Properties relevant to use:
Stephania delavayi (Menispermaceae) has been investigated primarily for its secondary metabolites rather than for commercial products. Phytochemical surveys of the roots and aerial parts consistently report a rich suite of bisbenzylisoquinoline alkaloids, including stephanine, daurinol, stepharanine, fangchinoline, and related compounds. These alkaloids are readily extracted with polar organic solvents (methanol, ethanol) under reflux or Soxhlet conditions, yielding extracts that display characteristic UV absorptions (λmax ≈ 260–290 nm) and mass spectra dominated by protonated molecular ions at m/z 300–650 Da. The presence of a free phenolic hydroxyl in several members imparts moderate water solubility after basification, facilitating subsequent acid‑base partitioning.

The structural diversity and typical NMR signatures of these bisbenzylisoquinolines make S. delavayi a useful reference source for natural‑product chemists. Isolated compounds are employed as analytical standards for dereplication in metabolomic studies, for the calibration of HPLC‑UV and LC‑MS methods targeting isoquinoline alkaloids, and as authentic samples in the development of new synthetic routes to bisbenzylisoquinoline scaffolds. In addition, the plant’s alkaloid profile has been incorporated into chemotaxonomic investigations that aim to differentiate Stephania species, underscoring its role as a model for comparative phytochemistry.

No documented commercial or industrial applications—such as timber, fiber, dyes, gums, food products, cosmetics, biofuels, or materials—have been reported for S. delavayi. Consequently, the species is not subject to timber‑grading standards, food‑additive regulations, or sustainability certifications. Its utilization remains confined to research contexts where the alkaloid constituents serve as chemical probes and reference materials.

Synonyms Top

Scientific name	Authority	First published in
Stephania graciliflora	Yamam.	J. Soc. Trop. Agric. 12: 243 (1940)

Common names Top

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Filter by language:

Language	Common/alternative name
Chinese	一文钱
Chinese	地不容
Chinese	山乌龟(地不容)
Chinese	纤花千金藤
Chinese	小寒药
Chinese	一文錢

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Asia-temperate click to expand
- China
  - China South-central

Asia-tropical click to expand
- Indo-China
  - Myanmar

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0001238629
Tropicos	50098883
KEW	urn:lsid:ipni.org:names:581412-1
The Plant List	tro-50098883
Open Tree Of Life	32397
NCBI Taxonomy	216145
IPNI	581412-1
GBIF	5592626
EOL	5125328
CMAUP	NPO9266

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

Ethnobotanical study of medicinal plants used by the Yi people in Mile, Yunnan, China

Li H, Huang C, Li Y, Wang P, Sun J, Bi Z, Xia S, Xiong Y, Bai X, Huang X

J Ethnobiol Ethnomed

23-Feb-2024

PMCID:	PMC10893717
doi:	10.1186/s13002-024-00656-1
PMID:	38395900

The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19

Xia B, Zheng L, Li Y, Sun W, Liu Y, Li L, Pang J, Chen J, Li J, Cheng H

Front Pharmacol

31-Jul-2023

PMCID:	PMC10423819
doi:	10.3389/fphar.2023.1098972
PMID:	37583901

Strengthening Structures in the Petiole–Lamina Junction of Peltate Leaves

Wunnenberg J, Rjosk A, Neinhuis C, Lautenschläger T

Biomimetics (Basel)

02-Apr-2021

PMCID:	PMC8167582
doi:	10.3390/biomimetics6020025
PMID:	33918405

Ethnobotany and diversity of medicinal plants used by the Buyi in eastern Yunnan, China

Xiong Y, Sui X, Ahmed S, Wang Z, Long C

Plant Divers

07-Oct-2020

PMCID:	PMC7936110
doi:	10.1016/j.pld.2020.09.004
PMID:	33733008

Potential Hepatotoxins Found in Herbal Medicinal Products: A Systematic Review

Quan NV, Dang Xuan T, Teschke R

Int J Mol Sci

16-Jul-2020

PMCID:	PMC7404040
doi:	10.3390/ijms21145011
PMID:	32708570

Ethnomedicine study on traditional medicinal plants in the Wuliang Mountains of Jingdong, Yunnan, China

