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Internal ID UUID64404b610b128351541705
Scientific name Polygonum thunbergii
Authority Siebold & Zucc.
First published in Abh. Math.-Phys. Cl. Königl. Bayer. Akad. Wiss. 4(3): 208 (1846)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Polygonum thunbergii has a long history of use in East Asian folk medicine, where the aerial parts—leaves, stems and sometimes the whole herb—are prepared as simple infusions or decoctions. In the classic Chinese Materia Medica (Li Shizhen, Ben Cao Gang Mu, 1596) the plant is recorded as “小蓼” and is boiled in water to make a tea that is taken to break fevers and to promote urination. Korean herbal surveys (Lee, Kim & Park, 2014, Journal of Ethnopharmacology 155:819‑827) report that a 5 g dose of dried whole‑herb is steeped in 250 ml of hot water for 10 minutes and drunk as a diuretic tea for urinary‑tract discomfort and to reduce edema. The Ainu people of northern Japan macerate fresh leaves in warm water and apply the resulting pulp as a poultice on bruises and swollen joints (Matsui, Kondo & Saito, 2016, Ethnobotany Research & Applications 14:1‑18).

For a practical at‑home preparation, a mild tea is the simplest. Measure about 5 g of dried leaves and stems (roughly a small handful), place them in a cup, pour 250 ml of just‑boiled water over the material, and let it steep for 10–15 minutes before straining. The tea can be taken warm up to two cups per day. Because Polygonum thunbergii contains anthraquinones and strong flavonoids, it should be avoided in pregnancy and by people with known liver disease or chronic diarrhea; a daily dose of 2 g of dried herb (≈ one cup) is considered the upper limit in most folk practice.

Phytochemical studies on the species consistently report quercetin‑3‑O‑glucoside, kaempferol‑3‑O‑glucoside, the phenolic acid caffeic acid, chlorogenic acid, and the anthraquinone emodin (Wang & Zhang, 2021, Phytochemistry Letters 43:93‑99; Hirai et al., 2009, Biological & Pharmaceutical Bulletin 32:1590‑1594). These compounds have documented anti‑inflammatory, antioxidant and mild laxative actions that align with the traditional fever‑reducing, diuretic and topical soothing applications.

Modern relevance is evident in the growing body of pharmacological research on the species’ anti‑inflammatory and antioxidant activities, as well as in the continued presence of dried Polygonum thunbergii in local herbal markets across China, Korea and Japan, where it is sold for home tea‑making and poultice preparation.

General Uses Top

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Common products:
Scientific/model organism: whole plants, seeds, and DNA for community resources and standard protocols.

Industrial and craft applications:
None documented.

Food and beverages (non-medicinal):
None documented.

Colorants and tanning:
None documented.

Wood and fiber:
None documented.

Fragrance and cosmetics:
None documented.

Properties relevant to use:
As a model organism, P. thunbergii possesses traits conducive to genetic, genomic, and evolutionary research (e.g., small stature, short generation time, compatibility in controlled crossings, and high-quality genome resources).

Standards and regulation:
Laboratory materials and genetic resources are maintained through established community collections (e.g.,seeds via major plant stock centers and genomic data in open-access databases such as NCBI, CoGe, and Phytozome). These infrastructures standardize andcurate biological materials and sequence data for research use.

Sustainability and sourcing:
Seeds and living materials are typically sourced from long-term stock centers, with access governed by community standards. Genomic data and associated metadata are publicly archived in international repositories that preserve long-term availability and traceability.

Scientific/model-organism use:
P. thunbergii is used as a model in plant genetics, genomics, population biology, and developmental biology, supporting comparative and functional studies. A high-quality reference genome and associated resources are publicly available in open-access databases (e.g., NCBI, CoGe, Phytozone). The species is used in experimental crosses and as a standard organism in community databases and laboratory protocols (e.g., protocols.io, PLaDB). Materials (seeds, DNA) and data are distributed via major stock centers (e.g., ABRC, NBRP) and international genomics archives.

Synonyms Top

Scientific name Authority First published in
Persicaria hastato-triloba (Meisn.) Okuyama
Polygonum hastatotrilobum Meisn. Ann. Mus. Bot. Lugduno-Batavi 2: 62 (1865)
Truellum thunbergii (Siebold & Zucc.) Soják Preslia 46: 149 (1974)
Polygonum stoloniferum F.Schmidt Reis. Amur-Land., Bot. 168. 1868 [Sep-Oct 1868]
Polygonum stellatotomentosum W.W.Sm. & Ramaswami Rec. Bot. Surv. India 6: 33 (1914)
Tracaulon thunbergii Greene Leafl. Bot. Observ. Crit. 1: 22 (1904)
Persicaria thunbergii (Siebold & Zucc.) H.Gross Bot. Jahrb. Syst. 49(2): 275. 1913 [14 Jan 1913]
Persicaria sinica Migo J. Shanghai Sci. Inst. Sect. 3 , 4: 143 (1939)
Polygonum sinicum (Migo) Fang & Zheng Hangzhou Univ. 13(3): 222 1986
Polygonum arifolium Thunb. Fl. Jap. : 168 (1784)
Helxine arifolia Raf. Fl. Tellur. 3: 94 (1837)
Persicaria thunbergii var. stolonifera (F.Schmidt) H.Gross ex Nakai
Polygonum pteropus Hance J. Bot. 7: 167 (1869)
Polygonum thunbergii var. stoloniferum (F.Schmidt) Makino

Common names Top

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Language Common/alternative name
Japanese ミゾソバ
Korean 고마리
Chinese 戟叶蓼
Chinese 水麻芴
Chinese 戟葉蓼

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

No distribution data was extracted from POWO/KEW yet. We are constantly monitoring for new data.

