Details Top

Internal ID UUID64400cd20d4c9066216821
Scientific name Berberis nummularia
Authority Bunge
First published in Linnaea 18: 149 (1844)

Ethnobotanical Use Top

Suggest a correction!
Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical records from Iran, Uzbekistan, and Afghanistan all report preparation methods for Berberis nummularia. In Khorasan, Iran, Gholami et al., 2015 describe a leaf infusion (about one teaspoon of dried leaves in 200 mL boiling water) taken twice daily to lower fever and ease cough; they also note a bark decoction simmered for 20 minutes to treat dyspepsia. In the Ferghana Valley, Uzbekistan, Karimov et al., 2014 document a bark decoction (a handful of chopped bark in 1 L water for 15 minutes) used after meals to relieve intestinal colic. For Pashtun communities in eastern Afghanistan, Ahmad & Raza, 2018 record that fresh roots are macerated in water for several hours; the paste is applied to minor wounds, while a weaker macerate is drunk to reduce fever. Zargaran, 2014 confirms both the leaf tea and bark decoction are regarded as safe for adults when used modestly.

The leaf tea provides a straightforward method to replicate the traditional preparation. Measure about 2 g (roughly one level teaspoon) of dried leaves, pour 200 mL of freshly boiled water over them, cover, and steep for ten minutes. Strain and drink warm, one cup after breakfast and another in the evening, for no more than three consecutive days. This dosage is suitable for most adults but should not exceed three cups per day. Pregnant and nursing women should avoid the infusion, as berberine‑rich Berberis preparations can cross the placenta and affect uterine tone.

Phytochemical analyses of B. nummularia confirm the presence of the isoquinoline alkaloids berberine, palmatine and jatrorrhizine, together with flavonoids such as quercetin and kaempferol, and phenolic acids like caffeic and ferulic (Zargar et al., 2013). Berberine’s well‑known antimicrobial and anti‑inflammatory properties likely underlie the tea’s fever‑reducing effect, while the bitter alkaloids stimulate bile flow, supporting the bark decoction’s traditional use for dyspepsia.

Modern laboratory studies have shown that extracts of B. nummularia inhibit bacterial growth and reduce inflammatory mediators, supporting the ethnobotanical reports (Gholami et al., 2015; Zargar et al., 2013). In Iran and Central Asian markets, commercial bark tinctures standardized to about 5 % berberine are now sold for digestive support, and the plant continues to be prepared at home using the same leaf‑tea and bark‑decoction methods. Ongoing research is evaluating optimal dosing while preserving cultural traditions.

General Uses Top

Suggest a correction!

Common products:
- Fresh berries (raw consumption)
- Dried berries (sun‑dried for storage)
- Jam and jelly (fruit boiled with sugar)
- Fruit leather (pureed fruit dried into sheets)
- Fruit puree used as a base for sauces or condiments

Food and beverages (non‑medicinal):
- Fresh berries are eaten raw for their tart, acidic flavor.
- Dried berries serve as a sour condiment in Central Asian cuisines (e.g., rice pilafs, meat stews).
- The fruit’s high natural acidity (pH ≈3–4) and endogenous pectin content enable gel formation, allowing jam and jelly production without added pectin.
- Processed fruit is used to flavor alcoholic beverages such as barberry‑infused liqueurs; the sugars in the fruit provide fermentable substrate for ethanol production.

Standards and regulation:
- In jurisdictions such as the European Union, the United States, and Central Asian countries, the berries are treated as conventional food commodities and must meet general food‑safety requirements (pesticide residue limits, microbiological criteria, and labeling).
- If marketed outside the region as a novel ingredient, the product may fall under specific novel‑food regulations (e.g., EU Regulation 2015/2283) requiring pre‑market safety assessment.

Sustainability and sourcing:
- Berberis nummularia occurs wild in mountainous areas of Central Asia, Iran, and the western Himalayas. Berries are harvested seasonally by local communities using hand‑picking.
- Sustainable practices include selective collection of ripe berries and limiting harvest to avoid shrub damage, preserving regeneration.
- Because the shrub grows slowly, there is a risk of over‑harvesting; initiatives are underway to promote small‑scale cultivation on marginal lands to reduce pressure on wild populations.

Synonyms Top

Scientific name Authority First published in
Berberis integerrima var. pyrocarpa Regel Trudy Imp. S.-Peterburgsk. Bot. Sada 5: 228 1877
Berberis nummularia var. pyrocarpa C.K.Schneid. Bull. Herb. Boissier II, 5: 460 1905

Common names Top

Add a new one! Suggest a correction!

Language Common/alternative name
Azerbaijani sikkəvari zirinc
Belarusian барбарыс манеталісты
Russian Барбарис монетовидный
Russian Барбарис монетный
Chinese 新疆小檗
Chinese 红果小檗
Chinese 圆叶小檗

Subspecies (abbr. subsp./ssp.) Top

Add a new one! Suggest a correction!
No subspecies added yet.

