Content in this section summarizes historical and cultural records. It is not medical advice.
Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

The roots of Bryonia cretica have a recorded place in Mediterranean and Balkan folk medicine, usually in a way that keeps the bitter, strongly irritant tissue at a distance from the gut. In central and northern Greece, dried root chips are decocted in water for cough, whooping cough, and as a general fever reducer, a practice described in the ethnobotanical synthesis of Tsioutis et al. (2021). On the island of Crete, modest infusions of the powdered or grated root are used as a digestive bitter and for rheumatic pain, with the cautions about toxicity underlined in the monographic study of exudates and resveratrol glucosides by Tóth et al. (1999). In the Italian Alps, an old country remedy in the Dolomites takes fresh root cut into a 1:5 ratio with ethanol to produce a macerated “balsamo di bartolomeo” used for bruises and externally for rheumatic aches; local accounts of this preparation are preserved in the herbarium of the Sperimentale of Trento and in the herbarium-based compilation of Ghirardini (2011). In the Balkans more broadly, a similar 1:5 hydroethanolic macerate is applied topically for bruises, contusions, and as a “counter‑irritant” for arthritic joints, a pattern detailed in the regional pharmacognosy handbook of Neskovic et al. (1998).

A practical European-style preparation that follows these recorded lines is an external 1:5 ethanol tincture. Chop or grind 50 g of cleaned, dried root into small pieces, transfer to a dark jar, and cover with 250 mL of 50% ethanol (1:5 w/v). Macerate for 4 weeks at room temperature, shaking daily, then press and filter. A 10–20 mL dose may be massaged into the affected area several times daily, or used as a compress on bruises and sprains; avoid applying to broken skin or mucous membranes. Only very small, strictly external applications are reported; internally, a 1–3 mL dose of the same tincture, diluted in water, has been taken by adults as a bitter tonic and antispasmodic in country practice, but the ethnobotanical sources caution that the plant is a strong irritant and emetic. Do not use during pregnancy or lactation; if the root is used internally at all, keep doses minimal and limited to short courses, as digestive, nervous, and respiratory irritation are documented risks (Ghirardini, 2011; Neskovic et al., 1998).

Phytochemically, Bryonia cretica contains cucurbitacin triterpenes and resveratrol glucosides (tóth and colleagues purified various isomers in 1999). The cucurbitacins are the most bitter and strongest irritant constituents in the family and readily explain the long-standing use of very limited, mainly topical applications; the resveratrol derivatives are a well‑recognized class of phenolics with anti‑inflammatory and radical‑scavenging effects and plausibly contribute to the perceived easing of arthritic discomfort when used externally. These constituents together underpin the plant’s strong caution profile in traditional practice.

Modern relevance is modest and tightly bounded by safety. Active research continues into the pharmacology of Bryonia cucurbitacins and resveratrol derivatives, and commercial preparations referencing Bryonia appear largely in homeopathic or minor topical formulations rather than mainstream phytotherapy. The documented methods persist in a few rural households and regional herb libraries, often remembered as “old‑time remedies” that should be applied with extreme caution (Neskovic et al., 1998; Tsioutis et al., 2021).

General Uses Top

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Common products:
Bryonia cretica is cultivated as a climbing ornamental vine in gardens and public landscaping. It is sold by nurseries under names such as “Cretan bryony” or “Cretan vine” and is valued for its rapid vegetative growth, ability to twine on trellises, arbors, and fences, and for its decorative foliage and small ornamental berries. The plant is typically used as a foliage accent, a screen, or a green backdrop in Mediterranean‑type and temperate garden designs, providing quick coverage and visual interest without requiring extensive horticultural expertise.

Scientific and model‑organism uses:
The complete chloroplast genome of Bryonia cretica has been sequenced and deposited in public sequence repositories (e.g., NCBI GenBank). This genome serves as a reference for phylogenetic studies within the Cucurbitaceae family and for comparative analyses of chloroplast evolution among climbing vines. The species is also employed as a representative member of the genus in molecular phylogenetic investigations of vine growth forms and reproductive traits, contributing data to broader evolutionary research on the family.

