Mosloflavone

Details

• Internal ID: c5e9fbb8-fd10-4529-8b9f-d732dc8a9bec
• Taxonomy: Phenylpropanoids and polyketides > Flavonoids > O-methylated flavonoids > 7-O-methylated flavonoids
• IUPAC Name: 5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one
• SMILES (Canonical): COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
• SMILES (Isomeric): COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
• InChI: InChI=1S/C17H14O5/c1-20-14-9-13-15(16(19)17(14)21-2)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3
• InChI Key: SIVAITYPYQQYAP-UHFFFAOYSA-N
• Popularity: 28 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₇H₁₄O₅
• Molecular Weight: 298.29 g/mol
• Exact Mass: 298.08412354 g/mol
• Topological Polar Surface Area (TPSA): 65.00 Ų
• XlogP: 3.30

Synonyms

• 740-33-0
• 5-Hydroxy-6,7-dimethoxyflavone
• 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one
• 5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one
• 5-HYDROXY-6,7-DIMETHOXYLFLAVONE
• 4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-phenyl-
• UNII-F4DL1FN60Q
• F4DL1FN60Q
• CHEMBL52676
• SCHEMBL971985
• 6,7-DIMETHOXYBAICALEIN
• MEGxp0_001406
• ACon1_000627
• DTXSID00224789
• 6,7-DI-O-METHYLBAICALEIN
• CHEBI:157727
• SIVAITYPYQQYAP-UHFFFAOYSA-N
• HY-N2036
• LMPK12111099
• BAICALEIN-6,7-DIMETHYL ETHER
• AKOS016013392
• NCGC00168899-01
• AC-34609
• MS-24281
• FLAVONE, 5-HYDROXY-6,7-DIMETHOXY-
• CS-0018526
• FT-0698911
• F17701
• 5-Hydroxy-6,7-dimethoxy-2-phenyl-chromen-4-one
• BRD-K65492022-001-01-8
• Q27277625
• 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one #

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	98.83%	91.11%
CHEMBL4261	Q16665	Hypoxia-inducible factor 1 alpha	97.31%	85.14%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	94.64%	95.56%
CHEMBL1293249	Q13887	Kruppel-like factor 5	94.53%	86.33%
CHEMBL2581	P07339	Cathepsin D	94.11%	98.95%
CHEMBL2635	P51452	Dual specificity protein phosphatase 3	93.84%	94.00%
CHEMBL1806	P11388	DNA topoisomerase II alpha	90.92%	89.00%
CHEMBL3091268	Q92753	Nuclear receptor ROR-beta	87.76%	95.50%
CHEMBL3038477	P67870	Casein kinase II alpha/beta	84.15%	99.23%
CHEMBL3060	Q9Y345	Glycine transporter 2	84.07%	99.17%
CHEMBL1860	P10827	Thyroid hormone receptor alpha	82.96%	99.15%
CHEMBL3192	Q9BY41	Histone deacetylase 8	82.12%	93.99%
CHEMBL4306	P22460	Voltage-gated potassium channel subunit Kv1.5	81.10%	94.03%
CHEMBL1255126	O15151	Protein Mdm4	80.14%	90.20%

Plants that contains it

• Andira surinamensis
• Aralia hispida
• Baeckea frutescens
• Balanophora polyandra
• Boeberastrum anthemidifolium
• Chenopodiastrum murale
• Chenopodium quinoa
• Citrus medica
• Collinsonia canadensis
• Coprosma foetidissima
• Cryptocarya chinensis
• Davidsonia pruriens
• Desmos dumosus
• Echinochloa crus-galli
• Elsholtzia ciliata
• Eriocephalus kingesii
• Euonymus alatus
• Geranium collinum
• Girgensohnia oppositiflora
• Harpullia cupanioides
• Isodon eriocalyx
• Lilium pomponium
• Lychnophora pinaster
• Marrubium parviflorum
• Microglossa pyrifolia
• Monanthotaxis cauliflora
• Mosla chinensis
• Mosla scabra
• Mosla soochouensis
• Muntingia calabura
• Ononis angustissima
• Parthenium confertum
• Polemonium viscosum
• Polygonatum orientale
• Psathyrotes ramosissima
• Scleropyrum pentandrum
• Selliguea hastata
• Trifolium diffusum
• Uvaria rufa
• Veronica stricta
• Youngia japonica
• Zanthoxylum acuminatum subsp. juniperinum

Cross-Links

• PubChem: 471722
• NPASS: NPC239128
• ChEMBL: CHEMBL52676
• LOTUS: LTS0073587
• wikiData: Q27277625