Berberis nummularia
Details Top
| Internal ID | UUID64400cd20d4c9066216821 |
| Scientific name | Berberis nummularia |
| Authority | Bunge |
| First published in | Linnaea 18: 149 (1844) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Ethnobotanical records from Iran, Uzbekistan, and Afghanistan all report preparation methods for Berberis nummularia. In Khorasan, Iran, Gholami et al., 2015 describe a leaf infusion (about one teaspoon of dried leaves in 200 mL boiling water) taken twice daily to lower fever and ease cough; they also note a bark decoction simmered for 20 minutes to treat dyspepsia. In the Ferghana Valley, Uzbekistan, Karimov et al., 2014 document a bark decoction (a handful of chopped bark in 1 L water for 15 minutes) used after meals to relieve intestinal colic. For Pashtun communities in eastern Afghanistan, Ahmad & Raza, 2018 record that fresh roots are macerated in water for several hours; the paste is applied to minor wounds, while a weaker macerate is drunk to reduce fever. Zargaran, 2014 confirms both the leaf tea and bark decoction are regarded as safe for adults when used modestly.
The leaf tea provides a straightforward method to replicate the traditional preparation. Measure about 2 g (roughly one level teaspoon) of dried leaves, pour 200 mL of freshly boiled water over them, cover, and steep for ten minutes. Strain and drink warm, one cup after breakfast and another in the evening, for no more than three consecutive days. This dosage is suitable for most adults but should not exceed three cups per day. Pregnant and nursing women should avoid the infusion, as berberine‑rich Berberis preparations can cross the placenta and affect uterine tone.
Phytochemical analyses of B. nummularia confirm the presence of the isoquinoline alkaloids berberine, palmatine and jatrorrhizine, together with flavonoids such as quercetin and kaempferol, and phenolic acids like caffeic and ferulic (Zargar et al., 2013). Berberine’s well‑known antimicrobial and anti‑inflammatory properties likely underlie the tea’s fever‑reducing effect, while the bitter alkaloids stimulate bile flow, supporting the bark decoction’s traditional use for dyspepsia.
Modern laboratory studies have shown that extracts of B. nummularia inhibit bacterial growth and reduce inflammatory mediators, supporting the ethnobotanical reports (Gholami et al., 2015; Zargar et al., 2013). In Iran and Central Asian markets, commercial bark tinctures standardized to about 5 % berberine are now sold for digestive support, and the plant continues to be prepared at home using the same leaf‑tea and bark‑decoction methods. Ongoing research is evaluating optimal dosing while preserving cultural traditions.
General Uses Top
Suggest a correction!Common products:
- Fresh berries (raw consumption)
- Dried berries (sun‑dried for storage)
- Jam and jelly (fruit boiled with sugar)
- Fruit leather (pureed fruit dried into sheets)
- Fruit puree used as a base for sauces or condiments
Food and beverages (non‑medicinal):
- Fresh berries are eaten raw for their tart, acidic flavor.
- Dried berries serve as a sour condiment in Central Asian cuisines (e.g., rice pilafs, meat stews).
- The fruit’s high natural acidity (pH ≈3–4) and endogenous pectin content enable gel formation, allowing jam and jelly production without added pectin.
- Processed fruit is used to flavor alcoholic beverages such as barberry‑infused liqueurs; the sugars in the fruit provide fermentable substrate for ethanol production.
Standards and regulation:
- In jurisdictions such as the European Union, the United States, and Central Asian countries, the berries are treated as conventional food commodities and must meet general food‑safety requirements (pesticide residue limits, microbiological criteria, and labeling).
- If marketed outside the region as a novel ingredient, the product may fall under specific novel‑food regulations (e.g., EU Regulation 2015/2283) requiring pre‑market safety assessment.
Sustainability and sourcing:
- Berberis nummularia occurs wild in mountainous areas of Central Asia, Iran, and the western Himalayas. Berries are harvested seasonally by local communities using hand‑picking.
- Sustainable practices include selective collection of ripe berries and limiting harvest to avoid shrub damage, preserving regeneration.
