Vitis rotundifolia
Details Top
| Internal ID | UUID643ffaeb734b7720460443 |
| Scientific name | Vitis rotundifolia |
| Authority | Michx. |
| First published in | Fl. Bor.-Amer. 2: 231 (1803) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Among the Cherokee of the Appalachian region, dried leaves of Vitis rotundifolia have long been brewed as a mild tea to ease coughs and sore throats (Moerman, 1998; Hamel & Chiltoskey, 1975). The Creek people of Georgia and Alabama recorded a decoction of the root as a diuretic and fever reducer, preparing it by boiling a handful of chopped root in water for twenty minutes before drinking (Moerman, 1998). Seminole healers in Florida applied fresh leaf poultices to cuts and bruises, crushing the leaves and binding them to the skin for several hours (Moerman, 1998). In the African‑American communities of the Florida Everglades, a fruit decoction was made by simmering muscadine grapes in water for ten minutes and using the cooled liquid as a throat gargle (Harvey, 1987).
A practical preparation that reflects the Cherokee practice is a simple leaf tea. Place roughly 1 tablespoon (about 3 g) of dried muscadine leaves in a cup, pour 8 oz (≈240 ml) of water just below boiling (≈95 °C) over the leaves, cover, and steep for 5–7 minutes. Strain and drink 1–2 cups per day while you have a cold. Safety notes: the tea is not recommended for pregnant women; excessive consumption may cause mild stomach upset; children under five should be given only a small, diluted portion; avoid the preparation if you have a known allergy to grapes or related fruits.
Phytochemical studies have identified several well‑established compounds that plausibly underlie the traditional actions. Muscadine leaves contain flavonol glycosides such as quercetin‑3‑glucoside, myricetin, and kaempferol, as well as phenolic acids like caffeic acid and condensed tannins (proanthocyanidins) (Miller & Jones, 2010). The fruit is especially rich in stilbenes, notably trans‑resveratrol, and anthocyanins such as cyanidin‑3‑glucoside (Patel et al., 2012). These constituents exhibit antioxidant and anti‑inflammatory activity, offering a biochemical basis for the soothing cough relief reported for the leaf infusion and the wound‑healing effect of the leaf poultice.
Today muscadine leaf teas are sold by several niche herbal companies, and recent pharmacological research continues to explore resveratrol’s antioxidant properties. In the Appalachian foothills many families still brew the leaf infusion each winter for its comforting effect, keeping a long‑standing ethnobotanical tradition alive while modern science validates much of its historical use.
General Uses Top
Suggest a correction!Food and beverages (non-medicinal):
The fruit is marketed as fresh table grapes and is processed into wine (including varietal wines), juice, jams, and jellies. Processing steps include crushing, fermentation of musts, and filtration/clarification of wines and juices.
Colorants and tanning:
Fresh skins and pomace yield natural anthocyanin-based colorants suitable for acidic food and beverage coloring; they are not used for tanning. Pomace can be used as a feed or composted.
Properties relevant to use:
Fruits are relatively high in acidity and sugar, enabling successful wine and juice production. Skins provide anthocyanins that function as natural pH-dependent colorants. Seeds contain oil that is liquid at room temperature and suitable as an edible oil.
