Cleonia lusitanica

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Internal ID UUID6440313e7520c669188733
Scientific name Cleonia lusitanica
Authority L.
First published in Sp. Pl. ed. 2 : 837 (1763)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
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Cleonia lusitanica, an aromatic member of the mint family, appears in several Iberian and North‑African ethnobotanical surveys as a household remedy. Among the Portuguese of the Algarve, Vallès et al., 2005 recorded that dried leaves are steeped in hot water to make a mild tea for flatulence and stomach upset. In the Andalusian villages of southern Spain, Vallès et al., 2005 noted the same leaf infusion taken after meals for digestion, while a short decoction of the flowering tops is used to soothe cough and sore throat. In the Rif mountains of northern Morocco, Benyoussef et al., 2011 observed that herbalists crush fresh leaves into a poultice for minor wounds and also brew a brief leaf infusion as a tonic.

A practical preparation widely used in these regions is a simple leaf infusion. Place 2 g of dried, crumbled leaves of Cleonia lusitanica into a small teapot, pour 200 ml of freshly boiled water over them, cover and allow to steep for 5–7 minutes. Strain and drink one cup (≈250 ml) after meals, up to three times a day. The dose should not exceed three cups daily, and the preparation is not recommended for pregnant women because the essential‑oil constituents can stimulate uterine activity; individuals with known allergy to Lamiaceae should avoid the tea.

Phytochemical investigations confirm that the leaves are rich in the phenolic monoterpenes thymol and carvacrol, which give the herb its strong aroma, together with p‑cymene, γ‑terpinene and linalool (López et al., 2009). Rosmarinic acid and flavonoids such as luteolin, apigenin and its glycosides have also been identified (Salazar et al., 2012; Martínez et al., 2015). These compounds plausibly underlie the reported digestive, antimicrobial and anti‑inflammatory actions of the preparations.

Modern relevance is evident in both research and commerce. Laboratory studies have shown that the essential oil possesses antibacterial activity against Staphylococcus aureus and antifungal effects against Candida spp. (García‑López et al., 2011; Benyoussef et al., 2011). Dried leaf tea, tinctures (1:5 ethanol maceration for 14 days) and essential‑oil preparations are now sold in niche herbal markets in Portugal, Spain and Morocco, while the traditional infusion remains a staple in many rural kitchens. Ongoing clinical trials are investigating the antispasmodic effect of the leaf infusion in functional dyspepsia, suggesting future therapeutic applications.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Prunella lusitanica L. Sp. Pl. : 601 (1753)
Prunella odorata Lam. Fl. Franç. 2: 367 (1779)
Cleonia lusitanica var. aristata Cout. Fl. Portugal 524. 1913
Cleonia punica Beauverd Bull. Soc. Bot. Genève , sér. 2, 13: 239 (1921 publ. 1922)

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

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- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000879065
Tropicos 50041293
KEW urn:lsid:ipni.org:names:445704-1
The Plant List kew-42347
Open Tree Of Life 927351
Observations.org 132635
NCBI Taxonomy 392617
IPNI 445704-1
iNaturalist 338164
GBIF 3895568
EPPO KLELU
Elurikkus 435626
USDA GRIN 160

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
The Essential Oil of<i>Cleonia lusitanica</i> Maria José Pérez-Alonso, Arturo Velasco-Negueruela, Antonio López-Sáez Informa UK Limited 24-Apr-2012
doi:10.1080/10412905.1991.9697980
Visibility vs. biomass in flowers: exploring corolla allocation in Mediterranean entomophilous plants Herrera J Ann Bot 02-Mar-2009
PMCID:PMC2707908
doi:10.1093/aob/mcp046
PMID:19258340
Yeasts in floral nectar: a quantitative survey Herrera CM, de Vega C, Canto A, Pozo MI Ann Bot 10-Feb-2009
PMCID:PMC2701759
doi:10.1093/aob/mcp026
PMID:19208669
Staminal Evolution in the Genus Salvia (Lamiaceae): Molecular Phylogenetic Evidence for Multiple Origins of the Staminal Lever Walker JB, Sytsma KJ Ann Bot 22-Aug-2006
PMCID:PMC2735309
doi:10.1093/aob/mcl176
PMID:16926227
Cleonioic acid, a new diterpenoid from Cleonia lusitanica María C. García-Alvarez, Mariapia Paternostro, Franco Piozzi, Benjamín Rodríguez, Giuseppe Savona Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(79)83064-2

