Bergenia crassifolia

Details Top

Internal ID UUID64400cf189346990093957
Scientific name Bergenia crassifolia
Authority (L.) Fritsch
First published in Verh. Zool.-Bot. Ges. Wien 39: 587 (1889)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

In the West Siberian taiga and Altai, the thick, evergreen leaves of Bergenii are traditionally turned into a soothing tea. Villagers in Novosibirsk and Gorno‑Altaisk hot‑steep one generous leaf or a small handful of crushed leaves in a cup of boiling water for fifteen to twenty minutes, then sip it to calm sore throats, coughs, and bronchitis. Among the Buryats of Eastern Siberia and the Khalkh and Darkhad herders of Mongolia, both leaves and rhizomes are simmered as decoctions—about a teaspoon of chopped material to a cup of water, gently boiled for ten to twenty minutes—and used to reduce inflammation of the throat and gums and to treat diarrhea and dysentery. In Kazakhstan and Kyrgyzstan, a milder infusion of leaves is commonly taken as a digestive tea after meals, and in parts of China where Badan occurs, leaf infusions are drunk for “clear heat” in the throat and to support the urinary tract. These practices are recorded in Matskevich’s Medicinal Plants of Siberia and the Far East and in ethnobotanical surveys from Mongolia, Russia, and Central Asia.

One practical recipe is a simple but potent cold infusion used as a throat gargle and mild tea. Take one large fresh leaf (about 5–6 g) or four dried leaf fragments, crush them to release mucilage, add to 250 ml of just‑boiled water, and steep tightly covered for twenty to thirty minutes; strain and sip warm or use as a short gargle. For a 1:5 ethanol tincture that can be added to teas or used dropwise, macerate 20 g of powdered rhizome or leaf in 100 ml of 50% ethanol for two weeks, shaking daily, then strain; typical starting dose is 10–20 drops up to three times daily. Because the plant contains arbutin and related hydroquinone glycosides, people with kidney disease, salicylate sensitivity, or urinary stones should consult a clinician before use; avoid during pregnancy and breastfeeding due to limited data, and do not give concentrated ethanol tinctures to children.

Phytochemically, the leaves and rhizomes of Bergenii are richest in Bergenin, a C‑glycoside of bergenin; they also provide arbutin and methylarbutin, hydrolyzed to hydroquinone in the gut, along with gallotannins, ellagitannins, and flavonols such as quercetin and quercitrin. These compounds explain the plant’s astringent, anti‑inflammatory, antimicrobial, and urinary‑tract activity observed in traditional preparations.

Modern relevance: arbutin‑rich extracts from Bergenii are now marketed as standardized supplements and cosmetics, and contemporary research continues to explore bergenin’s gastroprotective and anti‑inflammatory actions, while herbalists in Siberia, Mongolia, and Central Asia still prepare leaf infusions and decoctions in home kitchens.

General Uses Top

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Common products:
Dried leaves yield Bergenin, a documented natural source of this compound used in dye and tanning applications.

Industrial and craft applications:
Leaves are used as a vegetable tanning material in leather processing. The hydrolyzable tannin extract imparts brown color and contributes to protein fixation. Hydrolyzable tannins (gallotannins) enable cross-linking of hide proteins; they are characterized by high hydrolysis yields (galloyl glucose residues) and are noted for high reactivity toward iron salts to generate dark brown iron–tannate complexes.

Colorants and tanning:
Leaves or leaf extracts provide natural brown dyes for protein fibers (wool, silk) via metal-mordant systems (typically iron(II) sulfate) that yield fast browns to near-blacks on wool. The same extracts are used in vegetable leather tanning to achieve brown shades; hydrolyzable tannins offer strong binding to collagen and good color development with metal salts.

Properties relevant to use:
Hydrolyzable tannin profile (gallotannins/ellagitannins) supports rapid tanning kinetics and deep brown hues. Bergenin (C14H18O9) acts as a galloyl glucose unit useful in color formation and adhesion; the gallotannin structure provides strong binding to protein fibers and metal mordants. Extracts are water-soluble, enabling straightforward dye-bath and tanning-bath preparation.

Sustainability and sourcing:
Bergenia crassifolia is native to alpine and subalpine Central and Eastern Asia and is widely cultivated as an ornamental, facilitating leaf harvesting as a byproduct or from managed stands. Sustainable harvest involves leaf collection post-flowering, avoidance of overharvesting from wild populations, and implementation of regrowth periods; specific regulations vary by region.

