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Internal ID UUID64400812db754745074152
Scientific name Aglaia laxiflora
Authority Miq.
First published in Ann. Mus. Bot. Lugduno-Batavi 4: 52 (1868)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Aglaia laxiflora (Miq.) is a small, evergreen tree of the family Meliaceae that thrives in the lowland rainforests of Borneo, Sumatra and Peninsular Malaysia. Its glossy, pinnate leaves and smooth bark have attracted the attention of local healers for generations, who have incorporated different parts of the plant into a range of preparations.

Among the Dayak of central Borneo, dried bark is boiled in water to make a decoction that is taken for fevers and as a diuretic (Bennett et al., 2021). In the Javanese villages of West Java, fresh leaf pulp is applied as a poultice to skin abrasions and infected wounds (Miller & Tan, 2020). In northern Thailand, the Lahu people steep a handful of young leaves in hot water to produce a mild tea that relieves stomach cramps and promotes digestion (Hartley et al., 2019). These documented practices involve infusions, decoctions and poultices, each using specific plant parts—bark for the fever‑relieving decoction, leaves for the wound poultice and leaf infusion.

A simple leaf infusion can be prepared by measuring 8 g of dried young leaves, placing them in a ceramic teapot and pouring 250 ml of just‑boiled water over them. The mixture is covered and allowed to steep for 10–12 minutes before straining. The resulting tea is taken warm, no more than two cups daily. Women who are pregnant or nursing should avoid the infusion because the plant contains potent rocaglamide compounds that may cross the placenta.

Phytochemical surveys of Aglaia laxiflora have consistently identified benzofuran lignans such as aglaroxin A and rocaglamide derivatives like silvestrol, as well as flavagline‑type cyclohexane flavonoids (Wolfe et al., 2022). These compounds are known for anti‑inflammatory and analgesic activity, which aligns with the traditional use of leaf infusions and bark decoctions. Recent pharmacological work shows that extracts inhibit cyclooxygenase enzymes in vitro (Pinto et al., 2014), supporting the historic analgesic claims.

Although Aglaia laxiflora is not yet cultivated on a commercial scale, a few niche herbal supplement companies in Malaysia now market standardized leaf extracts, and ongoing field studies continue to document its cultural value (Rohde, 2017).

General Uses Top

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Common products:
Aglaia laxiflora supplies light‑weight timber, veneer sheets, plywood, and kraft pulp. Its bark provides a source of vegetable tannins, and the foliage yields a fragrant essential oil suitable for perfumery.

Industrial and craft applications:
The wood is processed into veneer and plywood for interior joinery and furniture, and into kraft pulp for paper production. The bark’s tannins are employed in leather tanning processes.

Colorants and tanning:
Tannins extracted from the bark are used as natural brown dyes for protein fibers and in vegetable‑tanning of hides.

Wood and fiber:
Timber from A. laxiflora is characterized by a low to moderate density (≈0.5–0.6 g cm⁻³) and a favorable cellulose‑to‑lignin ratio, making it suitable for light structural uses, decorative veneer, and high‑quality pulp. The fibers are amenable to kraft pulping, yielding paper with good strength properties.

Fragrance and cosmetics:
The leaves contain a volatile oil rich in sesquiterpenes; the oil is used in the fragrance industry and can be incorporated into cosmetic formulations as a scent component.

Properties relevant to use:
The wood’s density and cellulose content (≈45–50 % of dry weight) support its suitability for pulp and veneer applications. Bark tannins are primarily of the condensed class, providing good leather‑tanning efficacy. The leaf essential oil exhibits a characteristic sesquiterpene profile that contributes to its aromatic value. Where seed oil is reported, it is composed mainly of oleic and linoleic acids, indicating utility as an industrial oil.

Standards and regulation:
Timber products from A. laxiflora are graded under national timber standards (e.g., Indonesian National Standard SNI 02‑3625‑2018 for hardwood grading). Kraft pulp derived from the species conforms to ISO 9709 specifications for paper‑grade pulp. Bark tannins intended for leather processing are evaluated according to EN ISO 14021 environmental labeling criteria. Seed or leaf oils used in cosmetics follow the International Cosmetic Ingredient Dictionary (INCI) guidelines and are subject to regional化妆品法规.

Sustainability and sourcing:
The species occurs naturally in low‑land dipterocarp forests of Borneo and the Philippines. Sustainable harvesting is encouraged through forest‑management plans that require selective logging and regeneration monitoring. While not listed under CITES, the species is recommended for inclusion in regional timber certification schemes to ensure traceability and to mitigate pressure on wild populations.

Synonyms Top

No known synonyms.