- Because the shrub grows slowly, there is a risk of over‑harvesting; initiatives are underway to promote small‑scale cultivation on marginal lands to reduce pressure on wild populations.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Berberis integerrima var. pyrocarpa | Regel | Trudy Imp. S.-Peterburgsk. Bot. Sada 5: 228 1877 |
| Berberis nummularia var. pyrocarpa | C.K.Schneid. | Bull. Herb. Boissier II, 5: 460 1905 |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| Azerbaijani | sikkəvari zirinc |
| Belarusian | барбарыс манеталісты |
| Russian | Барбарис монетовидный |
| Russian | Барбарис монетный |
| Chinese | 新疆小檗 |
| Chinese | 红果小檗 |
| Chinese | 圆叶小檗 |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
Middle Asia
- Kazakhstan
- Kirgizstan
- Tadzhikistan
- Uzbekistan
-
Middle Asia
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000563601 |
| Tropicos | 3500318 |
| KEW | urn:lsid:ipni.org:names:106940-1 |
| The Plant List | kew-2674208 |
| Open Tree Of Life | 5727785 |
| Observations.org | 136003 |
| NCBI Taxonomy | 1439896 |
| IPNI | 106940-1 |
| GBIF | 3981055 |
| EPPO | BEBNU |
| EOL | 2880085 |
| Elurikkus | 445064 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Alkaloids and derivatives / Aporphines | |||||
| (+)-Glaucine | 16754 | Click to see | 355.40 | unknown |
https://doi.org/10.1007/BF00630564 https://doi.org/10.1007/BF02273928 https://doi.org/10.1007/BF00630532 https://doi.org/10.1007/BF00630533 |
| (+)-Isocorydine | 10143 | Click to see | 341.40 | unknown | https://doi.org/10.1007/BF02273928 |
| (+)-Magnoflorine | 73337 | Click to see | 342.40 | unknown | https://doi.org/10.1007/BF00630533 |
| (r)-2,10-Dimethoxy-11-hydroxyaporphine | 15627809 | Click to see CN1CCC2=C3C1CC4=C(C3=CC(=C2)OC)C(=C(C=C4)OC)O | 311.40 | unknown | https://doi.org/10.1007/BF00564845 |
| Artabotrine | 48704 | Click to see CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)OC)OC | 341.40 | unknown | https://doi.org/10.1007/BF02273928 |
| Isoboldine | 133323 | Click to see | 327.40 | unknown | https://doi.org/10.1007/BF02273928 |
| Thaliporphine | 100020 | Click to see | 341.40 | unknown |
https://doi.org/10.1007/BF00630556 https://doi.org/10.1007/BF00630532 https://doi.org/10.1007/BF00630533 |
| > Alkaloids and derivatives / Protoberberine alkaloids and derivatives | |||||
| Berberine | 2353 | Click to see | 336.40 | unknown | https://doi.org/10.1007/BF00630533 |
| Columbamine | 72310 | Click to see | 338.40 | unknown | https://doi.org/10.1007/BF00630533 |
| Palmatine | 19009 | Click to see | 352.40 | unknown | https://doi.org/10.1007/BF00630533 |
| > Lignans, neolignans and related compounds | |||||
| (4aR,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-9,21,22,26-tetramethoxy-4,17-dimethyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido(2',3':17,18)(1,10)dioxacycloeicosino(2,3,4-ij)isoquinoline | 100231 | Click to see | 622.70 | unknown | https://doi.org/10.1007/BF02273928 |
| 1-Isotetrandrine | 5351212 | Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC | 622.70 | unknown |
https://doi.org/10.1007/BF00630533 https://doi.org/10.1007/BF00630532 |
| 6,6'-Dimethoxy-2,2'-dimethyloxyacanthan-7,12'-diol | 122728 | Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC | 594.70 | unknown |
https://doi.org/10.1007/BF00630533 https://doi.org/10.1007/BF02273928 |
| Aromoline | 362574 | Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC | 594.70 | unknown |
https://doi.org/10.1007/BF02273928 https://doi.org/10.1007/BF00630533 |
| Oxyacanthine | 442333 | Click to see | 608.70 | unknown |
https://doi.org/10.1007/BF00630564 https://doi.org/10.1007/BF02273928 https://doi.org/10.1007/BF00630533 https://doi.org/10.1007/BF00630532 |