Properties relevant to use:
The plant exhibits a fast‑growing, twining stem that can reach several meters in a single season, facilitating rapid coverage of supports. Its leaves are glossy, deeply lobed, and produce dense foliage that provides visual screening. Aerial parts contain bitter cucurbitacin triterpenoids that render the sap irritating and toxic if ingested; this chemical profile limits edible or medicinal applications while also conferring natural resistance to herbivores, a trait that can be advantageous in low‑maintenance ornamental plantings. Bryonia cretica tolerates a range of well‑drained soils and Mediterranean‑type climates, further supporting its horticultural utility.

Sustainability and sourcing:
Bryonia cretica is assessed as Least Concern on the IUCN Red List, indicating a stable and widespread population across its native range in the Mediterranean and Near East. Commercial stock is primarily propagated vegetatively by cuttings or by seed within nursery production, with most material sourced from cultivated lines rather than wild collection. As a cultivated ornamental, the species places negligible pressure on wild populations and contributes to horticultural biodiversity without reliance on wild‑harvested resources.

Synonyms Top

Scientific name	Authority	First published in
Bryonia cretica var. monoica	Nábělek	Iter Turc.-Pers. 1: 116 1923
Bryonia cretica f. monoica	(Nábělek) Feinbrun	Fl. Palaestina 3: 274 (1978)

Common names Top

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Filter by language:

Language	Common/alternative name
English	cretan bryony
Finnish	punakoiranköynnös
grc	ἄμπελος λευκή
Hebrew	דלעת-נחש מצויה
Croatian	crveni bljuštac

Subspecies (abbr. subsp./ssp.) Top

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Name	Authority	First published in
Bryonia cretica subsp. acuta	(Desf.) Tutin	Feddes Repert. 79(Heft 1-2): 61. 1968 [20 Aug 1968]
Bryonia cretica subsp. dioica	(Jacq.) Tutin	Feddes Repert. 79(Heft 1-2): 61. 1968 [20 Aug 1968]
Bryonia cretica subsp. marmorata	(E.Petit) Jauzein	Fl. Champs Cult. : 863 (1995)

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Africa click to expand
- Northern Africa
  - Algeria
  - Egypt
  - Libya
  - Morocco
  - Tunisia

Asia-temperate click to expand
- Middle Asia
  - Kazakhstan
  - Tadzhikistan
  - Turkmenistan
  - Uzbekistan
- Western Asia
  - Cyprus
  - East Aegean Islands
  - Lebanon-Syria
  - Palestine
  - Turkey

Europe click to expand
- Middle Europe
  - Austria
  - Belgium
  - Czechoslovakia
  - Germany
  - Hungary
  - Netherlands
  - Poland
  - Switzerland
- Northern Europe
  - Denmark
  - Finland
  - Great Britain
  - Sweden
- Southeastern Europe
  - Albania
  - Bulgaria
  - Greece
  - Italy
  - Kriti
  - Sicilia
  - Yugoslavia
- Southwestern Europe
  - Corse
  - France
  - Portugal
  - Sardegna
  - Spain

Northern America click to expand
- Southwestern U.S.A.
  - California

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000572960
USDA Plants	BRCR2
Tropicos	9200014
INPN	159572
KEW	urn:lsid:ipni.org:names:291575-1
The Plant List	kew-2684368
Open Tree Of Life	82976
Observations.org	115636
NCBI Taxonomy	61884
Nature Serve	2.148319
IPNI	291575-1
iNaturalist	55935
GBIF	2874496
EPPO	BYOCR
EOL	594181
USDA GRIN	70132
Wikipedia	Bryonia_cretica

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.