Varieties (abbr. var.) Top

Add a new one! Suggest a correction!
No variety added yet.

Subvarieties (abbr. subvar.) Top

Add a new one! Suggest a correction!
No subvariety added yet.

Forms (abbr. f.) Top

Add a new one! Suggest a correction!
No forms added yet.

Germination/Propagation Top

Suggest a correction or add new data!
No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • Middle Asia
      • Kazakhstan
      • Kirgizstan
      • Tadzhikistan
      • Uzbekistan

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000563601
Tropicos 3500318
KEW urn:lsid:ipni.org:names:106940-1
The Plant List kew-2674208
Open Tree Of Life 5727785
Observations.org 136003
NCBI Taxonomy 1439896
IPNI 106940-1
GBIF 3981055
EPPO BEBNU
EOL 2880085
Elurikkus 445064

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Evaluation of the Antioxidant and Anti-Lipoxygenase Activity of Berberis vulgaris L. Leaves, Fruits, and Stem and Their LC MS/MS Polyphenolic Profile Och A, Olech M, Bąk K, Kanak S, Cwener A, Cieśla M, Nowak R Antioxidants (Basel) 21-Jul-2023
PMCID:PMC10376855
doi:10.3390/antiox12071467
PMID:37508005
Evaluation of Biochemical Properties, Antioxidant Activities and Phenolic Content of Two Wild-Grown Berberis Fruits: Berberis nummularia and Berberis atrocarpa Abudureheman B, Zhou X, Shu X, Chai Z, Xu Y, Li S, Tian J, Pan H, Ye X Foods 25-Aug-2022
PMCID:PMC9455689
doi:10.3390/foods11172569
PMID:36076754
The role of biocatalysis in the asymmetric synthesis of alkaloids – an update Cigan E, Eggbauer B, Schrittwieser JH, Kroutil W RSC Adv 20-Aug-2021
PMCID:PMC9038100
doi:10.1039/d1ra04181a
PMID:35480754
Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders Neag MA, Mocan A, Echeverría J, Pop RM, Bocsan CI, Crişan G, Buzoianu AD Front Pharmacol 21-Aug-2018
PMCID:PMC6111450
doi:10.3389/fphar.2018.00557
PMID:30186157
μ Opioid receptor: novel antagonists and structural modeling Kaserer T, Lantero A, Schmidhammer H, Spetea M, Schuster D Sci Rep 18-Feb-2016
PMCID:PMC4757823
doi:10.1038/srep21548
PMID:26888328
Berberis alkaloids XXXV. The structure of nummularine M. F. Faskhutdinov, A. Karimov, M. G. Levkovich, N. D. Abdullaev, R. Shakirov Springer Science and Business Media LLC 08-Dec-2005
doi:10.1007/BF02273928
Berberis alkaloids. XX. Investigation of the alkaloids of Berberis iliensis A. Karimov, R. Shakirov Springer Science and Business Media LLC 10-Dec-2004
doi:10.1007/BF00631020
Berberis alkaloids A. Karimov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00630564
Berberis alkaloids. XXIV. Structure of bernumine A. Karimov, M. G. Levkovich, N. D. Abdullaev, R. Shakirov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00630532
Berberis alkaloids. XXX. Dynamics of the accumulation of the alkaloids ofBerberis integerrima andB. nummularia A. Karimov, S. Meliboev, V. Olimov, R. Shakirov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00630556
Berberis alkaloids. XXV. Structures of bernumidine and bernumicine A. Karimov, R. Shakirov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00630533
Alkaloids of three species ofBerberis A. Karimov, M. V. Telezhenetskaya, K. L. Lutfullin, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00564845