Synonyms Top

Scientific name Authority First published in
Megasea media Haw. Saxifrag. Enum. 1: 7 (1821)
Megasea crassifolia Haw. Saxifrag. Enum. 1: 6 (1821)
Megasea cordifolia Haw. Saxifrag. Enum. 1: 7 (1821)
Piarophyla cordifolia Raf. Fl. Tellur. 2: 68 (1837)
Piarophyla elliptica Raf. Fl. Tellur. 2: 68 (1837)
Bergenia biflora Moench Methodus (Moench) 664 (1794). [4 May 1794]
Bergenia biflora var. hawortiana (Ser.) Engl. Bot. Zeitung (Berlin) 26: 840 1868
Bergenia bifolia Moench Methodus : 664 (1794)
Bergenia cordifolia Sternb. Revis. Saxifrag. , Suppl. 2: 2 (1831)
Bergenia coreana Nakai Bot. Mag. (Tokyo) 28: 304. 1914
Bergenia crassifolia var. cordifolia (Haw.) Boriss. Trudy Bot. Inst. Acad. Nauk S.S.S.R., V, Rastitel'n. Syr'e 4: 315 1956
Bergenia media Engl. Nat. Pflanzenfam. 3(2a): 51 (1890)
Geryonia crassifolia Schrank ex Hoppe Flora 1: 229 (1818)
Bergenia crassifolia var. sajanensis Stepanov Fl. N.E. W. Sayan : 126 (2006)
Saxifraga crassifolia L. Sp. Pl. : 401 (1753)
Saxifraga cordifolia Haw. Misc. Nat. : 157 (1803)
Saxifraga crassifolia var. obovata Ser. Prodr. 4: 37 1830
Saxifraga crassifolia var. pauciflora Ser. Prodr. 4: 37 1830

Common names Top

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Language Common/alternative name
English siberian-tea
Arabic برغنية سميكة الأوراق
Azerbaijani qalınyarpaq bergeniya
Belarusian бадан таўсталісты
bxr Бадаан
Czech bergenie tučnolistá
Welsh clustiau eliffant
Estonian kaheleheline bergeenia
Persian گل برگنیا
Finnish soikkovuorenkilpi
Croatian slonovo uho (kamenikovke)
Upper Sorbian tołstołopjenata bergenija
Kazakh Шағыршай
Kazakh Етжапырақ бадан
Lithuanian storalapė bergenija
Latvian biezlapu bergēnija
Russian Бадан толстолистный
Russian Камнеломка толстолистная
Russian Бадан сердцелистный
Slovak bergénia tučnolistá
tt Каты яфраклы чагыр
Chinese 厚叶岩白菜
Chinese 厚叶岩白釋_
Chinese 厚叶梅
Chinese 青海白菜

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Bergenia crassifolia var. pacifica (Kom.) Kom. ex Nekr. Fl. Aziatik Ross. 2: 15. 1917 (1917)
Bergenia crassifolia var. crassifolia Unknown

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • Xinjiang
    • Eastern Asia
      • Korea
    • Middle Asia
      • Kazakhstan
    • Mongolia
      • Mongolia
    • Russian Far East
      • Amur
      • Khabarovsk
      • Primorye
    • Siberia
      • Altay
      • Buryatiya
      • Chita
      • Irkutsk
      • Krasnoyarsk
      • Tuva
      • West Siberia
      • Yakutskiya
  • Europe
    • Eastern Europe
      • South European Russia
    • Middle Europe
      • Czechoslovakia
      • Germany
      • Switzerland
    • Northern Europe
      • Great Britain
      • Ireland
    • Southeastern Europe
      • Bulgaria
      • Italy
      • Yugoslavia
    • Southwestern Europe
      • France
  • Southern America
    • Southern South America
      • Juan Fernández Islands

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000564227
UNII PU9M538O5N
USDA Plants BECR3
Tropicos 29100119
INPN 85779
Flora of Italy 8413
KEW urn:lsid:ipni.org:names:790361-1
The Plant List kew-2674805
Missouri Botanical Garden 286869
Open Tree Of Life 756735
Observations.org 115506
NCBI Taxonomy 29762
NBN Atlas NBNSYS0000013952
IPNI 790361-1
iNaturalist 127228
GBIF 5567694
Freebase /m/0dgnn5c
EPPO BENCR
EOL 2886991
Elurikkus 209262
USDA GRIN 404437
Wikipedia Bergenia_crassifolia
CMAUP NPO6749
Plantarium 6418

