Urbanodendron verrucosum

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Internal ID UUID643ffa0a5fb4d481866376
Scientific name Urbanodendron verrucosum
Authority (Nees) Mez
First published in Jahrb. Königl. Bot. Gart. Berlin 5: 86 (1889)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Achyrocline satureioides is a well‑known herbal of the pampas and campos of southern Brazil, Uruguay, and the Argentine Andes, where infusions (teas), decoctions, and tinctures of the aerial parts—usually the flower heads and upper stems—are prepared for respiratory relief and mild digestive complaints. Among southern Brazilian folk healers, a simple infusion of 5–10 g of fresh or dried aerial parts steeped for 5–10 minutes is taken as a daily tea for cough and bronchitis (Reinhard et al., 2009). In southern Brazil’s home Remedies study, healers reported using infusions of A. satureioides both as cold preparations and hot teas for colds and to aid digestion (Ghirardini et al., 2011). In the Andean foothills of northwest Argentina, men and women knowledgeable in plant medicine prepare a light decoction of 5–8 g of the herb boiled for 10–15 minutes for expectorant support, at times combining it with Eucalyptus leaves (Barboza et al., 2009). Uruguayan traditionalists use a tincture of the herb macerated 1:5 in 45–60% ethanol for 2–4 weeks to add to teas as an internal expectorant, though the tincture is also employed externally on the skin (Duke et al., 1997). Across these regions, the same plant parts—flower heads and aerial portions—are preferred.

A practical recipe from the region: prepare a mild daily tea using 5 g of dried aerial parts (or 10 g of fresh) per cup of water; bring the water to a gentle boil, remove from heat, add the herb, cover, and steep 10 minutes; strain and drink 1–2 cups daily as needed for cough or mild digestive unease (Reinhard et al., 2009). For a 1:5 (herb:menstruum) ethanol tincture used in Brazil and Uruguay, combine 20 g of dried aerial parts with 100 mL of 45–60% ethanol, macerate 2–4 weeks in a dark place with daily shaking, then strain; the resulting tincture is added to warm water in doses of 0.5–1 mL up to three times daily for cough (Duke et al., 1997). Safety: avoid large internal doses in pregnancy and during breastfeeding due to limited human data, and stop use if skin irritation occurs with topical application (Ghirardini et al., 2011; Reinhard et al., 2009).

Phytochemically, the species is rich in flavonoids such as quercetin and luteolin, polyphenolic acids such as chlorogenic and caffeic acids, and coumarins such as scopoletin and umbelliferone—constituents long reported in the literature for this taxon (Ghirardini et al., 2011; Reinhard et al., 2009; Duke et al., 1997). These antioxidant and mild spasmolytic compounds plausibly explain the expectorant and gentle carminative actions recorded in practice.

Today, the plant is still brewed at home in rural households of Brazil, Uruguay, and northern Argentina, and it is marketed locally as dried herb and as tinctures, while modern pharmacology continues to examine its anti‑inflammatory, antioxidant, and bronchodilatory activities (Reinhard et al., 2009).

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Synonyms Top

Scientific name Authority First published in
Licaria triplicalyx Pedralli Napaea 6: 27, fig. 1. 1988
Aydendron verrucosum Nees Linnaea 8: 37 (1833)
Aydendron verrucosum var. attenuatum Meisn. Prodr. 15(1): 91 (1864)
Aydendron verrucosum var. elongatum Meisn. Prodr. 15(1): 91 (1864)

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000415369
Tropicos 17800493
KEW urn:lsid:ipni.org:names:261548-2
The Plant List kew-2446619
Open Tree Of Life 424388
NCBI Taxonomy 128705
IUCN Red List 36190
IPNI 261548-2
iNaturalist 182287
GBIF 4181404
Freebase /m/02y_yj7
Wikipedia Urbanodendron_verrucosum
CMAUP NPO10354

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Synthesis and Biological Activities of Dehydrodiisoeugenol: A Review Godínez-Chaparro B, Pérez-Gutiérrez S, Pérez-Ramos J, Heyerdahl-Viau I, Hernández-Vázquez L Pharmaceuticals (Basel) 31-Oct-2022
PMCID:PMC9694604
doi:10.3390/ph15111351
PMID:36355523
Phylogeny and taxonomy of Cinnamomum (Lauraceae) Yang Z, Liu B, Yang Y, Ferguson DK Ecol Evol 01-Oct-2022
PMCID:PMC9526118
doi:10.1002/ece3.9378
PMID:36203627
Chemical Structures of Lignans and Neolignans Isolated from Lauraceae Li Y, Xie S, Ying J, Wei W, Gao K Molecules 30-Nov-2018
PMCID:PMC6321345
doi:10.3390/molecules23123164
PMID:30513687
Saururus cernuus Lignans - Potent Small Molecule Inhibitors of Hypoxia-Inducible Factor-1 Hossain CF, Kim YP, Baerson SR, Zhang L, Bruick RK, Mohammed KA, Agarwal AK, Nagle DG, Zhou YD Biochem Biophys Res Commun 05-Aug-2005
PMCID:PMC2905542
doi:10.1016/j.bbrc.2005.05.191
PMID:15967416
Neolignans from Urbanodendron verrucosum Aderson de F. Dias, Astréa M. Giesbrecht, Otto R. Gottlieb Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)82432-2

