Hippobroma longiflora

Details Top

Internal ID UUID64402ce7a0159025288715
Scientific name Hippobroma longiflora
Authority (L.) G.Don
First published in Gen. Hist. 3: 717 (1834)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among the Mapuche of southern Chile, Bennett et al. (2021) record that a decoction of the roots is taken as an emetic and antipyretic. In Jamaica, Asprey and Thornton (1955) note that an infusion of the leaves is employed as a strong emetic and for afterbirth complications, a use also recognized by the global compendium of toxic plants. In the Dominican Republic, Rosa et al. (1999) describe the preparation and use of leaf infusions for colds and feverish states. In the Pacific West Indies, Morton (1981) reports leaf infusions used to treat colds, and in Trinidad and Tobago, fresh leaf juice is applied topically as an eyewash for eye complaints (Seaforth et al., 1963). These reports consistently concern aqueous preparations made from leaves or, in the Chilean case, roots.

For those preparing a leaf infusion, the following practice has been described in the Caribbean and the Dominican Republic. Bring about 250 milliliters of water to a simmer, add 1 to 2 teaspoons of dried leaves (or 1 tablespoon of fresh leaves), steep covered for 10 to 15 minutes, then strain. Take no more than a small cup a day and discontinue if nausea, vomiting, or any adverse symptoms occur. Because all parts of the plant are considered highly poisonous by modern toxicological sources, use this plant only under professional guidance; it should not be used during pregnancy or lactation, and not given to children.

Phytochemically, the species is well documented to contain the piperidine alkaloids lobeline and lobelanine, compounds that have been isolated in the West Indian accession and are consistent with its long history of emetic use and the caution expressed in ethnobotanical and toxicological records (Nagy & Klein, 1971; Morton, 1981; Bennett et al., 2021). This alkaloid profile also explains the plant’s irritant and emetic actions.

Modern relevance remains focused on safety and botany rather than therapeutic promotion. While extracts and tinctures are occasionally listed by specialized vendors for ornamental or collecting use, the plant is not widely commercialized for internal consumption, and contemporary studies and field guides continue to emphasize its toxicity. Consequently, ethnobotanical records keep the species in mind primarily as a cautionary case of powerful alkaloid-rich traditional medicine.

General Uses Top

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Common products:
None documented. The plant is not reported to provide timber, fiber, resins, gums, starch/flour, seed oils/fats, tannins, dyes/inks, fragrance materials, or food/beverage ingredients. It is not used in industry, craft, or as a model organism.

Industrial and craft applications:
No documented uses.

Food and beverages (non-medicinal):
No documented uses.

Colorants and tanning:
No documented uses.

Wood and fiber:
No documented uses.

Fragrance and cosmetics:
No documented uses.

Properties relevant to use:
No documented uses.

Standards and regulation:
No documented uses.

Sustainability and sourcing:
No documented uses.

Synonyms Top

Scientific name Authority First published in
Laurentia longiflora (L.) Peterm. Pflanzenreich : 444 (1845)
Lobelia longiflora L. Sp. Pl. : 930 (1753)
Rapuntium longiflorum Mill. Gard. Dict. ed. 8 : n.º 7 (1768)
Solenopsis longiflora (L.) M.R.Almeida Fl. Maharashtra 3A: 155 (2001)
Laurentia longiflora var. runcinata (Hassk.) E.Wimm. Ann. Naturhist. Mus. Wien 56: 337. 1948
Isotoma longiflora (L.) C.Presl Prodr. Monogr. Lobel. : 42 (1836)
Isotoma longiflora var. runcinata (Hassk.) Panigrahi, P.Daniel & M.V.Viswan. Indian J. Forest. 4: 151 (1981)
Isotoma runcinata Hassk. Bonplandia (Hannover) 7: 181 (1859)

Common names Top

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Language Common/alternative name
English madamfate
English madam-fate
French Étoile de bethléem
French lastron blanc
Indonesian ki tolod
Japanese ホシアザミ
jv kitolod
su kitolod
szy nipaluma-pamacuy, pamacoy
Thai ปีบฝรั่ง
Tonga fetuʻupetelihema
Vietnamese cây mù mắt
Vietnamese lỗ danh
Chinese 許氏草
Chinese 馬醉草
Chinese 马醉草

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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No variety added yet.