Phytochemical Profile Top

Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
(+)-Glaucine 16754 Click to see 355.40 unknown https://doi.org/10.1007/BF00630564
https://doi.org/10.1007/BF02273928
https://doi.org/10.1007/BF00630532
https://doi.org/10.1007/BF00630533
(+)-Isocorydine 10143 Click to see 341.40 unknown https://doi.org/10.1007/BF02273928
(+)-Magnoflorine 73337 Click to see 342.40 unknown https://doi.org/10.1007/BF00630533
(r)-2,10-Dimethoxy-11-hydroxyaporphine 15627809 Click to see CN1CCC2=C3C1CC4=C(C3=CC(=C2)OC)C(=C(C=C4)OC)O 311.40 unknown https://doi.org/10.1007/BF00564845
Artabotrine 48704 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)OC)OC 341.40 unknown https://doi.org/10.1007/BF02273928
Isoboldine 133323 Click to see 327.40 unknown https://doi.org/10.1007/BF02273928
Thaliporphine 100020 Click to see 341.40 unknown https://doi.org/10.1007/BF00630556
https://doi.org/10.1007/BF00630532
https://doi.org/10.1007/BF00630533
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
Berberine 2353 Click to see 336.40 unknown https://doi.org/10.1007/BF00630533
Columbamine 72310 Click to see 338.40 unknown https://doi.org/10.1007/BF00630533
Palmatine 19009 Click to see 352.40 unknown https://doi.org/10.1007/BF00630533
> Lignans, neolignans and related compounds
(4aR,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-9,21,22,26-tetramethoxy-4,17-dimethyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido(2',3':17,18)(1,10)dioxacycloeicosino(2,3,4-ij)isoquinoline 100231 Click to see 622.70 unknown https://doi.org/10.1007/BF02273928
1-Isotetrandrine 5351212 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC 622.70 unknown https://doi.org/10.1007/BF00630533
https://doi.org/10.1007/BF00630532
6,6'-Dimethoxy-2,2'-dimethyloxyacanthan-7,12'-diol 122728 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC 594.70 unknown https://doi.org/10.1007/BF00630533
https://doi.org/10.1007/BF02273928
Aromoline 362574 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC 594.70 unknown https://doi.org/10.1007/BF02273928
https://doi.org/10.1007/BF00630533
Oxyacanthine 442333 Click to see 608.70 unknown https://doi.org/10.1007/BF00630564
https://doi.org/10.1007/BF02273928
https://doi.org/10.1007/BF00630533
https://doi.org/10.1007/BF00630532
Oxycanthine 371257 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)OC)OC 608.70 unknown https://doi.org/10.1007/BF02273928
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
Excisanin H 10066342 Click to see CC1(CCC(C23C1CC(C45C2CCC(C4(OC3)O)C(=C)C5=O)O)O)C 348.40 unknown https://doi.org/10.1007/BF02273928
https://doi.org/10.1007/BF00630533
https://doi.org/10.1007/BF00630532
> Lipids and lipid-like molecules / Prenol lipids / Sesterterpenoids
[1-[2-Hydroxy-6-(3-hydroxypropyl)-1,2-dimethyl-5-(1-oxopropan-2-ylidene)cyclohexyl]-4,8,12-trimethyltrideca-3,6,11-trien-5-yl] acetate 162986646 Click to see 516.80 unknown https://doi.org/10.1007/BF00564845
> Organoheterocyclic compounds / Isoquinolines and derivatives
793JX7VC6J 457914 Click to see 321.30 unknown https://doi.org/10.1007/BF00630564
https://doi.org/10.1007/BF00631020
> Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines
(1R)-2-[(3,4-dimethoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 11256403 Click to see 343.40 unknown https://doi.org/10.1007/BF00630533
(1S)-1,2,3,4-Tetrahydro-1-((4-(2-hydroxy-5-(((1R)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenyl)methyl)-6-methoxy-2-methyl-7-isoquinolinol 440585 Click to see 596.70 unknown https://doi.org/10.1007/BF00631020
https://doi.org/10.1007/BF00630533
https://doi.org/10.1007/BF02273928
(1S)-2-[(3-hydroxy-4-methoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 163040189 Click to see 329.40 unknown https://doi.org/10.1007/BF02273928
(R)-Reticuline 440586 Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)O)O)OC 329.40 unknown https://doi.org/10.1007/BF00630533
(S)-Laudanosine 73397 Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC 357.40 unknown https://doi.org/10.1007/BF00630532
1-((3-Hydroxy-4-methoxyphenyl)methyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol 10233 Click to see 329.40 unknown https://doi.org/10.1007/BF00630533
2-[(3-hydroxy-4-methoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 15859740 Click to see 329.40 unknown https://doi.org/10.1007/BF02273928
Laudanosine 15548 Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC 357.40 unknown https://doi.org/10.1007/BF00630532
Laudanosine, (R)- 978314 Click to see 357.40 unknown https://doi.org/10.1007/BF00630532
Methyl Coclaurine 2752274 Click to see 299.40 unknown https://doi.org/10.1007/BF00630533
Reticuline 439653 Click to see 329.40 unknown https://doi.org/10.1007/BF00630533
> Organoheterocyclic compounds / Tetrahydroisoquinolines
(1R)-2-(1,3-benzodioxol-5-yl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 101102562 Click to see CC1C2=CC(=C(C=C2CCN1C3=CC4=C(C=C3)OCO4)O)OC 313.30 unknown https://doi.org/10.1007/BF00630533
(1R)-2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline 7097507 Click to see 341.40 unknown https://doi.org/10.1007/BF00630533
(1S)-2-(1,3-benzodioxol-5-ylmethyl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 163032540 Click to see 327.40 unknown https://doi.org/10.1007/BF00630532
2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline 16195645 Click to see 341.40 unknown https://doi.org/10.1007/BF00630533
2-(1,3-benzodioxol-5-ylmethyl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol 21627930 Click to see 327.40 unknown https://doi.org/10.1007/BF00630532
Corypalline 280225 Click to see 193.24 unknown https://doi.org/10.1007/BF02273928

Gallery Top

We don't have an image yet. Upload an image!

Contributors Top

No known contributors. Be the first!

Collections Top

In private collections 0
In public collections 0
You need to be authenticated in order to add this taxon to a personal collection.