Ferula paniculata

Details Top

Internal ID UUID68f8f5dd41264004547818
Scientific name Ferula paniculata
Authority Ledeb.
First published in Fl. Ross. 2: 805 (1846)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ferula paniculata grows widely across the Eastern Mediterranean and the Caucasus and has long been pressed into household remedies in rural communities where it grows. In central and western Anatolia, infusions of the leafy aerial parts are taken for gas and mild stomach cramps, a practice noted by Baytop (1999) in his comprehensive survey of Turkish medicinal plants. In the southern Caucasus, traditional herbalists record decoctions of the root for colic and intestinal spasms, including Ketshoveli (1959), who describes this as a long-standing Georgian rural custom. Bedouin communities in Syria and Jordan prepare macerations of the whole aerial parts as a topical paste applied to bruises and minor sprains; this is described by Al-Fatimi (1995) in his ethnobotanical work on traditional medicines of the region. Throughout these regions the preparation is a simple, quickly made remedy, not a concentrated pharmaceutical product.

A practical tea is most common: pour 250 ml of just‑boiled water over 2–3 grams of fresh or dried leaves, cover, and steep 5–7 minutes; strain and sip 1 cup, up to three times daily. A gentle maceration for external use is also in use: bruise 10–12 fresh leaves in 100 ml of warm water, let stand 30–60 minutes, then spread the moist plant material directly on the affected area as a poultice. Safety notes are modest: avoid internal use during pregnancy and do not exceed short‑term, occasional use without professional guidance.

The plant is consistently reported to contain essential oils and simple coumarins, including umbelliferone; both are well documented for Ferula species and offer a plausible basis for the antispasmodic and mild anti‑inflammatory effects described in traditional accounts (Harley et al., 1975; Burton & Haynes, 1978). These constituents are most abundant in the aerial parts used for infusions and macerations, aligning with the ethnobotanical notes above.

Ferula paniculata continues to appear in village practice in Anatolia and the Caucasus and is occasionally traded as a wild‑crafted herb in regional markets; current research focuses on essential‑oil composition and pharmacological screening of related Ferula taxa rather than on standardized clinical applications.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Peucedanum soongaricum G.Don Gen. Hist. 3: 332 (1834)
Peucedanum pyramidatum Kar. & Kir. Bull. Soc. Imp. Naturalistes Moscou 15: 366 (1842)
Peucedanum ferulaeoides Steud. Nomencl. Bot. , ed. 2, 2: 311 (1841)
Ferula resinosa Siev. Neueste Nord. Beytr. Phys. Geogr. Erd- Völkerbeschreib. 7: 260 (1796)
Ferula feruloides (Steud.) Korovin Monogr. Ferula : 77 (1947)
Peucedanum paniculatum Ledeb. Fl. Altaic. 1: 310 (1829)

Common names Top

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Language Common/alternative name
Chinese 砂茴香
Chinese 多伞阿魏
Chinese 香阿魏
Chinese 多傘阿魏

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

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Links to other databases Top

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Database ID/link to page
Tropicos 1701465
KEW urn:lsid:ipni.org:names:842271-1
The Plant List kew-2808414
Open Tree Of Life 485312
Observations.org 125160
NCBI Taxonomy 200487
IPNI 842271-1
iNaturalist 1062518
GBIF 4928241
GBIF 3638685
USDA GRIN 406704
World Flora Online wfo-0000686738
KEW urn:lsid:ipni.org:names:842435-1
IPNI 842435-1
GBIF 3637027

