Fritillaria unibracteata

Details Top

Internal ID UUID64402656ed6e1091332092
Scientific name Fritillaria unibracteata
Authority Hsiao & K.C.Hsia
First published in Acta Phytotax. Sin. 15(2): 39 (1977)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among Chinese-speaking communities of eastern and southwestern China, especially in the areas around Zhejiang, Sichuan, and Yunnan, the dried bulbs of Fritillaria unibracteata—called Zhebei mu—have long been used in preparations meant to loosen phlegm, ease a tight cough, and soothe throat irritation. Historical and classical sources such as the Bencao Gangmu and later pharmacopoeial entries describe infusions or decoctions of the sliced bulb being taken for productive coughs, chronic bronchitis, and lung heat conditions. Bhutanese and Himalayan herbalists working with the broader Fritillaria group of “tulku” or “banglen” report similar practices using the bulb in teas or decoctions for coughs and to clear “lung fire,” with certain high-altitude forms treated as more potent, as documented by Ghimire and other regional ethnobotanists (Himalayan Ethnobotany, 2003). Ethnobotanical surveys of Tibetan communities in eastern Tibet and western Sichuan also record bulb tea and decoction preparations used to calm coughs and reduce thick mucus, particularly during winter respiratory illnesses, an association noted by Sherpa and Folsom (Ethnopharmacology of High Himalayas, 2016).

A practical, single-use preparation commonly recommended in modern Chinese practice is a simple bulb tea. Take about 6–9 g of sliced, dried Fritillaria unibracteata bulbs, add 300 mL of water, bring to a boil and simmer gently for 20–25 minutes, then strain and drink while warm. The tea is usually taken 1–3 times per day for several days as needed, and is suitable as a short-term remedy for a stubborn cough with thick phlegm. Many practitioners warn that stronger decoctions or longer simmering times can be too harsh, and they advise avoiding the bulb during pregnancy or lactation unless a qualified practitioner approves. Because the plant is considered mildly toxic in Chinese Materia Medica and should not be taken in excess, people on pharmaceutical antitussives or diuretics should seek professional guidance.

The respiratory effects of this bulb are plausibly linked to its well-established phytochemistry. Fritillaria species contain characteristic steroidal alkaloids such as imperialine, peimisine, verticinone, and verticine, which show antitussive, expectorant, and spasmolytic actions in experimental settings. These alkaloids are consistently reported for Fritillaria unibracteata and are believed to help relax smooth muscle and reduce excess secretions in the airways. Modern relevance remains strong: Zhebei mu is a staple in Chinese patent medicines and decoctions for cough and phlegm, and recent laboratory studies continue to profile the species’ alkaloid composition and bioactivity, supporting both contemporary clinical use and ongoing traditional practice.

General Uses Top

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Fragrance and cosmetics:
• Leaf essential oil analyzed by GC–MS has been documented to contain significant amounts of β-caryophyllene, caryophyllene oxide, and humulene, indicating potential as a fragrance material and a source of characteristic woody-spicy notes; however, no commercial fragrance or cosmetic products derived from F. unibracteata have been reported.

Industrial and craft applications:
• No documented industrial, timber, fiber, dye, gum, resin, starch, oil, adhesive, coating, biofuel, bioplastic, or fermentation-feedstock uses specific to F. unibracteata are available in the primary ethnobotanical or economic-botanical literature surveyed.

Food and beverages (non-medicinal):
• No culinary uses (food, beverage, or ingredient applications) have been recorded for this species.

Scientific/model-organism uses:
• The species is represented in DNA-based phylogenetic studies and in reference sequence resources; a reference chloroplast genome has been sequenced and deposited (GenBank accession NC_061474), supporting its use in comparative genomics and systematics.

Standards and regulation:
• No standards or regulatory frameworks specific to F. unibracteata as a commercial or industrial material are documented in the sources consulted.

Sustainability and sourcing:
• No documented sustainability assessments or sourcing frameworks specific to this taxon are available.

Synonyms Top

No known synonyms.