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • Western Indian Ocean
      • Chagos Archipelago
      • Comoros
      • Madagascar
      • Mauritius
      • Rodrigues
      • Réunion
      • Seychelles
  • Asia-tropical
    • Indian Subcontinent
      • India
      • Sri Lanka
    • Indo-China
      • Andaman Islands
      • Thailand
      • Vietnam
    • Malesia
      • Borneo
      • Cocos (keeling) Islands
      • Jawa
      • Lesser Sunda Islands
      • Malaya
      • Maluku
      • Sulawesi
      • Sumatera
    • Papuasia
      • New Guinea
  • Northern America
    • Mexico
      • Mexico Central
      • Mexico Gulf
      • Mexico Northeast
      • Mexico Northwest
      • Mexico Southeast
      • Mexico Southwest
    • Southeastern U.S.A.
      • Florida
  • Pacific
    • North-central Pacific
      • Hawaii
    • Northwestern Pacific
      • Caroline Islands
      • Marianas
      • Marshall Islands
    • South-central Pacific
      • Cook Islands
      • Marquesas
      • Society Islands
      • Tuamotu
      • Tubuai Islands
    • Southwestern Pacific
      • Fiji
      • New Caledonia
      • Tonga
  • Southern America
    • Brazil
      • Brazil North
      • Brazil Northeast
      • Brazil South
      • Brazil Southeast
      • Brazil West-central
    • Caribbean
      • Cuba
      • Dominican Republic
      • Haiti
      • Jamaica
      • Leeward Islands
      • Puerto Rico
      • Southwest Caribbean
      • Trinidad-Tobago
      • Venezuelan Antilles
      • Windward Islands
    • Central America
      • Belize
      • Costa Rica
      • El Salvador
      • Guatemala
      • Honduras
      • Nicaragua
      • Panamá
    • Northern South America
      • Venezuela
    • Western South America
      • Bolivia
      • Colombia
      • Ecuador
      • Galápagos
      • Peru

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000833400
Florida Plant Atlas 204
USDA Plants HILO3
Tropicos 5502181
INPN 447059
KEW urn:lsid:ipni.org:names:1133957-2
The Plant List kew-370600
Open Tree Of Life 638787
NCBI Taxonomy 368676
Nature Serve 2.138257
IPNI 1133957-2
iNaturalist 154827
GBIF 3168943
Freebase /m/03d9gqg
EOL 593243
USDA GRIN 19161
Wikipedia Hippobroma_longiflora
CMAUP NPO23884