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition Todorova V, Ivanova S, Chakarov D, Kraev K, Ivanov K Nutrients 02-May-2024
PMCID:PMC11085066
doi:10.3390/nu16091382
PMID:38732627
Unravelling and reconstructing the biosynthetic pathway of bergenin Yan R, Xie B, Xie K, Liu Q, Sui S, Wang S, Chen D, Liu J, Chen R, Dai J, Yang L Nat Commun 26-Apr-2024
PMCID:PMC11053098
doi:10.1038/s41467-024-47502-2
PMID:38670975
Nose of dog, eye of elk, and wolf’s liver: exploring the interconnectedness of Indigenous health and foraging among the Dukha reindeer herders of Mongolia Hatcherson J Int J Circumpolar Health 18-Apr-2024
PMCID:PMC11028006
doi:10.1080/22423982.2024.2343454
PMID:38634711
TCM and related active compounds in the treatment of gout: the regulation of signaling pathway and urate transporter Sun X, Yang L, Sun H, Sun Y, Wei S, Han Y, Wang W, Kong L, Wang X Front Pharmacol 29-Nov-2023
PMCID:PMC10716793
doi:10.3389/fphar.2023.1275974
PMID:38094893
Contemporary strategies and approaches for characterizing composition and enhancing biofilm penetration targeting bacterial extracellular polymeric substances Lu L, Zhao Y, Li M, Wang X, Zhu J, Liao L, Wang J J Pharm Anal 29-Nov-2023
PMCID:PMC11022105
doi:10.1016/j.jpha.2023.11.013
PMID:38634060
Plant Extracts as Skin Care and Therapeutic Agents Michalak M Int J Mol Sci 22-Oct-2023
PMCID:PMC10607442
doi:10.3390/ijms242015444
PMID:37895122
Morphometric Characteristics and Genetic Issr Marker Variability in Rhodiola rosea L. (Crassulaceae) in Different Ecological and Geographic Conditions in the Altai Republic Dorogina OV, Kuban IN, Achimova AA, Williams N, Lashchinskiy NN, Zhmud EV Int J Mol Sci 16-Oct-2023
PMCID:PMC10607822
doi:10.3390/ijms242015224
PMID:37894905
The most polyphagous insect herbivore? Host plant associations of the Meadow spittlebug, Philaenus spumarius (L.) Thompson V, Harkin C, Stewart AJ PLoS One 04-Oct-2023
PMCID:PMC10602594
doi:10.1371/journal.pone.0291734
PMID:37792900
Regulation of autophagy by natural polyphenols in the treatment of diabetic kidney disease: therapeutic potential and mechanism Liu T, Jin Q, Yang L, Mao H, Ma F, Wang Y, Li P, Zhan Y Front Endocrinol (Lausanne) 10-Aug-2023
PMCID:PMC10448531
doi:10.3389/fendo.2023.1142276
PMID:37635982
The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity Semwal P, Rauf A, Olatunde A, Singh P, Zaky MY, Islam MM, Khalil AA, Aljohani AS, Al Abdulmonem W, Ribaudo G Nat Prod Bioprospect 12-May-2023
PMCID:PMC10176313
doi:10.1007/s13659-023-00380-5
PMID:37171512
New Data on Native and Alien Vascular Flora of Sicily (Italy): New Findings and Updates Cambria S, Azzaro D, Caldarella O, Aleo M, Bazan G, Guarino R, Torre G, Cristaudo AE, Ilardi V, La Rosa A, Laface VL, Luchino F, Mascia F, Minissale P, Sciandrello S, Tosetto L, Tavilla G Plants (Basel) 23-Apr-2023
PMCID:PMC10181230
doi:10.3390/plants12091743
PMID:37176800
Pectin-like polysaccharide extracted from leaves Crataeva tapia promotes antioxidant, immunomodulatory and emulsifiers applied in therapeutic formulations da Paz Leôncio Alves S, Jacob IT, Arruda MD, da Silva AR, de Sousa GF, de Souza GA, de Lima MD, de Souza IA, de Melo CM, da Cruz Filho IJ, do Nascimento Santos DK 3 Biotech 09-Mar-2023
PMCID:PMC9998804
doi:10.1007/s13205-023-03509-y
PMID:36909979
Chemistry and Pharmacology of Bergenin or Its Derivatives: A Promising Molecule Salimo ZM, Yakubu MN, da Silva EL, de Almeida AC, Chaves YO, Costa EV, da Silva FM, Tavares JF, Monteiro WM, de Melo GC, Koolen HH Biomolecules 21-Feb-2023
PMCID:PMC10046151
doi:10.3390/biom13030403
PMID:36979338
Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent Nahar L, Al-Groshi A, Kumar A, Sarker SD Molecules 11-Dec-2022
PMCID:PMC9787540
doi:10.3390/molecules27248786
PMID:36557918
New insight into the management of renal excretion and hyperuricemia: Potential therapeutic strategies with natural bioactive compounds Yang B, Xin M, Liang S, Xu X, Cai T, Dong L, Wang C, Wang M, Cui Y, Song X, Sun J, Sun W Front Pharmacol 22-Nov-2022
PMCID:PMC9723165
doi:10.3389/fphar.2022.1026246
PMID:36483739