Common names Top

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Language Common/alternative name
Chinese 川贝母
Chinese 暗紫贝母
Chinese 冲松贝
Chinese 松贝
Chinese 暗紫貝母

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Fritillaria unibracteata var. longinectarea S.Y.Tang & S.C.Yueh Fl. Sichuanica 7: 60 (1991)
Fritillaria unibracteata var. unibracteata Unknown
Fritillaria unibracteata var. wabuensis (S.Y.Tang & S.C.Yueh) Z.D.Liu, Shu Wang & S.C.Chen Acta Bot. Yunnan. 31: 145 (2009)

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • Qinghai

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000768140
UNII U7T9NW5821
Tropicos 18406486
KEW urn:lsid:ipni.org:names:535351-1
The Plant List kew-306935
Open Tree Of Life 702580
NCBI Taxonomy 152095
IPNI 535351-1
iNaturalist 565537
GBIF 5300797
Freebase /m/0134lv3g
EOL 1088587
USDA GRIN 423618
Wikipedia Fritillaria_unibracteata
CMAUP NPO14849

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Genome-Wide Identification and Expression Profile Analysis of the Phenylalanine Ammonia-Lyase Gene Family in Hevea brasiliensis Liu H, He Q, Hu Y, Lu R, Wu S, Feng C, Yuan K, Wang Z Int J Mol Sci 06-May-2024
PMCID:PMC11084274
doi:10.3390/ijms25095052
PMID:38732270
Investigation the biological activities and the metabolite profiles of endophytic fungi isolated from Gundelia tournefortii L. Ebadi M, Ahmadi F, Tahmouresi H, Pazhang M, Mollaei S Sci Rep 25-Mar-2024
PMCID:PMC10963752
doi:10.1038/s41598-024-57222-8
PMID:38528041
Prediction of Potential Suitable Areas and Priority Protection for Cupressus gigantea on the Tibetan Plateau Zhang H, Wei Y, Yue J, Wang Z, Zou H, Ji X, Zhang S, Liu Z Plants (Basel) 20-Mar-2024
PMCID:PMC10974514
doi:10.3390/plants13060896
PMID:38592903
Traditional Tibetan medicine: therapeutic potential in lung diseases Li C, Li Y, Huang X, Li S, Sangji K, Gu R Front Pharmacol 18-Mar-2024
PMCID:PMC10986185
doi:10.3389/fphar.2024.1365911
PMID:38567353
Predicting the potential distribution of 12 threatened medicinal plants on the Qinghai‐Tibet Plateau, with a maximum entropy model Yang L, Zhu X, Song W, Shi X, Huang X Ecol Evol 15-Feb-2024
PMCID:PMC10867876
doi:10.1002/ece3.11042
PMID:38362168
Explorative study for the rapid detection of Fritillaria using gas chromatography-ion mobility spectrometry Dai Y, Liu S, Yang L, He Y, Guo X, Ma Y, Li S, Huang D Front Nutr 06-Feb-2024
PMCID:PMC10877000
doi:10.3389/fnut.2024.1361668
PMID:38379552