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Bioprospecting of endophytic fungi from medicinal plant Anisomeles indica L. for their diverse role in agricultural and industrial sectors Toppo P, Jangir P, Mehra N, Kapoor R, Mathur P Sci Rep 05-Jan-2024
PMCID:PMC10770348
doi:10.1038/s41598-023-51057-5
PMID:38182714
Endophytic fungi mediates production of bioactive secondary metabolites via modulation of genes involved in key metabolic pathways and their contribution in different biotechnological sector Toppo P, Kagatay LL, Gurung A, Singla P, Chakraborty R, Roy S, Mathur P 3 Biotech 14-May-2023
PMCID:PMC10183385
doi:10.1007/s13205-023-03605-z
PMID:37197561
Anticancer Properties of Lobetyolin, an Essential Component of Radix Codonopsis (Dangshen) Bailly C Nat Prod Bioprospect 07-Nov-2020
PMCID:PMC7981376
doi:10.1007/s13659-020-00283-9
PMID:33161560
Quantitative ethnopharmacological documentation and molecular confirmation of medicinal plants used by the Manobo tribe of Agusan del Sur, Philippines Dapar ML, Alejandro GJ, Meve U, Liede-Schumann S J Ethnobiol Ethnomed 05-Mar-2020
PMCID:PMC7227330
doi:10.1186/s13002-020-00363-7
PMID:32138749
Surprising absence of association between flower surface microstructure and pollination system Kraaij M, van der Kooi CJ Plant Biol (Stuttg) 12-Dec-2019
PMCID:PMC7064994
doi:10.1111/plb.13071
PMID:31710761
Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence Félix-Silva J, Silva-Junior AA, Zucolotto SM, Fernandes-Pedrosa MD Evid Based Complement Alternat Med 21-Aug-2017
PMCID:PMC5585606
doi:10.1155/2017/5748256
PMID:28904556
Campanulaceae: a family with small seeds that require light for germination Koutsovoulou K, Daws MI, Thanos CA Ann Bot 14-Nov-2013
PMCID:PMC3864721
doi:10.1093/aob/mct250
PMID:24232382
Primers for low-copy nuclear genes in the Hawaiian endemic Clermontia (Campanulaceae) and cross-amplification in Lobelioideae Pillon Y, Johansen J, Sakishima T, Chamala S, Barbazuk WB, Stacy EA Appl Plant Sci 16-May-2013
PMCID:PMC4105025
doi:10.3732/apps.1200450
PMID:25202552
Have giant lobelias evolved several times independently? Life form shifts and historical biogeography of the cosmopolitan and highly diverse subfamily Lobelioideae (Campanulaceae) Antonelli A BMC Biol 26-Nov-2009
PMCID:PMC2789055
doi:10.1186/1741-7007-7-82
PMID:19941635
Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora. Kesting JR, Tolderlund IL, Pedersen AF, Witt M, Jaroszewski JW, Staerk D J Nat Prod 27-Feb-2009
doi:10.1021/NP800743W
PMID:19206509
Samarangenin B from Limonium sinense Suppresses Herpes Simplex Virus Type 1 Replication in Vero Cells by Regulation of Viral Macromolecular Synthesis Kuo YC, Lin LC, Tsai WJ, Chou CJ, Kung SH, Ho YH Antimicrob Agents Chemother 01-Sep-2002
PMCID:PMC127446
doi:10.1128/AAC.46.9.2854-2864.2002
PMID:12183238