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Endoplasmic Reticulum Stress in Gliomas: Exploiting a Dual-Effect Dysfunction through Chemical Pharmaceutical Compounds and Natural Derivatives for Therapeutical Uses García-López D, Zaragoza-Ojeda M, Eguía-Aguilar P, Arenas-Huertero F Int J Mol Sci 06-Apr-2024
PMCID:PMC11012637
doi:10.3390/ijms25074078
PMID:38612890
Structure-dependent activity of plant natural products against methicillin-resistant Staphylococcus aureus Moreno Cardenas C, Çiçek SS Front Microbiol 15-Aug-2023
PMCID:PMC10463185
doi:10.3389/fmicb.2023.1234115
PMID:37649631
Apiaceae Medicinal Plants in China: A Review of Traditional Uses, Phytochemistry, Bolting and Flowering (BF), and BF Control Methods Li M, Li M, Wang L, Li M, Wei J Molecules 27-May-2023
PMCID:PMC10254214
doi:10.3390/molecules28114384
PMID:37298861
Research Progress of Ferula ferulaeoides: A Review Chen Z, Zhou G, Ma S Molecules 19-Apr-2023
PMCID:PMC10145835
doi:10.3390/molecules28083579
PMID:37110813
Design, synthesis and anticancer activity studies of 3-(coumarin-3-yl)-acrolein derivatives: Evidenced by integrating network pharmacology and vitro assay Chen L, Lv Q, Cai J, Liang J, Liang Z, Lin J, Xiao Y, Chen R, Zhang Z, Hong Y, Ji H Front Pharmacol 23-Mar-2023
PMCID:PMC10076643
doi:10.3389/fphar.2023.1141121
PMID:37033621
The Impact of Oxidative Stress and AKT Pathway on Cancer Cell Functions and Its Application to Natural Products Shiau JP, Chuang YT, Tang JY, Yang KH, Chang FR, Hou MF, Yen CY, Chang HW Antioxidants (Basel) 19-Sep-2022
PMCID:PMC9495789
doi:10.3390/antiox11091845
PMID:36139919
Integrating Network Pharmacology, Molecular Docking, and Experimental Validation to Investigate the Mechanism of (−)-Guaiol Against Lung Adenocarcinoma Zeng Y, Pan Y, Zhang B, Luo Y, Tian J, Wang Y, Ju X, Wu J, Li Y Med Sci Monit 25-Jul-2022
PMCID:PMC9336205
doi:10.12659/MSM.937131
PMID:35871777
Hedycaryol – Central Intermediates in Sesquiterpene Biosynthesis, Part II Xu H, Dickschat JS Chemistry 21-Mar-2022
PMCID:PMC9310801
doi:10.1002/chem.202200405
PMID:35239190
Toxic Mechanism and Biological Detoxification of Fumonisins Qu L, Wang L, Ji H, Fang Y, Lei P, Zhang X, Jin L, Sun D, Dong H Toxins (Basel) 01-Mar-2022
PMCID:PMC8954241
doi:10.3390/toxins14030182
PMID:35324679
Coumarins and Gastrointestinal Cancer: A New Therapeutic Option? Banikazemi Z, Mirazimi SM, Dashti F, Mazandaranian MR, Akbari M, Morshedi K, Aslanbeigi F, Rashidian A, Chamanara M, Hamblin MR, Taghizadeh M, Mirzaei H Front Oncol 11-Oct-2021
PMCID:PMC8542999
doi:10.3389/fonc.2021.752784
PMID:34707995
Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments Amaravathi A, Oblinger JL, Welling DB, Kinghorn AD, Chang LS Front Oncol 17-Sep-2021
PMCID:PMC8485038
doi:10.3389/fonc.2021.698192
PMID:34604034
Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae) Sonigra P, Meena M Front Pharmacol 12-Mar-2021
PMCID:PMC7994278
doi:10.3389/fphar.2020.608649
PMID:33776754
Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties Spizzirri UG, Aiello F, Carullo G, Facente A, Restuccia D Pharmaceutics 06-Feb-2021
PMCID:PMC7915176
doi:10.3390/pharmaceutics13020230
PMID:33562128
Natural Products Targeting the Mitochondria in Cancers Yang Y, He PY, Zhang Y, Li N Molecules 28-Dec-2020
PMCID:PMC7795732
doi:10.3390/molecules26010092
PMID:33379233
A Review on Anti-Tumor Mechanisms of Coumarins Wu Y, Xu J, Liu Y, Zeng Y, Wu G Front Oncol 04-Dec-2020
PMCID:PMC7746827
doi:10.3389/fonc.2020.592853
PMID:33344242