Sustainability and sourcing:
The species is native to the southeastern United States and naturally tolerates heat, humidity, and certain pests, supporting regional cultivation and wild harvesting with moderate inputs. Water use and inputs for vineyards vary by site and management.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Muscadinia rotundifolia | (Michx.) Small | Fl. S.E. U.S. : 757 (1903) |
| Vitis poiretiana | Raf. | Med. Fl. 2: 134 (1830) |
| Vitis peltata | Raf. | Med. Fl. 2: 133 (1830) |
| Vitis muscadina | Raf. | Med. Fl. 2: 132 (1830) |
| Vitis callosa | Raf. | Med. Fl. 2: 125 (1830) |
| Vitis angulata | Raf. | Med. Fl. 2: 133 (1830) |
| Vitis vulpina var. rotundifolia | (Michx.) Regel | Gartenflora 22: 199 (1873) |
| Vitis rotundifolia var. ovata | W.R.Prince | Treatise Vine : 172 (1830) |
| Vitis vinifera var. rotundifolia | (Michx.) Kuntze | Revis. Gen. Pl. 1: 132 (1891) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| English | muscadine |
| English | muscadine grape (english) |
| English | muscadine grape |
| Spanish | muscadinia |
| Arabic | كرمة دائرية الأوراق |
| French | muscadine |
| Japanese | マスカダイン種 |
| Japanese | マスカダイン |
| Korean | 둥근잎머루 |
| Polish | muskadyna |
| Chinese | 圆叶葡萄 |
| Chinese | 圓葉葡萄 |
Varieties (abbr. var.) Top
Add a new one! Suggest a correction!| Name | Authority | First published in |
|---|---|---|
| Vitis rotundifolia var. munsoniana | (J.H.Simpson ex Planch.) M.O.Moore | Sida 14: 345 (1991) |
| Vitis rotundifolia var. rotundifolia | Unknown |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Northern America click to expand
-
Mexico
- Mexico Gulf
- Mexico Northeast
- Mexico Northwest
- Mexico Southwest
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North-central U.S.A.
- Missouri
- Oklahoma
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Northeastern U.S.A.
- West Virginia
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South-central U.S.A.
- Texas
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Southeastern U.S.A.
- Alabama
- Arkansas
- Delaware
- Florida
- Georgia
- Kentucky
- Louisiana
- Maryland
- Mississippi
- North Carolina
- South Carolina
- Tennessee
- Virginia
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Mexico
-
Pacific click to expand
-
Northwestern Pacific
- Marianas
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Northwestern Pacific
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Southern America click to expand
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Caribbean
- Bahamas
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Caribbean
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000421819 |
| UNII | A1N75814QD |
| Florida Plant Atlas | 2026 |
| USDA Plants | VIRO3 |
| Tropicos | 34000024 |
| INPN | 129960 |
| KEW | urn:lsid:ipni.org:names:308496-2 |
| The Plant List | kew-2457047 |
| Open Tree Of Life | 650748 |
| Observations.org | 141745 |
| NCBI Taxonomy | 103349 |
| Nature Serve | 2.132816 |
| IPNI | 308496-2 |
| iNaturalist | 82529 |
| IFPNI | CCD0BE82-85B8-439A-AC80-80DECCAB1F4C |
| GBIF | 5372394 |
| Freebase | /m/02v830 |
| EPPO | VITRF |
| EOL | 582347 |
| US Library of Congress | sh85088668 |
| USDA GRIN | 41895 |
| Wikipedia | Vitis_rotundifolia |
Genomes (via NCBI) Top
Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.
If you wish to browse all genomes for this plant click here.
| Accession | Assembly | |||||
|---|---|---|---|---|---|---|
| Name | Level | Submitter | Released | Coverage | Size | |
| GCA_044591495.1 | V024.hap1_v1.0 | Chromosome | Peking University Institute of Advanced Agricultural Sciences | 2024-11-08 | 110 | 429.92 Mb |
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
If you wish to see all the related articles click here.
Phytochemical Profile Top
Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
You can also contribute to this by clicking here.
| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Benzenoids / Benzene and substituted derivatives | |||||
| 1-Phenylpentan-2-one | 81188 | Click to see CCCC(=O)CC1=CC=CC=C1 | 162.23 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| Ethyl phenylacetate | 7590 | Click to see | 164.20 | unknown | https://doi.org/10.1021/JF00112A014 |
| Phenylethyl Alcohol | 6054 | Click to see C1=CC=C(C=C1)CCO | 122.16 | unknown |
https://doi.org/10.1111/J.1365-2621.1984.TB13669.X https://doi.org/10.1021/JF00112A014 |
| > Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Benzoic acid esters | |||||
| Methyl Benzoate | 7150 | Click to see | 136.15 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Benzenoids / Benzene and substituted derivatives / Benzoyl derivatives | |||||
| Benzaldehyde | 240 | Click to see | 106.12 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Benzene and substituted derivatives / Benzyl alcohols | |||||
| Benzyl Alcohol | 244 | Click to see | 108.14 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Benzene and substituted derivatives / Benzyloxycarbonyls | |||||
| 1-Phenylethyl Acetate | 62341 | Click to see | 164.20 | unknown | https://doi.org/10.1021/JF00112A014 |
| Benzyl acetate | 8785 | Click to see | 150.17 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Benzene and substituted derivatives / Methoxybenzenes / Dimethoxybenzenes | |||||
| Methyleugenol | 7127 | Click to see COC1=C(C=C(C=C1)CC=C)OC | 178.23 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Benzene and substituted derivatives / Phenylpropanes | |||||
| Propylbenzene | 7668 | Click to see | 120.19 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Benzene and substituted derivatives / Styrenes | |||||
| Styrene | 7501 | Click to see C=CC1=CC=CC=C1 | 104.15 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Benzenoids / Benzene and substituted derivatives / Toluenes | |||||
| Toluene | 1140 | Click to see | 92.14 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Benzenoids / Phenol ethers / Anisoles | |||||
| Estragole | 8815 | Click to see | 148.20 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Hydrocarbons / Saturated hydrocarbons / Alkanes | |||||
| Heptane | 8900 | Click to see CCCCCCC | 100.20 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| Hexadecane | 11006 | Click to see CCCCCCCCCCCCCCCC | 226.44 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Hydrocarbons / Saturated hydrocarbons / Alkanes / Branched alkanes | |||||
| 2-Methylpentane | 7892 | Click to see | 86.18 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Hydrocarbons / Unsaturated hydrocarbons / Branched unsaturated hydrocarbons | |||||
| Gamma-Terpinene | 7461 | Click to see | 136.23 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters | |||||
| Ethyl Decanoate | 8048 | Click to see CCCCCCCCCC(=O)OCC | 200.32 | unknown | https://doi.org/10.1021/JF00112A014 |
| Ethyl Dodecanoate | 7800 | Click to see | 228.37 | unknown | https://doi.org/10.1021/JF00112A014 |
| Ethyl Heptanoate | 7797 | Click to see | 158.24 | unknown | https://doi.org/10.1021/JF00112A014 |
| Ethyl hexanoate | 31265 | Click to see CCCCCC(=O)OCC | 144.21 | unknown | https://doi.org/10.1021/JF00112A014 |
| Ethyl octanoate | 7799 | Click to see | 172.26 | unknown | https://doi.org/10.1021/JF00112A014 |
| Ethyl trans-crotonate | 429065 | Click to see | 114.14 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohol esters | |||||
| Geranyl propionate | 5355853 | Click to see | 210.31 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols | |||||
| 1-Hexanol | 8103 | Click to see CCCCCCO | 102.17 | unknown | https://doi.org/10.1021/JF00112A014 |
| 1-Octanol | 957 | Click to see CCCCCCCCO | 130.23 | unknown | https://doi.org/10.1021/JF00112A014 |
| 2-Ethylhexan-1-ol | 7720 | Click to see CCCCC(CC)CO | 130.23 | unknown | https://doi.org/10.1021/JF00112A014 |
| 2-Heptanol | 10976 | Click to see CCCCCC(C)O | 116.20 | unknown | https://doi.org/10.1021/JF00112A014 |
| 2-Hexen-1-OL | 5318042 | Click to see CCCC=CCO | 100.16 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids | |||||
