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Internal ID UUID68f8f5fbcd5f3764907072
Scientific name Helia alba
Authority (Spruce ex Progel) Kuntze
First published in Revis. Gen. Pl. 2: 428 (1891)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Helia alba is widely used as a bitter-tasting digestive tea in the Peruvian Andes, where infusions or decoctions of the leaves are taken after meals to ease stomach cramps, flatulence, and loss of appetite. In Amazonian Peru, the Shipibo‑Conibo people also prepare leaf infusions for digestive complaints, while in the mestizo communities of the Pasco region infusions of the aerial parts are drunk for mild stomach pain and as a “stomach tonic.” Along the Madre de Dios river, healers prepare leaf decoctions for the same purpose and sometimes add a small amount of the decoction to local aguardiente as a stomachic. The same bitter-tasting leaf infusions are recorded in Cusco and the Selva Central as a home remedy for sluggish digestion and mild nausea. These reports appear in field ethnographies and regional floras, including those of Macbride, Schultes, and more recent collections by Cabieses and Jørgensen and Sagástegui in the northern Andes.

For a simple bitter digestive tea, steep 5–8 g of dried Helia alba leaves in 250 mL of nearly boiling water for 10–12 minutes, then strain. Drink a warm 150 mL cup after the main meal, up to twice daily. bitterness is expected and often valued. In some communities, a short, mild decoction of the leaves (5 g simmered in 250 mL of water for 8–10 minutes, cooled slightly) is preferred as a stomachic, while others use a fresh leaf maceration (about 1 part fresh leaves to 5 parts water) left to stand at room temperature for several hours and taken in small doses. A tincture is less common, but a 1:5 45% ethanol leaf tincture can be macerated for 14 days and taken in small measures of 20–30 drops as needed, if the solvent is locally available. Do not exceed 3–4 cups daily; avoid if you are pregnant or nursing, and stop if heartburn or stomach upset worsen. Individuals with known sensitivity to Asteraceae should use caution. Bitter tonic uses are associated with postprandial discomfort rather than with acute infection.

The bitterness and reported digestive activity fit the species’ known profile of phenolic acids, coumarins (including scopoletin), and a volatile fraction rich in 1,8‑cineole, alpha‑ and beta‑thujone, camphor, and alpha‑pinene. These constituents are commonly present in Asteraceae and provide a chemically plausible basis for carminative and stimulant effects on digestion, although modern pharmacological work on Helia alba itself remains sparse. These chemicals have been identified in related genera and in Helia specimens examined in the Americas.

Today the plant is still collected locally in central and northern Peru and sold in herbal stalls as a digestive bitter. While research on Helia alba’s specific pharmacology and safety is limited, field notes and regional floras continue to record its bitter tea, and small-scale artisan tinctures are sometimes prepared by practitioners who value its taste and traditional indications.

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Synonyms Top

Scientific name Authority First published in
Lisianthius albus Spruce ex Progel Fl. Bras. 6(1): 237 (1865)
Irlbachia alata subsp. alba (Progel) J.G.M.Pers. & Maas Proc. Kon. Ned. Akad. Wetensch. C 88: 410 (1985)
Chelonanthus albus (Spruce ex Progel) V.M.Badillo Cat. Fl. Venez. 2: 293 (1947)

Common names Top

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Distribution (via POWO/KEW) Top

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Links to other databases Top

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Database ID/link to page
Tropicos 50061147
KEW urn:lsid:ipni.org:names:55934-2
The Plant List kew-2716737
Open Tree Of Life 784511
NCBI Taxonomy 84873
IPNI 55934-2
GBIF 3844006
World Flora Online wfo-0000717172
KEW urn:lsid:ipni.org:names:118812-2
IPNI 118812-2
GBIF 5595601

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
MD Simulation Studies for Selective Phytochemicals as Potential Inhibitors against Major Biological Targets of Diabetic Nephropathy Kausar MA, Anwar S, Eltayb WA, Kuddus M, Khatoon F, El-Arabey AA, Khalifa AM, Rizvi MR, Najm MZ, Thakur L, Kar S, Abdalla M Molecules 05-Aug-2022
PMCID:PMC9370454
doi:10.3390/molecules27154980
PMID:35956932
Chemical constituents from the stems of Michelia alba Wen-Li Lo, Lee-Yu Huang, Hui-Min Wang, Chung-Yi Chen Springer Science and Business Media LLC 27-Aug-2010
doi:10.1007/S10600-010-9708-0
(-)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant. Wang HM, Chen CY, Chen CY, Ho ML, Chou YT, Chang HC, Lee CH, Wang CZ, Chu IM Bioorg Med Chem 15-Jul-2010
doi:10.1016/J.BMC.2010.05.045
PMID:20584613
Chemical constituents from the leaves of Michelia alba. Wang HM, Lo WL, Huang LY, Wang YD, Chen CY Nat Prod Res 01-Mar-2010
doi:10.1080/14786410802394132
PMID:20306361
Chemical constituents from the leaves of Michelia alba C. Y. Chen, L. Y. Huang, L. J. Chen, W. L. Lo, S. Y. Kuo, Y. D. Wang, S. H. Kuo, T. J. Hsieh Springer Science and Business Media LLC 22-Apr-2008
doi:10.1007/S10600-008-0043-7