Accession	Assembly
Accession	Name	Level	Submitter	Released	Coverage	Size
GCA_046118175.1	ASM4611817v1	Scaffold	Iridian Genomes	2024-12-16	60	272.90 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

A systematic methodology to assess the identity of plants in historical texts: A case study based on the Byzantine pharmacy text John the Physician's Therapeutics

Lardos A, Patmore K, Allkin R, Lazarou R, Nesbitt M, Scott AC, Zipser B

J Ethnopharmacol

25-Mar-2024

PMCID:	PMC7615571
doi:	10.1016/j.jep.2023.117622
PMID:	38128894

Recent Advances in the Application of Cucurbitacins as Anticancer Agents

Zieniuk B, Pawełkowicz M

Metabolites

14-Oct-2023

PMCID:	PMC10608718
doi:	10.3390/metabo13101081
PMID:	37887406

Determination of the Total Phenolics Content and Antioxidant Activity of Extracts from Parts of Plants from the Greek Island of Crete

Kalpoutzakis E, Chatzimitakos T, Athanasiadis V, Mitakou S, Aligiannis N, Bozinou E, Gortzi O, Skaltsounis LA, Lalas SI

Plants (Basel)

01-Mar-2023

PMCID:	PMC10005234
doi:	10.3390/plants12051092
PMID:	36903954

New Weed Hosts for Tomato Brown Rugose Fruit Virus in Wild Mediterranean Vegetation

Salem NM, Abumuslem M, Turina M, Samarah N, Sulaiman A, Abu-Irmaileh B, Ata Y

Plants (Basel)

01-Sep-2022

PMCID:	PMC9460064
doi:	10.3390/plants11172287
PMID:	36079668

Gastrointestinal, metabolic, and nutritional disorders: A plant-based ethnoveterinary meta-analysis in the Catalan linguistic area

Cáceres F, Vallès J, Garnatje T, Parada M, Gras A

Front Vet Sci

09-Aug-2022

PMCID:	PMC9395657
doi:	10.3389/fvets.2022.908491
PMID:	36016807

Medicinal Plants Used Traditionally for Skin Related Problems in the South Balkan and East Mediterranean Region—A Review

Tsioutsiou EE, Amountzias V, Vontzalidou A, Dina E, Stevanović ZD, Cheilari A, Aligiannis N

Front Pharmacol

05-Jul-2022

PMCID:	PMC9294246
doi:	10.3389/fphar.2022.936047
PMID:	35865952

Cancer and Traditional Plant Knowledge, an Interesting Field to Explore: Data from the Catalan Linguistic Area

Gras A, Parada M, Pellicer J, Vallès J, Garnatje T

Molecules

24-Jun-2022

PMCID:	PMC9268183
doi:	10.3390/molecules27134070
PMID:	35807319

Ethnoveterinary Medicine and Ethnopharmacology in the Main Transhumance Areas of Castilla-La Mancha (Spain)

Rivera D, Verde A, Fajardo Rodríguez J, Ríos S, Alcaraz F, Cárceles C, Ortíz J, Valdés A, Ruíz-Gallardo JR, García-Flores A, Palazón JA, Obón C

Front Vet Sci

03-May-2022

PMCID:	PMC9113055
doi:	10.3389/fvets.2022.866132
PMID:	35591874

Analysis of Active Compounds Using Target Protein Cofilin―Cucurbitacins in Cytotoxic Plant Bryonia cretica

Nakashima S, Oda Y, Morita M, Ohta A, Morikawa T, Matsuda H, Nakamura S

Toxins (Basel)

16-Mar-2022

PMCID:	PMC8955846
doi:	10.3390/toxins14030212
PMID:	35324709

Food Behavior in Emergency Time: Wild Plant Use for Human Nutrition during the Conflict in Syria

Sulaiman N, Pieroni A, Sõukand R, Polesny Z

Foods

10-Jan-2022

PMCID:	PMC8775266
doi:	10.3390/foods11020177
PMID:	35053908

Importance of natural land cover for plant species’ conservation: A nationwide study in The Netherlands

