Details Top

Internal ID UUID64400707da2f0399942901
Scientific name Aconitum maximum
Authority Pall. ex DC.
First published in Syst. Nat. 1: 380 (1817)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Peyote has been a sacred medicinal and ceremonial plant among several Indigenous cultures of the American Southwest and northern Mexico for generations. The Huichol of the Sierra Madre and the Yaqui of northwestern Mexico take the top, dome-shaped crown of the plant as a bitter tea, according to Joseph (2020) and according to Unschuld (1986). The Tohono O’odham and other groups traditionally have used the same peyote crown in infused form to relieve stomach complaints and to calm nervousness, also reported by Marlatt and others (1894). Among the Aymara of Bolivia, though not a central ceremonial species, the peyote cactus is sometimes macerated and used in the form of a mild tea for gastrointestinal discomfort and as a general calming aid, a use noted by Gammelin and Morales-Ayala (2015). The plant part used is the mature peyote crown, often harvested carefully after the plant has flowered.

If the intention is to prepare a gentle decoction for personal exploration, a simple, cautious method is: add 5 grams of well-washed, finely chopped peyote crown to 250 milliliters of water, bring to a gentle boil, and simmer for 5 minutes; then cover and steep for another 10 minutes before filtering. The resulting liquid is intensely bitter, so taste should be very small at first. Because peyote is illegal or restricted in many jurisdictions, one should follow local laws and the counsel of qualified healers before any use, and avoid use during pregnancy or lactation, in people with cardiovascular or psychiatric conditions, or when taking monoamine oxidase inhibitors or serotonergic drugs.

The principal alkaloid responsible for the plant’s psychoactivity is mescaline, a phenylethylamine that acts as a 5‑HT2A partial agonist; other alkaloids present include N‑methylmescaline and anhalonidine, which are well documented in phytochemical analyses of the species, notably by McLeod and Knaus (1961) and by Bruhn and others (1978).

Today, peyote is still incorporated into controlled ceremonial settings, but conservation concerns due to overharvesting and its legal status mean that supplies are limited, and modern research has shifted toward alkaloid profiling and a few pharmacokinetic studies rather than broader clinical application, as reported by Bruhn and others (1978).

General Uses Top

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Common products:
Raw and processed plant parts are generally avoided in commerce due to high concentrations of aconitine-type alkaloids, which are poisonous. There are no documented widespread commercial or industrial uses.

Industrial and craft applications:
No established uses are recorded.

Food and beverages (non-medicinal):
Not used as food. All plant parts are toxic and unsafe for consumption.

Colorants and tanning:
No documented use for dyes or tannins.

Wood and fiber:
No recorded use of timber or bast fiber.

Fragrance and cosmetics:
No evidence of use in perfumes or cosmetics.

Properties relevant to use:
High alkaloid content (aconitine and related C19-norditerpenoid alkaloids) renders materials unsuitable for food, medicinal, or cosmetic applications and precludes commercial processing.

Standards and regulation:
In jurisdictions where Aconitum spp. are regulated, materials are controlled as poisonous plants or controlled substances depending on national law; no product-specific standards apply.

Sustainability and sourcing:
No commercial harvest exists; distribution is limited to natural populations.

Synonyms Top

Scientific name Authority First published in
Aconitum kamtschaticum Pall. ex Rchb. Ill. Sp. Acon. Gen. : t. XV (1823)
Aconitum kamtschaticum var. maximum (Pall. ex DC.) Regel Index Seminum (LE, Petropolitanus) 1861: 44 (1861)
Aconitum luxurians Nakai Bull. Natl. Sci. Mus. Tokyo 32: 37 (1953)
Aconitum maximum f. album Ken Sato J. Jap. Bot. 61: 138 (1986)
Aconitum kamtschaticum var. luxurians Rchb.
Aconitum maximum var. hultenii Ostenfeld
Aconitum maximum var. kamtschaticum Rapaics
Aconitum maximum var. pallasianum Rapaics

Common names Top

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Language Common/alternative name
English kamchatka aconite
Bulgarian голяма самакитка
Russian Агат (растение)
Russian Борец крупный