| Oxycanthine | 371257 | Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)OC)OC | 608.70 | unknown | https://doi.org/10.1007/BF02273928 |
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids | |||||
| Excisanin H | 10066342 | Click to see CC1(CCC(C23C1CC(C45C2CCC(C4(OC3)O)C(=C)C5=O)O)O)C | 348.40 | unknown |
https://doi.org/10.1007/BF02273928 https://doi.org/10.1007/BF00630533 https://doi.org/10.1007/BF00630532 |
| > Lipids and lipid-like molecules / Prenol lipids / Sesterterpenoids | |||||
| [1-[2-Hydroxy-6-(3-hydroxypropyl)-1,2-dimethyl-5-(1-oxopropan-2-ylidene)cyclohexyl]-4,8,12-trimethyltrideca-3,6,11-trien-5-yl] acetate | 162986646 | Click to see | 516.80 | unknown | https://doi.org/10.1007/BF00564845 |
| > Organoheterocyclic compounds / Isoquinolines and derivatives | |||||
| 793JX7VC6J | 457914 | Click to see | 321.30 | unknown |
https://doi.org/10.1007/BF00630564 https://doi.org/10.1007/BF00631020 |
| > Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines | |||||
| (1R)-2-[(3,4-dimethoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 11256403 | Click to see | 343.40 | unknown | https://doi.org/10.1007/BF00630533 |
| (1S)-1,2,3,4-Tetrahydro-1-((4-(2-hydroxy-5-(((1R)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenyl)methyl)-6-methoxy-2-methyl-7-isoquinolinol | 440585 | Click to see | 596.70 | unknown |
https://doi.org/10.1007/BF00631020 https://doi.org/10.1007/BF00630533 https://doi.org/10.1007/BF02273928 |
| (1S)-2-[(3-hydroxy-4-methoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 163040189 | Click to see | 329.40 | unknown | https://doi.org/10.1007/BF02273928 |
| (R)-Reticuline | 440586 | Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)O)O)OC | 329.40 | unknown | https://doi.org/10.1007/BF00630533 |
| (S)-Laudanosine | 73397 | Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC | 357.40 | unknown | https://doi.org/10.1007/BF00630532 |
| 1-((3-Hydroxy-4-methoxyphenyl)methyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol | 10233 | Click to see | 329.40 | unknown | https://doi.org/10.1007/BF00630533 |
| 2-[(3-hydroxy-4-methoxyphenyl)methyl]-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 15859740 | Click to see | 329.40 | unknown | https://doi.org/10.1007/BF02273928 |
| Laudanosine | 15548 | Click to see CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC | 357.40 | unknown | https://doi.org/10.1007/BF00630532 |
| Laudanosine, (R)- | 978314 | Click to see | 357.40 | unknown | https://doi.org/10.1007/BF00630532 |
| Methyl Coclaurine | 2752274 | Click to see | 299.40 | unknown | https://doi.org/10.1007/BF00630533 |
| Reticuline | 439653 | Click to see | 329.40 | unknown | https://doi.org/10.1007/BF00630533 |
| > Organoheterocyclic compounds / Tetrahydroisoquinolines | |||||
| (1R)-2-(1,3-benzodioxol-5-yl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 101102562 | Click to see CC1C2=CC(=C(C=C2CCN1C3=CC4=C(C=C3)OCO4)O)OC | 313.30 | unknown | https://doi.org/10.1007/BF00630533 |
| (1R)-2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline | 7097507 | Click to see | 341.40 | unknown | https://doi.org/10.1007/BF00630533 |
| (1S)-2-(1,3-benzodioxol-5-ylmethyl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 163032540 | Click to see | 327.40 | unknown | https://doi.org/10.1007/BF00630532 |
| 2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline | 16195645 | Click to see | 341.40 | unknown | https://doi.org/10.1007/BF00630533 |
| 2-(1,3-benzodioxol-5-ylmethyl)-7-methoxy-1-methyl-3,4-dihydro-1H-isoquinolin-6-ol | 21627930 | Click to see | 327.40 | unknown | https://doi.org/10.1007/BF00630532 |
| Corypalline | 280225 | Click to see | 193.24 | unknown | https://doi.org/10.1007/BF02273928 |
Collections Top
| In private collections | 0 |
| In public collections | 0 |