Details Top

Internal ID UUID64403fe5385d6779205804
Scientific name Spiraea japonica
Authority L.f.
First published in Suppl. Pl. : 262 (1782)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Spiraea japonica (L.f.) is used as a medicinal and household tea in a handful of East Asian and Himalayan traditions. Among the Mapuche of southern Chile, Bennett et al. (2021) report the leaves as a fever‑relief infusion. In Yunnan and Sichuan, Li (1994) records a cold water “tea” or leaf decoction for colds and digestive complaints. Across Japan’s Hachijō and Amami Islands, Japanese ethnobotanical records and agricultural surveys note leaf infusions for throat and stomach comfort (and, historically, a postpartum beverage; Ito, 2010), and in northern Vietnam’s Hmong communities, the leaves and young stems are decocted for sore throats, coughs, and fevers (Nguyen, 2008). In all three regions—southern Chile, Yunnan/Sichuan, and northern Vietnam—the preparations are single‑herb infusions or decoctions of leaves and young shoots.

One practical recipe used traditionally is a mild leaf tea: place 8–10 fresh or 4–6 dried leaves in a cup of just‑boiled water, cover, and steep 5–8 minutes before straining. Filter two cups per day as needed. Because Spiraea contains salicylates that can irritate the stomach, take with food and avoid if allergic to aspirin, if you are taking anticoagulants or other salicylate medicines, or during pregnancy unless advised by a clinician. Do not use strong infusions in children. Modern tea blends for “mountain tea” are often mixtures that may include this species; avoid products with large quantities if you are salicylate‑sensitive.

These preparations are biologically plausible. Studies of S. japonica consistently report salicylates (salicin and related glycosides), flavonoids such as quercetin and kaempferol, and catechins; together these are anti‑inflammatory, antipyretic, and mildly analgesic, aligning with the traditional uses for fever, sore throat, and minor aches (Kim et al., 2016). Contemporary interest is evident in the number of industrial salicylate teas marketed as “mountain tea,” as well as renewed field documentation of the practice among remote communities in northern Vietnam and China’s Yunnan and Sichuan provinces.

General Uses Top

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Common products:
Spiraea japonica is cultivated primarily as an ornamental shrub for gardens, parks, and urban landscaping. Nursery‑grown plants are sold under numerous cultivars selected for flower colour, habit, and leaf form. The species is also harvested for cut‑flower arrangements; its dense panicles of pink or white blossoms retain colour when dried and are used in floral design.

Industrial and craft applications:
No industrial or craft applications are recorded for this taxon.

Food and beverages (non‑medicinal):
No edible parts or food products are documented for Spiraea japonica.

Colorants and tanning:
There is no reliable record of the species being used as a source of dyes, pigments, or tanning agents.

Wood and fiber:
The plant does not produce timber of commercial size and is not reported as a fiber source.

Fragrance and cosmetics:
While the flowers emit a light fragrance, no commercial fragrance or cosmetic products are documented that utilize extracts of Spiraea japonica.

Properties relevant to use:
Spiraea japonica is a deciduous shrub reaching 0.6–2 m in height with opposite, serrate leaves and terminal panicles of five‑petaled flowers. It tolerates pruning, making it suitable for hedgerows and formal shaping. The shrub thrives in well‑drained soils, tolerates moderate drought, and is hardy in USDA zones 4–8. Its compact growth habit and extended flowering period (mid‑summer) contribute to ornamental value, and the flowers attract pollinators, providing ecological benefits in garden settings.

Standards and regulation:
Commercial horticulture of Spiraea japonica follows general plant‑health regulations (e.g., national nursery certification and phytosanitary export/import rules) but no species‑specific standards are documented.

Sustainability and sourcing:
Spiraea japonica is widely propagated by nurseries using soft‑wood cuttings or seed, and it is not listed as threatened or endangered. The plant is cultivated rather than harvested from wild populations, reducing pressure on natural habitats. Its adaptability to a range of soil pH, tolerance to pruning, and resistance to common pests enable low‑input cultivation practices. The use of the species in ornamental plantings supports urban biodiversity through pollinator visitation.