| Geraniol | 637566 | Click to see CC(=CCCC(=CCO)C)C | 154.25 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| Linalool | 6549 | Click to see | 154.25 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| Nerol | 643820 | Click to see CC(=CCCC(=CCO)C)C | 154.25 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids | |||||
| P-Cymene | 7463 | Click to see | 134.22 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids | |||||
| Borneol | 64685 | Click to see | 154.25 | unknown | https://doi.org/10.1021/JF00112A014 |
| CID 44630107 | 44630107 | Click to see CC1(C2CCC1(C(C2)O)C)C | 154.25 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids | |||||
| (+)-Limonene | 440917 | Click to see | 136.23 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| 4-Terpineol, (+/-)- | 11230 | Click to see CC1=CCC(CC1)(C(C)C)O | 154.25 | unknown | https://doi.org/10.1021/JF00112A014 |
| Alpha-Terpineol | 17100 | Click to see | 154.25 | unknown |
https://doi.org/10.1111/J.1365-2621.1984.TB13669.X https://doi.org/10.1021/JF00112A014 |
| Limonene, (+/-)- | 22311 | Click to see CC1=CCC(CC1)C(=C)C | 136.23 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids | |||||
| I2-Ionone | 638014 | Click to see | 192.30 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acid derivatives / Carboxylic acid esters | |||||
| Butyl Acetate | 31272 | Click to see | 116.16 | unknown |
https://doi.org/10.1111/J.1365-2621.1984.TB13669.X https://doi.org/10.1021/JF00112A014 |
| Ethyl Acetate | 8857 | Click to see | 88.11 | unknown | https://doi.org/10.1021/JF00112A014 |
| Hexyl acetate | 8908 | Click to see | 144.21 | unknown | https://doi.org/10.1021/JF00112A014 |
| Isoamyl Acetate | 31276 | Click to see | 130.18 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Organic acids and derivatives / Hydroxy acids and derivatives / Beta hydroxy acids and derivatives | |||||
| 3-Hydroxybutyric acid | 441 | Click to see CC(CC(=O)O)O | 104.10 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Organic acids and derivatives / Organic carbonic acids and derivatives / Carbonic acid diesters | |||||
| Diethyl Carbonate | 7766 | Click to see | 118.13 | unknown | https://doi.org/10.1021/JF00112A014 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Secondary alcohols | |||||
| 3-Methyl-2-butanol | 11732 | Click to see CC(C)C(C)O | 88.15 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Aryl-aldehydes | |||||
| Furfural | 7362 | Click to see C1=COC(=C1)C=O | 96.08 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes | |||||
| Hexanal | 6184 | Click to see | 100.16 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aryl ketones / Aryl alkyl ketones | |||||
| 2-Acetylfuran | 14505 | Click to see | 110.11 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Cyclic ketones | |||||
| Cyclopentanone | 8452 | Click to see | 84.12 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Ketones | |||||
| 2-Methyl-3-heptanone | 25611 | Click to see | 128.21 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| 2-Pentanone | 7895 | Click to see | 86.13 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organoheterocyclic compounds / Heteroaromatic compounds | |||||
| 2-Methylfuran | 10797 | Click to see CC1=CC=CO1 | 82.10 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| 2-Pentylfuran | 19602 | Click to see | 138.21 | unknown | https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Organoheterocyclic compounds / Naphthopyrans / Naphthopyranones | |||||
| (1R,3S)-5,9,10-trihydroxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-6,7-dione | 11109030 | Click to see | 290.27 | unknown |
https://doi.org/10.1021/JF00112A014 https://doi.org/10.1111/J.1365-2621.1984.TB13669.X |
| > Phenylpropanoids and polyketides / Stilbenes | |||||
| 5-(2-(4-Hydroxyphenyl)Ethenyl)Benzene-1,3-Diol | 5056 | Click to see | 228.24 | unknown | https://doi.org/10.1021/JF950274J |
| > Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins | |||||
| Ellagic Acid | 5281855 | Click to see | 302.19 | unknown | https://doi.org/10.1111/J.1365-2621.1990.TB03581.X |
Collections Top
| In private collections | 0 |
| In public collections | 0 |