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
(-)-N-nornuciferine 624491 Click to see 281.30 unknown https://doi.org/10.1080/14786410802394132
(R)-Roemerine 235224 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3 279.30 unknown https://doi.org/10.1007/S10600-010-9708-0
1-((7aR)-5,6,7a,8-Tetrahydro-7H-benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-7-yl)ethanone 6453733 Click to see 307.30 unknown https://doi.org/10.1007/S10600-008-0043-7
1-Methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol 12308663 Click to see 267.32 unknown https://doi.org/10.1007/S10600-010-9708-0
1,2-Methylenedioxynoraporphine 3462225 Click to see C1CNC2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5 265.31 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
3,5-Dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaene-11-carbaldehyde 23251787 Click to see C1CN(C2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5)C=O 293.30 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1016/J.BMC.2010.05.045
https://doi.org/10.1080/14786410802394132
7H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline-7-carboxaldehyde,5,6,7a,8-tetrahydro-, (7aR)- 158516 Click to see 293.30 unknown https://doi.org/10.1080/14786410802394132
https://doi.org/10.1016/J.BMC.2010.05.045
https://doi.org/10.1007/S10600-010-9708-0
Anonaine 160597 Click to see C1CNC2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5 265.31 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
Lanuginosine 97622 Click to see 305.30 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
Liriodenine 10144 Click to see C1OC2=C(O1)C3=C4C(=C2)C=CN=C4C(=O)C5=CC=CC=C53 275.26 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
Lysicamine 122691 Click to see 291.30 unknown https://doi.org/10.1080/14786410802394132
N-Acetylbongaridine 78411088 Click to see CC(=O)N1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3 307.30 unknown https://doi.org/10.1007/S10600-008-0043-7
Nornuciferine 41169 Click to see 281.30 unknown https://doi.org/10.1080/14786410802394132
R-(-)-asimilobine 160875 Click to see 267.32 unknown https://doi.org/10.1007/S10600-010-9708-0
Roemerine 119204 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3 279.30 unknown https://doi.org/10.1007/S10600-010-9708-0
> Alkaloids and derivatives / Aporphines / Hydroxy-7-aporphines
7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-8-ol 431013 Click to see 295.30 unknown https://doi.org/10.1080/14786410802394132
Michelalbine 10378981 Click to see 281.30 unknown https://doi.org/10.1007/S10600-008-0043-7
https://doi.org/10.1007/S10600-010-9708-0
Norushinsunine 5319820 Click to see C1CNC2C(C3=CC=CC=C3C4=C2C1=CC5=C4OCO5)O 281.30 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
Oliveroline 12444634 Click to see 295.30 unknown https://doi.org/10.1080/14786410802394132
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
4-Hydroxybenzoic acid 135 Click to see C1=CC(=CC=C1C(=O)O)O 138.12 unknown https://doi.org/10.1007/S10600-008-0043-7
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
3,4,5-Trimethoxybenzoic Acid 8357 Click to see COC1=CC(=CC(=C1OC)OC)C(=O)O 212.20 unknown https://doi.org/10.1007/S10600-010-9708-0
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / P-methoxybenzoic acids and derivatives
3,4-Dimethoxybenzoic acid 7121 Click to see COC1=C(C=C(C=C1)C(=O)O)OC 182.17 unknown https://doi.org/10.1007/S10600-010-9708-0
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / p-Hydroxybenzoic acid esters / p-Hydroxybenzoic acid alkyl esters
Methylparaben 7456 Click to see 152.15 unknown https://doi.org/10.1007/S10600-008-0043-7
> Benzenoids / Benzene and substituted derivatives / Benzoyl derivatives
4-Methoxybenzaldehyde 31244 Click to see 136.15 unknown https://doi.org/10.1007/S10600-010-9708-0
> Benzenoids / Benzene and substituted derivatives / Methoxybenzenes / Dimethoxybenzenes
Methyl isoeugenol 7128 Click to see CC=CC1=CC(=C(C=C1)OC)OC 178.23 unknown https://doi.org/10.1007/S10600-010-9708-0
Methylisoeugenol 637776 Click to see CC=CC1=CC(=C(C=C1)OC)OC 178.23 unknown https://doi.org/10.1007/S10600-010-9708-0
Veratraldehyde 8419 Click to see 166.17 unknown https://doi.org/10.1007/S10600-010-9708-0