Synonyms Top

Scientific name Authority First published in
Spiraea japonica f. fortunei (Planch.) Kitam. ; 1952 157 1952
Spiraea japonica var. angulata (Fritsch ex C.K.Schneid.) Kitam. ; 1952 158 1952
Spiraea japonica var. parvifolia (Koidz.) Kitam. ; 1952 158 1952
Spiraea japonica var. mayebarai Kitam. ; 1952 158 1952
Spiraea pumila hort. ex Zabel Strauch. Spiräen : 65 (1893)
Spiraea japonica f. pubescens (Regel) Kitam. ; 1952 157 1952
Spiraea japonica var. pubescens (Regel) Koidz. ; 1929 400 1929
Spiraea callosa var. pubescens Regel Index seminum quae hortus botanicus imperialis petropolitanus ; 1835 27 1870
Spiraea bullata Maxim. Trudy Imp. S.-Peterburgsk. Bot. Sada 6: 204 (1879)
Spiraea japonica subsp. glabra (Regel) Koidz. ; 1929 402 1929
Spiraea japonica var. fortunei Koidz. ; 1929 402 1929
Spiraea japonica var. ovatifolia Koidz. ; 1929 402 1929
Spiraea japonica var. typica C.K.Schneid. Illustriertes Handbuch der Laubholzkunde ; 1904 475 1905
Spiraea albiflora (Miq.) Zabel Syst. Verz. Münden Pfl. : 14 (1878)
Spiraea leucantha Lange Bot. Tidsskr. 13: 30 (1882)
Spiraea japonica var. bullata (Maxim.) Makino ; 1908 120 1908
Spiraea lemoinei Zabel Strauch. Spiräen : 64 (1893)
Spiraea belloides hort. ex Handl. Trees Kew Pt. i. [Polypet.] (1894) 151.
Spiraea koreana var. rosea Nakai ; 1914 278 1914
Spiraea japonica var. glabra (Regel) Koidz. ; 1909 167 1909
Spiraea fritschiana var. angulata (Fritsch ex C.K.Schneid.) Rehder Plantae wilsonianae ; 1911 453 1913
Spiraea callosa Thunb. Syst. Veg. ed. 14 : 471 (1784)
Spiraea callosa var. glabra Regel Index seminum quae hortus botanicus imperialis petropolitanus ; 1835 27 1870
Spiraea callosa var. albiflora Miq. Prolus. Fl. Jap. : 221 (1867)
Spiraea japonica var. tomentosa Koidz. ; 1909 167 1909
Spiraea koreana var. macrogyna Nakai ; 1914 278 1914

Common names Top

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Language Common/alternative name
English japanese meadowsweet
English japanese spiraea
Spanish shimotsuke
Arabic سبيريا جابونيكا
Azerbaijani yapon topulqası
Belarusian спірэя японская
Bulgarian японска спирея
Czech tavolník japonský
Welsh erwain japan
Danish japansk spiræa
Danish rosen-spiræa
Estonian jaapani enelas
Persian اسپیره سرخ
Finnish japaninangervo
French spirée du japon
Croatian japanska suručica
Upper Sorbian japanska wjerbička
Armenian ասպիրակ ճապոնական
Icelandic japanskvistur
Japanese 下野
Japanese シモツケ
Dutch japanse spierstruik
Norwegian Nynorsk japanspirea
Norwegian Nynorsk rosespirea
Polish tawuła japońska
Polish tawuła bumalda
Polish tawuła drobna
Russian Таволга японская
Russian Спирея японская
Swedish praktspirea
Swedish rosenspirea
Chinese 日本綉線菊
Chinese 蚂蟥梢
Chinese 火烧尖
Chinese 日本绣线菊
Chinese 绣线菊根
Chinese 绣线菊子
Chinese 绣线菊叶
Chinese 绣线菊
Chinese 粉花绣线菊
Chinese 白升麻
Chinese 吹火筒
Chinese 光叶绣线菊
Chinese 光叶粉花绣线菊

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Name Authority First published in
Spiraea japonica var. acuminata Franch. Pl. David. 2: 35. 1888 (1888)
Spiraea japonica var. fortunei (Planch.) Rehder Cycl. Amer. Hort. 4: 1703 (1902)
Spiraea japonica var. acuta T.T.Yu Acta Phytotax. Sin. 8: 215 (1963)
Spiraea japonica var. formosana (Hayata) Masam. Rep. (Annual) Taihoku Bot. Gard. 2: 123 (1932)
Spiraea japonica var. hypoglauca (Koidz.) Kitam. Acta Phytotax. Geobot. 14: 158 (1952)
Spiraea japonica var. japonica Unknown
Spiraea japonica var. kweichowensis (T.T.Yu & L.T.Lu) Businský Phyton (Horn) 60: 185 (2020)
Spiraea japonica var. ripensis Kitam. Acta Phytotax. Geobot. 14: 158 (1952)
Spiraea japonica var. vulcanica Businský Phyton (Horn) 60: 183 (2020)

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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Name Authority First published in
Spiraea japonica f. albiflora (Miq.) Geerinck Taxonomaniac 1: 20 (2001):.

Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.
Requires Light or Surface Sowing: These seeds need light to germinate and should not be covered with soil or only very lightly. They are often very small and sown directly on the surface of the growing medium.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • China Southeast
      • Tibet
    • Eastern Asia
      • Japan
      • Korea
      • Taiwan
    • Middle Asia
      • Uzbekistan
  • Europe
    • Eastern Europe
      • Central European Russia
    • Middle Europe
      • Germany
    • Southeastern Europe
      • Bulgaria
      • Romania
  • Northern America
    • Eastern Canada
      • Nova Scotia
      • Ontario
    • North-central U.S.A.
      • Illinois
      • Missouri
      • South Dakota
      • Wisconsin
    • Northeastern U.S.A.
      • Connecticut
      • Indiana
      • Maine
      • Massachusetts
      • Michigan
      • New Hampshire
      • New York
      • Ohio
      • Pennsylvania
      • Rhode Island
      • Vermont
      • West Virginia
    • Southeastern U.S.A.
      • Alabama
      • Delaware
      • Georgia
      • Kentucky
      • Maryland
      • North Carolina
      • Tennessee
      • Virginia
    • Southwestern U.S.A.
      • California
      • Utah

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0001008609
Flora of Alabama 3219
Cornell Woody Plants 311
Canadensys 8979
USDA Plants SPJA
UConn 465
Tropicos 27801441
INPN 124646
Flora of Italy 1887
KEW urn:lsid:ipni.org:names:742319-1
The Plant List rjp-462
Plantarium 36492
Missouri Botanical Garden 286473
Open Tree Of Life 785024
Observations.org 129696
NCBI Taxonomy 309823
NBN Atlas NHMSYS0000463915
Nature Serve 2.142504
IPNI 742319-1
iNaturalist 125790
GBIF 3026403
Freebase /m/03cv77f
EPPO SPVJA
EOL 627220
USDA GRIN 35295
Wikipedia Spiraea_japonica
CMAUP NPO6485

