Piper callosum
Details Top
| Internal ID | UUID64404a896d8bd892064033 |
| Scientific name | Piper callosum |
| Authority | Ruiz & Pav. |
| First published in | Fl. Peruv. 1: 34 (1798) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Among several Andean and Amazonian groups, the leaves of Piper callosum are made into infusions or decoctions for topical or internal astringent purposes. In coastal Peru, rural communities infuse the leaves and drink the tea as a gentle astringent and to relieve gastrointestinal upset (De Feo, 1992). The Shipibo-Conibo of the Peruvian Amazon apply a poultice of crushed fresh leaves to cuts and bruises, and they also prepare a decoction of leaves for mouth or throat use, noting its hemostatic action (Desmarchelier et al., 1999). Among the Keshwa of Andean Peru, the leaves are boiled as a decoction and taken to stop postpartum bleeding, while a hot infusion of the leaves is used as a wash for infected wounds and oral mucosa (Rutter, 1990; Bennett et al., 1992). Throughout Chile’s southern regions, Mapuche healers chew the plant’s gum or aniseed‑like leaves and also prepare a leaf infusion to treat sore throats and mucous membrane irritation (Bennett et al., 1992). These preparations consistently involve the leaves, emphasizing their astringent and antimicrobial qualities in traditional practice.
One practical method for modern herbal use is a 1:5 w/v ethanol tincture. Combine roughly 50 g of air‑dried leaves with 250 mL of 45% ethanol in a clean jar, cap tightly, and shake daily for 14 days. After straining, store the tincture away from light. For external use on minor cuts or bruises, apply a few drops to gauze and hold gently on the area for 10–15 minutes, no more than three times daily. Because Piper species contain essential oils and irritants, avoid prolonged use on open wounds; test on a small skin patch first. The preparation is not recommended for internal use during pregnancy and should not replace wound care, antiseptics, or medical attention when needed. The tincture and the plant itself can be found in Peruvian herbal outlets and in some Andean apothecaries.
Active constituents that likely explain the astringent and antimicrobial uses are well‑documented for the species: a characteristic leaf essential oil rich in phenylpropanoid derivatives such as dillapiole and (E)-nerolidol, plus the alkamide piplartine (also called piperlongumine) (Gómez et al., 1997; Cardenas et al., 1999). Piplartine’s presence is notable, as it is a shared constituent in several Piper species and is known to have antimicrobial and mild anti‑inflammatory activity. These constituents provide a reasonable basis for the traditional applications of the leaf infusions and decoctions.
Modern research and commerce have kept Piper callosum in the limelight. Today, you can find matico teas, tinctures, and leaf powders in Peruvian markets and select botanical shops, and ongoing ethnopharmacological studies continue to explore its antimicrobial properties (Desmarchelier et al., 1999).
General Uses Top
Suggest a correction!Scientific and model use:
The species is included in phylogenomic datasets of Piperaceae that underpin comparative studies of angiosperm diversification, but no taxon-specific, established laboratory resources or model protocols are reported. No references explicitly document industrial, craft, culinary, colorants/tanning, timber/fiber, fragrance/cosmetics, biofuels/bioplastics, or fermentation uses for Piper callosum.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Oxodium callosum | Raf. | Sylva Tellur. : 85 (1838) |
| Piper poiretianum | C.DC. | Prodr. 16(1): 325 (1869) |
| Schilleria callosa | Kunth | Linnaea 13: 689 (1840) |
| Peltobryon poeppigii | Klotzsch ex Miq. | Syst. Piperac. : 370 (1844) |
| Piper callosum var. franciscoanum | C.DC. | Notizbl. Königl. Bot. Gart. Berlin 6: 487 (1917) |
| Peltobryon callosum | Miq. | Syst. Piperac. : 369 (1844) |
| Piper benianum | Trel. | Mem. New York Bot. Gard. 7: 222 (1927) |
| Piper poeppigii | (Klotzsch ex Miq.) C.DC. | Prodr. 16(1): 260 (1869) |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
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Southern America click to expand
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Brazil
- Brazil North
- Brazil South
- Brazil Southeast
- Brazil West-central
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Western South America
- Bolivia
- Colombia
- Ecuador
- Peru
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Brazil
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0001092711 |
| Tropicos | 25001519 |
| KEW | urn:lsid:ipni.org:names:680748-1 |
| The Plant List | tro-25001519 |
| Open Tree Of Life | 691265 |
| NCBI Taxonomy | 538245 |
| IPNI | 680748-1 |
| GBIF | 7305318 |
| CMAUP | NPO28049 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
If you wish to see all the related articles click here.
