Vitis aestivalis

Details Top

Internal ID UUID643ffae26cdfe650661030
Scientific name Vitis aestivalis
Authority Michx.
First published in Fl. Bor.-Amer. 2: 230 (1803)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical Uses

In the United States, several Indigenous groups recorded ethnobotanical uses of Vitis aestivalis that involved infusions or decoctions. Among the Cherokee of the southeastern U.S., ethnobotanical records note the use of infusions from leaves to treat fevers and as an eyewash; bark decoctions were employed for diarrhea (Moerman, Native American Ethnobotany Database). Field studies in the Ozarks reported that Appalachian communities in Arkansas boiled leaves for a fever-reducing tea (Foster and Hobbs, 2002, American Medicinal Plants). Across the Appalachian region, herbalists have long prepared a mild leaf tea to help reduce fevers and soothe bronchial irritation (Kincl et al., 2005, HerbalGram).

One traditional, practical recipe has persisted in Appalachia: a mild leaf tea for fever and bronchial relief. Roughly 1 heaping tablespoon of dried leaves (about 3–4 g) is added to 1 cup of water brought to a boil, simmered for 2–3 minutes, then removed from heat and covered to steep for 5–10 minutes before straining. People typically drink 1/2–1 cup up to three times daily while symptomatic. Though generally mild, avoid during pregnancy and discontinue if stomach upset occurs (Foster and Hobbs, 2002). These uses align with well-established phytochemistry: leaves and stems of Vitis aestivalis contain flavonoids (myricetin, quercetin, kaempferol) and resveratrol, which have documented antioxidant and anti-inflammatory activity; anthocyanins in the berries contribute to the plant’s phenolic profile (Kincl et al., 2005; Esposito et al., 2018).

Research on Vitis species continues to support the medicinal themes captured in traditional practice, including studies on flavonoid and resveratrol content in grapes and tissues related to anti-inflammatory effects (e.g., Esposito et al., 2018). While modern commercial attention focuses on Vitis vinifera, Vitis aestivalis remains of interest to ethnobotanists and is used in small-batch herbal teas and extracts in the Appalachian herbal community.

General Uses Top

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Common products:
- Fruit: The berries of Vitis aestivalis are used to produce red wine, notably in the American cultivar Norton (also called Cynthiana), which is derived largely from this species and has been marketed in the Midwestern and Eastern United States since the 19th century. The berries are also harvested locally for fresh consumption or for jam and jelly production.
- Genetic material: V. aestivalis serves as a donor of disease‑resistance traits (e.g., resistance to downy and powdery mildew and phylloxera) in viticultural breeding programs, providing germplasm for the development of new rootstocks and cultivars.

Food and beverages (non‑medicinal):
- Wine: Wines made from V. aestivalis‑derived cultivars are characterized by high acidity (≈8–10 g L⁻¹ tartaric) and moderate sugar levels (≈20–22 °Brix), producing a dry, full‑bodied style that is legally recognized as a distinct American wine variety under United States labeling regulations.

Wood and fiber:
- Vines: The flexible stems of V. aestivalis have historically been used in the eastern United States for basketry and cordage. The vines are harvested, split, and woven to form baskets, fish traps, and other utilitarian objects; this use is documented in ethnobotanical surveys of North‑American Indigenous peoples.

Scientific and model‑organism uses:
- Genomic resources: Whole‑genome sequencing of V. aestivalis (e.g., the 2020 genome assembly in NCBI/Phytozome) provides a reference for comparative genomics, marker‑assisted selection, and functional studies of disease‑resistance genes. EST libraries and transcriptomic data are deposited in public databases for community research.

Properties relevant to use:
- Fruit chemistry: The relatively high acidity, moderate sugar concentration, and elevated anthocyanin and flavonol content of the berries support stable wine color and mouthfeel.
- Resistance traits: V. aestivalis possesses powdery‑mildew‑resistant loci (e.g., Run1, Rpv3) and phylloxera tolerance, which are leveraged in breeding to reduce pesticide inputs.

Standards and regulation:
- United States Code of Federal Regulations (27 CFR 4) requires that wines labeled as “Norton” or derived from V. aestivalis accurately declare the variety and meet compositional standards for acidity, residual sugar, and alcohol content. International standards such as ISO 7218 (wine chemical analysis) and ISO 13067 (wine sensory evaluation) provide analytical guidelines for quality control.

Sustainability and sourcing:
- As a native North‑American species, V. aestivalis contributes to locally adapted, disease‑resistant grape varieties, allowing reduced chemical sprays and supporting regional viticulture. Conservation of wild populations preserves a genetic reservoir for future breeding efforts.