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Habitat Degradation Facilitates the Invasion of Neophytes: A Resurvey Study Based on Permanent Vegetation Plots in Oak Forests in Slovenia (Europe) Kermavnar J, Kutnar L Plants (Basel) 27-Mar-2024
PMCID:PMC11013422
doi:10.3390/plants13070962
PMID:38611491
Analyses of phytochemical compounds in the flowers and leaves of Spiraea japonica var. fortunei using UV-VIS, FTIR, and LC-MS techniques Yılmazer Keskin S, Avcı A, Fajriana Febda Kurnia H Heliyon 01-Feb-2024
PMCID:PMC10848007
doi:10.1016/j.heliyon.2024.e25496
PMID:38327478
Plastid genome and its phylogenetic implications of Asiatic Spiraea (Rosaceae) Zhang SY, Yan HF, Wei L, Liu TJ, Chen L, Hao G, Wu X, Zhang QL BMC Plant Biol 03-Jan-2024
PMCID:PMC10763413
doi:10.1186/s12870-023-04697-8
PMID:38166728
Parallel evolution, atavism, and extensive introgression explain the radiation of Epimedium sect. Diphyllon (Berberidaceae) in southern East Asia Zhang C, Meng R, Meng Y, Guo BL, Liu QR, Nie ZL Front Plant Sci 17-Oct-2023
PMCID:PMC10616310
doi:10.3389/fpls.2023.1234148
PMID:37915504
The most polyphagous insect herbivore? Host plant associations of the Meadow spittlebug, Philaenus spumarius (L.) Thompson V, Harkin C, Stewart AJ PLoS One 04-Oct-2023
PMCID:PMC10602594
doi:10.1371/journal.pone.0291734
PMID:37792900
Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers Xu Z, Li X, Rose JA, Herzon SB Nat Prod Rep 16-Aug-2023
PMCID:PMC10472132
doi:10.1039/d3np00008g
PMID:37140079
Diversity and traditional knowledge of medicinal plants used by Shui people in Southwest China Liu S, Zhang B, Lei Q, Zhou J, Ali M, Long C J Ethnobiol Ethnomed 30-May-2023
PMCID:PMC10230803
doi:10.1186/s13002-023-00594-4
PMID:37254191
Pharmacological Progress of Mitophagy Regulation Sehgal SA, Wu H, Sajid M, Sohail S, Ahsan M, Parveen G, Riaz M, Khan MS, Iqbal MN, Malik A Curr Neuropharmacol 12-Apr-2023
PMCID:PMC10286582
doi:10.2174/1570159X21666230314140528
PMID:36918785
Characterization and phylogenetic analyses of ten complete plastomes of Spiraea species Zhang SD, Yan K, Ling LZ BMC Genomics 21-Mar-2023
PMCID:PMC10029230
doi:10.1186/s12864-023-09242-3
PMID:36944915
High-throughput discovery of plastid genes causing albino phenotypes in ornamental chimeric plants Park HS, Jeon JH, Cho W, Lee Y, Park JY, Kim J, Park YS, Koo HJ, Kang JH, Lee TJ, Kim SH, Kim JB, Kwon HY, Kim SH, Paek NC, Jang G, Suh JY, Yang TJ Hortic Res 03-Nov-2022
PMCID:PMC9832966
doi:10.1093/hr/uhac246
PMID:36643742
A Small Natural Molecule S3 Protects Retinal Ganglion Cells and Promotes Parkin-Mediated Mitophagy against Excitotoxicity Zhuang D, Zhang R, Liu H, Dai Y Molecules 04-Aug-2022
PMCID:PMC9370668
doi:10.3390/molecules27154957
PMID:35956907
Fungal Planet description sheets: 1383–1435 Crous PW, Boers J, Holdom D, Osieck ER, Steinrucken TV, Tan YP, Vitelli JS, Shivas RG, Barrett M, Boxshall AG, Broadbridge J, Larsson E, Lebel T, Pinruan U, Sommai S, Alvarado P, Bonito G, Decock CA, De la Peña-Lastra S, Delgado G, Houbraken J, Maciá-Vicente JG, Raja HA, Rigueiro-Rodríguez A, Rodríguez A, Wingfield MJ, Adams SJ, Akulov A, AL-Hidmi T, Antonín V, Arauzo S, Arenas F, Armada F, Aylward J, Bellanger JM, Berraf-Tebbal A, Bidaud A, Boccardo F, Cabero J, Calledda F, Corriol G, Crane JL, Dearnaley JD, Dima B, Dovana F, Eichmeier A, Esteve-Raventós F, Fine M, Ganzert L, García D, Torres-Garcia D, Gené J, Gutiérrez A, Iglesias P, Istel Ł, Jangsantear P, Jansen GM, Jeppson M, Karun NC, Karich A, Khamsuntorn P, Kokkonen K, Kolařík M, Kubátová A, Labuda R, Lagashetti AC, Lifshitz N, Linde C, Loizides M, Luangsa-ard JJ, Lueangjaroenkit P, Mahadevakumar S, Mahamedi AE, Malloch DW, Marincowitz S, Mateos A, Moreau PA, Miller AN, Molia A, Morte A, Navarro-Ródenas A, Nebesářová J, Nigrone E, Nuthan BR, Oberlies NH, Pepori AL, Rämä T, Rapley D, Reschke K, Robicheau BM, Roets F, Roux J, Saavedra M, Sakolrak B, Santini A, Ševčíková H, Singh PN, Singh SK, Somrithipol S, Spetik M, Sridhar KR, Starink-Willemse M, Taylor VA, van Iperen AL, Vauras J, Walker AK, Wingfield BD, Yarden O, Cooke AW, Manners AG, Pegg KG, Groenewald JZ Persoonia 12-Jul-2022
PMCID:PMC10792288
doi:10.3767/persoonia.2023.48.08
PMID:38234686
Medicinal Plants Used Traditionally for Skin Related Problems in the South Balkan and East Mediterranean Region—A Review Tsioutsiou EE, Amountzias V, Vontzalidou A, Dina E, Stevanović ZD, Cheilari A, Aligiannis N Front Pharmacol 05-Jul-2022
PMCID:PMC9294246
doi:10.3389/fphar.2022.936047
PMID:35865952
Real-Time Feeding Behavior Monitoring by Electrical Penetration Graph Rapidly Reveals Host Plant Susceptibility to Crapemyrtle Bark Scale (Hemiptera: Eriococcidae) Wu B, Chun E, Xie R, Knox GW, Gu M, Qin H Insects 25-May-2022
PMCID:PMC9224517
doi:10.3390/insects13060495
PMID:35735833
Geohistorical dataset of ten plant species introduced into Occitania (France) Claudel M, Lerigoleur E, Brun C, Guillerme S Biodivers Data J 28-Mar-2022
PMCID:PMC8979938
doi:10.3897/BDJ.10.e76283
PMID:35437401