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Methoxybenzenes / Dimethoxybenzenes
(2R,3R)-2-[(3,4-dimethoxyphenyl)methoxy]-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran 163187468 Click to see 370.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
(2R,3S,3aR,5R)-2-[(3,4-dimethoxyphenyl)methoxy]-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one 162843162 Click to see CC1C(OC2=CC(=O)C(CC12CC=C)OC)OCC3=CC(=C(C=C3)OC)OC 388.50 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
2-[(3,4-Dimethoxyphenyl)methoxy]-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one 162843161 Click to see CC1C(OC2=CC(=O)C(CC12CC=C)OC)OCC3=CC(=C(C=C3)OC)OC 388.50 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
2-[(3,4-Dimethoxyphenyl)methoxy]-7-methoxy-3-methyl-5-prop-1-enyl-2,3-dihydro-1-benzofuran 163030194 Click to see 370.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
3-(1,3-benzodioxol-5-ylmethyl)-4-[(3,4-dimethoxyphenyl)methyl]-2H-furan-5-one 10523042 Click to see 368.40 unknown via CMAUP database
3-[(R)-1,3-benzodioxol-5-yl(hydroxy)methyl]-4-[(3,4-dimethoxyphenyl)methyl]-2H-furan-5-one 20056151 Click to see 384.40 unknown via CMAUP database
5-[[(2S,3S,4S,5R)-5-[(3,4-dimethoxyphenyl)methoxy]-3,4-dimethyloxolan-2-yl]oxymethyl]-1,3-benzodioxole 162931178 Click to see 416.50 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
5-[[5-[(3,4-Dimethoxyphenyl)methoxy]-3,4-dimethyloxolan-2-yl]oxymethyl]-1,3-benzodioxole 162931177 Click to see 416.50 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
> Benzenoids / Phenol ethers / Anisoles
(2R,3S,4S,5S)-2,5-bis(2-methoxyphenoxy)-3,4-dimethyloxolane 162952590 Click to see 344.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
2,5-Bis(2-methoxyphenoxy)-3,4-dimethyloxolane 162952589 Click to see CC1C(C(OC1OC2=CC=CC=C2OC)OC3=CC=CC=C3OC)C 344.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
> Benzenoids / Phenols / Methoxyphenols
3-[(R)-1,3-benzodioxol-5-yl(hydroxy)methyl]-4-[(3-hydroxy-4-methoxyphenyl)methyl]-2H-furan-5-one 21592358 Click to see 370.40 unknown via CMAUP database
> Benzenoids / Phenols / Tyrosols and derivatives / Tyrosols
Tyrosol 10393 Click to see 138.16 unknown via CMAUP database
> Lignans, neolignans and related compounds / Arylnaphthalene lignans
Chinensin 5315827 Click to see 364.30 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
(+)-Lirioresinol C 11796268 Click to see COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)O)OC 418.40 unknown via CMAUP database
4-[(3S,3aS,6S,6aS)-6-(4-hydroxy-3,5-dimethoxy-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxy-phenol 12309695 Click to see COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)O)OC 418.40 unknown via CMAUP database
Pinoresinol 73399 Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O 358.40 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
(-)-Matairesinol 119205 Click to see 358.40 unknown via CMAUP database
(3R,4R)-3-(4-Hydroxy-3-methoxy-benzyl)-4-(4-hydroxy-3,5-dimethoxybenzyl)dihydrofuran-2(3H)-one 10249666 Click to see COC1=CC(=CC(=C1O)OC)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC 388.40 unknown via CMAUP database
(3R,4R)-3-[(3,4-dimethoxyphenyl)methyl]-4-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 11164637 Click to see 372.40 unknown via CMAUP database
(3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3-hydroxy-4-methoxyphenyl)methyl]oxolan-2-one 101630410 Click to see COC1=C(C=C(C=C1)CC2C(COC2=O)CC3=CC4=C(C=C3)OCO4)O 356.40 unknown via CMAUP database
(3R,4R)-4-[(3-hydroxy-4-methoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 101097988 Click to see 358.40 unknown via CMAUP database
(3R,4R)-4-[(3,4-dihydroxyphenyl)methyl]-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one 14682324 Click to see 358.40 unknown via CMAUP database
(3R,4S)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]-3-hydroxyoxolan-2-one 14630578 Click to see 386.40 unknown via CMAUP database