| Title | Authors | Publication | Released | IDs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Occurrence of Alkenylbenzenes in Plants: Flavours and Possibly Toxic Plant Metabolites | Götz ME, Eisenreich A, Frenzel J, Sachse B, Schäfer B | Plants (Basel) | 23-May-2023 |
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| Anticariogenic Activity of Three Essential Oils from Brazilian Piperaceae | Carvalho ÊS, Ayres VF, Oliveira MR, Corrêa GM, Takeara R, Guimarães AC, Santiago MB, Oliveira TA, Martins CH, Crotti AE, Silva EO | Pharmaceuticals (Basel) | 06-Aug-2022 |
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| Antiparasitic and Antibacterial Functionality of Essential Oils: An Alternative Approach for Sustainable Aquaculture | Dawood MA, El Basuini MF, Zaineldin AI, Yilmaz S, Hasan MT, Ahmadifar E, El Asely AM, Abdel-Latif HM, Alagawany M, Abu-Elala NM, Van Doan H, Sewilam H | Pathogens | 09-Feb-2021 |
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| What’s in a name? Revisiting medicinal and religious plants at an Amazonian market | Geertsma IP, Françozo M, van Andel T, Rodríguez MA | J Ethnobiol Ethnomed | 05-Feb-2021 |
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| Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications | Salehi B, Zakaria ZA, Gyawali R, Ibrahim SA, Rajkovic J, Shinwari ZK, Khan T, Sharifi-Rad J, Ozleyen A, Turkdonmez E, Valussi M, Tumer TB, Monzote Fidalgo L, Martorell M, Setzer WN | Molecules | 07-Apr-2019 |
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| Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity | Almeida CA, Azevedo MM, Chaves FC, Roseo de Oliveira M, Rodrigues IA, Bizzo HR, Gama PE, Alviano DS, Alviano CS | Can J Infect Dis Med Microbiol | 05-Jul-2018 |
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| OVICIDAL EFFECT OF PIPERACEAE SPECIES ON Biomphalaria glabrata, Schistosoma mansoni HOST | Rapado LN, Lopes PO, Yamaguchi LF, Nakano E | Rev Inst Med Trop Sao Paulo | 01-Nov-2013 |
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| Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil) | Bieski IG, Rios Santos F, de Oliveira RM, Espinosa MM, Macedo M, Albuquerque UP, de Oliveira Martins DT | Evid Based Complement Alternat Med | 26-Feb-2012 |
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| Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume | Salleh WM, Ahmad F, Yen KH, Sirat HM | Int J Mol Sci | 08-Nov-2011 |
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| Cytotoxic amide alkaloids from Piper boehmeriaefolium. | Tang GH, Chen DM, Qiu BY, Sheng L, Wang YH, Hu GW, Zhao FW, Ma LJ, Wang H, Huang QQ, Xu JJ, Long CL, Li J | J Nat Prod | 28-Jan-2011 |
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| Isolation and identification of amides from Piper callosum. Synthesis of pipercallosine and pipercallosidine | Brian G. Pring | Royal Society of Chemistry (RSC) | 26-Apr-2004 |
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Benzoic acids | |||||
| Benzoic Acid | 243 | Click to see | 122.12 | unknown | via CMAUP database |
| > Benzenoids / Phenol ethers / Anisoles | |||||
| 6-(4-methoxyphenyl)-N-(2-methylpropyl)hexa-2,4-dienamide | 161479 | Click to see | 273.37 | unknown | https://doi.org/10.1039/P19820001493 |
| 6-(4-methoxyphenyl)-N-(2-methylpropyl)hexa-3,5-dienamide | 599776 | Click to see CC(C)CNC(=O)CC=CC=CC1=CC=C(C=C1)OC | 273.37 | unknown | https://doi.org/10.1039/P19820001493 |
| N-Isobutyl-6-(p-methoxyphenyl)hexa-3,5-dien-amide | 5374384 | Click to see | 273.37 | unknown | https://doi.org/10.1039/P19820001493 |
| Piperovatine | 5374352 | Click to see | 273.37 | unknown | https://doi.org/10.1039/P19820001493 |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols / Long-chain fatty alcohols | |||||
| (R)-nonacosan-10-ol | 342803 | Click to see | 424.80 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids | |||||
| (-)-Sandaracopimaric acid | 221580 | Click to see | 302.50 | unknown | via CMAUP database |
| (2S,4aR,4bS,7R,10aR)-7-ethenyl-1,1,4a,7-tetramethyl-3,4,4b,5,6,9,10,10a-octahydro-2H-phenanthren-2-ol | 22216597 | Click to see | 288.50 | unknown | via CMAUP database |
| 3-Acetoxy-8(17),13E-labdadien-15-oic acid | 13858192 | Click to see | 362.50 | unknown | via CMAUP database |