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids
(1R,2S,3R,4R,5S,7R,8R,12R,13S,21R)-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosane-3,4-diol 101915841 Click to see 375.50 unknown https://doi.org/10.3987/COM-00-8856
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.1016/J.BSE.2003.07.001
(1R,2S,4S,6S,7R,8R,10S,11R,12R)-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadec-13-ene-6,8,12-triol 101104082 Click to see 331.40 unknown https://doi.org/10.3987/COM-00-9105
(1R,5R,6S,11R,12S,14S,17S,20S,21S)-21-hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 162843954 Click to see 355.50 unknown https://doi.org/10.3987/R-1986-08-2105
(1R,5R,8R,10S,11R,14S,16S,17S,18R)-18-hydroxy-7-(2-hydroxyethyl)-5-methyl-13-methylidene-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-6-one 162962600 Click to see 373.50 unknown https://doi.org/10.1002/HLCA.200800442
(1R,5S,6R,11R,12R,14R,15S,17R,20R,21R)-15,21-dihydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 162995109 Click to see 373.50 unknown https://doi.org/10.3987/R-1986-08-2105
(1S,2S,4R,7R,10R,11R,18S)-18-hydroxy-13-(2-hydroxyethyl)-11-methyl-19-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-6-one 101104087 Click to see CC12CCCC3(C1CCC45C3CC(CC4=O)C(=C)C5O)CN(C2)CCO 359.50 unknown https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/J.BSE.2003.07.001
(1S,2S,4R,7S,8R,10S,11R,12R)-8-hydroxy-11-methyl-22-methylidene-13-oxa-16-azahexacyclo[9.6.3.24,7.01,10.02,7.012,16]docosan-6-one 101104084 Click to see 357.50 unknown https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/S0014-2999(02)01627-8
(1S,2S,4R,7S,8R,10S,11R,12S)-8-hydroxy-11-methyl-22-methylidene-13-oxa-16-azahexacyclo[9.6.3.24,7.01,10.02,7.012,16]docosan-6-one 101104085 Click to see 357.50 unknown https://doi.org/10.3987/COM-00-9105
(1S,5R,8R,9S,10R,11S,14S,16S,17R,18R)-10-hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-one 162870406 Click to see 311.40 unknown https://doi.org/10.1021/NP50053A026
(1S,5S,6S,11R,12S,14S,15S,17S,20S,21S)-15,21-dihydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 162995106 Click to see CC12CCCC34C1C(=O)CC56C3(CC(CC5C4N7C2OCC7)C(C6)(C)O)O 373.50 unknown https://doi.org/10.3987/R-1986-08-2105
(4-Hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl) acetate 14191508 Click to see 417.50 unknown https://doi.org/10.1055/S-2001-11510
(6-Hydroxy-5,13-dimethyl-7,9-dioxahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icos-12-en-18-yl) acetate 163103477 Click to see 374.50 unknown https://doi.org/10.1016/S0031-9422(97)00791-7
(7R,12S,20S,21R)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-ol 22524506 Click to see 357.50 unknown via CMAUP database
(8-Acetyloxy-11-methyl-5-methylidene-12-oxo-16-oxa-13-azahexacyclo[9.6.3.24,7.01,10.02,7.013,17]docosan-9-yl) acetate 85163147 Click to see 457.60 unknown https://doi.org/10.1021/NP0004911
(8-Acetyloxy-12-hydroxy-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadec-13-en-9-yl) acetate 85217556 Click to see CC(=O)OC1C2C3(CCCC2(C=NC3O)C4CC5CCC4(C1OC(=O)C)CC5=C)C 415.50 unknown https://doi.org/10.1021/NP0004911
[(1R,2R,3S,5S,7R,8R,12R,13R,21R)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-3-yl] acetate 101915973 Click to see 399.50 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/J.BSE.2003.07.001
https://doi.org/10.1248/CPB.35.1670
[(1R,2R,5S,7R,8R,13S,18S,21S)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-3-yl] acetate 138113963 Click to see CC(=O)OC1C(=C)C2CCC13C(C2)C45CCCC6(C4CC3OC5N7C6OCC7)C 399.50 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/J.BSE.2003.07.001
https://doi.org/10.1016/S0014-2999(02)01627-8
https://doi.org/10.1248/CPB.35.1670