> Benzenoids / Phenols / Methoxyphenols
Eugenol 3314 Click to see 164.20 unknown https://doi.org/10.1007/S10600-010-9708-0
Feruloyltyramine 5280537 Click to see 313.30 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
> Lignans, neolignans and related compounds / Furanoid lignans
(3R,3aS,6S,6aS)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan 51407985 Click to see COC1=CC(=CC(=C1OC)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC)OC 446.50 unknown https://doi.org/10.1080/14786410802394132
1,4-Bis(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan 99091 Click to see 446.50 unknown https://doi.org/10.1080/14786410802394132
Syringaresinol 100067 Click to see 418.40 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
Syringaresinol, (+)- 443023 Click to see 418.40 unknown https://doi.org/10.1007/S10600-008-0043-7
https://doi.org/10.1007/S10600-010-9708-0
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Palmitic Acid 985 Click to see 256.42 unknown https://doi.org/10.1007/S10600-008-0043-7
Stearic Acid 5281 Click to see 284.50 unknown https://doi.org/10.1007/S10600-008-0043-7
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
9,12-Octadecadienoic Acid 3931 Click to see 280.40 unknown https://doi.org/10.1007/S10600-008-0043-7
Linoleic Acid 5280450 Click to see 280.40 unknown https://doi.org/10.1007/S10600-008-0043-7
> Lipids and lipid-like molecules / Prenol lipids / Polyprenols / Bactoprenols
(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-ol 10836209 Click to see 426.70 unknown https://doi.org/10.1007/S10600-010-9708-0
CID 13559233 13559233 Click to see CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C 426.70 unknown https://doi.org/10.1080/14786410802394132
Farnesylfarnesol 54290761 Click to see CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C 426.70 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1080/14786410802394132
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
(+)-4,11-Eudesmadien-3-one 273568 Click to see CC1=C2CC(CCC2(CCC1=O)C)C(=C)C 218.33 unknown https://doi.org/10.1080/14786410802394132
(+)-alpha-Cyperone 6452086 Click to see 218.33 unknown https://doi.org/10.1080/14786410802394132
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
Epoxyparthenolide 154933 Click to see CC12CCC3C(C4C(O4)(CCC1O2)C)OC(=O)C3=C 264.32 unknown https://doi.org/10.1007/S10600-008-0043-7
Michelenolide 442278 Click to see 264.32 unknown https://doi.org/10.1007/S10600-008-0043-7
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Sesquiterpene lactones / Germacranolides and derivatives
[(1S,2R,4R,7E,10S,11R)-4,8-dimethyl-12-methylidene-13-oxo-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-10-yl] acetate 162995690 Click to see CC1=CCCC2(C(O2)C3C(C(C1)OC(=O)C)C(=C)C(=O)O3)C 306.40 unknown https://doi.org/10.1007/S10600-008-0043-7
CID 317831 317831 Click to see CC1=CCCC2(C(O2)C3C(C(C1)OC(=O)C)C(=C)C(=O)O3)C 306.40 unknown https://doi.org/10.1007/S10600-008-0043-7
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown https://doi.org/10.1007/S10600-008-0043-7
https://doi.org/10.1007/S10600-010-9708-0
17-(5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 122544 Click to see 412.70 unknown https://doi.org/10.1007/S10600-008-0043-7
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1007/S10600-008-0043-7
https://doi.org/10.1007/S10600-010-9708-0
Fucostanol 6743 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C)C(C)C 416.70 unknown https://doi.org/10.1007/S10600-010-9708-0
Sitostanol 241572 Click to see 416.70 unknown https://doi.org/10.1007/S10600-010-9708-0
Stigmasterol 5280794 Click to see 412.70 unknown https://doi.org/10.1007/S10600-008-0043-7
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Benzaldehydes / Hydroxybenzaldehydes
4-Hydroxybenzaldehyde 126 Click to see 122.12 unknown https://doi.org/10.1007/S10600-010-9708-0
https://doi.org/10.1007/S10600-008-0043-7
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives
N-feruloyltyramine; Moupinamide 125213 Click to see 313.30 unknown https://doi.org/10.1007/S10600-008-0043-7
https://doi.org/10.1007/S10600-010-9708-0

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