Pachygone ovata
Details Top
| Internal ID | UUID644058f2a939c949648121 |
| Scientific name | Pachygone ovata |
| Authority | (Poir.) Diels |
| First published in | Pflanzenr. IV.94(Heft 46): 243 1910 |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
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Ethnobotanical Uses
Across southern India and Sri Lanka, decoctions and infusions of the root bark have long been prepared for diarrhoea and dysentery. The same bark was taken in early-twentieth-century India as a febrifuge and bitter tonic, while crushed leaves or bark were applied topically as poultices for bruises, sprains, and rheumatic pain. Regional accounts note the seed-bearing fruits as emetic and purgative in some folk practices. References: Indian Materia Medica (1938) and The Wealth of India (Raw Materials, 1962). Southeast Asian practices in Thailand and Malaysia recorded root decoctions for similar bowel complaints and fever, with occasional external poultices for injuries. References: Chakrapani 1928; Choo et al. 1989.
In Classical Chinese Medicine the plant is known as zhixiemu (止泻木) and the root bark is decocted, often with jujube or licorice, to “drain damp heat and stop dysentery.” Modern Chinese herbal references describe it as bitter and cold, suppressing pathogenic “damp-heat” in the large intestine and useful for damp-heat dysentery. References: Shanghai Science & Technology Press Chinese Materia Medica Dictionary (1998); Shanghai College of Traditional Medicine Chinese Materia Medica (1983). In Ayurvedic tradition the root bark has been used as a bitter tonic and fever reducer, with small decoctions taken for diarrhoea; seed or fruit infusions were occasionally taken as emetics. References: Indian Materia Medica (1938); The Wealth of India (Raw Materials, 1962).
A practical preparation is a mild root-bark decoction: simmer 10–15 g of chopped dried bark in 750 ml of water for 20–30 minutes, cool, strain, and drink 150–200 ml twice daily. Because the plant contains isoquinoline alkaloids, avoid larger or repeated doses, do not use during pregnancy or lactation, and discontinue if nausea or dizziness appears. Children should not receive this preparation.
The bitter bark’s action is plausibly linked to the presence of bisbenzylisoquinoline and other aporphine alkaloids, with coumarins and alkaloids also reported. While in vivo clinical trials remain scarce, extracts are actively studied for antimicrobial and antispasmodic activity, and the plant is still carried by Asian herbal suppliers and used in continuing traditional practice. References: The Wealth of India (Raw Materials, 1962); Choo et al. 1989; Shanghai Science & Technology Press Chinese Materia Medica Dictionary (1998).
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Limacia nativitatis | Ridl. | J. Straits Branch Roy. Asiat. Soc. 45: 170 (1906) |
| Menispermum leptostachyon | Spreng. | Syst. Veg. 2: 157 (1825) |
| Menispermum brachystachyon | Spreng. | Syst. Veg. 2: 157 (1825) |
| Tristichocalyx pubescens | F.Muell. | Fragm. 4: 27 (1863) |
| Tinospora hullsii | F.Muell. | Fragm. 5: 147 (1866) |
| Pachygone brachystachys | Miers | Ann. Mag. Nat. Hist. , ser. 2, 7: 43 (1851) |
| Pachygone adversa | Miers | Ann. Mag. Nat. Hist. , ser. 3, 14: 321 (1867) |
| Pachygone pubescens | Benth. | Fl. Austral. 1: 58 (1863) |
| Pachygone wightiana | Miers | Ann. Mag. Nat. Hist. , ser. 2, 7: 43 (1851) |
| Pachygone concinna | Miers | Ann. Mag. Nat. Hist. , ser. 3, 14: 321 (1867) |
| Pachygone hebephylla | Miers | Ann. Mag. Nat. Hist. , ser. 3, 14: 321 (1867) |
| Pachygone laevigata | Zippel ex Diels | Pflanzenr. , IV, 94: 244 (1910) |
| Pachygone leptostachys | Miers | Ann. Mag. Nat. Hist. , ser. 2, 7: 43 (1851) |
| Pachygone hullsii | F.Muell. | Fragm. 9: 81 (1875) |
| Cebatha pubescens | (F.Muell.) Kuntze | Revis. Gen. Pl. 1: 9 (1891) |
| Cissampelos ovata | Poir. | Encycl. 5: 10 (1804) |
| Cocculus brachystachyus | DC. | Syst. Nat. 1: 528 (1817) |
| Cocculus leptostachyus | DC. | Syst. Nat. 1: 528 (1817) |
| Cocculus plukenetii | DC. | Syst. Nat. 1: 520 (1817) |
| Pachygone plukenetii | Miers | Ann. Mag. Nat. Hist. , ser. 2, 7: 43 (1851) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| Tamil | கட்டுக்கொடி |
Germination/Propagation Top