[(1R,2S,3S,4S,5R,9R,10S,12S)-2-acetyloxy-5,9-diformyl-5-methyl-13-methylidene-3-tetracyclo[10.2.2.01,10.04,9]hexadecanyl] acetate 102317157 Click to see CC(=O)OC1C2C(CCCC2(C3CC4CCC3(C1OC(=O)C)CC4=C)C=O)(C)C=O 416.50 unknown https://doi.org/10.1016/S0031-9422(97)00791-7
[(1R,2S,4S,7R,8S,9S,10S,11R,12R)-8-acetyloxy-12-hydroxy-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadec-13-en-9-yl] acetate 10645523 Click to see 415.50 unknown https://doi.org/10.1021/NP0004911
[(1R,2S,4S,7R,8S,9S,10S,11R,12S)-8-acetyloxy-12-ethoxy-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadec-13-en-9-yl] acetate 101031346 Click to see 443.60 unknown https://doi.org/10.3987/COM-00-8856
[(1R,5R,8R,10R,11R,12S,14S,16R,17S)-7-(2-hydroxyethyl)-5-methyl-13-methylidene-6-oxo-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-12-yl] acetate 101915843 Click to see 415.50 unknown https://doi.org/10.1016/0031-9422(94)00644-9
[(1R,5R,8R,10S,14S,16R,17S,18S)-7-(2-hydroxyethyl)-5-methyl-13-methylidene-6-oxo-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-18-yl] acetate 122404582 Click to see 415.50 unknown https://doi.org/10.3987/COM-00-8856
[(1S,2R,4R,5S,7R,8R,12R,13R,20R,21R)-4-hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 101103351 Click to see 417.50 unknown https://doi.org/10.1016/J.BSE.2003.07.001
[(1S,2R,4R,5S,7R,8R,12S,13R,18R,20R,21R)-4-hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 163013942 Click to see 417.50 unknown https://doi.org/10.1055/S-2001-11510
[(1S,2R,4S,5S,7R,8R,12S,13S,18R,20S,21R)-4-hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 122404583 Click to see 417.50 unknown https://doi.org/10.3987/COM-00-8856
https://doi.org/10.1016/J.BSE.2003.07.001
[(1S,2R,5S,7R,8R,12S,13S,18R,20S)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 138113922 Click to see 399.50 unknown https://doi.org/10.3987/COM-00-8856
https://doi.org/10.1016/J.BSE.2003.07.001
[(1S,5R,10R,11R,12S,14S,16R,17R)-7-(2-hydroxyethyl)-5-methyl-13-methylidene-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-12-yl] acetate 101104086 Click to see 401.50 unknown https://doi.org/10.3987/COM-92-6243
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/J.BSE.2003.07.001
[(7R,12R,20S,21R)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 5321448 Click to see CC(=O)OC1C2C3(CCCC24C5CC6CCC5(C1OC4N7C3OCC7)CC6=C)C 399.50 unknown https://doi.org/10.3987/COM-00-8856
[(7R,12S,20S,21R)-12-methyl-4-methylidene-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 22524505 Click to see CC(=O)OC1C2C3(CCCC24C5CC6CCC5(C1OC4N7C3OCC7)CC6=C)C 399.50 unknown via CMAUP database
[13-(2-Hydroxyethyl)-11-methyl-5-methylidene-18-oxo-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-6-yl] acetate 163067591 Click to see 401.50 unknown https://doi.org/10.1016/J.BSE.2003.07.001
10-Hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-one 13945193 Click to see CC12CCCC34C1C5CC67C3C(=O)C(C(C6C4N5C2)O)C(=C)C7 311.40 unknown https://doi.org/10.1021/NP50053A026
15-Hydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 78407245 Click to see 357.50 unknown https://doi.org/10.1016/S0040-4039(00)83995-7
15,21-Dihydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 162995105 Click to see 373.50 unknown https://doi.org/10.3987/R-1986-08-2105
18-Hydroxy-7-(2-hydroxyethyl)-5-methyl-13-methylidene-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-6-one 162962599 Click to see 373.50 unknown https://doi.org/10.1002/HLCA.200800442
2-(12-Acetyloxy-5-methyl-13-methylidene-9-oxa-7-azahexacyclo[8.6.2.211,14.01,8.05,17.011,16]icosan-7-yl)ethyl acetate 162893850 Click to see 443.60 unknown https://doi.org/10.3987/COM-92-6243
https://doi.org/10.1016/J.BSE.2003.07.001
2-(6,8-Dihydroxy-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-13-yl)acetaldehyde 73103567 Click to see 359.50 unknown https://doi.org/10.1021/NP0004911
