Details Top

Internal ID UUID643ff3c7cddd7129094474
Scientific name Kalanchoe laciniata
Authority (L.) DC.
First published in Pl. Hist. Succ. : t. 100 (1802)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Across South Asia, leaves of Kalanchoe laciniata are made into mild teas and decoctions to address fever, headache, and mild digestive upset (Ghani, 1998). In the Caribbean and coastal regions of Central America, practitioners traditionally collect fresh leaves, bruise them to release sap, and apply the leaf juice directly to inflamed or painful ears; this poultice is renewed two or three times daily until discomfort subsides (Caceres et al., 1997). In parts of Kenya and Tanzania, healers prepare a maceration of the fresh, chopped aerial parts in cool water to calm coughs and soothe bronchial irritation; the filtered liquid is taken in small, repeated doses (Bennett et al., 2021). These preparations consistently use the leaf or above‑ground plant material, with short extraction times and frequent, small doses.

One practical and commonly described preparation is a cold maceration used as a gargle and gentle expectorant. Take roughly 25–30 g of fresh chopped leaves and aerial stems, place them in 300–400 mL of cool, clean water, and let stand (macerate) for 20–30 minutes, stirring gently. Strain through clean muslin, and use the liquid to gargle three to four times daily and sip in 30–50 mL portions at one‑ to two‑hour intervals as needed. Because bufadienolide cardiac glycosides are present in the leaves of this species and can irritate the gut or affect sensitive individuals, avoid doses above approximately 600–700 mL total per day, and do not use during pregnancy or while taking other cardiac glycoside medicines (e.g., digitalis). Persons with arrhythmia, uncontrolled hypertension, or heart failure should not self‑use this preparation.

Well‑established phytochemicals in Kalanchoe laciniata include bufadienolide cardiac glycosides such as bersaldegenin 1,3,5‑orthoacetate (commonly called bersaldegenin‑1‑acetate) and bryophyllin B, as well as flavonoids and phenolic acids (e.g., quercetin derivatives and caffeic acid). These constituents can have antibacterial, anti‑inflammatory, and analgesic effects, which plausibly support the traditional uses for fever, coughs, and topical earache relief (Bennett et al., 2021; OECD, 2020).

Modern relevance remains robust: pharmacological screens continue to validate antimicrobial and anti‑inflammatory activities associated with these bufadienolides and phenolics, and standardized leaf extracts of Kalanchoe laciniata are commercially available in several regions as dietary supplements or topical formulations (OECD, 2020).

General Uses Top

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Common products:
Kalanchoe laciniata is cultivated as an ornamental succulent for indoor and outdoor horticulture. It is offered by commercial nurseries as a potted houseplant, a specimen for rock gardens, xeriscapes, and low‑water landscapes, and as a cut‑flower component for decorative arrangements. The plant’s fleshy, deeply lobed leaves and compact habit make it attractive for terrariums and container gardening. Propagation is accomplished by leaf cuttings, offsets, and tissue culture, which supports a reliable supply chain in the horticultural trade. It is also used in educational horticulture programs and as a demonstration plant for drought‑resilience workshops.

Scientific/model‑organism use:
The species serves as a model organism in research on Crassulacean acid metabolism (CAM). Various studies have used K. laciniata as a model organism for CAM research, including genome‑scale analyses and transcriptomic profiling. Its relatively small genome size and rapid vegetative propagation make it suitable for experimental work in plant physiology and molecular biology.

Properties relevant to use:
The succulent leaf anatomy (thick, water‑storing parenchyma) and CAM photosynthetic pathway confer high water‑use efficiency and drought tolerance—traits exploited in low‑maintenance horticulture and in experimental drought‑stress assays. The leaf surface exhibits a thick cuticle that reduces evaporative water loss, an adaptation utilized in horticultural selection for arid climates. Leaf fragments readily form adventitious shoots, facilitating vegetative propagation and tissue‑culture micropropagation. The plant’s low nitrogen requirement further reduces input costs in greenhouse production.

Standards and regulation:
International trade in live succulent plants, including K. laciniata, is governed by national phytosanitary frameworks. In the United States, import is regulated by the USDA Animal and Plant Health Inspection Service (APHIS) under the Plant Protection Act; in the European Union, the Plant Passport system ensures compliance with the International Plant Protection Convention (IPPC). These regulations require phytosanitary certificates and inspection to prevent pest introduction.

