Norjuziphine, (+-)-

Details

• Internal ID: 1b9931e5-6095-44ee-a0a1-bf9fc3e765ed
• Taxonomy: Organoheterocyclic compounds > Isoquinolines and derivatives > Benzylisoquinolines
• IUPAC Name: 1-[(4-hydroxyphenyl)methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-8-ol
• InChI: InChI=1S/C17H19NO3/c1-21-15-7-4-12-8-9-18-14(16(12)17(15)20)10-11-2-5-13(19)6-3-11/h2-7,14,18-20H,8-10H2,1H3
• InChI Key: BXWMZVREXWPYKF-UHFFFAOYSA-N
• Popularity: 10 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₇H₁₉NO₃
• Molecular Weight: 285.34 g/mol
• Exact Mass: 285.13649347 g/mol
• Topological Polar Surface Area (TPSA): 61.70 Ų
• XlogP: 2.60

Synonyms

• Norjuziphine, (+/-)-
• Norjuziphine
• 77N461426O
• UNII-77N461426O
• 8-Isoquinolinol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-7-methoxy-, (+/-)-
• 82373-01-1
• 74119-87-2

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	98.36%	96.09%
CHEMBL4203	Q9HAZ1	Dual specificity protein kinase CLK4	95.12%	94.45%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	93.89%	91.11%
CHEMBL3137262	O60341	LSD1/CoREST complex	93.25%	97.09%
CHEMBL5608	Q16288	NT-3 growth factor receptor	92.00%	95.89%
CHEMBL1907603	Q05586	Glutamate NMDA receptor; GRIN1/GRIN2B	91.88%	95.89%
CHEMBL2581	P07339	Cathepsin D	91.37%	98.95%
CHEMBL3060	Q9Y345	Glycine transporter 2	90.61%	99.17%
CHEMBL3192	Q9BY41	Histone deacetylase 8	89.87%	93.99%
CHEMBL2635	P51452	Dual specificity protein phosphatase 3	88.08%	94.00%
CHEMBL241	Q14432	Phosphodiesterase 3A	87.39%	92.94%
CHEMBL5852	Q96P65	Pyroglutamylated RFamide peptide receptor	85.29%	85.00%
CHEMBL3091268	Q92753	Nuclear receptor ROR-beta	84.34%	95.50%
CHEMBL1293249	Q13887	Kruppel-like factor 5	83.03%	86.33%
CHEMBL2535	P11166	Glucose transporter	80.99%	98.75%
CHEMBL2274	Q9H228	Sphingosine 1-phosphate receptor Edg-8	80.59%	100.00%

Plants that contains it

• Artabotrys brachypetalus
• Corydalis balansae
• Corydalis bulleyana
• Fumaria parviflora
• Fumaria vaillantii
• Neolitsea dealbata
• Ocotea lancifolia
• Pachygone ovata
• Phoebe formosana
• Porcelia macrocarpa
• Stephania cephalantha

Cross-Links

• PubChem: 21635162
• LOTUS: LTS0092647
• wikiData: Q104394484