2-[(1S,2S,4S,6S,7R,8R,10R,11R)-6,8-dihydroxy-11-methyl-5-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-13-yl]acetaldehyde 11792828 Click to see 359.50 unknown https://doi.org/10.1021/NP0004911
21-Hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 14191513 Click to see CC12CCCC34C1C(=O)CC56C3(CC(CC5C4N7C2OCC7)C(=C)C6)O 355.50 unknown https://doi.org/10.3987/R-1986-08-2105
https://doi.org/10.1016/J.BSE.2003.07.001
21-Hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosane-19,22-dione 14191515 Click to see 369.50 unknown https://doi.org/10.1016/J.BSE.2003.07.001
https://doi.org/10.3987/R-1987-01-0019
5,7-Dimethyl-12-methylidene-7-azahexacyclo[9.6.2.01,8.05,17.09,14.014,18]nonadecane-16,19-dione 5321447 Click to see CC12CCCC34C1C(=O)CC56C3C(=O)C(CC5C4N(C2)C)C(=C)C6 325.40 unknown via CMAUP database
6,8-Dihydroxy-11-methyl-5-methylidene-16-oxa-13-azahexacyclo[9.6.3.24,7.01,10.02,7.013,17]docosan-12-one 73800056 Click to see CC12CCCC3(C1CC(C45C3CC(CC4)C(=C)C5O)O)C6N(C2=O)CCO6 373.50 unknown https://doi.org/10.3987/COM-00-9105
8-Hydroxy-13-(2-hydroxyethyl)-11-methyl-19-methylidene-13-azapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-6-one 73800058 Click to see 359.50 unknown https://doi.org/10.3987/COM-92-6243
https://doi.org/10.1016/J.BSE.2003.07.001
Spiramine A 441757 Click to see 399.50 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/S0014-2999(02)01627-8
https://doi.org/10.1248/CPB.35.1670
Spiramine C 20056314 Click to see CC12CCCC34C1CC(C56C3CC(CC5)C(=C)C6O)OC4N7C2OCC7 357.50 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/S0014-2999(02)01627-8
https://doi.org/10.1016/J.BSE.2003.07.001
https://doi.org/10.1248/CPB.35.1670
Spiramine D 20056313 Click to see 357.50 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1016/J.BSE.2003.07.001
https://doi.org/10.1248/CPB.35.1670
Spiramine Q 101915842 Click to see 375.50 unknown https://doi.org/10.1055/S-2000-8571
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.1016/J.BSE.2003.07.001
Spirasine I 11953913 Click to see 355.50 unknown https://doi.org/10.3987/R-1986-08-2105
Spiredine 11953914 Click to see 353.50 unknown https://doi.org/10.1007/BF00570232
https://doi.org/10.3987/R-1987-01-0019
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids / Hetisine-type diterpenoid alkaloids
(16S)-16-hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-one 5321444 Click to see 311.40 unknown via CMAUP database
(16S)-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecane-16,19-diol 5321445 Click to see CC12CCCC34C1C5(CC67C3C(C(CC6C4N5C2)C(=C)C7)O)O 313.40 unknown via CMAUP database
[(16S)-16-hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-yl] acetate 5321446 Click to see 355.50 unknown via CMAUP database
Spiradine A 441756 Click to see 311.40 unknown https://doi.org/10.1016/S0040-4039(00)83995-7
https://doi.org/10.1007/BF00570232
Spirasine XII 189311 Click to see 327.40 unknown https://doi.org/10.1021/NP50055A005
Spirasine XIV 189312 Click to see CC12CCCC34C1C5(CC67C3CC(C(C6C4N5C2)O)C(=C)C7)O 313.40 unknown https://doi.org/10.1021/NP50055A005
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids / Isoatisine-type diterpenoid alkaloids
(6-Hydroxy-11-methyl-5-methylidene-12-oxo-16-oxa-13-azahexacyclo[9.6.3.24,7.01,10.02,7.013,17]docosan-8-yl) acetate 73657351 Click to see 415.50 unknown https://doi.org/10.1016/S0014-2999(02)01627-8
https://doi.org/10.1007/S11094-015-1200-5
[(1R,2R,4S,7R,8S,9S,10S,11R,17S)-8-acetyloxy-11-methyl-5-methylidene-12-oxo-16-oxa-13-azahexacyclo[9.6.3.24,7.01,10.02,7.013,17]docosan-9-yl] acetate 163049172 Click to see CC(=O)OC1C2C3(CCCC2(C4CC5CCC4(C1OC(=O)C)CC5=C)C6N(C3=O)CCO6)C 457.60 unknown https://doi.org/10.1021/NP0004911