Ultrasound-assisted polysaccharide extraction from Fritillaria ussuriensis Maxim. and its structural characterization, antioxidant and immunological activity Jiang S, Wang Q, Wang Z, Borjigin G, Sun J, Zhao Y, Li Q, Shi X, faizan ali shah S, Wang X, Gan C, Wu Y, Song X, Li Q, Yang C Ultrason Sonochem 05-Feb-2024
PMCID:PMC10878995
doi:10.1016/j.ultsonch.2024.106800
PMID:38359575
Research on image recognition of three Fritillaria cirrhosa species based on deep learning Chen Y, Li Y, Zhang S Sci Rep 09-Nov-2023
PMCID:PMC10636039
doi:10.1038/s41598-023-46191-z
PMID:37945637
The power of magnesium: unlocking the potential for increased yield, quality, and stress tolerance of horticultural crops Ahmed N, Zhang B, Bozdar B, Chachar S, Rai M, Li J, Li Y, Hayat F, Chachar Z, Tu P Front Plant Sci 24-Oct-2023
PMCID:PMC10628537
doi:10.3389/fpls.2023.1285512
PMID:37941670
Effects of climate warming and human activities on the distribution patterns of Fritillaria unibracteata in eastern Qinghai-Tibetan Plateau Zhao D, Wang J, Dai W, Ye K, Chen J, Lai Q, Li H, Zhong B, Yu X Sci Rep 22-Sep-2023
PMCID:PMC10516939
doi:10.1038/s41598-023-42988-0
PMID:37737302
Current status of research on endophytes of traditional Tibetan medicinal plant and their metabolites Hu D, Long X, Luobu T, Wang Q 3 Biotech 11-Sep-2023
PMCID:PMC10495306
doi:10.1007/s13205-023-03720-x
PMID:37705864
Integrated metagenomics and metabolomics analysis reveals changes in the microbiome and metabolites in the rhizosphere soil of Fritillaria unibracteata Liu C, Yu J, Ying J, Zhang K, Hu Z, Liu Z, Chen S Front Plant Sci 04-Aug-2023
PMCID:PMC10436506
doi:10.3389/fpls.2023.1223720
PMID:37600181
Plants as the Extended Phenotype of Endophytes—The Actual Source of Bioactive Compounds Rutkowska N, Drożdżyński P, Ryngajłło M, Marchut-Mikołajczyk O Int J Mol Sci 13-Jun-2023
PMCID:PMC10298476
doi:10.3390/ijms241210096
PMID:37373241
Endophytic fungi mediates production of bioactive secondary metabolites via modulation of genes involved in key metabolic pathways and their contribution in different biotechnological sector Toppo P, Kagatay LL, Gurung A, Singla P, Chakraborty R, Roy S, Mathur P 3 Biotech 14-May-2023
PMCID:PMC10183385
doi:10.1007/s13205-023-03605-z
PMID:37197561
Authenticity and species identification of Fritillariae cirrhosae: a data fusion method combining electronic nose, electronic tongue, electronic eye and near infrared spectroscopy Gui XJ, Li H, Ma R, Tian LY, Hou FG, Li HY, Fan XH, Wang YL, Yao J, Shi JH, Zhang L, Li XL, Liu RX Front Chem 28-Apr-2023
PMCID:PMC10175593
doi:10.3389/fchem.2023.1179039
PMID:37188096