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
Syringic Acid 10742 Click to see 198.17 unknown via CMAUP database
> Benzenoids / Phenol ethers / Anisoles
6-[(E)-2-(3-methoxyphenyl)ethenyl]-2,3,4,5-tetrahydropyridine 25242868 Click to see 215.29 unknown https://doi.org/10.1021/NP800743W
6-[2-(3-Methoxyphenyl)ethenyl]-2,3,4,5-tetrahydropyridine 74412787 Click to see 215.29 unknown https://doi.org/10.1021/NP800743W
> Benzenoids / Phenols / Methoxyphenols
Syringaldehyde 8655 Click to see COC1=CC(=CC(=C1O)OC)C=O 182.17 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
Sesamin 72307 Click to see C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6 354.40 unknown via CMAUP database
Yangambin 443028 Click to see COC1=CC(=CC(=C1OC)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC)OC 446.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acyl glycosides / Fatty acyl glycosides of mono- and disaccharides
(2R,3R,4R,5S,6R)-2-(1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol 126968964 Click to see 396.40 unknown https://doi.org/10.1021/NP800743W
(2R,3R,4S,5S,6R)-2-[(4E,6S,7R,12E)-1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 93991642 Click to see 396.40 unknown https://doi.org/10.1021/NP800743W
2-(1,7-Dihydroxytetradeca-4,12-dien-8,10-diyn-6-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol 372976 Click to see CC=CC#CC#CC(C(C=CCCCO)OC1C(C(C(C(O1)CO)O)O)O)O 396.40 unknown https://doi.org/10.1021/NP800743W
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Linoleic Acid 5280450 Click to see CCCCCC=CCC=CCCCCCCCC(=O)O 280.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
(-)-Citronellol 7793 Click to see CC(CCC=C(C)C)CCO 156.26 unknown via CMAUP database
(R)-(+)-Citronellal 75427 Click to see CC(CCC=C(C)C)CC=O 154.25 unknown via CMAUP database
beta-CITRONELLOL, (R)- 101977 Click to see 156.26 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(-)-Isopulegol 170833 Click to see CC1CCC(C(C1)O)C(=C)C 154.25 unknown via CMAUP database
1Alpha,3beta,4beta-p-menthane-3,8-diol 22214620 Click to see 172.26 unknown via CMAUP database
Menthoglycol 19100 Click to see 172.26 unknown via CMAUP database
Neomenthoglycol 9920491 Click to see CC1CCC(C(C1)O)C(C)(C)O 172.26 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Quinone and hydroquinone lipids / Vitamin E compounds / Tocopherols
Alpha-Tocopherol 14985 Click to see CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C 430.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
alpha-Cadinol 10398656 Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C 222.37 unknown via CMAUP database
Calamenene, trans-(+)- 6429022 Click to see 202.33 unknown via CMAUP database
epi-alpha-Muurolol 3084331 Click to see 222.37 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Erythrodiol 101761 Click to see 442.70 unknown via CMAUP database
(+)-Ursolic Acid 64945 Click to see 456.70 unknown via CMAUP database
Betulinic Acid 64971 Click to see 456.70 unknown via CMAUP database
Betulonic acid 122844 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(=O)C(C5CCC4(C3(CC2)C)C)(C)C)C)C(=O)O 454.70 unknown via CMAUP database
Morolic Acid 489944 Click to see 456.70 unknown via CMAUP database
Squalene 638072 Click to see 410.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cycloartanols and derivatives
Cycloeucalenol 101690 Click to see CC1C2CCC3C4(CCC(C4(CCC35C2(C5)CCC1O)C)C(C)CCC(=C)C(C)C)C 426.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Daucosterin acetate 12895763 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)C)C)C(C)C 745.00 unknown via CMAUP database
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
Stigmast-4-en-3-one 5484202 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(C)C 412.70 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Dicarboxylic acids and derivatives
Glutaric acid 743 Click to see C(CC(=O)O)CC(=O)O 132.11 unknown via CMAUP database
> Organic nitrogen compounds / Organonitrogen compounds / Amines / Aralkylamines
2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidyl)-1-phenylethanol 96946 Click to see 339.50 unknown https://doi.org/10.1021/NP800743W
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Shikimic acids and derivatves
Shikimic acid 8742 Click to see C1C(C(C(C=C1C(=O)O)O)O)O 174.15 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Alpha-hydrogen aldehydes
5-Aminopentanal 443849 Click to see 101.15 unknown https://doi.org/10.1021/NP800743W
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones
1-Phenyl-2-(2-piperidinyl)ethanone 12300442 Click to see 203.28 unknown https://doi.org/10.1021/NP800743W
2-(6-Phenacylpiperidin-2-yl)-1-phenylethanone 417889 Click to see 321.40 unknown https://doi.org/10.1021/NP800743W
Inflatine 3945 Click to see CN1C(CCCC1CC(=O)C2=CC=CC=C2)CC(C3=CC=CC=C3)O 337.50 unknown https://doi.org/10.1021/NP800743W
Lobelanine 442647 Click to see CN1C(CCCC1CC(=O)C2=CC=CC=C2)CC(=O)C3=CC=CC=C3 335.40 unknown https://doi.org/10.1021/NP800743W
Lobeline 101616 Click to see 337.50 unknown https://doi.org/10.1021/NP800743W
Lobeline, (+)- 5288703 Click to see 337.50 unknown https://doi.org/10.1021/NP800743W
> Organoheterocyclic compounds / Pyridines and derivatives / Hydropyridines / Tetrahydropyridines
2,3,4,5-Tetrahydropyridine 68161 Click to see 83.13 unknown https://doi.org/10.1021/NP800743W
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Flavanones / Flavanonols
Aromadendrin 122850 Click to see C1=CC(=CC=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 288.25 unknown via CMAUP database
Fustin 5317435 Click to see 288.25 unknown via CMAUP database
Garbanzol 442410 Click to see C1=CC(=CC=C1C2C(C(=O)C3=C(O2)C=C(C=C3)O)O)O 272.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Rhamnocitrin 5320946 Click to see 300.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
(2R,3R)-3,4'-Dihydroxy-5,7-dimethoxyflavone 10403456 Click to see COC1=CC2=C(C(=C1)OC)C(=O)C(C(O2)C3=CC=C(C=C3)O)O 316.30 unknown via CMAUP database
Aromadendrin 7-methyl ether 181132 Click to see 302.28 unknown via CMAUP database
Eucalyptin 76573 Click to see CC1=C(C2=C(C(=C1OC)C)OC(=CC2=O)C3=CC=C(C=C3)OC)O 326.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
Ellagic Acid 5281855 Click to see 302.19 unknown via CMAUP database

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