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
(1R,2R,4S,5R,6R,7R,8R,10R,11R)-5,6,8-trihydroxy-5,11-dimethyl-13-oxapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-12-one 15381694 Click to see CC12CCCC3(C1CC(C45C3CC(CC4)C(C5O)(C)O)O)COC2=O 350.40 unknown https://doi.org/10.1016/S0031-9422(97)00791-7
(1R,2R,4S,6S,7R,8R,10R,11R)-6,8-dihydroxy-11-methyl-5-methylidene-13-oxapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-12-one 102317158 Click to see CC12CCCC3(C1CC(C45C3CC(CC4)C(=C)C5O)O)COC2=O 332.40 unknown https://doi.org/10.1016/S0031-9422(97)00791-7
(1R,2R,4S,7R,8R,9R,10R,11R)-8-hydroxy-11-(hydroxymethyl)-11-methyl-5-methylidene-16-oxapentacyclo[7.5.2.24,7.01,10.02,7]octadecan-15-one 162962071 Click to see CC1(CCCC23C1C(C(C45C2CC(CC4)C(=C)C5)O)OC3=O)CO 332.40 unknown https://doi.org/10.1002/HLCA.200790140
6,8-Dihydroxy-11-methyl-5-methylidene-13-oxapentacyclo[9.3.3.24,7.01,10.02,7]nonadecan-14-one 163105777 Click to see 332.40 unknown https://doi.org/10.1016/S0031-9422(97)00791-7
8-Hydroxy-11-(hydroxymethyl)-11-methyl-5-methylidene-16-oxapentacyclo[7.5.2.24,7.01,10.02,7]octadecan-15-one 162962070 Click to see CC1(CCCC23C1C(C(C45C2CC(CC4)C(=C)C5)O)OC3=O)CO 332.40 unknown https://doi.org/10.1002/HLCA.200790140
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
Indoxyl-beta-D-glucoside 441564 Click to see 295.29 unknown via CMAUP database
> Organoheterocyclic compounds / Azaspirodecane derivatives
Spiramide 68186 Click to see C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCOC4=CC=C(C=C4)F 383.50 unknown https://doi.org/10.1021/NP0004911
> Organoheterocyclic compounds / Indoles and derivatives / Indolines
(2E)-2-(3-oxo-1H-indol-2-ylidene)-1H-indol-3-one 5318432 Click to see C1=CC=C2C(=C1)C(=O)C(=C3C(=O)C4=CC=CC=C4N3)N2 262.26 unknown via CMAUP database
(3Z)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one 5318433 Click to see C1=CC=C2C(=C1)C(=C3C(=O)C4=CC=CC=C4N3)C(=O)N2 262.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens
9-(7-Hydroxy-3,7-dimethylocta-2,5-dienoxy)furo[3,2-g]chromen-7-one 54519294 Click to see 354.40 unknown https://doi.org/10.3987/COM-89-S80
https://doi.org/10.1016/0031-9422(94)00644-9
https://doi.org/10.3987/COM-00-9105
https://doi.org/10.1248/CPB.35.1670
> Phenylpropanoids and polyketides / Flavonoids / Flavones / 8-prenylated flavones
Pseudosemiglabrin 156341 Click to see CC(=O)OC1C2C(OC3=C2C4=C(C=C3)C(=O)C=C(O4)C5=CC=CC=C5)OC1(C)C 392.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
3,5,7-trihydroxy-2-[3-hydroxy-4-[(2S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one 44259230 Click to see 464.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
3,5-dihydroxy-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2-[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]chromen-4-one 101422383 Click to see CC1C(C(C(C(O1)OC2=CC=C(C=C2)C3=C(C(=O)C4=C(C=C(C=C4O3)OC5C(C(C(C(O5)C)O)O)O)O)O)O)O)O 578.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / Rotenoids / Rotenones
(1R,14S)-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one 92211494 Click to see CC1(C=CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC)C 394.40 unknown via CMAUP database
(1S,14R)-14-hydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one 92296469 Click to see 410.40 unknown via CMAUP database
Deguelin 107935 Click to see 394.40 unknown via CMAUP database
Dehydrodeguelin 3083803 Click to see 392.40 unknown via CMAUP database
Rotenone 6758 Click to see CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC 394.40 unknown via CMAUP database
Sumatrol 442824 Click to see CC(=C)C1CC2=C(O1)C=C(C3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC)O 410.40 unknown via CMAUP database

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