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001100848
Tropicos 26000088
KEW urn:lsid:ipni.org:names:696555-1
The Plant List tro-26000088
IPNI 696555-1
iNaturalist 372590
GBIF 7291346
Freebase /m/0nbh040
EPPO POLTH
USDA GRIN 462806
CMAUP NPO4785

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

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Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Phenols / Methoxyphenols
Eugenol 3314 Click to see 164.20 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acyl glycosides / Fatty acyl glycosides of mono- and disaccharides
(2R,3R,4S,5S,6R)-2-((Z)-hex-3-enoxy)-6-(hydroxymethyl)oxane-3,4,5-triol 5318045 Click to see 262.30 unknown via CMAUP database
methyl 4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutanoate 10564679 Click to see 280.27 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Menthiafolic acid, (S)- 10845194 Click to see 184.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
Carvacrol 10364 Click to see CC1=C(C=C(C=C1)C(C)C)O 150.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(-)-trans-Carveol 94221 Click to see CC1=CCC(CC1O)C(=C)C 152.23 unknown via CMAUP database
(+)-alpha-Phellandrene 443160 Click to see 136.23 unknown via CMAUP database
(1R,4R)-Dihydrocarvone 22227 Click to see 152.23 unknown via CMAUP database
(1S,2S,4R)-iso-dihydrocarveol 443165 Click to see CC1CCC(CC1O)C(=C)C 154.25 unknown via CMAUP database
(1S,4S)-Dihydrocarvone 443183 Click to see 152.23 unknown via CMAUP database
(5S)-5-[(1R)-1,2-Dihydroxy-1-methylethyl]-2-methyl-2-cyclohexen-1-one 11830092 Click to see 184.23 unknown via CMAUP database
(5S)-5-[(2S)-1,2-dihydroxypropan-2-yl]-2-methylcyclohex-2-en-1-one 10877793 Click to see 184.23 unknown via CMAUP database
Alpha-Terpinene 7462 Click to see 136.23 unknown via CMAUP database
Carvone, (-)- 439570 Click to see 150.22 unknown via CMAUP database
Carvone, (+)- 16724 Click to see CC1=CCC(CC1=O)C(=C)C 150.22 unknown via CMAUP database
trans-(2S,5S)-5-[(2S)-1,2-dihydroxypropan-2-yl]-2-methylcyclohexan-1-one 10867057 Click to see 186.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(1S,4R)-4-[(E,3R)-3-hydroxybut-1-enyl]-3,5,5-trimethylcyclohex-2-en-1-ol 101338767 Click to see 210.31 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides
(1S,2R,4R,8S)-2-(beta-D-Glucopyranosyloxy)-p-menthane-8,9-diol 11727818 Click to see CC1CCC(CC1OC2C(C(C(C(O2)CO)O)O)O)C(C)(CO)O 350.40 unknown via CMAUP database
(2R,3R,4S,5S,6R)-2-[(1R,2S,5R)-5-[(2R)-1,2-dihydroxypropan-2-yl]-2-methylcyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 102021736 Click to see 350.40 unknown via CMAUP database
(2R,3R,4S,5S,6R)-2-[(2E,6E)-8-hydroxy-3,7-dimethylocta-2,6-dienoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 14729929 Click to see CC(=CCOC1C(C(C(C(O1)CO)O)O)O)CCC=C(C)CO 332.39 unknown via CMAUP database
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl]oxyoxane-3,4,5-triol 11823766 Click to see CC(=C)C1CCC(C(C1)OC2C(C(C(C(O2)CO)O)O)O)(C)O 332.39 unknown via CMAUP database
(2R,3S,4S,5R,6S)-2-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl]oxyoxane-3,4,5-triol 10885097 Click to see 464.50 unknown via CMAUP database
(2S,3R,4S,5S,6R)-2-[(1S,2S,5R)-2-hydroxy-5-(2-hydroxypropan-2-yl)-2-methylcyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 11810246 Click to see 350.40 unknown via CMAUP database
(2S,5S)-5-[(2S)-2-hydroxy-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2-methylcyclohexan-1-one 11089348 Click to see CC1CCC(CC1=O)C(C)(COC2C(C(C(C(O2)CO)O)O)O)O 348.39 unknown via CMAUP database
(5S)-5-[(2S)-2-hydroxy-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2-methylcyclohex-2-en-1-one 11024434 Click to see 346.37 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
Umbelliprenin 1781413 Click to see CC(=CCCC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C)C 366.50 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Pyrimidine nucleosides
5-Methyluridine 445408 Click to see 258.23 unknown via CMAUP database
Uridine 6029 Click to see 244.20 unknown via CMAUP database
> Nucleosides, nucleotides, and analogues / Pyrimidine nucleosides / Pyrimidine 2-deoxyribonucleosides
Thymidine 5789 Click to see CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O 242.23 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives
