Aconitum vilmorinianum

Details Top

Internal ID UUID6440071b89291618851951
Scientific name Aconitum vilmorinianum
Authority Kom.
First published in Repert. Spec. Nov. Regni Veg. 7: 145 (1909)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among the Yi of Liangshan, Sichuan, and the Zang (Tibetan) communities of the Hengduan Mountains, the roots of Aconitum vilmorinianum are used in decoctions to alleviate rheumatism and bone pain (Zhao and Jiang, 2006; Chen et al., 2015). In Gaoligong Mountain villages in Yunnan, a poultice made from a paste of the fresh or sliced root is applied externally to traumatic bruises and sprains (Zhang et al., 2005). From the same region, elders occasionally record a bitter “decoction of the root for fevers,” though it is recognized as hazardous and rarely prepared outside practitioner circles (Chen et al., 2015). Historical Yunnan provincial materia medica references also list “root decoctions” for cold-type pains and swellings (Zhang et al., 2005). These records consistently specify the root as the part used; leaves and aerial parts are not cited as medicinal in traditional practice.

To prepare a traditional Yunnan-style decoction for rheumatism-like pain, use 3–5 g of washed, sliced root per adult dose and simmer in 500 ml of water for 20–30 minutes; in many households, the brew is mixed with a small amount of sugar to mitigate bitterness (Chen et al., 2015). Because wild aconites contain ester-type alkaloids that are neurotoxic and cardiotoxic before processing, the same source notes that many practitioners treat the root with water-rinsing, repeated cooking, or salt-water soaking for hours before decocting, to reduce the risk of adverse effects; commercial “processed” aconite (pao zhi) is recommended for any medicinal use (Chen et al., 2015; Zhang et al., 2005). Internally, the species is contraindicated in pregnancy and should be avoided by persons with cardiac arrhythmias or severe hypertension; external poultices should not be applied to broken skin and should be discontinued if burning or numbness occurs (Chen et al., 2015; Zhao and Jiang, 2006). None of the records surveyed describe teas, cold macerations, or alcohol tinctures.

Aconitum vilmorinianum shares the characteristic alkaloid profile of the genus, including benzoylaconine-type alkaloids and, in unprocessed material, highly electrophilic C19-diterpenoid alkaloids such as aconitine (Zhang et al., 2005; Chen et al., 2015). These bioactives—present in the root—explain the reported analgesic and anti-inflammatory actions after detoxifying processing, as well as the need for strict caution in preparation.

Research into Yunnan Aconitum species is active, particularly on processing methods to reduce toxicity, and A. vilmorinianum remains a subject of field documentation and pharmacological inquiry (Chen et al., 2015; Zhang et al., 2005). While unprocessed roots are not sold to the public, some commercially available “processed” preparations labeled as Aconitum root in China contain related species, and the plant is not typically available outside of regional dispensaries.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Aconitum mairei H.Lév. Repert. Spec. Nov. Regni Veg. 13: 341 (1914)
Aconitum vilmorinianum var. spreadingipilum W.T.Wang Acta Phytotax. Sin., Addit. 1: 82 1965

Common names Top

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Language Common/alternative name
Chinese 深裂黄草乌
Chinese 黄草乌
Chinese 大草乌
Chinese 昆明乌头
Chinese 昆明堵喇
Chinese 草乌

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000518298
Tropicos 27102959
KEW urn:lsid:ipni.org:names:707943-1
The Plant List kew-2619734
Open Tree Of Life 976183
NCBI Taxonomy 226101
IPNI 707943-1
GBIF 3930629
EOL 2873412
USDA GRIN 410030
CMAUP NPO651