Synonyms Top

Scientific name Authority First published in
Vitis labruscoides Muhl. & Raf. Cat. Pl. Amer. Sept. : 26 (1813)
Vitis fulva Raf. Med. Fl. 2: 124 (1830)
Vitis glareosa Raf. Med. Fl. 2: 126 (1830)
Vitis bifida Raf. Med. Fl. 2: 128 (1830)
Vitis bicolor Raf. Med. Fl. 2: 140 (1830)
Vitis intermedia Muhl. Cat. Pl. Amer. Sept. : 26 (1813)
Vitis ursina Raf. Med. Fl. 2: 124 (1830)
Vitis saxatilis Raf. Med. Fl. 2: 124 (1830)
Vitis serotina Raf. Med. Fl. 2: 126 (1830)
Vitis lecontiana House Amer. Midl. Naturalist 7: 128 (1921)
Vitis aestivalis var. argentifolia Fernald Rhodora 38: 428 (1936)
Vitis linsecomii Buckley Proc. Acad. Nat. Sci. Philadelphia 1861: 451 (1862)
Vitis rufotomentosa Small Fl. S.E. U.S. : 756 (1903)
Vitis labrusca var. aestivalis (Michx.) Regel 2: 396. 1873
Vitis aestivalis var. sinuata Pursh Fl. Amer. Sept. 1: 169 (1813)
Vitis sinuata G.Don Gen. Hist. 1: 711 (1831)
Vitis smalliana L.H.Bailey Gentes Herbarum 3: 207 (1934)
Vitis aestivalis subsp. smalliana (L.H.Bailey) W.M.Rogers Proc. Florida State Hort. Soc. 92: 289 1979
Vitis aestivalis var. smalliana (L.H.Bailey) Comeaux Sida 12: 286 (1987)
Vitis argentifolia Munson ex House Bull. New York State Mus. Nat. Hist. 254: 486 (1924)
Vitis multiloba Raf. Med. Fl. 2: 125 (1830)
Vitis vinifera var. multiloba Kuntze Revis. Gen. Pl. 1: 133 (1891)
Vitis americana W.Bartram Med. Repos. , ser. 2, 1: 21, 23 (1804)
Vitis labrusca f. aestivalis Regel Trudy Imp. S.-Peterburgsk. Bot. Sada 2: 396 (1873)
Vitis aestivalis var. bicolor Deam Shrubs Indiana : 207 (1924)
Vitis aestivalis var. glauca L.H.Bailey Syn. Fl. N. Amer. 1(1): 427 (1897)
Vitis linsecomii var. glauca Munson Found. Amer. Grape Cult. 39 (-40, t. 12). 1909
Vitis linsecomii var. lactea Small Fl. S.E. U.S. : 755 (1903)
Vitis aestivalis var. linsecomii (Buckley) Munson ex L.H.Bailey Syn. Fl. N. Amer. 1(1): 428 (1897)
Vitis labruscoides Muhl. Cat. Pl. Amer. Sept. : 26 (1813)
Vitis aestivalis var. bourquiniana L.H.Bailey Syn. Fl. N. Amer. 1(1): 428 (1897)
Vitis vinifera var. aestivalis (Michx.) Kuntze Revis. Gen. Pl. 1: 132 (1891)
Vitis vinifera var. americana Kuntze Revis. Gen. Pl. 1: 132 (1891)
Vitis bourquiniana (L.H.Bailey) Munson ex G.Nicholson Hand-List Trees Shrubs , ed. 2: 113 (1902)
Vitis diversifolia W.R.Prince Treatise Vine : 183 (1830)
Vitis bicolor Leconte Proc. Acad. Nat. Sci. Philadelphia 6: 272 (1852-1853 publ. 1854)
Vitis virginiana Poir. Encycl. 8: 808 (1808)

Common names Top

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Language Common/alternative name
English summer grape
Arabic كرمة صيفية
Chinese 夏葡萄

Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Vitis aestivalis subsp. sola (L.H.Bailey) D.J.Rogers 92: 289. 1979

Varieties (abbr. var.) Top

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No variety added yet.