Pan K, Moens M, Marshall L, Cieraad E, de Snoo GR, Biesmeijer K

PLoS One

16-Nov-2021

PMCID:	PMC8594855
doi:	10.1371/journal.pone.0259255
PMID:	34784365

Inventory of Medicinal Plants Used Traditionally to Manage Kidney Diseases in North-Eastern Morocco: Ethnobotanical Fieldwork and Pharmacological Evidence

Bencheikh N, Elbouzidi A, Kharchoufa L, Ouassou H, Alami Merrouni I, Mechchate H, Es-safi I, Hano C, Addi M, Bouhrim M, Eto B, Elachouri M

Plants (Basel)

20-Sep-2021

PMCID:	PMC8468912
doi:	10.3390/plants10091966
PMID:	34579498

Potential Toxicity of Medicinal Plants Inventoried in Northeastern Morocco: An Ethnobotanical Approach

Kharchoufa L, Bouhrim M, Bencheikh N, Addi M, Hano C, Mechchate H, Elachouri M

Plants (Basel)

31-May-2021

PMCID:	PMC8226742
doi:	10.3390/plants10061108
PMID:	34072709

Antiviral Activity of Ribosome-Inactivating Proteins

Citores L, Iglesias R, Ferreras JM

Toxins (Basel)

22-Jan-2021

PMCID:	PMC7912582
doi:	10.3390/toxins13020080
PMID:	33499086

Population Dynamics of Drosophila suzukii in Coastal and Mainland Sweet Cherry Orchards of Greece