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives
Phenylethyl Alcohol 6054 Click to see C1=CC=C(C=C1)CCO 122.16 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
(2R,3S,4S,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one 24982180 Click to see 328.27 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters / Fatty acid methyl esters
Methyl petroselinate 5362717 Click to see 296.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
p-Mentha-1,3,8-triene 176983 Click to see CC1=CC=C(CC1)C(=C)C 134.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
alpha-Cadinol 10398656 Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C 222.37 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
Icariside F2 14079045 Click to see C1C(C(C(O1)OCC2C(C(C(C(O2)OCC3=CC=CC=C3)O)O)O)O)(CO)O 402.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
(2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol 7576924 Click to see 272.25 unknown via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
Apiole 10659 Click to see 222.24 unknown via CMAUP database
Myristicin 4276 Click to see 192.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens
Isoimperatorin 68081 Click to see 270.28 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens / 8-methoxypsoralens
Cnidilin 821449 Click to see 300.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol 5280863 Click to see 286.24 unknown https://doi.org/10.1016/0305-1978(86)90088-8
Quercetin 5280343 Click to see 302.23 unknown https://doi.org/10.1016/0305-1978(86)90088-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxychromen-4-one 51402807 Click to see 464.40 unknown https://doi.org/10.1016/0305-1978(86)90088-8
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3-dihydrochromen-4-one 5317364 Click to see 436.40 unknown https://doi.org/10.1016/0305-1978(86)90088-8
5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(3,4,5-trihydroxyoxan-2-yl)oxychromen-4-one 14749097 Click to see 418.30 unknown https://doi.org/10.1016/0305-1978(86)90088-8
acs.jmedchem.1c00409_ST.657 5878729 Click to see 434.30 unknown https://doi.org/10.1016/0305-1978(86)90088-8
Astragalin 5282102 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown via CMAUP database
Hyperoside 5281643 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 464.40 unknown https://doi.org/10.1016/0305-1978(86)90088-8
Kaempferol 3-xylosylglucoside 131752667 Click to see 580.50 unknown https://doi.org/10.1016/0305-1978(86)90088-8
Rutin 5280805 Click to see 610.50 unknown https://doi.org/10.1016/0305-1978(86)90088-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
6''-Acetylapiin 10531745 Click to see 606.50 unknown via CMAUP database
Apigenin 7-O-glucoside 5280704 Click to see 432.40 unknown via CMAUP database
Apiin 5280746 Click to see 564.50 unknown via CMAUP database
Diosmetin 7-O-beta-D-glucoside 11016019 Click to see 462.40 unknown via CMAUP database
Luteolin 7-O-(2-(beta-D-apiofuranosyl)-beta-D-glucopyranoside) 101248035 Click to see 580.50 unknown via CMAUP database
Malonylapiin 5280803 Click to see 650.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 4-O-methylated flavonoids
Diosmetin 5281612 Click to see COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O 300.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / Isoflav-2-enes / Isoflavones
Genistein 5280961 Click to see 270.24 unknown via CMAUP database

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