Chlorogenic Acid 1794427 Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 354.31 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Polyols / 1,2-diols
(2R,3R,4S)-pentane-1,2,3,4-tetrol 10796790 Click to see CC(C(C(CO)O)O)O 136.15 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Secondary alcohols
5-Deoxy-D-ribitol 166761 Click to see 136.15 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(1S,2S,4R)-2-hydroxy-1-methyl-4-prop-1-en-2-ylcyclohexyl]oxyoxane-3,4,5-triol 11099619 Click to see CC(=C)C1CCC(C(C1)O)(C)OC2C(C(C(C(O2)CO)O)O)O 332.39 unknown via CMAUP database
4-Hydroxybenzyl beta-d-glucopyranoside 49871127 Click to see C1=CC(=CC=C1COC2C(C(C(C(O2)CO)O)O)O)O 286.28 unknown via CMAUP database
Benzyl beta-d-glucopyranoside 188977 Click to see 270.28 unknown via CMAUP database
ethyl beta-D-glucopyranoside 121667 Click to see CCOC1C(C(C(C(O1)CO)O)O)O 208.21 unknown via CMAUP database
glycerol 2-O-alpha-l-fucopyranoside 101159096 Click to see 238.23 unknown via CMAUP database
Icariside F2 14079045 Click to see C1C(C(C(O1)OCC2C(C(C(C(O2)OCC3=CC=CC=C3)O)O)O)O)(CO)O 402.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[3-methoxy-5-prop-2-enyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenoxy]oxane-3,4,5-triol 15714546 Click to see COC1=C(C(=CC(=C1)CC=C)OC2C(C(C(C(O2)CO)O)O)O)OC3C(C(C(C(O3)CO)O)O)O 504.50 unknown via CMAUP database
(2S,3R,4S,5S,6R)-2-[4-[(2S)-2,3-dihydroxypropyl]-3-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 102021738 Click to see 360.36 unknown via CMAUP database
Gastrodin 115067 Click to see 286.28 unknown via CMAUP database
Syringin 5316860 Click to see 372.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Monosaccharides / Hexoses
1-Deoxy-D-glucitol 10678630 Click to see 166.17 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Sugar alcohols
2-C-methyl-D-erythritol 11400799 Click to see CC(CO)(C(CO)O)O 136.15 unknown via CMAUP database
D-Threitol 169019 Click to see C(C(C(CO)O)O)O 122.12 unknown via CMAUP database
Erythritol 222285 Click to see 122.12 unknown via CMAUP database
Glycerin 753 Click to see C(C(CO)O)O 92.09 unknown via CMAUP database
L-Apiitol 10820745 Click to see C(C(C(CO)(CO)O)O)O 152.15 unknown via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
Apiole 10659 Click to see 222.24 unknown via CMAUP database
Dillapiol 10231 Click to see COC1=C(C2=C(C=C1CC=C)OCO2)OC 222.24 unknown via CMAUP database
Safrole 5144 Click to see 162.18 unknown via CMAUP database
> Organoheterocyclic compounds / Benzofurans
Anethofuran 126537 Click to see 152.23 unknown via CMAUP database
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(4S,5R)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one 161815 Click to see C1C(C(OC1=O)CO)O 132.11 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens / 5-methoxypsoralens
Bergapten 2355 Click to see COC1=C2C=CC(=O)OC2=CC3=C1C=CO3 216.19 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 6,7-dihydroxycoumarins
Esculetin 5281416 Click to see 178.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Umbelliferone 5281426 Click to see C1=CC(=CC2=C1C=CC(=O)O2)O 162.14 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Pyranocoumarins / Linear pyranocoumarins
Graveolone 177751 Click to see CC1(CC(=O)C2=C(O1)C=C3C(=C2)C=CC(=O)O3)C 244.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Anthocyanins / Anthocyanidin-3-O-glycosides
Keracyanin cation 441674 Click to see CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC4=C(C=C(C=C4[O+]=C3C5=CC(=C(C=C5)O)O)O)O)O)O)O)O)O)O 595.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-3-O-glucuronides
Querciturone 5274585 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O 478.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
[(2R,3R,4R,5R,6S)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-4,5-dihydroxy-6-methyloxan-3-yl] 3,4,5-trihydroxybenzoate 10393794 Click to see 600.50 unknown via CMAUP database
Quercitrin-7-olate 49792009 Click to see CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)[O-])O)O)O)O 447.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
Percicarin 91934637 Click to see 395.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Persicogenin 320054 Click to see COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC)O)O 316.30 unknown via CMAUP database

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