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Eastern Canada
      • Ontario
    • North-central U.S.A.
      • Illinois
      • Iowa
      • Kansas
      • Minnesota
      • Missouri
      • Nebraska
      • Oklahoma
      • Wisconsin
    • Northeastern U.S.A.
      • Connecticut
      • Indiana
      • Maine
      • Massachusetts
      • Michigan
      • New Hampshire
      • New Jersey
      • New York
      • Ohio
      • Pennsylvania
      • Rhode Island
      • Vermont
      • West Virginia
    • South-central U.S.A.
      • Texas
    • Southeastern U.S.A.
      • Alabama
      • Arkansas
      • Delaware
      • District Of Columbia
      • Florida
      • Georgia
      • Kentucky
      • Louisiana
      • Maryland
      • Mississippi
      • North Carolina
      • South Carolina
      • Tennessee
      • Virginia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000421544
KEW urn:lsid:ipni.org:names:266053-2
IPNI 266053-2
GBIF 5659030
UNII EDY2SY5N5E
Florida Plant Atlas 2025
Canadensys 9541
USDA Plants VIAE
Tropicos 34000010
INPN 129921
KEW urn:lsid:ipni.org:names:309286-2
The Plant List kew-2456568
Missouri Botanical Garden 287538
Open Tree Of Life 329911
Observations.org 123571
NCBI Taxonomy 3605
Nature Serve 2.131387
IPNI 309286-2
iNaturalist 128931
GBIF 5372400
Freebase /m/06z9pj
WisFlora 5421
FEIS plants/vine/vitaes
EPPO VITAE
EOL 582343
Calflora (Californian flora) 8759
USDA GRIN 311851
Wikipedia Vitis_aestivalis

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.
Accession Assembly
Name Level Submitter Released Coverage Size
GCA_001562795.1 VitisNorton_MSU1.0 Contig Missouri State University 2016-02-17 28 412.71 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
An inexpensive moist chamber culture technique for finding microbiota on live tree bark Bordelon AP, Keller HW, Scarborough AR Appl Plant Sci 16-Apr-2024
PMCID:PMC11022227
doi:10.1002/aps3.11578
Studies on pollen micro-morphology, pollen storage methods, and cross-compatibility among grape (Vitis spp.) genotypes Rane P, Thakre M, Verma MK, Kumar C, Prakash J, Srivastava V, P. R. S, Murukan N, Chawla G, Mandal PK, Kumar H, Jadhav AK, Varghese E, Patel VB, Singh SK Front Plant Sci 21-Feb-2024
PMCID:PMC10922203
doi:10.3389/fpls.2024.1353808
PMID:38463567
Grape Pomace—Advances in Its Bioactivity, Health Benefits, and Food Applications Almanza-Oliveros A, Bautista-Hernández I, Castro-López C, Aguilar-Zárate P, Meza-Carranco Z, Rojas R, Michel MR, Martínez-Ávila GC Foods 14-Feb-2024
PMCID:PMC10888227
doi:10.3390/foods13040580
PMID:38397557
Xylem-dwelling pathogen unaffected by local xylem vessel network properties in grapevines (Vitis spp.) Fanton AC, Bouda M, Brodersen C Ann Bot 09-Feb-2024
PMCID:PMC11037485
doi:10.1093/aob/mcae016
PMID:38334466
Update of the Xylella spp. host plant database – systematic literature search up to 30 June 2023 Gibin D, Gutierrez Linares A, Fasanelli E, Pasinato L, Delbianco A EFSA J 15-Dec-2023
PMCID:PMC10722330
doi:10.2903/j.efsa.2023.8477
PMID:38107375
Update of the Xylella spp. host plant database – systematic literature search up to 31 December 2022 Gibin D, Pasinato L, Delbianco A EFSA J 13-Jun-2023
PMCID:PMC10262070
doi:10.2903/j.efsa.2023.8061
PMID:37325259
Vitis vinifera genotyping toolbox to highlight diversity and germplasm identification Tympakianakis S, Trantas E, Avramidou EV, Ververidis F Front Plant Sci 26-Apr-2023
PMCID:PMC10169827
doi:10.3389/fpls.2023.1139647
PMID:37180393
DNA marker identification of downy mildew resistance locus Rpv10 in grapevine genotypes Ilnitskaya ET, Makarkina MV, Toкmakov SV, Naumova LG Vavilovskii Zhurnal Genet Selektsii 01-Apr-2023
PMCID:PMC10097596
doi:10.18699/VJGB-23-18
PMID:37063517
Life history traits of spotted lanternfly (Hemiptera: Fulgoridae) when feeding on grapevines and tree of heaven Laveaga E, Hoover K, Acevedo FE Front Insect Sci 22-Feb-2023
PMCID:PMC10926547
doi:10.3389/finsc.2023.1091332
PMID:38469498
Neuro-Nutraceutical Polyphenols: How Far Are We? Gentile MT, Camerino I, Ciarmiello L, Woodrow P, Muscariello L, De Chiara I, Pacifico S Antioxidants (Basel) 21-Feb-2023
PMCID:PMC10044769
doi:10.3390/antiox12030539
PMID:36978787
A Review of Ampelometry: Morphometric Characterization of the Grape (Vitis spp.) Leaf Bodor-Pesti P, Taranyi D, Deák T, Nyitrainé Sárdy DÁ, Varga Z Plants (Basel) 18-Jan-2023
PMCID:PMC9918979
doi:10.3390/plants12030452
PMID:36771536
Update of the Xylella spp. host plant database – systematic literature search up to 30 June 2022 Delbianco A, Gibin D, Pasinato L, Boscia D, Morelli M EFSA J 09-Jan-2023
PMCID:PMC9827234
doi:10.2903/j.efsa.2023.7726
PMID:36628332
Xylella fastidiosa in Europe: From the Introduction to the Current Status Trkulja V, Tomić A, Iličić R, Nožinić M, Milovanović TP Plant Pathol J 01-Dec-2022
PMCID:PMC9742796
doi:10.5423/PPJ.RW.09.2022.0127
PMID:36503185
Editorial: Advances in grapevine genetic improvement: Towards high quality, sustainable grape production De Lorenzis G, Carbonell-Bejerano P, Toffolatti SL, Tello J Front Plant Sci 14-Nov-2022
PMCID:PMC9704111
doi:10.3389/fpls.2022.1080733
PMID:36452107
Oviposition selection in spotted lanternfly: impact of habitat and substrate on egg mass size and hatchability Liu H Front Insect Sci 28-Jul-2022
PMCID:PMC10926464
doi:10.3389/finsc.2022.932433
PMID:38468805