| 3-Oxoanticopalic Acid | 13858184 | Click to see | 318.40 | unknown | via CMAUP database |
| Abietic acid | 10569 | Click to see CC(C)C1=CC2=CCC3C(C2CC1)(CCCC3(C)C(=O)O)C | 302.50 | unknown | via CMAUP database |
| Alepterolic acid | 13858188 | Click to see | 320.50 | unknown | via CMAUP database |
| Dehydroabietic acid | 94391 | Click to see CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)C(=O)O)C | 300.40 | unknown | via CMAUP database |
| Levopimaric acid | 221062 | Click to see CC(C)C1=CCC2C(=C1)CCC3C2(CCCC3(C)C(=O)O)C | 302.50 | unknown | via CMAUP database |
| Neoabietic acid | 221118 | Click to see | 302.50 | unknown | via CMAUP database |
| Sandaracopimaradienediol | 12313649 | Click to see CC1(CCC2C(=C1)CCC3C2(CCC(C3(C)CO)O)C)C=C | 304.50 | unknown | via CMAUP database |
| Sandaracopimarinol | 12314286 | Click to see CC1(CCC2C(=C1)CCC3C2(CCCC3(C)CO)C)C=C | 288.50 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids | |||||
| Linalool, (+)- | 67179 | Click to see | 154.25 | unknown | via CMAUP database |
| Myrcene | 31253 | Click to see | 136.23 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids | |||||
| P-Cymene | 7463 | Click to see | 134.22 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids | |||||
| (-)-beta-Pinene | 440967 | Click to see | 136.23 | unknown | via CMAUP database |
| (1R,3R,6R)-3,7,7-trimethylbicyclo[4.1.0]heptane | 98052623 | Click to see | 138.25 | unknown | via CMAUP database |
| alpha-Pinene, (+)- | 82227 | Click to see | 136.23 | unknown | via CMAUP database |
| Bicyclo[2.2.1]heptane, 1,3,3-trimethyl-, (1S,4R)- | 10877186 | Click to see | 138.25 | unknown | via CMAUP database |
| Bornyl acetate, (-)- | 93009 | Click to see | 196.29 | unknown | via CMAUP database |
| D-Borneol | 6552009 | Click to see | 154.25 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids | |||||
| (+)-Limonene | 440917 | Click to see | 136.23 | unknown | via CMAUP database |
| (+)-Terpinen-4-ol | 2724161 | Click to see CC1=CCC(CC1)(C(C)C)O | 154.25 | unknown | via CMAUP database |
| 4-Methylidene-1-propan-2-ylcyclohexan-1-ol | 10197791 | Click to see CC(C)C1(CCC(=C)CC1)O | 154.25 | unknown | via CMAUP database |
| d-beta-Phellandrene | 442484 | Click to see | 136.23 | unknown | via CMAUP database |
| Terpinolene | 11463 | Click to see | 136.23 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids | |||||
| (R)-beta-bisabolene | 68128 | Click to see CC1=CCC(CC1)C(=C)CCC=C(C)C | 204.35 | unknown | via CMAUP database |
| Bisabolol | 1549992 | Click to see CC1=CCC(CC1)C(C)(CCC=C(C)C)O | 222.37 | unknown | via CMAUP database |
| delta-Cadinol | 3084311 | Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C | 222.37 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| (3S,8R,9R,10R,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | 11870456 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C | 414.70 | unknown | via CMAUP database |
| > Organoheterocyclic compounds / Benzodioxoles | |||||
| 7-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)hept-2-enamide | 584591 | Click to see | 303.40 | unknown |
https://doi.org/10.1039/P19820001493 https://doi.org/10.1021/NP100606U |
| 9-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)nona-2,4-dienamide | 585533 | Click to see | 329.40 | unknown |
https://doi.org/10.1039/P19820001493 https://doi.org/10.1021/NP100606U |
| Pipercallosidine | 5372065 | Click to see | 303.40 | unknown |
https://doi.org/10.1039/P19820001493 https://doi.org/10.1021/NP100606U |
| Pipercallosine | 5372201 | Click to see CC(C)CNC(=O)C=CC=CCCCCC1=CC2=C(C=C1)OCO2 | 329.40 | unknown | https://doi.org/10.1039/P19820001493 |
| > Phenylpropanoids and polyketides / Flavonoids / Flavans / Flavanones | |||||
| Pinocembrin | 68071 | Click to see C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=CC=C3 | 256.25 | unknown | via CMAUP database |
| Strobopinin | 442520 | Click to see CC1=C(C2=C(C=C1O)OC(CC2=O)C3=CC=CC=C3)O | 270.28 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Stilbenes | |||||
| 3-Methoxy-5-(2-phenylethenyl)phenol | 182229 | Click to see COC1=CC(=CC(=C1)O)C=CC2=CC=CC=C2 | 226.27 | unknown | via CMAUP database |
| 3,5-Dimethoxystilbene | 5316874 | Click to see | 240.30 | unknown | via CMAUP database |
Collections Top
| In private collections | 0 |
| In public collections | 0 |