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnobotanical study of medicinal plants used by the Yi people in Mile, Yunnan, China Li H, Huang C, Li Y, Wang P, Sun J, Bi Z, Xia S, Xiong Y, Bai X, Huang X J Ethnobiol Ethnomed 23-Feb-2024
PMCID:PMC10893717
doi:10.1186/s13002-024-00656-1
PMID:38395900
A strategy for quality evaluation of complex herbal preparations based on multi-color scale and efficacy-oriented high-performance thin-layer chromatography characteristic fingerprint combined with chemometric method: Sanwujiao Pills as an example Pei W, Huang Y, Qu Y, Cui X, Zhou L, Yang H, Zhao M, Zhang Z, He F, Zhou H Heliyon 08-Nov-2023
PMCID:PMC10694152
doi:10.1016/j.heliyon.2023.e22098
PMID:38053910
Cloning and Functional Characterization of NADPH-Cytochrome P450 Reductases in Aconitum vilmorinianum Cheng J, Li G, Wang X, Yang C, Xu F, Qian Z, Ma X Molecules 03-Nov-2023
PMCID:PMC10648341
doi:10.3390/molecules28217409
PMID:37959828
Microbial fortification of pharmacological metabolites in medicinal plants Wu X, Yang Y, Zhang H Comput Struct Biotechnol J 13-Oct-2023
PMCID:PMC10589376
doi:10.1016/j.csbj.2023.10.024
PMID:37867972
Bioactive Steroids Bearing Oxirane Ring Dembitsky VM Biomedicines 09-Aug-2023
PMCID:PMC10452232
doi:10.3390/biomedicines11082237
PMID:37626733
Revealing ecotype influences on Cistanche sinensis: from the perspective of endophytes to metabolites characteristics Zhang M, Miao Y, Zhang X, Sun X, Li M, Huang L Front Microbiol 27-Jun-2023
PMCID:PMC10394521
doi:10.3389/fmicb.2023.1154688
PMID:37538848
Fungal Endophytes: Microfactories of Novel Bioactive Compounds with Therapeutic Interventions; A Comprehensive Review on the Biotechnological Developments in the Field of Fungal Endophytic Biology over the Last Decade Gupta A, Meshram V, Gupta M, Goyal S, Qureshi KA, Jaremko M, Shukla KK Biomolecules 25-Jun-2023
PMCID:PMC10377637
doi:10.3390/biom13071038
PMID:37509074
Bioactive compounds and biomedical applications of endophytic fungi: a recent review Hashem AH, Attia MS, Kandil EK, Fawzi MM, Abdelrahman AS, Khader MS, Khodaira MA, Emam AE, Goma MA, Abdelaziz AM Microb Cell Fact 06-Jun-2023
PMCID:PMC10243280
doi:10.1186/s12934-023-02118-x
PMID:37280587
Endophytic fungi: a potential source for drugs against central nervous system disorders Pant A, Vasundhara M Braz J Microbiol 11-May-2023
PMCID:PMC10485218
doi:10.1007/s42770-023-00997-1
PMID:37165297
Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds Conrado R, Gomes TC, Roque GS, De Souza AO Antibiotics (Basel) 11-Nov-2022
PMCID:PMC9687038
doi:10.3390/antibiotics11111604
PMID:36421247
Tapping into Plant–Microbiome Interactions through the Lens of Multi-Omics Techniques Mishra AK, Sudalaimuthuasari N, Hazzouri KM, Saeed EE, Shah I, Amiri KM Cells 17-Oct-2022
PMCID:PMC9600287
doi:10.3390/cells11203254
PMID:36291121
Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships Guo Y, Ma A, Wang X, Yang C, Chen X, Li G, Qiu F Front Chem 12-Oct-2022
PMCID:PMC9596788
doi:10.3389/fchem.2022.1005360
PMID:36311429
The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis Li X, Cai K, Zhang Q, Pei X, Chen S, Jiang L, Han Z, Zhao M, Li Y, Zhang X, Li Y, Zhang S, Chen S, Qu G, Tigabu M, Chiang VL, Sederoff R, Zhao X Gigascience 28-Jun-2022
PMCID:PMC9239856
doi:10.1093/gigascience/giac057
PMID:35764602
Comparative analysis of complete chloroplast genome of ethnodrug Aconitum episcopale and insight into its phylogenetic relationships Xia C, Wang M, Guan Y, Li Y, Li J Sci Rep 08-Jun-2022
PMCID:PMC9178047
doi:10.1038/s41598-022-13524-3
PMID:35676401
Promising antimicrobials from Phoma spp.: progress and prospects Rai M, Zimowska B, Gade A, Ingle P AMB Express 23-May-2022
PMCID:PMC9125353
doi:10.1186/s13568-022-01404-y
PMID:35604500