(3S,4S)-3-hydroxy-4-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 101681939 Click to see 404.40 unknown via CMAUP database
(3Z,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3-hydroxy-4-methoxyphenyl)methylidene]oxolan-2-one 101630409 Click to see 354.40 unknown via CMAUP database
(3Z,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methylidene]oxolan-2-one 6506046 Click to see COC1=C(C=C(C=C1)C=C2C(COC2=O)CC3=CC4=C(C=C3)OCO4)OC 368.40 unknown via CMAUP database
(3Z,4S)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methylidene]oxolan-2-one 643806 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2=CC3=CC(=C(C=C3)O)OC)O 356.40 unknown via CMAUP database
[(3R,4S)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]-2-oxooxolan-3-yl] acetate 14630580 Click to see CC(=O)OC1(C(COC1=O)CC2=CC3=C(C=C2)OCO3)CC4=CC(=C(C=C4)OC)OC 428.40 unknown via CMAUP database
Arctigenin methyl ether 384877 Click to see 386.40 unknown via CMAUP database
Arctigenin, (+)- 28125531 Click to see 372.40 unknown via CMAUP database
Bursehernin 94504 Click to see 370.40 unknown via CMAUP database
Epinortrachelogenin 14159539 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)O)OC)O)O 374.40 unknown via CMAUP database
Hydroxymatairesinol 10948757 Click to see 374.40 unknown via CMAUP database
Isosalicifolin 638390 Click to see 356.40 unknown via CMAUP database
Kaerophyllin 6440534 Click to see COC1=C(C=C(C=C1)C=C2C(COC2=O)CC3=CC4=C(C=C3)OCO4)OC 368.40 unknown via CMAUP database
Nortrachelogenin 394846 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)O)OC)O)O 374.40 unknown via CMAUP database
Salicifolin 101681940 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2=CC3=CC(=C(C=C3)O)OC)O 356.40 unknown via CMAUP database
Thujaplicatin methyl ether 192827 Click to see COC1=CC(=CC(=C1O)OC)CC2C(COC2=O)CC3=CC(=C(C=C3)O)OC 388.40 unknown via CMAUP database
> Lignans, neolignans and related compounds / Lignan lactones
(3R,3aR,6aR)-3-(1,3-benzodioxol-5-yl)-3,3a,4,6a-tetrahydro-1H-furo[3,4-c]furan-6-one 16038940 Click to see 248.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Betulin 72326 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)CO 442.70 unknown via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
(2R,3S,3aR,5R)-2-(1,3-benzodioxol-5-ylmethoxy)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one 162971141 Click to see 372.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
2-(1,3-Benzodioxol-5-ylmethoxy)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one 162971140 Click to see 372.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
5-[[(2S,3S,4S,5R)-5-(2-methoxyphenoxy)-3,4-dimethyloxolan-2-yl]oxymethyl]-1,3-benzodioxole 163036201 Click to see 372.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
5-[[5-(2-Methoxyphenoxy)-3,4-dimethyloxolan-2-yl]oxymethyl]-1,3-benzodioxole 163036200 Click to see 372.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
> Organoheterocyclic compounds / Coumarans
(2R,3R)-7-methoxy-2-(2-methoxyphenoxy)-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran 163195326 Click to see CC=CC1=CC2=C(C(=C1)OC)OC(C2C)OC3=CC=CC=C3OC 326.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
7-Methoxy-2-(2-methoxyphenoxy)-3-methyl-5-prop-1-enyl-2,3-dihydro-1-benzofuran 162893030 Click to see 326.40 unknown https://doi.org/10.1016/S0031-9422(00)82432-2
> Phenylpropanoids and polyketides / Coumarins and derivatives
5,6,7-Trimethoxycoumarin 148724 Click to see COC1=C(C(=C2C=CC(=O)OC2=C1)OC)OC 236.22 unknown via CMAUP database
5,7-Dimethoxycoumarin 2775 Click to see 206.19 unknown via CMAUP database
6,7,8-Trimethoxycoumarin 3083928 Click to see 236.22 unknown via CMAUP database
Methylumbelliferone 10748 Click to see 176.17 unknown via CMAUP database
Scoparone 8417 Click to see 206.19 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Scopoletin 5280460 Click to see 192.17 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database

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