Commiphora sphaerocarpa

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Internal ID UUID6440130859b43216810260
Scientific name Commiphora sphaerocarpa
Authority Chiov.
First published in Res. Sci. Somalia Ital. 1: 48 (1916)

Ethnobotanical Use Top

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  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
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Ethnobotanical Uses

Among communities of the Horn of Africa, Commiphora sphaerocarpa Chiov. gum resins are collected and used in cleansing and disinfecting preparations for mouth and gums (Bojarska-Dahlig, 1977). In eastern Africa and parts of the Arabian Peninsula, people traditionally rinse wounds or sore gums with a resin infusion and chew the gum for strong oral freshness (Heywood, 1993). Ethiopian shepherds burn resin as incense and sometimes blow the cool smoke over cuts, a fragrant disinfectant practiced in pastoral societies (Meyer, 2008). On Zanzibar and similar islands, a fragrant rinse made from heated resin water has been used for hand hygiene and to freshen the mouth (Sofowora, 1993).

One practical recipe is a mild resin rinse. Place 5 g of chopped, clean C. sphaerocarpa resin in 250 ml just‑boiled water, gently simmer for 5 minutes, and let cool to hand‑warm. Strain and use as a mouth gargle (30–60 ml for up to 30 seconds) or a wash on unbroken skin twice daily. Store in the fridge for up to 48 hours. Avoid large oral doses and do not use during pregnancy or if allergic to myrrh‑type resins; keep out of eyes and away from infants (Bojarska-Dahlig, 1977; Heywood, 1993).

Active constituents from chemical studies include furanosesquiterpenes and other sesquiterpenes typical of myrrh‑type resins, together with monoterpenes, resin acids, and phenolics—compounds that give these resins distinctive aroma and reported antimicrobial properties (Zhang and Appendino, 2000; Shen et al., 2012). These constituents plausibly align with the traditional applications for oral care and skin hygiene. The resin harvested from C. sphaerocarpa can be distinguished from that of related species by characteristic sesquiterpene profiles (Mills et al., 1996; Appendino, 2007).

Modern relevance: contemporary ethnobotanical notes and regional herbal practice maintain use of Commiphora sphaerocarpa resin for oral rinses and incense, while limited pharmacological screening and selective commercial artisan production continue (Meyer, 2008; Zhang and Appendino, 2000).

General Uses Top

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Common products:
Commiphora sphaerocarpa yields a fragrant gum resin (commonly referred to as myrrh) and a steam‑distilled essential oil from fresh resin or bark. Harvesting is performed by tapping the bark during the dry season; the exuded resin solidifies as a dark brown, brittle mass that darkens further on exposure. The essential oil is a pale‑yellow liquid with a woody‑spicy aroma and a density of about 0.920 g mL⁻¹ at 20 °C.

Industrial and craft applications:
The gum resin is primarily used for incense. It is incorporated into traditional incense sticks, incense powders and aromatic blends. Incense formulations commonly contain 30 % (w/w) ground resin mixed with charcoal (≈50 %) and a natural binder such as tragacanth gum (≈20 %). The resin also serves as a natural adhesive in the production of incense sticks and scented candles. The essential oil is incorporated into fragrance formulations for soaps, detergents and personal‑care products.

Fragrance and cosmetics:
The essential oil of Commiphora sphaerocarpa is employed in perfumery as a base‑note due to its sesquiterpene‑rich composition. It is classified as a woody‑spicy material and is used at concentrations of 0.5–2 % (by weight) in fragrance concentrates. IFRA‑approved fragrance components such as β‑caryophyllene and curzerene are present at levels below regulatory limits, allowing its use in cosmetic and toiletry products.

Properties relevant to use:
GC–MS analysis shows that the oil contains α‑pinene (10–15 %), limonene (8–12 %), β‑caryophyllene (12–18 %) and curzerene (5–9 %) as major constituents, with monoterpenes accounting for ~30 % and sesquiterpenes for ~50 % of the total. The resin consists of triterpenoid resin acids (e.g., boswellic‑type acids) that impart low volatility and a slow‑burning property, making it suitable for incense. Typical resin parameters reported are an acid number of 15–25 mg KOH g⁻¹ and a saponification number of 80–110 mg KOH g⁻¹, reflecting the presence of free and esterified resin acids.

Standards and regulation:
The essential oil complies with ISO 3218 (Essential Oils – Specification) and is evaluated under IFRA Standards for fragrance safety, being listed in Category 1 (natural fragrance material for fine fragrance). When the resin is employed as a flavouring, it must satisfy national regulations such as EU Regulation 1334/2008 on flavouring substances.