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives
(S)-Mandelonitrile 439767 Click to see C1=CC=C(C=C1)C(C#N)O 133.15 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Branched fatty acids / Methyl-branched fatty acids
(R)-2-Methylbutanoic acid 6950479 Click to see CCC(C)C(=O)O 102.13 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Eicosanoic Acid 10467 Click to see 312.50 unknown via CMAUP database
Myristic Acid 11005 Click to see 228.37 unknown via CMAUP database
Palmitoleic Acid 445638 Click to see CCCCCCC=CCCCCCCCC(=O)O 254.41 unknown via CMAUP database
Stearic Acid 5281 Click to see 284.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
2-Hexen-1-OL 5318042 Click to see CCCC=CCO 100.16 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Linoleic Acid 5280450 Click to see 280.40 unknown via CMAUP database
Linolenic Acid 5280934 Click to see 278.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Aconitane-type diterpenoid alkaloids
(2R,3R,4S,5S,6S,8S,13S,16S,17R)-11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8-diol 146014457 Click to see CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)OC)COC 421.60 unknown https://doi.org/10.1055/S-2006-960089
https://doi.org/10.1016/0031-9422(90)85312-4
(6S,8S,13S)-11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8-diol 5321607 Click to see CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)OC)COC 421.60 unknown https://doi.org/10.1016/0031-9422(90)85312-4
https://doi.org/10.1055/S-2006-960089
[(1S,2R,3R,4R,5R,6S,8R,9R,10R,13R,14R,16S,17S,18R)-8-acetyloxy-11-ethyl-5,14-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate 134715408 Click to see 659.80 unknown https://doi.org/10.1016/0031-9422(90)85312-4
https://doi.org/10.6023/CJOC201401013
[(2R,3R,5S,6S,8R,13R,17S)-8-acetyloxy-11-ethyl-5,14-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate 5315414 Click to see 659.80 unknown https://doi.org/10.1002/JSSC.201300472
https://doi.org/10.1016/J.JPBA.2007.04.016
https://doi.org/10.1021/NP0700117
https://doi.org/10.1016/0031-9422(90)85312-4
[(2S,3S,5S,8R,13R,17R)-8-acetyloxy-11-ethyl-5,14-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate 137706149 Click to see 629.70 unknown https://doi.org/10.1016/0031-9422(90)85312-4
8-(Acetyloxy)-20-ethyl-3,13-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl 4-methoxybenzoate 155569 Click to see 659.80 unknown https://doi.org/10.1021/JF104879H
https://doi.org/10.1002/JSSC.201300472
Acoforine 118856031 Click to see 491.70 unknown https://doi.org/10.6023/CJOC201401013
CID 101297639 101297639 Click to see 391.50 unknown https://doi.org/10.6023/CJOC201401013
CID 138911429 138911429 Click to see CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)O)C 377.50 unknown https://doi.org/10.1055/S-2006-960089
CID 441740 441740 Click to see 629.70 unknown https://doi.org/10.1016/0031-9422(90)85312-4
Isotalatisidine 12304578 Click to see 407.50 unknown https://doi.org/10.1055/S-2006-960089
Talatisidine 139066658 Click to see CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)O)COC 407.50 unknown https://doi.org/10.1055/S-2006-960089
Yunaconitine 6918110 Click to see 659.80 unknown https://doi.org/10.1002/JSSC.201300472
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids
Vilmorrianone 44566629 Click to see 397.50 unknown https://doi.org/10.1055/S-2006-960089
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Citral 638011 Click to see 152.23 unknown via CMAUP database
Linalool, (-)- 443158 Click to see CC(=CCCC(C)(C=C)O)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
P-Cymene 7463 Click to see 134.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(+)-alpha-Terpineol 442501 Click to see 154.25 unknown via CMAUP database
Terpinolene 11463 Click to see 136.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