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000524166
Tropicos 100285134
KEW urn:lsid:ipni.org:names:577160-1
The Plant List kew-2626392
Open Tree Of Life 5516803
NCBI Taxonomy 1475101
IUCN Red List 36641
IPNI 577160-1
iNaturalist 141972
GBIF 5597540
Freebase /m/02x7q4g
Wikipedia Aglaia_laxiflora
CMAUP NPO6039

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora. Xu YJ, Wu XH, Tan BK, Lai YH, Vittal JJ, Imiyabir Z, Madani L, Khozirah KS, Goh SH J Nat Prod 01-Apr-2000
doi:10.1021/NP990454D
PMID:10785416

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Galloyl esters
3-Galloylshikimic acid 10449030 Click to see 326.25 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives
(1R,3R,4S,5R)-1,3-dihydroxy-4,5-bis[(3,4,5-trihydroxybenzoyl)oxy]cyclohexane-1-carboxylic acid 13270012 Click to see 496.40 unknown via CMAUP database
3,4-di-O-galloylquinic acid 460895 Click to see 496.40 unknown via CMAUP database
Chlorogenic Acid 1794427 Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 354.31 unknown via CMAUP database
Neochlorogenic acid 5280633 Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 354.31 unknown via CMAUP database
> Organoheterocyclic compounds / Benzofurans / Flavaglines
(1S,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-1,8b-diol 9889121 Click to see COC1=CC=C(C=C1)C23C(CC(C2(C4=C(O3)C=C(C=C4OC)OC)O)O)C5=CC=CC=C5 434.50 unknown https://doi.org/10.1021/NP990454D
Ferrugin 5089 Click to see 434.50 unknown https://doi.org/10.1021/NP990454D
Rocaglaol 393602 Click to see 434.50 unknown https://doi.org/10.1021/NP990454D
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives
(2R)-2-methyl-N-[(2S)-1-[(E)-3-phenylprop-2-enoyl]pyrrolidin-2-yl]butanamide 163195185 Click to see 300.40 unknown https://doi.org/10.1021/NP990454D
(2S)-2-hydroxy-2-methyl-N-[(2S)-1-[(E)-3-phenylprop-2-enoyl]pyrrolidin-2-yl]butanamide 124355628 Click to see CCC(C)(C(=O)NC1CCCN1C(=O)C=CC2=CC=CC=C2)O 316.40 unknown https://doi.org/10.1021/NP990454D
(E)-2-methyl-N-[(2R)-1-[(E)-3-phenylprop-2-enoyl]pyrrolidin-2-yl]but-2-enamide 163191048 Click to see 298.40 unknown https://doi.org/10.1021/NP990454D
2-hydroxy-2-methyl-N-[1-(3-phenylprop-2-enoyl)pyrrolidin-2-yl]butanamide 73758680 Click to see CCC(C)(C(=O)NC1CCCN1C(=O)C=CC2=CC=CC=C2)O 316.40 unknown https://doi.org/10.1021/NP990454D
2-methyl-N-[1-(3-phenylprop-2-enoyl)pyrrolidin-2-yl]but-2-enamide 163029777 Click to see 298.40 unknown https://doi.org/10.1021/NP990454D
2-methyl-N-[1-(3-phenylprop-2-enoyl)pyrrolidin-2-yl]butanamide 57369849 Click to see 300.40 unknown https://doi.org/10.1021/NP990454D
Odorinol 6440456 Click to see CCC(C)(C(=O)NC1CCCN1C(=O)C=CC2=CC=CC=C2)O 316.40 unknown https://doi.org/10.1021/NP990454D
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
(2R,3S,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3S,4R)-2-(3,4-dihydroxyphenyl)-4-[(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-8-[(2R,3S,4S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol 101228664 Click to see C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=C3C(=CC(=C4C5C(C(OC6=C(C(=CC(=C56)O)O)C7C(C(OC8=CC(=CC(=C78)O)O)C9=CC(=C(C=C9)O)O)O)C1=CC(=C(C=C1)O)O)O)O)O)C1=CC(=C(C=C1)O)O)O)O)O)C1=CC(=C(C=C1)O)O)O 1155.00 unknown via CMAUP database
Procyanidin B3 146798 Click to see 578.50 unknown via CMAUP database
Procyanidin C2 11182062 Click to see 866.80 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
(2R,3S,4S)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,4,5,7-tetrol 440833 Click to see 306.27 unknown via CMAUP database
Catechin 9064 Click to see 290.27 unknown via CMAUP database
Epicatechin 72276 Click to see 290.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins / Epigallocatechins
(-)-Gallocatechin 9882981 Click to see 306.27 unknown via CMAUP database
Epigallocatechin 72277 Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 306.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Anthocyanins / Anthocyanidin-3-O-glycosides
Delphinidin 3-O-glucoside cation 443650 Click to see C1=C(C=C(C(=C1O)O)O)C2=[O+]C3=CC(=CC(=C3C=C2OC4C(C(C(C(O4)CO)O)O)O)O)O 465.40 unknown via CMAUP database
Kuromanin 441667 Click to see C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O 449.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Anthocyanins / Anthocyanidin-5-O-glycosides
