(2R,3S,3aR,5R)-2-(1,3-benzodioxol-5-ylmethoxy)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one

Details

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Internal ID ee4a28a3-3082-4f73-b869-60cbf9ee1af9
Taxonomy Organoheterocyclic compounds > Benzodioxoles
IUPAC Name (2R,3S,3aR,5R)-2-(1,3-benzodioxol-5-ylmethoxy)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H24O6/c1-4-7-21-10-18(23-3)15(22)9-19(21)27-20(13(21)2)24-11-14-5-6-16-17(8-14)26-12-25-16/h4-6,8-9,13,18,20H,1,7,10-12H2,2-3H3/t13-,18-,20-,21-/m1/s1
InChI Key NFNHWTGOFDUITA-SRXWUYEGSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H24O6
Molecular Weight 372.40 g/mol
Exact Mass 372.15728848 g/mol
Topological Polar Surface Area (TPSA) 63.20 Ų
XlogP 3.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (2R,3S,3aR,5R)-2-(1,3-benzodioxol-5-ylmethoxy)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3,4,5-tetrahydro-1-benzofuran-6-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL240 Q12809 HERG 99.78% 89.76%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 98.18% 94.80%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.80% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.18% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.94% 96.77%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.42% 85.14%
CHEMBL2581 P07339 Cathepsin D 94.59% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.57% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 92.13% 93.40%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.51% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.46% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.27% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.16% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.34% 92.62%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.93% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.89% 97.14%
CHEMBL3492 P49721 Proteasome Macropain subunit 84.83% 90.24%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.33% 97.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.28% 89.00%
CHEMBL4208 P20618 Proteasome component C5 82.28% 90.00%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 81.97% 86.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.93% 99.17%
CHEMBL5957 P21589 5'-nucleotidase 81.41% 97.78%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.07% 82.38%
CHEMBL2413 P32246 C-C chemokine receptor type 1 80.60% 89.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Urbanodendron verrucosum

Cross-Links

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PubChem 162971141
LOTUS LTS0123874
wikiData Q105178570