2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline

Details

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Internal ID 92ed02c7-524b-4265-8274-e86acaaeba80
Taxonomy Organoheterocyclic compounds > Tetrahydroisoquinolines
IUPAC Name 2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H23NO4/c1-13-16-10-19(23-3)18(22-2)9-15(16)6-7-21(13)11-14-4-5-17-20(8-14)25-12-24-17/h4-5,8-10,13H,6-7,11-12H2,1-3H3
InChI Key BSDPQEFENGLTDD-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C20H23NO4
Molecular Weight 341.40 g/mol
Exact Mass 341.16270821 g/mol
Topological Polar Surface Area (TPSA) 40.20 Ų
XlogP 3.40

Synonyms

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MLS001048918
CHEMBL1300835
CHEBI:114214
HMS2269J17
AKOS032435201
SMR000387109
Q27195478

2D Structure

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2D Structure of 2-(1,3-benzodioxol-5-ylmethyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.47% 96.09%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.56% 96.77%
CHEMBL2581 P07339 Cathepsin D 94.84% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 94.61% 93.40%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.92% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.66% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.19% 86.33%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 92.73% 91.43%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.92% 95.89%
CHEMBL3192 Q9BY41 Histone deacetylase 8 91.55% 93.99%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 91.24% 92.62%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 90.19% 97.31%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.41% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.00% 97.25%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 88.60% 95.89%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 88.17% 82.67%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 85.84% 90.95%
CHEMBL261 P00915 Carbonic anhydrase I 85.80% 96.76%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.11% 95.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.97% 94.00%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 83.68% 96.69%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.32% 99.17%
CHEMBL2413 P32246 C-C chemokine receptor type 1 83.08% 89.50%
CHEMBL5555 O00767 Acyl-CoA desaturase 81.21% 97.50%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 80.85% 95.78%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 80.83% 95.17%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.10% 92.94%
CHEMBL5747 Q92793 CREB-binding protein 80.09% 95.12%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 80.07% 94.80%
CHEMBL4208 P20618 Proteasome component C5 80.01% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Berberis nummularia

Cross-Links

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PubChem 16195645
LOTUS LTS0186137
wikiData Q27195478