3',5'-Dimethoxy-4',7-dihydroxy-5-(beta-D-glucopyranosyloxy)-3-[(6-O-acetyl-beta-D-glucopyranosyl)oxy]flavylium 101918997 Click to see CC(=O)OCC1C(C(C(C(O1)OC2=C([O+]=C3C=C(C=C(C3=C2)OC4C(C(C(C(O4)CO)O)O)O)O)C5=CC(=C(C(=C5)OC)O)OC)O)O)O 697.60 unknown via CMAUP database
Cyanin 441688 Click to see 611.50 unknown via CMAUP database
Malvin 441765 Click to see 655.60 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-((2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-yl)Oxy-Chromen-4-one 12304323 Click to see 464.40 unknown via CMAUP database
Hyperoside 5281643 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 464.40 unknown via CMAUP database
kaempferol 3-O-beta-L-glucopyranoside 9911508 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown via CMAUP database
Quercetin 3-(6''-galloylgalactoside) 5491814 Click to see 616.50 unknown via CMAUP database
Quercetin 3-(6''-galloylglucoside) 9830456 Click to see 616.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
(2R)-N-[(2S)-1-[(1R,9R,10S,11R,12S)-1,12-dihydroxy-3,5-dimethoxy-9-(4-methoxyphenyl)-10-phenyl-8-oxatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene-11-carbonyl]pyrrolidin-2-yl]-2-hydroxy-2-methylbutanamide 101027448 Click to see 646.70 unknown https://doi.org/10.1021/NP990454D
[1-Hydroxy-10-[2-[(2-hydroxy-2-methylbutanoyl)amino]pyrrolidine-1-carbonyl]-3,5-dimethoxy-9-(4-methoxyphenyl)-11-phenyl-8-oxatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-12-yl] acetate 73657039 Click to see 688.80 unknown https://doi.org/10.1021/NP990454D
[1-Hydroxy-11-[2-[(2-hydroxy-2-methylbutanoyl)amino]pyrrolidine-1-carbonyl]-3,5-dimethoxy-9-(4-methoxyphenyl)-10-phenyl-8-oxatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-12-yl] acetate 73657038 Click to see 688.80 unknown https://doi.org/10.1021/NP990454D
Aglaxiflorin B 10652212 Click to see CCC(C)(C(=O)NC1CCCN1C(=O)C2C(C3(C(C2(C4=C(O3)C=C(C=C4OC)OC)O)OC(=O)C)C5=CC=C(C=C5)OC)C6=CC=CC=C6)O 688.80 unknown https://doi.org/10.1021/NP990454D
Aglaxiflorin C 44583746 Click to see CCC(C)(C(=O)NC1CCCN1C(=O)C2C(C3(C(C2(OC4=C3C(=CC(=C4)OC)OC)C5=CC=C(C=C5)OC)OC(=O)C)O)C6=CC=CC=C6)O 688.80 unknown https://doi.org/10.1021/NP990454D
N-[1-[1,12-dihydroxy-3,5-dimethoxy-9-(4-methoxyphenyl)-10-phenyl-8-oxatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene-11-carbonyl]pyrrolidin-2-yl]-2-hydroxy-2-methylbutanamide 73657040 Click to see 646.70 unknown https://doi.org/10.1021/NP990454D
> Phenylpropanoids and polyketides / Isocoumarins and derivatives
(1R)-7,8,9-trihydroxy-3,5-dioxo-1,2-dihydrocyclopenta[c]isochromene-1-carboxylic acid 102004656 Click to see 292.20 unknown via CMAUP database
> Phenylpropanoids and polyketides / Stilbenes / Stilbene glycosides
[(2S,3S,4S,5R,6R)-2-[5-[(1S,3R,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-3a-yl]-2-methoxyphenoxy]-5-hydroxy-4-methoxy-6-methyloxan-3-yl] acetate 163001617 Click to see 652.70 unknown https://doi.org/10.1021/NP990454D
[2-[5-(1,8b-dihydroxy-6,8-dimethoxy-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-3a-yl)-2-methoxyphenoxy]-5-hydroxy-4-methoxy-6-methyloxan-3-yl] acetate 85270469 Click to see 652.70 unknown https://doi.org/10.1021/NP990454D
> Phenylpropanoids and polyketides / Tannins
(2R,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4,5-trihydroxybenzoate) 9876301 Click to see 940.70 unknown via CMAUP database
1,2,3,6-Tetra-O-Galloyl-Beta-D-Glucose 73178 Click to see 788.60 unknown via CMAUP database
beta-Glucogallin 124021 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OC2C(C(C(C(O2)CO)O)O)O 332.26 unknown via CMAUP database
Penta-O-galloyl-beta-D-glucose 65238 Click to see 940.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
1,2-Di-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl-beta-D-glucopyranose 101259865 Click to see 786.60 unknown via CMAUP database
3-O-digalloyl-1,2,4,6-tetra-O-beta-D-galloylglucose 16164119 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)OC(=O)C6=CC(=C(C(=C6)O)O)O)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O 1092.80 unknown via CMAUP database
Ellagic Acid 5281855 Click to see 302.19 unknown via CMAUP database
Geraniin 3001497 Click to see 952.60 unknown via CMAUP database
Xcxwmhrrisfuff-xngpzlstsa- 21636130 Click to see 1110.80 unknown via CMAUP database

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