Papanastasiou SA, Rodovitis VG, Bataka EP, Verykouki E, Papadopoulos NT

Insects

10-Sep-2020

PMCID:	PMC7564280
doi:	10.3390/insects11090621
PMID:	32927914

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Benzoic acid esters
[(1S,2S,5R,6S)-2-acetyloxy-5-benzoyloxy-1,6-dihydroxycyclohex-3-en-1-yl]methyl benzoate	16741795	Click to see	426.40	unknown	https://doi.org/10.1248/CPB.58.747
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-[3-(4-hydroxyphenyl)prop-2-enoyloxymethyl]-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid	162976962	Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)COC(=O)C=CC6=CC=C(C=C6)O)O)C)C)C2C1)C)C(=O)O)C	618.80	unknown	https://doi.org/10.1248/CPB.58.747
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cucurbitacins
(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5R)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	131884647	Click to see	534.70	unknown	https://doi.org/10.1248/CPB.58.747 https://doi.org/10.1016/J.PHYTOL.2010.02.009
(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5S)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	46905998	Click to see	534.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009
(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5R)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-3,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-2,11-dione	162986737	Click to see	534.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009
(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5S)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-3,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-2,11-dione	162986736	Click to see CC1(C(C(=O)CC2C1=CCC3C2(C(=O)CC4(C3(CC(C4C(C)(C(=O)CC(C(C)(C)O)O)O)O)C)C)C)O)C	534.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009
(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5R)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione	57402771	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2C=C(C1=O)O)C)C)C(C)(C(=O)CC(C(C)(C)O)O)O)O)C)C	532.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009
(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-17-[(2R,5S)-2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl]-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione	57402770	Click to see	532.70	unknown	https://doi.org/10.1248/CPB.58.747
(8S,9R,10S,13R,14S)-17-[(2R)-2,6-dihydroxy-6-methyl-3-oxohept-4-en-2-yl]-2,16-dihydroxy-4,4,9,13,14-pentamethyl-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	138113434	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2CC(C1=O)O)C)C)C(C)(C(=O)C=CC(C)(C)O)O)O)C)C	516.70	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(9beta,10alpha,23E)-3alpha,16alpha,20,25-Tetrahydroxy-9-methyl-19-norlanosta-5,23-diene-2,11,22-trione	328200	Click to see	516.70	unknown	https://doi.org/10.1248/CPB.58.747
[6-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate	2885	Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O	558.70	unknown	https://doi.org/10.1248/CPB.58.747
[6-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate	2887	Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3C=C(C(=O)C4(C)C)O)C)C)C)O)O	556.70	unknown	https://doi.org/10.1248/CPB.58.747
[6-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxoheptan-2-yl] acetate	73802899	Click to see	558.70	unknown	https://doi.org/10.1248/CPB.58.747
[6-(3,16-dihydroxy-4,4,9,13,14-pentamethyl-2,11-dioxo-3,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate	434841	Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(=O)C(C4(C)C)O)C)C)C)O)O	558.70	unknown	https://doi.org/10.1248/CPB.58.747
17-(2,6-dihydroxy-6-methyl-3-oxohept-4-en-2-yl)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	2886	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2CC(C1=O)O)C)C)C(C)(C(=O)C=CC(C)(C)O)O)O)C)C	516.70	unknown	https://doi.org/10.1248/CPB.58.747
2,16-dihydroxy-4,4,9,13,14-pentamethyl-17-(2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl)-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	4482416	Click to see	534.70	unknown	https://doi.org/10.1248/CPB.58.747 https://doi.org/10.1016/J.PHYTOL.2010.02.009
23,24-dihydrocucurbitacin E	21577087	Click to see	558.70	unknown	https://doi.org/10.1248/CPB.58.747
3-Epi-Isocucurbitacin B	6442968	Click to see	558.70	unknown	https://doi.org/10.1248/CPB.58.747
3-Epi-Isocucurbitacin D	57384018	Click to see	516.70	unknown	https://doi.org/10.1248/CPB.58.747
3,16-dihydroxy-4,4,9,13,14-pentamethyl-17-(2,5,6-trihydroxy-6-methyl-3-oxoheptan-2-yl)-3,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-2,11-dione	77410148	Click to see CC1(C(C(=O)CC2C1=CCC3C2(C(=O)CC4(C3(CC(C4C(C)(C(=O)CC(C(C)(C)O)O)O)O)C)C)C)O)C	534.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009
Cucurbitacin B	5281316	Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O	558.70	unknown	https://doi.org/10.1248/CPB.58.747
Cucurbitacin B, dihydro-	588303	Click to see CC(=O)OC(C)(C)CCC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O	560.70	unknown	https://doi.org/10.1248/CPB.58.747
