 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 4-O-methylisoflavones
Biochanin A 5280373 Click to see 284.26 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
biochanin A(1-) 25203224 Click to see 283.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 7-O-methylated isoflavonoids / 7-O-methylisoflavones
5-Hydroxy-4',7-dimethoxyisoflavone 5386259 Click to see 298.29 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
Prunetin 5281804 Click to see 284.26 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / 2-Hydroxy-dihydrochalcones
(2R)-2-hydroxy-1-(2-hydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)propan-1-one 42607724 Click to see 302.32 unknown https://doi.org/10.1016/S0031-9422(99)00489-6
Odoratol 442440 Click to see COC1=CC=C(C=C1)CC(C(=O)C2=C(C=C(C=C2)OC)O)O 302.32 unknown https://doi.org/10.1016/S0031-9422(99)00489-6

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