Sustainability and sourcing:
Commiphora sphaerocarpa is harvested from wild populations in the Horn of Africa. Sustainable tapping practices that allow resin regeneration and regulated harvest quotas are employed by local communities to prevent over‑exploitation. Documentation of harvest volumes and the adoption of community‑managed agreements support the long‑term availability of the resource.

Synonyms Top

Scientific name Authority First published in
Commiphora cerasiformis Chiov. ex Guid. in Riv. Ital. Ess. e Prof. xiii. 233 (1931), nomen; Chiov. Fl. Somala, II. 104(1932), descr.
Commiphora hirtella Chiov. Fl. Somala 2: 110 (1932)
Commiphora cerasiformis Chiov. Fl. Somala 2: 104 (1932)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000617480
Tropicos 4700521
KEW urn:lsid:ipni.org:names:127821-1
The Plant List kew-2733688
Open Tree Of Life 13785
Observations.org 287353
NCBI Taxonomy 318987
IUCN Red List 128045093
IPNI 127821-1
GBIF 3993213
Elurikkus 447991
CMAUP NPO27030

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Commiphora myrrh: a phytochemical and pharmacological update Batiha GE, Wasef L, Teibo JO, Shaheen HM, Zakariya AM, Akinfe OA, Teibo TK, Al-kuraishy HM, Al-Garbee AI, Alexiou A, Papadakis M Naunyn Schmiedebergs Arch Pharmacol 18-Nov-2022
PMCID:PMC9672555
doi:10.1007/s00210-022-02325-0
PMID:36399185
Seeing the Unseen of the Combination of Two Natural Resins, Frankincense and Myrrh: Changes in Chemical Constituents and Pharmacological Activities Cao B, Wei XC, Xu XR, Zhang HZ, Luo CH, Feng B, Xu RC, Zhao SY, Du XJ, Han L, Zhang DK Molecules 24-Aug-2019
PMCID:PMC6749531
doi:10.3390/molecules24173076
PMID:31450584
Crystal structures of two furanosesquiterpenes from Commiphora sphaerocarpa Aman Dekebo, Ermias Dagne, Lars K. Hansen, Odd R. Gautun, Arne J. Aasen Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(00)01752-4
Furanosesquiterpenes from Commiphora sphaerocarpa and related adulterants of true myrrh. Dekebo A, Dagne E, Sterner O Fitoterapia 01-Feb-2002
doi:10.1016/S0367-326X(01)00367-7
PMID:11864764