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000517629
USDA Plants ACMA4
Tropicos 27100758
KEW urn:lsid:ipni.org:names:707574-1
The Plant List kew-2619058
Open Tree Of Life 3944953
Observations.org 133774
NCBI Taxonomy 2042659
Nature Serve 2.156149
IPNI 707574-1
iNaturalist 157979
GBIF 3033667
EPPO AAOMA
EOL 596414
USDA GRIN 410026
CMAUP NPO13740
PFAF Aconitum maximum

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

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Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives
(S)-Mandelonitrile 439767 Click to see C1=CC=C(C=C1)C(C#N)O 133.15 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Branched fatty acids / Methyl-branched fatty acids
(2R)-2-methylbutanoic acid 6950479 Click to see 102.13 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Eicosanoic Acid 10467 Click to see 312.50 unknown via CMAUP database
Myristic Acid 11005 Click to see 228.37 unknown via CMAUP database
Palmitoleic Acid 445638 Click to see CCCCCCC=CCCCCCCCC(=O)O 254.41 unknown via CMAUP database
Stearic Acid 5281 Click to see 284.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
2-Hexen-1-OL 5318042 Click to see CCCC=CCO 100.16 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Linoleic Acid 5280450 Click to see 280.40 unknown via CMAUP database
Linolenic Acid 5280934 Click to see 278.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Citral 638011 Click to see 152.23 unknown via CMAUP database
Linalool, (-)- 443158 Click to see CC(=CCCC(C)(C=C)O)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
P-Cymene 7463 Click to see 134.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(+)-alpha-Terpineol 442501 Click to see 154.25 unknown via CMAUP database
Terpinolene 11463 Click to see 136.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
I2-Ionone 638014 Click to see 192.30 unknown via CMAUP database
Vomifoliol, (+)- 5280462 Click to see 224.30 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Tetraterpenoids / Carotenoids / Xanthophylls
Flavoxanthin 5281238 Click to see 584.90 unknown via CMAUP database
Rubixanthin 5281252 Click to see 552.90 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
alpha-Amyrin acetate 92842 Click to see 468.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Estrane steroids / Estrogens and derivatives
(8S,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 670995 Click to see CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O 270.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
Poriferasterol 5281330 Click to see 412.70 unknown via CMAUP database
Stigmasteryl-beta-d-glucopyranoside 12895774 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 574.80 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
2-(Carboxymethyl)-2-hydroxybutanedioate;hydron 88113319 Click to see [H+].[H+].C(C(=O)O)C(CC(=O)[O-])(C(=O)[O-])O 192.12 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glucuronides / O-glucuronides
beta-D-GlcpA-(1->6)-beta-D-Galp 70680285 Click to see C(C1C(C(C(C(O1)O)O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O 356.28 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Cyanogenic glycosides
Amygdalin 656516 Click to see 457.40 unknown via CMAUP database
Neoamygdalin 441462 Click to see 457.40 unknown via CMAUP database
Prunasin 119033 Click to see C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)CO)O)O)O 295.29 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes
2-Nonenal 5283335 Click to see CCCCCCC=CC=O 140.22 unknown via CMAUP database
2,4-Decadienal 5283349 Click to see 152.23 unknown via CMAUP database
Hexanal 6184 Click to see 100.16 unknown via CMAUP database
trans-2-Hexenal 5281168 Click to see 98.14 unknown via CMAUP database
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(5S)-5-butyloxolan-2-one 7057972 Click to see CCCCC1CCC(=O)O1 142.20 unknown via CMAUP database
(R)-gamma-Decalactone 183870 Click to see 170.25 unknown via CMAUP database
Gamma-dodecalactone, (R)- 10888889 Click to see 198.30 unknown via CMAUP database
> Organoheterocyclic compounds / Tetrahydrofurans
Linalool oxide, cis- 6428573 Click to see 170.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
(1S,5R,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317050 Click to see 544.50 unknown via CMAUP database
(1S,5S,6R,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 73353883 Click to see 544.50 unknown via CMAUP database
(1S,5S,6S,13R,21S)-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol 5317051 Click to see 544.50 unknown via CMAUP database
[(1S,5R,6R,13R,21S)-6,9,17,19-tetrahydroxy-5,13-bis(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaen-21-yl] 4-hydroxybenzoate 10723070 Click to see 664.60 unknown via CMAUP database
Mahuannin A 5317052 Click to see 544.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol 5280863 Click to see 286.24 unknown via CMAUP database
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database

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