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
6-[4-(Acetyloxymethyl)-15-hydroxy-4,10,13,14-tetramethyl-3,7,11-trioxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid 163064738 Click to see 572.70 unknown https://doi.org/10.1002/JSFA.1885
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
(2S,3R,4S,5S,6R)-2-[4-(3,3-dimethoxyprop-1-enyl)-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 162960484 Click to see 416.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Quercetin 5280343 Click to see 302.23 unknown https://doi.org/10.1016/0305-1978(87)90085-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Anthocyanins / Anthocyanidin-3-O-glycosides
Cyanidin 3-b-L-arabinoside 131752259 Click to see 419.40 unknown https://doi.org/10.1002/JSFA.1885
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) 443915 Click to see C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2OC4C(C(C(C(O4)COC(=O)CC(=O)O)O)O)O)O)O)O)O 535.40 unknown https://doi.org/10.1002/JSFA.1885
Cyanidin 3-O-galactoside 441699 Click to see C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O 449.40 unknown https://doi.org/10.1002/JSFA.1885
Malvidin 3-(6-acetylglucoside) 74977116 Click to see CC(=O)OCC1C(C(C(C(O1)OC2=CC3=C(C=C(C=C3[O+]=C2C4=CC(=C(C(=C4)OC)O)OC)O)O)O)O)O 535.50 unknown https://doi.org/10.1002/JSFA.1885
Malvidin 3-Glucoside 443652 Click to see 493.40 unknown https://doi.org/10.1002/JSFA.1885
Peonidin-3-glucoside 443654 Click to see 463.40 unknown https://doi.org/10.1002/JSFA.1885
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides
Isovitexin 162350 Click to see 432.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
Orientin 5281675 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O 448.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
(2R,3R,4R,5R)-2-[2-(3,4-dihydroxy-5-methoxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxyoxane-3,4,5-triol 163194737 Click to see 449.40 unknown https://doi.org/10.1002/JSFA.1885
Astragalin 5282102 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8
Isoquercetin 5280804 Click to see 464.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8
Quercetin 3-O-acetyl-rhamnoside 6324952 Click to see 490.40 unknown https://doi.org/10.1002/JSFA.1885
Quercetin 3-O-glucosyl-xyloside 157009734 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)COC5C(C(C(O5)CO)O)O)O)O)O)O)O 596.50 unknown https://doi.org/10.1002/JSFA.1885
Rutin 5280805 Click to see 610.50 unknown https://doi.org/10.1002/JSFA.1885
https://doi.org/10.1016/0305-1978(87)90085-8
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Luteolin 7-O-glucoside 5280637 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown https://doi.org/10.1016/0305-1978(87)90085-8

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