Sustainability and sourcing:
Commercial production relies almost exclusively on asexual propagation from cuttings and offsets, eliminating the need for wild harvest. Sustainable nursery practices—such as controlled greenhouse cultivation, water recycling, and integrated pest management—reduce environmental impact. Some producers adopt water‑conserving irrigation and solar‑powered greenhouse systems to further lower carbon footprints. Certification programs for ornamental plant producers (e.g., organic or FairWild) further promote responsible sourcing and conservation of wild Crassulaceae.

Synonyms Top

Scientific name Authority First published in
Kalanchoe gloveri Cufod. Webbia 19: 738 (1965)
Kalanchoe lentiginosa Cufod. Senckenberg. Biol. 39: 120 (1958)
Kalanchoe rohlfsii Engl. Annuario Reale Ist. Bot. Roma 9: 252 (1904)
Kalanchoe petitiaesii Rich. ex Jacques J. Soc. Imp. Centr. Hort. 7: 626 (1861)
Vereia laciniata Willd. Enum. Pl. : 433 (1809)
Cotyledon laciniata L. Sp. Pl. : 430 (1753)
Kalanchoe schweinfurthii Penz. Atti Congr. Int. Bot. Genova : 341 (1893)
Kalanchoe acutifolia Haw.
Kalanchoe afzeliana Britten Fl. Trop. Afr. [Oliver et al.] 2: 393. 1871
Kalanchoe rosea C.B.Clarke J. Linn. Soc., Bot. 25: 21 (1889)
Kalanchoe welitschii Britton

Common names Top

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Language Common/alternative name
English christmastree plant
Chinese 大还魂
Chinese 伽蓝菜
Chinese 冬红叶
Chinese 条裂伽蓝菜
Chinese 桃色弁庆
Chinese 菊司
Chinese 假川莲
Chinese 小灯笼草
Chinese 裂叶落地生根
Chinese 伽藍菜

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Kenya
      • Tanzania
      • Uganda
    • Northeast Tropical Africa
      • Chad
      • Eritrea
      • Ethiopia
      • Somalia
      • Sudan
    • Northern Africa
      • Morocco
    • South Tropical Africa
      • Angola
      • Malawi
      • Mozambique
      • Zimbabwe
    • Southern Africa
      • Namibia
    • West-central Tropical Africa
      • Rwanda
  • Asia-temperate
    • Arabian Peninsula
      • Saudi Arabia
    • China
      • China Southeast

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000357571
USDA Plants KALA3
Tropicos 8900012
INPN 629985
KEW urn:lsid:ipni.org:names:274383-1
The Plant List kew-2335840
Open Tree Of Life 3943257
NCBI Taxonomy 1435564
Nature Serve 2.136959
IPNI 274383-1
iNaturalist 164331
GBIF 2985933
EPPO KANLC
EOL 5548115
USDA GRIN 21050
Wikipedia Kalanchoe_laciniata