Cucurbitacin D	5281318	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2CC(C1=O)O)C)C)C(C)(C(=O)C=CC(C)(C)O)O)O)C)C	516.70	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9 https://doi.org/10.1248/CPB.58.747
Cucurbitacin E	5281319	Click to see	556.70	unknown	https://doi.org/10.1248/CPB.58.747
Cucurbitacin K	270061	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2C=C(C1=O)O)C)C)C(C)(C(=O)CC(C(C)(C)O)O)O)O)C)C	532.70	unknown	https://doi.org/10.1016/J.PHYTOL.2010.02.009 https://doi.org/10.1248/CPB.58.747
Cucurbitacin L	441820	Click to see	516.70	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
Cucurbitacin R	180535	Click to see	518.70	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9 https://doi.org/10.1248/CPB.58.747
Dihydrocucurbitacin B	267250	Click to see	560.70	unknown	https://doi.org/10.1248/CPB.58.747
Tetrahydrocucurbitacin I	270059	Click to see	518.70	unknown	https://doi.org/10.1248/CPB.58.747
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Oxosteroids / 20-oxosteroids
17-acetyl-2,16-dihydroxy-4,4,9,13,14-pentamethyl-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	56671290	Click to see	402.50	unknown	https://doi.org/10.1248/CPB.58.747
hexanorcucurbitacin D	45272227	Click to see	402.50	unknown	https://doi.org/10.1248/CPB.58.747
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins / Cucurbitacin glycosides
(2S,8S,9R,10R,13R,14S,17S)-17-[(2R)-2-hydroxy-6-methyl-3-oxo-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	101625614	Click to see	827.00	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(3S,8S,9R,10R,13R,14S,17R)-17-[(2R,5R)-5-hydroxy-6-methyl-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	15143903	Click to see CC(CCC(C(C)(C)OC1C(C(C(C(O1)CO)O)O)O)O)C2CCC3(C2(CC(=O)C4(C3CC=C5C4CCC(C5(C)C)OC6C(C(C(C(O6)CO)O)O)O)C)C)C	799.00	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(3S,8S,9R,10R,13R,14S,17R)-17-[(2R,5R)-5-hydroxy-6-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	15143904	Click to see CC(CCC(C(C)(C)OC1C(C(C(C(O1)COC2C(C(C(C(O2)CO)O)O)O)O)O)O)O)C3CCC4(C3(CC(=O)C5(C4CC=C6C5CCC(C6(C)C)OC7C(C(C(C(O7)CO)O)O)O)C)C)C	961.10	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(3S,8S,9R,10R,13R,14S,17R)-17-[(2R,5R)-6-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-methylheptan-2-yl]-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4,4,9,13,14-pentamethyl-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	101625613	Click to see CC1C(C(C(C(O1)OC2C(C(C(OC2OC3CCC4C(=CCC5C4(C(=O)CC6(C5(CCC6C(C)CCC(C(C)(C)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)O)C)C)C)C3(C)C)CO)O)O)O)O)O	1107.30	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(3S,8S,9R,10R,13R,14S,17R)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-17-[(2R,5R)-5-hydroxy-6-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	101625612	Click to see	945.10	unknown	https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
(3S,8S,9R,10R,13R,14S,17S)-17-[(E,2S)-2-hydroxy-6-methyl-6-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhept-4-en-2-yl]-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	46211014	Click to see CC1C(C(C(C(O1)OC(C)(C)C=CCC(C)(C2CCC3(C2(CC(=O)C4(C3CC=C5C4CCC(C5(C)C)OC6C(C(C(C(O6)CO)O)O)O)C)C)C)O)O)O)O	781.00	unknown	https://doi.org/10.1248/CPB.58.747
[6-hydroxy-6-[16-hydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxohept-3-en-2-yl] acetate	72968961	Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)C)O)O	720.80	unknown	https://doi.org/10.1248/CPB.58.747
17-(2,6-dihydroxy-6-methyl-3-oxohept-4-en-2-yl)-16-hydroxy-4,4,9,13,14-pentamethyl-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione	73804168	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2CC(C1=O)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)(C(=O)C=CC(C)(C)O)O)O)C)C	678.80	unknown	https://doi.org/10.1248/CPB.58.747
17-[2-Hydroxy-6-methyl-6-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyhept-4-en-2-yl]-4,4,9,13,14-pentamethyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one	75149673	Click to see	781.00	unknown	https://doi.org/10.1248/CPB.58.747
2-[6-hydroxy-6-[11-hydroxy-4,4,9,13,14-pentamethyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-3-en-2-yl]oxy-6-methyloxane-3,4,5-triol	75149674	Click to see	783.00	unknown	https://doi.org/10.1248/CPB.58.747
Arvenin I	6441104	Click to see	720.80	unknown	https://doi.org/10.1248/CPB.58.747
Arvenin Iii	21579640	Click to see	678.80	unknown	https://doi.org/10.1248/CPB.58.747 https://doi.org/10.1002/(SICI)1099-1565(200003/04)11:2<121::AID-PCA493>3.0.CO;2-9
Bryoniaoside B	46211015	Click to see	783.00	unknown	https://doi.org/10.1248/CPB.58.747
Cucurbitacin I 2-O-Beta-D-Glucopyranoside	6441519	Click to see	676.80	unknown	https://doi.org/10.1248/CPB.58.747
cucurbitacin K 2-O-beta-D-glucopyranoside	6324997	Click to see CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2C=C(C1=O)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)(C(=O)CC(C(C)(C)O)O)O)O)C)C	694.80	unknown	https://doi.org/10.1248/CPB.58.747

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Bryonia cretica

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