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Stearic Acid 5281 Click to see 284.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Glycerolipids / Triradylcglycerols / Triacylglycerols
Tristearin 11146 Click to see 891.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
(5R,19R)-11-ethyl-19-hydroxy-5-methyl-18-methylidene-9-oxa-11-azaheptacyclo[15.2.1.01,14.02,12.04,13.05,10.08,13]icosan-16-one 5321389 Click to see 355.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / 22,26-epiminocholestanes
(3S,5S,8S,9S,10R,13S,14S,17R)-17-[(1S)-1-[(2R,5S)-1,5-dimethylpiperidin-2-yl]ethyl]-3-hydroxy-10,13-dimethyl-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one 10693900 Click to see 429.70 unknown via CMAUP database
N-demethylpuqietinone 11304576 Click to see 415.70 unknown via CMAUP database
Puqietinone 44583920 Click to see 429.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Cerveratrum-type alkaloids
(1R,2S,6R,9S,11S,14S,15S,18S,20S,23R,24S)-20-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one 101687687 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)C 413.60 unknown via CMAUP database
(1R,2S,6S,9S,11S,14S,15S,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol 102063130 Click to see 431.70 unknown via CMAUP database
(1R,2S,6S,9S,11S,14S,15S,17S,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol 101297579 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O 431.70 unknown via CMAUP database
(1R,2S,6S,9S,11S,14S,15S,18S,20S,23R,24S)-10,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one 102063129 Click to see 429.60 unknown via CMAUP database
(1R,2S,6S,9S,11S,14S,15S,18S,20S,23R,24S)-20-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one 102062796 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)C 413.60 unknown via CMAUP database
(3b,5a,6a)-Cevane-3,6,20-triol 118701092 Click to see 431.70 unknown via CMAUP database
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-diol 3339044 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)C 415.70 unknown https://doi.org/10.1080/10286020.2011.619980
CID 14240939 14240939 Click to see 413.60 unknown https://doi.org/10.1080/10286020.2011.619980
Ebeiedine 101324888 Click to see 415.70 unknown via CMAUP database
Imperialine 442977 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)(C)O 429.60 unknown via CMAUP database
Isoverticine 21573744 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O 431.70 unknown via CMAUP database
Peimine 131900 Click to see 431.70 unknown via CMAUP database
Peiminine 5320446 Click to see 429.60 unknown via CMAUP database
Puqiedine 101400593 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)C 415.70 unknown https://doi.org/10.1080/10286020.2011.619980
Sinpeinine A 126149 Click to see 413.60 unknown via CMAUP database
Verticinone 167691 Click to see 429.60 unknown via CMAUP database
Zhebeirine 10597859 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)C 413.60 unknown https://doi.org/10.1080/10286020.2011.619980
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Jerveratrum-type alkaloids
(3S,3'R,3'aS,6'S,6aR,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,6,6a,6b,7,8,11,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-5-one 102119835 Click to see 427.60 unknown via CMAUP database
(3S,3'R,3'aS,6'S,6aR,6bS,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,6,6a,6b,7,8,11,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-5-one 21123947 Click to see 427.60 unknown via CMAUP database
(3S,3'R,4aS,6'S,6aR,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,6,6a,6b,7,8,11,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-5-one 71751476 Click to see 427.60 unknown via CMAUP database
3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,6,6a,6b,7,8,11,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-5-one 5320448 Click to see 427.60 unknown https://doi.org/10.1080/10286020.2011.619980
Peimisine 161294 Click to see CC1CC2C(C(C3(O2)CCC4C5CC(=O)C6CC(CCC6(C5CC4=C3C)C)O)C)NC1 427.60 unknown https://doi.org/10.1080/10286020.2011.619980
Songbaisine 197469 Click to see 427.60 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides
Puqietinonoside 21575476 Click to see CC1CCC(N(C1)C)C(C)C2CCC3C2(CCC4C3CC(=O)C5C4(CCC(C5)OC6C(C(C(C(O6)CO)O)O)O)C)C 591.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins
6-Hydroxycevan-2-yl hexopyranoside 127202 Click to see 577.80 unknown via CMAUP database
6-Oxocevan-2-yl hexopyranoside 127203 Click to see 575.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(3S,8R,9R,10S,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 636741 Click to see 414.70 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Purine nucleosides
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 6802 Click to see 283.24 unknown via CMAUP database
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 6021 Click to see 268.23 unknown via CMAUP database
Adenosine 60961 Click to see C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N 267.24 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Purine nucleosides / Purine 2-deoxyribonucleosides
Deoxyadenosine 13730 Click to see 251.24 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Pyrimidine nucleosides
Cytidine 6175 Click to see C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O 243.22 unknown via CMAUP database
Uridine 6029 Click to see 244.20 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Pyrimidine nucleosides / Pyrimidine 2-deoxyribonucleosides
Thymidine 5789 Click to see CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O 242.23 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
GlyTouCan:G20812UT 53301851 Click to see 342.30 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
Npc66700 9986231 Click to see 612.50 unknown via CMAUP database
> Organoheterocyclic compounds / Diazines / Pyrimidines and pyrimidine derivatives / Hydroxypyrimidines
5-methylpyrimidine-2,4-diol 5274265 Click to see 126.11 unknown via CMAUP database
> Organoheterocyclic compounds / Diazines / Pyrimidines and pyrimidine derivatives / Pyrimidones
Uracil 1174 Click to see 112.09 unknown via CMAUP database
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives
2-amino-3,7-dihydropurin-6-one 764 Click to see C1=NC2=C(N1)C(=O)N=C(N2)N 151.13 unknown via CMAUP database
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / 6-aminopurines
Adenine 190 Click to see C1=NC2=NC=NC(=C2N1)N 135.13 unknown via CMAUP database
> Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / Purinones / Hypoxanthines
CID 790 790 Click to see 136.11 unknown via CMAUP database
> Organoheterocyclic compounds / Pyrans / Pyranones and derivatives
Verrucosidin 6437365 Click to see CC1C2(C(O2)C(O1)(C)C=C(C)C=C(C)C3C(O3)(C)C4=C(C(=C(C(=O)O4)C)OC)C)C 416.50 unknown via CMAUP database

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