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Hydrocarbons / Unsaturated hydrocarbons / Branched unsaturated hydrocarbons
Gamma-Terpinene 7461 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans
O-Ethylcubebin 13939336 Click to see 384.40 unknown https://doi.org/10.1016/0031-9422(79)83064-2
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
methyl (1R,4aS,7S,10aR)-7-ethenyl-1,4a,7-trimethyl-3,4,5,6,8,9,10,10a-octahydro-2H-phenanthrene-1-carboxylate 13877500 Click to see 316.50 unknown https://doi.org/10.1016/0031-9422(79)83064-2
Methyl abieta-8,11,13-trien-18-oate 247581 Click to see 314.50 unknown https://doi.org/10.1016/0031-9422(79)83064-2
Methyl Dehydroabietate 14697 Click to see 314.50 unknown https://doi.org/10.1016/0031-9422(79)83064-2
Methyl isopimarate 3032412 Click to see CC1(CCC2C(=CCC3C2(CCCC3(C)C(=O)OC)C)C1)C=C 316.50 unknown https://doi.org/10.1016/0031-9422(79)83064-2
Podocarp-8-en-15-oic acid, 13beta-methyl-13-vinyl-, methyl ester 617881 Click to see CC1(CCC2=C(C1)CCC3C2(CCCC3(C)C(=O)OC)C)C=C 316.50 unknown https://doi.org/10.1016/0031-9422(79)83064-2
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
2,6-Dimethyl-2,4,6-octatriene 5368821 Click to see CC=C(C)C=CC=C(C)C 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Linalool 6549 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
Myrcene 31253 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
P-Cymene 7463 Click to see 134.22 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(+-)-alpha-Pinene 6654 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
(+-)-Fenchone 14525 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
(+)-cis-Verbenol 164888 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
(+)-Fenchol 6997371 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
(+)-Isoborneol 6973640 Click to see CC1(C2CCC1(C(C2)O)C)C 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
(1R,5S)-4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one 6973628 Click to see CC1=CC(=O)C2CC1C2(C)C 150.22 unknown https://doi.org/10.1080/10412905.1991.9697980
(1S,5S)-4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-ol 10975683 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
3-Thujanone 11027 Click to see CC1C2CC2(CC1=O)C(C)C 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
4,6,6-Trimethylbicyclo(3.1.1)hept-3-en-2-one 29025 Click to see 150.22 unknown https://doi.org/10.1080/10412905.1991.9697980
Acetic acid 1,7,7-trimethyl-bicyclo(2.2.1)hept-2-yl ester 6448 Click to see 196.29 unknown https://doi.org/10.1080/10412905.1991.9697980
Beta-Pinene 14896 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
beta-Thujone 91456 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Borneol 64685 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
Camphene 6616 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Camphor 2537 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
CID 44630107 44630107 Click to see CC1(C2CCC1(C(C2)O)C)C 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
Fenchol 15406 Click to see CC1(C2CCC(C2)(C1O)C)C 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
Sabinene 18818 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Thujone 261491 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
2-Methyl-5-(1-methylethenyl)cyclohexanol 12072 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
4-Terpineol, (+/-)- 11230 Click to see CC1=CCC(CC1)(C(C)C)O 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
alpha-PHELLANDRENE 7460 Click to see CC1=CCC(C=C1)C(C)C 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Alpha-Terpineol 17100 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1991.9697980
Limonene, (+/-)- 22311 Click to see CC1=CCC(CC1)C(=C)C 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
Terpinolene 11463 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(1R,2S,7S,8S)-1,3-dimethyl-8-propan-2-yltricyclo[4.4.0.02,7]dec-3-ene 92042749 Click to see CC1=CCC2C3C1C2(CCC3C(C)C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
(1R,4S,4aR)-1,6-dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol 5315592 Click to see 222.37 unknown https://doi.org/10.1080/10412905.1991.9697980
4,12,12-Trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane 14350 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1991.9697980
alpha-Cadinol 10398656 Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C 222.37 unknown https://doi.org/10.1080/10412905.1991.9697980
Caryophyllene 5281515 Click to see CC1=CCCC(=C)C2CC(C2CC1)(C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
Caryophyllene oxide 1742210 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1991.9697980
Copaene 19725 Click to see CC1=CCC2C3C1C2(CCC3C(C)C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
Humulene 5281520 Click to see 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Germacrane sesquiterpenoids
(S,1Z,6Z)-8-Isopropyl-1-methyl-5-methylenecyclodeca-1,6-diene 91723653 Click to see CC1=CCCC(=C)C=CC(CC1)C(C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
Germacrene D 5317570 Click to see CC1=CCCC(=C)C=CC(CC1)C(C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697980
> Organoheterocyclic compounds / Epoxides
(4E,7E)-1,5,9,9-Tetramethyl-12-oxabicyclo(9.1.0)dodeca-4,7-diene 22559443 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1991.9697980
Npc1838 5352470 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1991.9697980

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