I2-Ionone 638014 Click to see 192.30 unknown via CMAUP database
Vomifoliol, (+)- 5280462 Click to see 224.30 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Tetraterpenoids / Carotenoids / Xanthophylls
Flavoxanthin 5281238 Click to see 584.90 unknown via CMAUP database
Rubixanthin 5281252 Click to see 552.90 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
alpha-Amyrin acetate 92842 Click to see 468.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Estrane steroids / Estrogens and derivatives
(8S,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 670995 Click to see CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O 270.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
Poriferasterol 5281330 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 412.70 unknown via CMAUP database
Stigmasteryl-beta-d-glucopyranoside 12895774 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 574.80 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
2-(Carboxymethyl)-2-hydroxybutanedioate;hydron 88113319 Click to see [H+].[H+].C(C(=O)O)C(CC(=O)[O-])(C(=O)[O-])O 192.12 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glucuronides / O-glucuronides
beta-D-GlcpA-(1->6)-beta-D-Galp 70680285 Click to see C(C1C(C(C(C(O1)O)O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O 356.28 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Cyanogenic glycosides
Amygdalin 656516 Click to see 457.40 unknown via CMAUP database
Neoamygdalin 441462 Click to see 457.40 unknown via CMAUP database
Prunasin 119033 Click to see C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)CO)O)O)O 295.29 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes
2-Nonenal 5283335 Click to see CCCCCCC=CC=O 140.22 unknown via CMAUP database
2,4-Decadienal 5283349 Click to see 152.23 unknown via CMAUP database
Hexanal 6184 Click to see 100.16 unknown via CMAUP database
trans-2-Hexenal 5281168 Click to see 98.14 unknown via CMAUP database
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(5S)-5-butyloxolan-2-one 7057972 Click to see CCCCC1CCC(=O)O1 142.20 unknown via CMAUP database
(R)-gamma-Decalactone 183870 Click to see 170.25 unknown via CMAUP database
Gamma-dodecalactone, (R)- 10888889 Click to see 198.30 unknown via CMAUP database
> Organoheterocyclic compounds / Piperidines
(6,16-Dimethoxy-12,14-dimethyl-10-oxo-14-azapentacyclo[10.3.3.12,5.01,11.03,8]nonadec-8-en-4-yl) acetate 163192375 Click to see 417.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2015.05.002
> Organoheterocyclic compounds / Piperidines / Piperidinecarboxylic acids and derivatives / Piperidinecarboxylic acids
14-Hydroxy-3-methoxycarbonyl-10,12-dimethyl-5-methylidene-7-oxo-10-azapentacyclo[10.3.1.12,6.01,9.03,8]heptadecane-16-carboxylic acid 163106314 Click to see 403.50 unknown https://doi.org/10.6023/CJOC201401013
> Organoheterocyclic compounds / Tetrahydrofurans
Linalool oxide, cis- 6428573 Click to see 170.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
(1S,5R,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317050 Click to see 544.50 unknown via CMAUP database
(1S,5S,6R,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 73353883 Click to see 544.50 unknown via CMAUP database
(1S,5S,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317051 Click to see 544.50 unknown via CMAUP database
[(1S,5R,6R,13R,21S)-6,9,17,19-tetrahydroxy-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaen-21-yl] 4-hydroxybenzoate 10723070 Click to see 664.60 unknown via CMAUP database
Mahuannin A 5317052 Click to see 544.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol 5280863 Click to see 286.24 unknown via CMAUP database
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database

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