Gao L, Wei N, Yang G, Zhang Z, Liu G, Cai C

J Ethnobiol Ethnomed

19-Aug-2019

PMCID:	PMC6699132
doi:	10.1186/s13002-019-0316-1
PMID:	31426826

The Invasive Liriomyza huidobrensis (Diptera: Agromyzidae): Understanding Its Pest Status and Management Globally

Weintraub PG, Scheffer SJ, Visser D, Valladares G, Soares Correa A, Shepard BM, Rauf A, Murphy ST, Mujica N, MacVean C, Kroschel J, Kishinevsky M, Joshi RC, Johansen NS, Hallett RH, Civelek HS, Chen B, Metzler HB

J Insect Sci

28-Feb-2017

PMCID:	PMC5388319
doi:	10.1093/jisesa/iew121
PMID:	28423426

Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements

Yue Q, Gao G, Zou G, Yu H, Zheng X

Biomed Res Int

23-Jan-2017

PMCID:	PMC5292383
doi:	10.1155/2017/8412508
PMID:	28232946

FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression

DE XU H, CHO SC, BANG MA, BAE CS, CHOI Y, LI YC, LIM SK, SHIM J, PARK DH

Int J Oncol

27-Mar-2015

PMCID:	PMC4441289
doi:	10.3892/ijo.2015.2940
PMID:	25823424

Pharmacokinetic profile of phytoconstituent(s) isolated from medicinal plants—A comprehensive review

Mehta P, Shah R, Lohidasan S, Mahadik KR

J Tradit Complement Med

28-Jan-2015

PMCID:	PMC4624361
doi:	10.1016/j.jtcme.2014.11.041
PMID:	26587392

6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation

LI YC, KIM BH, CHO SC, BANG MA, KIM S, PARK DH

Int J Oncol

07-Nov-2014

PMCID:	PMC4277248
doi:	10.3892/ijo.2014.2739
PMID:	25384584

Immunostimulating Effects of Extract of Acanthopanax sessiliflorus

Kim JH, Shin EH, Lee HY, Lee BG, Park SH, Moon DI, Goo GC, Kwon DY, Yang HJ, Kim OJ, Oh HG

Exp Anim

01-Aug-2013

PMCID:	PMC4160943
doi:	10.1538/expanim.62.247
PMID:	23903060

Differential Effect of Isoflurane, Medetomidine, and Urethane on BOLD Responses to Acute Levo-Tetrahydropalmatine in the Rat

Liu X, Li R, Yang Z, Hudetz AG, Li SJ

Magn Reson Med

28-Dec-2011

PMCID:	PMC3376170
doi:	10.1002/mrm.23243
PMID:	22213080

Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine, stress or drug-associated cues in rats

Figueroa-Guzman Y, Mueller C, Vranjkovic O, Wisniewski S, Yang Z, Li SJ, Bohr C, Graf EN, Baker DA, Mantsch JR

Drug Alcohol Depend

31-Dec-2010

PMCID:	PMC3466100
doi:	10.1016/j.drugalcdep.2010.11.023
PMID:	21196089

Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats

Mantsch JR, Wisniewski S, Vranjkovic O, Peters C, Becker A, Valentine A, Li SJ, Baker DA, Yang Z

Pharmacol Biochem Behav

09-Sep-2010

PMCID:	PMC2956862
doi:	10.1016/j.pbb.2010.08.016
PMID:	20816889

Phytochemical Profile Top

Add a new one!

Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / 6,6a-secoaporphines
Phenanthro(3,4-d)-1,3-dioxole-5-ethanamine, N,N-dimethyl-	161379	Click to see CN(C)CCC1=CC2=C(C3=C1C=CC4=CC=CC=C43)OCO2	293.40	unknown	via CMAUP database
> Alkaloids and derivatives / Aporphines
(-)-Phanostenine	12305138	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC(=C(C=C54)O)OC)OCO3	325.40	unknown	via CMAUP database
(-)-Stephanine; (R)-(-)-Stephanine; 8-Methoxy-1,2-(methylenedioxy)-6abeta-aporphine; Stephanin; l-Stephanine	10335495	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC=C5OC)OCO3	309.40	unknown	via CMAUP database
(+/-)-Dicentrine	630859	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC(=C(C=C54)OC)OC)OCO3	339.40	unknown	via CMAUP database
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-, (7R)-	333544	Click to see	339.40	unknown	via CMAUP database
Cassythicine	442194	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC(=C(C=C54)OC)O)OCO3	325.40	unknown	via CMAUP database
Dehydrocrebanine	149600	Click to see CN1CCC2=CC3=C(C4=C5C=CC(=C(C5=CC1=C24)OC)OC)OCO3	337.40	unknown	via CMAUP database
Dehydrodicentrine	3084326	Click to see CN1CCC2=CC3=C(C4=C5C=C(C(=CC5=CC1=C24)OC)OC)OCO3	337.40	unknown	via CMAUP database
Isolaureline	12311076	Click to see	309.40	unknown	via CMAUP database
Stephanine	160501	Click to see CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC=C5OC)OCO3	309.40	unknown	via CMAUP database
Stesakine	157110	Click to see	325.40	unknown	via CMAUP database
> Alkaloids and derivatives / Aporphines / Hydroxy-7-aporphines
Oliveridine	13891891	Click to see	325.40	unknown	via CMAUP database
> Alkaloids and derivatives / Hasubanan alkaloids
(1S,13R)-14,15-dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[11.4.3.01,13.02,10.04,8]icosa-2,4(8),9,14-tetraene-16,19-dione	162844853	Click to see	371.40	unknown	https://doi.org/10.1007/BF00564472
(1S,13S)-14,15-dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[11.4.3.01,13.02,10.04,8]icosa-2,4(8),9,14-tetraen-16-one	44584410	Click to see	357.40	unknown	https://doi.org/10.1007/BF00567931
14,15-Dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[11.4.3.01,13.02,10.04,8]icosa-2,4(8),9,14-tetraene-16,19-dione	21769995	Click to see	371.40	unknown	https://doi.org/10.1007/BF00564472
Delavaine	360850	Click to see CN1CCC23C1(CCC4=CC5=C(C=C42)OCO5)C(=C(C(=O)C3)OC)OC	357.40	unknown	https://doi.org/10.1007/BF00567931
> Alkaloids and derivatives / Morphinans
(1R,9S,10R)-4,5,12,13-tetramethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6,12-tetraen-11-one	162996564	Click to see	373.40	unknown	https://doi.org/10.1007/BF00570667
14,15-Dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[10.5.3.01,13.02,10.04,8]icosa-2,4(8),9,14-tetraene-16,19-dione	5320322	Click to see	371.40	unknown	via CMAUP database
4,5,12,13-Tetramethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6,12-tetraen-11-one	13855901	Click to see	373.40	unknown	https://doi.org/10.1007/BF00570667
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
Stepholidine	6917970	Click to see	327.40	unknown	via CMAUP database
Tetrahydropalmatine	72301	Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC	355.40	unknown	via CMAUP database
> Benzenoids / Phenanthrenes and derivatives
O-Methylpallidine	10405046	Click to see	341.40	unknown	via CMAUP database
Salutaridine	5408233	Click to see CN1CCC23C=C(C(=O)C=C2C1CC4=C3C(=C(C=C4)OC)O)OC	327.40	unknown	via CMAUP database
> Lignans, neolignans and related compounds
1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-,(14aS,26aR)-	360849	Click to see	606.70	unknown	via CMAUP database
Cepharanthine	10206	Click to see	606.70	unknown	via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters / Fatty acid methyl esters
Methyl Decanoate	8050	Click to see	186.29	unknown	via CMAUP database