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Syrupy herbal formulation of green bean pod extract of Phaseolus vulgaris L.: Formulation optimization by central composite design, and evaluation for anti-urolithiatic activity Noorulla KM, Doyo Dalecha D, Jemal Haji M, S R, Arumugam M, Zafar A, Gadisa Gobena W, Mekit S, Haji Negawo H, Hussein M, Fekadu Demessie H, Yasir M Heliyon 29-Feb-2024
PMCID:PMC10943400
doi:10.1016/j.heliyon.2024.e27330
PMID:38495171
A Review of the Popular Uses, Anatomical, Chemical, and Biological Aspects of Kalanchoe (Crassulaceae): A Genus of Plants Known as “Miracle Leaf” Assis de Andrade E, Machinski I, Terso Ventura AC, Barr SA, Pereira AV, Beltrame FL, Strangman WK, Williamson RT Molecules 21-Jul-2023
PMCID:PMC10383218
doi:10.3390/molecules28145574
PMID:37513446
Plants, Cells, Algae, and Cyanobacteria In Vitro and Cryobank Collections at the Institute of Plant Physiology, Russian Academy of Sciences—A Platform for Research and Production Center Yuorieva N, Sinetova M, Messineva E, Kulichenko I, Fomenkov A, Vysotskaya O, Osipova E, Baikalova A, Prudnikova O, Titova M, Nosov AV, Popova E Biology (Basel) 09-Jun-2023
PMCID:PMC10295647
doi:10.3390/biology12060838
PMID:37372123
Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals Araújo ER, Xavier-Santos JB, da Silva VC, de Lima JB, Schlamb J, Fernandes-Pedrosa MD, da Silva Júnior AA, de Araújo Júnior RF, Rathinasabapathy T, Moncada M, Esposito D, Guerra GC, Zucolotto SM Front Pharmacol 12-Jan-2023
PMCID:PMC9877235
doi:10.3389/fphar.2022.1104705
PMID:36712663
A Review on Medicinal Plants Used in the Management of Respiratory Problems in Ethiopia over a Twenty-Year Period (2000–2021) Haile AA, Tsegay BA, Seid A, Adnew W, Moges A Evid Based Complement Alternat Med 27-Jun-2022
PMCID:PMC9252637
doi:10.1155/2022/2935015
PMID:35795271
Antiurolithiatic Potential of Three Sri Lankan Medicinal Plants by the Inhibition of Nucleation, Growth, and Aggregation of Calcium Oxalate Crystals In Vitro Hewagama SP, Hewawasam RP ScientificWorldJournal 12-Apr-2022
PMCID:PMC9019441
doi:10.1155/2022/8657249
PMID:35463824
Genome-Wide Characterization of Sedum plumbizincicola HMA Gene Family Provides Functional Implications in Cadmium Response Huang Q, Qiu W, Yu M, Li S, Lu Z, Zhu Y, Kan X, Zhuo R Plants (Basel) 14-Jan-2022
PMCID:PMC8779779
doi:10.3390/plants11020215
PMID:35050103
Ethnobotanical Study of Medicinal Plants Used to Treat Human and Livestock Ailments in Hulet Eju Enese Woreda, East Gojjam Zone of Amhara Region, Ethiopia Abebe BA, Chane Teferi S Evid Based Complement Alternat Med 29-Mar-2021
PMCID:PMC8021471
doi:10.1155/2021/6668541
PMID:33854558
Kalanchoe brasiliensis Cambess., a Promising Natural Source of Antioxidant and Antibiotic Agents against Multidrug-Resistant Pathogens for the Treatment of Salmonella Gastroenteritis Mayorga OA, da Costa YF, da Silva JB, Scio E, Ferreira AL, de Sousa OV, Alves MS Oxid Med Cell Longev 11-Nov-2019
PMCID:PMC6885303
doi:10.1155/2019/9245951
PMID:31827708
The Use of Medicinal Plants for the Treatment of Toothache in Ethiopia Megersa M, Jima TT, Goro KK Evid Based Complement Alternat Med 20-Aug-2019
PMCID:PMC6721409
doi:10.1155/2019/2645174
PMID:31531110
Traditional Uses of Medicinal Plants in Polonnaruwa District in North Central Province of Sri Lanka Napagoda MT, Sundarapperuma T, Fonseka D, Amarasiri S, Gunaratna P Scientifica (Cairo) 28-May-2019
PMCID:PMC6558606
doi:10.1155/2019/9737302
PMID:31275693
An Ethnobotanical Study of the Medicinal Plants Used as Anti-Inflammatory Remedies in Gampaha District, Western Province, Sri Lanka Napagoda MT, Sundarapperuma T, Fonseka D, Amarasiri S, Gunaratna P Scientifica (Cairo) 03-Jun-2018
PMCID:PMC6008615
doi:10.1155/2018/9395052
PMID:29974006
Ethnobotanical study of medicinal plants used against human ailments in Gubalafto District, Northern Ethiopia Chekole G J Ethnobiol Ethnomed 04-Oct-2017
PMCID:PMC5628421
doi:10.1186/s13002-017-0182-7
PMID:28978342
Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence Félix-Silva J, Silva-Junior AA, Zucolotto SM, Fernandes-Pedrosa MD Evid Based Complement Alternat Med 21-Aug-2017
PMCID:PMC5585606
doi:10.1155/2017/5748256
PMID:28904556
Bufadienolides of Kalanchoe species: an overview of chemical structure, biological activity and prospects for pharmacological use Kolodziejczyk-Czepas J, Stochmal A Phytochem Rev 02-Aug-2017
PMCID:PMC5696496
doi:10.1007/s11101-017-9525-1
PMID:29200987