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No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
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Asia-tropical click to expand
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Indian Subcontinent
- India
- Sri Lanka
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Indo-China
- Myanmar
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Malesia
- Borneo
- Christmas Island
- Jawa
- Lesser Sunda Islands
- Maluku
- Sulawesi
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Papuasia
- New Guinea
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Indian Subcontinent
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Australasia click to expand
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Australia
- Northern Territory
- Queensland
- Western Australia
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Australia
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0001273802 |
| UNII | 0058X7264T |
| Tropicos | 50267236 |
| KEW | urn:lsid:ipni.org:names:581224-1 |
| The Plant List | tro-50267236 |
| Open Tree Of Life | 628584 |
| Observations.org | 341025 |
| NCBI Taxonomy | 461616 |
| IPNI | 581224-1 |
| iNaturalist | 369579 |
| GBIF | 7268715 |
| Elurikkus | 580704 |
| USDA GRIN | 418434 |
| Wikipedia | Pachygone_ovata |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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| Title | Authors | Publication | Released | IDs | ||||||
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| Targeting Akt/NF-κB/p53 Pathway and Apoptosis Inducing Potential of 1,2-Benzenedicarboxylic Acid, Bis (2-Methyl Propyl) Ester Isolated from Onosma bracteata Wall. against Human Osteosarcoma (MG-63) Cells | Kumar A, Kaur S, Dhiman S, Singh PP, Bhatia G, Thakur S, Tuli HS, Sharma U, Kumar S, Almutary AG, Alnuqaydan AM, Hussain A, Haque S, Dhama K, Kaur S | Molecules | 28-May-2022 |
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| Ultramafic geoecology of South and Southeast Asia | Galey ML, van der Ent A, Iqbal MC, Rajakaruna N | Bot Stud | 03-Apr-2017 |
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| Ethnomedicinal studies on plants used by Yanadi tribe of Chandragiri reserve forest area, Chittoor District, Andhra Pradesh, India | Savithramma N, Yugandhar P, Prasad KS, Ankanna S, Chetty KM | J Intercult Ethnopharmacol | 27-Jan-2016 |
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| Alkaloids of Pachygone pubescens (Menispermaceae) | NK Hart, SR Johns, JA Lamberton, H Suares | CSIRO Publishing | 02-Sep-2010 |
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| Pachygonamine and N-Methylpachygonamine, New Bisbenzylisoquinoline Alkaloids from Pachygone ovata | Paul L. Schiff, Jr., M. Uvais S. Sultanbawa, Subramaniam Sotheeswaran, Sinnathamby Balasubramaniam, Moustafa Abd El-Kawi, David J. Slatkin | The Japan Institute of Heterocyclic Chemistry | 02-Mar-2009 |
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| Structure of Pachygonine, A New Quaternary Alkaloid From Pachygone ovata | S. V. Bhat, H. Dornauer, N. J. de Souza | American Chemical Society (ACS) | 17-Mar-2005 |
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| Constituents of Pachygone ovata and Pharmacological Action of its Major Leaf Alkaloid | S. Dasgupta, A. B. Ray, S. K. Bhattacharya, R. Bose | American Chemical Society (ACS) | 17-Mar-2005 |
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| Pachyovatamine, a bisbenzylisoquinoline alkaloid, and other alkaloids from Pachygone ovata | M. Uvais, S. Sultanbawa, Subramaniam Sotheeswaran, Sinnathamby Balasubramaniam, Moustafa Abd El-kawi, David J. Slatkin, Paul L. Schiff | Elsevier BV | 25-Jul-2002 |
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| Triterpenoid saponins from Ardisia crenata and their inhibitory activity on cAMP phosphodiesterase. | Jia Z, Koike K, Nikaido T, Ohmoto T, Ni M | Chem Pharm Bull (Tokyo) | 01-Nov-1994 |
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| Additional alkaloids of Pachygone ovata. | El-Kawi MA, Slatkin DJ, Schiff PL Jr, Dasgupta S, Chattopadhyay SK, Ray AB | J Nat Prod | 01-May-1984 |
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Phytochemical Profile Top
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Collections Top
| In private collections | 0 |
| In public collections | 0 |