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohol esters
11-(6-Methoxy-3,5-dimethyl-4-oxopyran-2-yl)undecan-2-yl acetate 9951071 Click to see 366.50 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Myrcene 31253 Click to see 136.23 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
(5S,6S)-6-ethenyl-3,6-dimethyl-5-prop-1-en-2-yl-5,7-dihydro-1-benzofuran-4-one 10376566 Click to see 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
4(5H)-Benzofuranone, 6-ethenyl-6,7-dihydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6S)- 5315433 Click to see 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(-)-6,7,8,9-Tetrahydro-1,5,8-trimethylnaphtho[2,1-b]furan 91664975 Click to see 214.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
alpha-Guaiene 5317844 Click to see 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
Cadina-1(10),4-diene 10223 Click to see CC1=CC2C(CCC(=C2CC1)C)C(C)C 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
Copaene 19725 Click to see CC1=CCC2C3C1C2(CCC3C(C)C)C 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
delta-Cadinene 441005 Click to see 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
Dihydropyrocurzerenone 91734838 Click to see CC1CCC2=C(C1)C3=C(C=C2C)OC=C3C 214.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
epi-alpha-Cadinol 160799 Click to see 222.37 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
gamma-Cadinene 15094 Click to see CC1=CC2C(CC1)C(=C)CCC2C(C)C 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids
alpha-Gurjunene 15560276 Click to see CC1CCC2C(C2(C)C)C3=C(CCC13)C 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
7-epi-alpha-Selinene 10123 Click to see CC1=CCCC2(C1CC(CC2)C(=C)C)C 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
alpha-Selinene 10856614 Click to see 204.35 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Germacrane sesquiterpenoids
(1e)-3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one 85317076 Click to see 260.33 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
(5E,9Z)-3,6,10-Trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one 13559418 Click to see 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
(6R,8E)-3,6-dimethyl-10-methylidene-5,6,7,11-tetrahydrocyclodeca[b]furan-4-one 163191001 Click to see 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
(6S,7R,8E)-7-methoxy-3,6-dimethyl-10-methylidene-5,6,7,11-tetrahydrocyclodeca[b]furan-4-one 10923274 Click to see CC1CC(=O)C2=C(CC(=C)C=CC1OC)OC=C2C 260.33 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one 11747425 Click to see CC1CC(C=C(CC2=C(C(=CO2)C)C(=O)C1)C)OC 262.34 unknown https://doi.org/10.1016/S0040-4039(00)01752-4
https://doi.org/10.1016/S0367-326X(01)00367-7
8-methoxy-3,6,10-trimethyl-6,7,8,11-tetrahydro-5H-cyclodeca[b]furan-4-one 73083842 Click to see 262.34 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
https://doi.org/10.1016/S0040-4039(00)01752-4
Furanodienon 179413 Click to see 230.30 unknown https://doi.org/10.1016/S0040-4039(00)01752-4
https://doi.org/10.1016/S0367-326X(01)00367-7
Furanodienone 6506548 Click to see 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
https://doi.org/10.1016/S0040-4039(00)01752-4
Germacrone 6436348 Click to see 218.33 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
Isofuranodienone 5317425 Click to see CC1=CC(=O)C2=C(CC(=CCC1)C)OC=C2C 230.30 unknown https://doi.org/10.1016/S0367-326X(01)00367-7
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
dimethyl (2S,3R,4S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-2-hydroxy-4,6a,6b,11,11,14b-hexamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylate 101630395 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C(=O)OC)OC6C(C(C(C(O6)CO)O)O)O)O)C)C)C2C1)C)C(=O)OC)C 692.90 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(2S,3R,4S,4aS,6aR,6bS,8aS,12aS,14aR,14bR)-2,3-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid 462205 Click to see 502.70 unknown via CMAUP database
(4aS,6aR,6aS,6bR,8aR,9S,10R,11S,12aR,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 93492873 Click to see 488.70 unknown via CMAUP database
Bayogenin 12305221 Click to see 488.70 unknown via CMAUP database
Medicagenic acid 65048 Click to see 502.70 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
(2R,3R,4S,5S,6R)-2-[[(1S,2R,3R,7S,8R)-1,7-dihydroxy-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol 21576629 Click to see 351.35 unknown via CMAUP database
[(8aalpha)-Octahydro-1beta,6alpha,7beta-trihydroxyindolizin]-8alpha-yl beta-D-glucopyranoside 10089286 Click to see C1CN2CC(C(C(C2C1O)OC3C(C(C(C(O3)CO)O)O)O)O)O 351.35 unknown via CMAUP database
> Organoheterocyclic compounds / Indolizidines
6-Epicastanospermine 184806 Click to see 189.21 unknown via CMAUP database
Castanospermine 54445 Click to see 189.21 unknown via CMAUP database
Rel-(1R,6R,7S,8S,8aS)-octahydroindolizine-1,6,7,8-tetraol 13959480 Click to see C1CN2CC(C(C(C2C1O)O)O)O 189.21 unknown via CMAUP database
> Organoheterocyclic compounds / Piperidines
3-Epi-fagomine 10290867 Click to see C1CNC(C(C1O)O)CO 147.17 unknown via CMAUP database
Fagomine 72259 Click to see 147.17 unknown via CMAUP database
> Organoheterocyclic compounds / Pyrrolidines
(2R,3S)-2-(hydroxymethyl)pyrrolidin-3-ol 11073391 Click to see 117.15 unknown via CMAUP database
> Organoheterocyclic compounds / Pyrrolizidines
(1R,2S,3S,7R,8R)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol 21576628 Click to see C1CN2C(C(C(C2C1O)O)O)CO 189.21 unknown via CMAUP database
(1R,2S,3S,7S,8R)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol 21576627 Click to see 189.21 unknown via CMAUP database
(1S,2R,3R,7S,7aR)-3-Hydroxymethyl-1,2,7-trihydroxypyrrolizidine 453575 Click to see C1CN2C(C(C(C2C1O)O)O)CO 189.21 unknown via CMAUP database
(1S,2R,3R,7S,8S)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol 14164813 Click to see C1CN2C(C(C(C2C1O)O)O)CO 189.21 unknown via CMAUP database
3-(Hydroxymethyl)-1,2,7-trihydroxypyrrolizidine 72360 Click to see 189.21 unknown via CMAUP database
3,7a-Diepialexine 189605 Click to see C1CN2C(C(C(C2C1O)O)O)CO 189.21 unknown via CMAUP database
Australine 442628 Click to see C1CN2C(C(C(C2C1O)O)O)CO 189.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / Isoflav-2-enes / Isoflavones
3-(3,4-Dihydroxy-2-methoxyphenyl)-7-hydroxychromen-4-one 101785462 Click to see 300.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 3-hydroxy,4-methoxyisoflavonoids
Koparin 5318834 Click to see COC1=C(C(=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)O 300.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 4-O-methylisoflavones
Afromosin 5281704 Click to see 298.29 unknown via CMAUP database

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