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroid lactones / Bufanolides and derivatives
(3S,5S,8R,9S,10S,13R,14S,17R)-3-[(2S,3S,4S,6S)-3,4-dihydroxy-6-methyloxan-2-yl]oxy-5,14-dihydroxy-13-methyl-12-oxo-17-(6-oxopyran-3-yl)-1,2,3,4,6,7,8,9,11,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde 11994610 Click to see 560.60 unknown https://doi.org/10.1021/OL061873M
[(1R,2R,4R,6R,7R,10S,11R,14S,16S,18R,19S)-2,10,14,16-tetrahydroxy-6-methyl-7-(6-oxopyran-3-yl)-3-oxapentacyclo[9.7.1.01,14.04,19.06,10]nonadecan-18-yl] acetate 21123747 Click to see CC(=O)OC1CC(CC2(C13C4C(CC2)C5(CCC(C5(CC4OC3O)C)C6=COC(=O)C=C6)O)O)O 490.50 unknown https://doi.org/10.1021/OL061873M
[(3S,5S,8R,9S,10S,13R,14S,17R)-10-formyl-14-hydroxy-13-methyl-17-(6-oxopyran-3-yl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-5-yl] acetate 14135794 Click to see 620.70 unknown https://doi.org/10.1021/OL061873M
[10-formyl-14-hydroxy-13-methyl-17-(6-oxopyran-3-yl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-5-yl] acetate 14135793 Click to see 620.70 unknown https://doi.org/10.1021/OL061873M
[2,10,14,16-Tetrahydroxy-6-methyl-7-(6-oxopyran-3-yl)-3-oxapentacyclo[9.7.1.01,14.04,19.06,10]nonadecan-18-yl] acetate 14483909 Click to see 490.50 unknown https://doi.org/10.1002/CHIN.200710204
https://doi.org/10.1021/OL061873M
19-Oxo-3-beta,5,14-trihydroxy-5-beta-bufa-20,22-dienolide-3-acetate 632395 Click to see 458.50 unknown https://doi.org/10.1002/CHIN.200710204
https://doi.org/10.1021/OL061873M
19-Oxo-3-beta,5,14-trihydroxy-5-beta-bufa-20,22-dienolide-3-acetate 19985 Click to see 458.50 unknown https://doi.org/10.1002/CHIN.200710204
3-(3,4-Dihydroxy-6-methyloxan-2-yl)oxy-5,14-dihydroxy-13-methyl-12-oxo-17-(6-oxopyran-3-yl)-1,2,3,4,6,7,8,9,11,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde 73172543 Click to see 560.60 unknown https://doi.org/10.1021/OL061873M
3,5,14-trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde 3659747 Click to see CC12CCC3C(C1(CCC2C4=COC(=O)C=C4)O)CCC5(C3(CCC(C5)O)C=O)O 416.50 unknown https://doi.org/10.1002/CHIN.200710204
https://doi.org/10.1021/OL061873M
5,11-Dihydroxy-9,16-dimethyl-8-(6-oxopyran-3-yl)-15,17,20-trioxahexacyclo[14.3.1.114,18.01,13.04,12.05,9]henicosane-13-carbaldehyde 4482623 Click to see CC12CC(C3C(C1(CCC2C4=COC(=O)C=C4)O)CCC56C3(C7CC(C5)OC(O7)(O6)C)C=O)O 472.50 unknown https://doi.org/10.1021/OL061873M
https://doi.org/10.1002/CHIN.200710204
5,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde 14179407 Click to see 562.60 unknown https://doi.org/10.1021/OL061873M
https://doi.org/10.1002/CHIN.200710204
Bryophyllin A 5488801 Click to see 472.50 unknown https://doi.org/10.1021/OL061873M
CID 5462418 5462418 Click to see CC12CC(C3C(C1(CCC2C4=COC(=O)C=C4)O)CCC56C3(C7CC(C5)OC(O7)(O6)C)C=O)O 472.50 unknown https://doi.org/10.1002/CHIN.200710204
Hellebrigenin 259577 Click to see CC12CCC3C(C1(CCC2C4=COC(=O)C=C4)O)CCC5(C3(CCC(C5)O)C=O)O 416.50 unknown https://doi.org/10.1021/OL061873M
Hellebrigenin 3-acetate 267436 Click to see 458.50 unknown https://doi.org/10.1021/OL061873M
Kalanchoside A 11994608 Click to see 562.60 unknown https://doi.org/10.1021/OL061873M
Kalanchoside B 11994609 Click to see 562.60 unknown https://doi.org/10.1021/OL061873M
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Umbelliferone 5281426 Click to see C1=CC(=CC2=C1C=CC(=O)O2)O 162.14 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Luteolin 5280445 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O 286.24 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol 5280863 Click to see 286.24 unknown https://doi.org/10.1021/NP50065A009
Patuletin 5281678 Click to see 332.26 unknown https://doi.org/10.1016/S0031-9422(00)98096-8
Quercetin 5280343 Click to see 302.23 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
3,5,7-trihydroxy-6-methoxy-2-[4-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]chromen-4-one 163060690 Click to see 462.40 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one 101548886 Click to see 478.40 unknown https://doi.org/10.1016/S0031-9422(00)98096-8
Quercitrin 5280459 Click to see 448.40 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one 163024738 Click to see 608.50 unknown https://doi.org/10.1021/NP50065A009
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 6-O-methylated flavonoids
Nepetin 5317284 Click to see 316.26 unknown https://doi.org/10.1021/NP50065A009

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