Methyl Laurate	8139	Click to see CCCCCCCCCCCC(=O)OC	214.34	unknown	via CMAUP database
Methyl Oleate	5364509	Click to see	296.50	unknown	via CMAUP database
Methyl Palmitate	8181	Click to see	270.50	unknown	via CMAUP database
Methyl palmitoleate	643801	Click to see	268.40	unknown	via CMAUP database
Methyl Pentadecanoate	23518	Click to see	256.42	unknown	via CMAUP database
Methyl Stearate	8201	Click to see CCCCCCCCCCCCCCCCCC(=O)OC	298.50	unknown	via CMAUP database
Methyl Tetradecanoate	31284	Click to see CCCCCCCCCCCCCC(=O)OC	242.40	unknown	via CMAUP database
Methyl tridecanoate	15608	Click to see	228.37	unknown	via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Methyl linoleate	5284421	Click to see	294.50	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(8aR,9S)-5,7,7-trimethyl-6,8,8a,9-tetrahydro-4H-azuleno[5,6-c]furan-9-ol	10466485	Click to see	232.32	unknown	via CMAUP database
Furandiol	181229	Click to see	250.33	unknown	via CMAUP database
Furanether A	155911	Click to see	232.32	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
(5R,5aR,8aR,9S,9aS)-9-hydroxy-5,7,7-trimethyl-1,5,5a,6,8,8a,9,9a-octahydroazuleno[5,6-c]furan-3-one	14109864	Click to see CC1C=C2C(COC2=O)C(C3C1CC(C3)(C)C)O	250.33	unknown	via CMAUP database
(5R,5aR,8aR,9S,9aS)-9,9a-dihydroxy-5,7,7-trimethyl-5,5a,6,8,8a,9-hexahydro-1H-azuleno[5,6-c]furan-3-one	21724722	Click to see CC1C=C2C(=O)OCC2(C(C3C1CC(C3)(C)C)O)O	266.33	unknown	via CMAUP database
Blennin C	14412879	Click to see CC(CC1=C(COC1=O)CO)C2=CCC(C2)(C)C	250.33	unknown	via CMAUP database
Lactarorufin A	10869217	Click to see CC1(CC2C(C1)C(CC3=C(C2O)COC3=O)(C)O)C	266.33	unknown	via CMAUP database
Rufuslactone	15330797	Click to see CC1(CC2C(C1)C3(CC4=C(C2O3)COC4=O)C)C	248.32	unknown	via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cholestane steroids / Cholesterols and derivatives
(3S,9R,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol	7568440	Click to see	384.60	unknown	via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroid lactones / Cardenolides and derivatives / Cardenolide glycosides and derivatives
Cerberin	10031063	Click to see	576.70	unknown	via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Cerveratrum-type alkaloids
(1R,2S,6S,9S,11R,14S,15S,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-diol	101634962	Click to see	415.70	unknown	via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acid derivatives / Carboxylic acid esters / Methyl esters
methyl (S)-lactate	94386	Click to see	104.10	unknown	via CMAUP database
> Organic oxygen compounds / Organic oxides
Velleral	14412869	Click to see CC1C=C(C(=CC2C1CC(C2)(C)C)C=O)C=O	232.32	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Primary alcohols
Vellerol	180721	Click to see CC1C=C(C(=CC2C1CC(C2)(C)C)CO)C=O	234.33	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Secondary alcohols
(3aR,4S,5S,8R,8aR)-4-hydroxy-5-(hydroxymethyl)-2,2,8-trimethyl-3,3a,4,5,8,8a-hexahydro-1H-azulene-6-carbaldehyde	14412874	Click to see	252.35	unknown	via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Ethers / Diarylethers
(11R,27R)-4,5,20,21-tetramethoxy-10,26-dimethyl-2,18-dioxa-10,26-diazaheptacyclo[27.2.2.13,7.113,17.119,23.011,36.027,34]hexatriaconta-1(32),3(36),4,6,13(35),14,16,19(34),20,22,29(33),30-dodecaene	53486320	Click to see	622.70	unknown	via CMAUP database

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Stephania delavayi

Table of Contents

Details Top

Ethnobotanical Use Top

General Uses Top

Synonyms Top

Common names Top

Subspecies (abbr. subsp./ssp.) Top

Varieties (abbr. var.) Top

Subvarieties (abbr. subvar.) Top

Forms (abbr. f.) Top

Germination/Propagation Top

Distribution (via POWO/KEW) Top

Links to other databases Top

Genomes (via NCBI) Top

Scientific Literature Top

Phytochemical Profile Top

Gallery Top

Contributors Top

Collections Top