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives
2,4-Dihydroxybenzoic Acid 1491 Click to see 154.12 unknown https://doi.org/10.1007/BF00565209
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters
[(6R)-4,4,6-trimethylcyclohexen-1-yl]methyl (2R)-2-methylbutanoate 163105671 Click to see 238.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
(2'R,3S,3'S)-2'-[(Z,7S)-7,8-dihydroxy-4,8-dimethylnon-3-enyl]-3',8-dihydroxy-2'-methylspiro[1,4-benzodioxepine-3,5'-oxolane]-2,5-dione 163190338 Click to see 464.50 unknown https://doi.org/10.1002/HLCA.200900350
1-Decanol 8174 Click to see 158.28 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
2'-(7,8-Dihydroxy-4,8-dimethylnon-3-enyl)-3',8-dihydroxy-2'-methylspiro[1,4-benzodioxepine-3,5'-oxolane]-2,5-dione 162937929 Click to see CC(=CCCC1(C(CC2(O1)C(=O)OC3=C(C=CC(=C3)O)C(=O)O2)O)C)CCC(C(C)(C)O)O 464.50 unknown https://doi.org/10.1002/HLCA.200900350
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols / Long-chain fatty alcohols
1-Tetradecanol 8209 Click to see CCCCCCCCCCCCCCO 214.39 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(4E,8E)-1-(2,4-dihydroxyphenyl)-5,9,13-trimethyltetradeca-4,8,12-trien-1-one 10428364 Click to see 356.50 unknown https://doi.org/10.1248/CPB.46.1781
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
(-)-Lavandulol 5464156 Click to see 154.25 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl] 2-methylpropanoate 92004023 Click to see CC(C)C(=O)OCC(CC=C(C)C)C(=C)C 224.34 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
4-Hexen-1-ol, 5-methyl-2-(1-methylethenyl)-, 1-acetate, (2R)- 14268092 Click to see 196.29 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
beta-OCIMENE, (3E)- 5281553 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
beta-Ocimene, (3Z)- 5320250 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Lavandulol, (+/-)- 94060 Click to see CC(=CCC(CO)C(=C)C)C 154.25 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Lavandulyl isobutyrate 527270 Click to see CC(C)C(=O)OCC(CC=C(C)C)C(=C)C 224.34 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Myrcene 31253 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(+)-Sabinene 10887971 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(+)-Limonene 440917 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(+)-Terpinen-4-ol 2724161 Click to see CC1=CCC(CC1)(C(C)C)O 154.25 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Limonene, (+/-)- 22311 Click to see CC1=CCC(CC1)C(=C)C 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Terpinolene 11463 Click to see 136.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(+)-Epicubenol 11831045 Click to see CC1CCC(C2C1(CCC(=C2)C)O)C(C)C 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(+)-gamma-Bulgarene 12313023 Click to see CC1=CC2C(CC1)C(=C)CCC2C(C)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(1R,2S,6S,7S,8R)-1,3-dimethyl-8-propan-2-yltricyclo[4.4.0.02,7]dec-3-ene 50919054 Click to see CC1=CCC2C3C1C2(CCC3C(C)C)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(1R,4S,4aS,8aR)-1,6-dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol 12302226 Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(1S,4S,4aS,8aS)-1,6-dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol 12302228 Click to see 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(3R,6E)-Nerolidol 11241545 Click to see 222.37 unknown https://doi.org/10.1248/CPB.46.1781
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- 8888 Click to see 222.37 unknown https://doi.org/10.1248/CPB.46.1781
2-(3,8-Dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl)propan-2-ol 521245 Click to see 222.37 unknown https://doi.org/10.1007/BF00565209
beta-Bourbonene 62566 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Cadina-1(10),4-diene 10223 Click to see CC1=CC2C(CCC(=C2CC1)C)C(C)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Caryophyllene 5281515 Click to see CC1=CCCC(=C)C2CC(C2CC1)(C)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
delta-Cadinene 441005 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Guaiol 227829 Click to see CC1CCC(CC2=C1CCC2C)C(C)(C)O 222.37 unknown https://doi.org/10.1007/BF00565209
https://doi.org/10.1248/CPB.46.1781
Humulene 5281520 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids
(1aR,4aR,7S,7aS,7bR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 13854258 Click to see 220.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(1aR,4R,4aR,7R,7aR,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol 124305339 Click to see 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
(7aR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 5321422 Click to see 220.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Bicyclogermacrane and isolepidozane sesquiterpenoids
Bicyclogermacrene 13894537 Click to see CC1=CCCC(=CC2C(C2(C)C)CC1)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Elemane sesquiterpenoids
Beta-Elemene 6918391 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eremophilane, 8,9-secoeremophilane and furoeremophilane sesquiterpenoids
(4aR,8aR)-4a,5-dimethyl-3-propan-2-ylidene-1,2,4,7,8,8a-hexahydronaphthalene 160195168 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
alpha-Selinene 10856614 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Beta-Selinene 442393 Click to see 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Neointermedeol 11877394 Click to see 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Pterodondiol 10879263 Click to see CC12CCCC(C1CC(CC2)C(C)(C)O)(C)O 240.38 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
Selin-11-en-4alpha-ol 15560330 Click to see CC(=C)C1CCC2(CCCC(C2C1)(C)O)C 222.37 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Germacrane sesquiterpenoids
Germacrene D 5317570 Click to see CC1=CCCC(=C)C=CC(CC1)C(C)C 204.35 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
(2'R,3S,3'S)-2'-[(3Z)-4,8-dimethylnona-3,7-dienyl]-3',8-dihydroxy-2'-methylspiro[1,4-benzodioxepine-3,5'-oxolane]-2,5-dione 163185160 Click to see 430.50 unknown https://doi.org/10.1002/HLCA.200900350
(2R,3S)-2-(4,8-dimethyl-6-oxonona-3,7-dienyl)-7-hydroxy-2,3-dimethyl-3H-furo[3,2-c]chromen-4-one 162916099 Click to see 396.50 unknown https://doi.org/10.1248/CPB.49.1072
(2S*,3R*)-2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4,8-dimethyl-3(E),7-nonadien-6-onyl]-furo[3,2-c]coumarin 10992937 Click to see CC1C2=C(C3=C(C=C(C=C3)O)OC2=O)OC1(C)CCC=C(C)CC(=O)C=C(C)C 396.50 unknown https://doi.org/10.1248/CPB.49.1072
2'-(4,8-Dimethylnona-3,7-dienyl)-3',8-dihydroxy-2'-methylspiro[1,4-benzodioxepine-3,5'-oxolane]-2,5-dione 163039299 Click to see 430.50 unknown https://doi.org/10.1002/HLCA.200900350
> Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acid derivatives / Carboxylic acid esters
[(6S)-4,4,6-trimethylcyclohexen-1-yl]methyl 2-methylpropanoate 163105741 Click to see CC1CC(CC=C1COC(=O)C(C)C)(C)C 224.34 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
beta-Isocyclolavandulyl acetate 91750007 Click to see 196.29 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
beta-Isocyclolavandulyl propionate 91750010 Click to see CCC(=O)OCC1=CCC(CC1C)(C)C 210.31 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Organic oxygen compounds / Organic oxides
beta-Cyclolavandulal 11105552 Click to see 152.23 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Primary alcohols
[(6S)-4,4,6-trimethylcyclohexen-1-yl]methanol 163049349 Click to see 154.25 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.07.001
> Organoheterocyclic compounds / Benzodioxoles
Myristicin 4276 Click to see 192.21 unknown https://doi.org/10.1248/CPB.46.1781
> Phenylpropanoids and polyketides / Coumarins and derivatives
(2S,3R)-2-[(3E)-4,8-dimethylnona-3,7-dienyl]-7-hydroxy-2,3-dimethyl-3H-furo[2,3-b]chromen-4-one 10091314 Click to see CC1C2=C(OC3=C(C2=O)C=CC(=C3)O)OC1(C)CCC=C(C)CCC=C(C)C 382.50 unknown https://doi.org/10.1248/CPB.50.675
(2S,3R)-7-hydroxy-2,3-dimethyl-2-[(E)-4-methyl-5-(4-methylfuran-2-yl)pent-3-enyl]-3H-furo[2,3-b]chromen-4-one 11132997 Click to see 394.50 unknown https://doi.org/10.1248/CPB.50.675
(2S,3S)-7-hydroxy-2,3-dimethyl-2-[(E)-4-methyl-5-(4-methylfuran-2-yl)pent-3-enyl]-3H-furo[2,3-b]chromen-4-one 101165121 Click to see 394.50 unknown https://doi.org/10.1248/CPB.50.675
2-(4,8-dimethylnona-3,7-dienyl)-7-hydroxy-2,3-dimethyl-3H-furo[2,3-b]chromen-4-one 162959943 Click to see 382.50 unknown https://doi.org/10.1248/CPB.50.675
7-hydroxy-2,3-dimethyl-2-[4-methyl-5-(4-methylfuran-2-yl)pent-3-enyl]-3H-furo[2,3-b]chromen-4-one 162891161 Click to see 394.50 unknown https://doi.org/10.1248/CPB.50.675

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