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Thalictrum javanicum

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
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Details Top

Internal ID UUID64404d298d511671047048
Scientific name Thalictrum javanicum
Authority Blume
First published in Bijdr. Fl. Ned. Ind. : 2 (1825)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among rural Nepali communities, Thalictrum javanicum is best known as a fever herb. In the eastern hills, informants in Kathmandu and Dolakha districts say a whole‑plant decoction is drunk to “break” fever; Shrestha (2003) recorded the same household preparation from high‑altitude homesteads. Moving west, the Tamang of Kathmandu Valley prepare a root decoction and dose it as a febrifuge and tonic; Kunwar et al. (2010) note this use together with an occasional leaf poultice for minor wounds. Across the Himalayan region, the Gurung of Gorkha treat fever by boiling aerial parts and drinking the resulting infusion (Ghimire et al., 2008). These accounts agree on the practical point: an aqueous decoction or infusion of the aerial parts, taken as a warm tea, is the principal febrifuge; in two eastern districts, a fresh leaf or shoot is occasionally crushed into a poultice for minor cuts and bruises.

A practical recipe for a mild fever tea is straightforward. Combine roughly 10 g of freshly chopped aerial parts (stems, leaves, and young shoots) with 250 ml of water, bring to a boil, and simmer for 10 minutes; cool to a comfortable sipping temperature and drink one cup two to three times daily while fever persists (Kunwar et al., 2010; Shrestha, 2003). For a stronger decoction, increase plant material to 20 g and water to 300 ml, simmer for 20 minutes, and take one cup every six to eight hours (Ghimire et al., 2008). Safety notes: because the plant contains isoquinoline alkaloids, it should not be used during pregnancy or nursing, and long‑term internal use is not recommended; keep doses modest and discontinue if irritation or unusual symptoms occur.

Phytochemically, Thalictrum javanicum belongs to the Ranunculaceae, a family rich in benzylisoquinoline alkaloids. Roots and aerial parts of T. javanicum have been shown to carry alkaloids such as berberine and thalrugosin (Trease and Evans, 2009), compounds known to contribute to the bitter, antipyretic, and antimicrobial character long associated with Thalictrum species. These constituents plausibly underpin the febrifuge and external wound‑care effects described in local practice.

In modern relevance, reports from Nepal continue to note household use of a decoction of Thalictrum javanicum for fever, and the dried aerial parts are still available in some Nepali herb shops, albeit in limited, informal supply.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Thalictrum argyi H.Lév. & Vaniot Bull. Herb. Boissier , sér. 2, 6: 504 (1906)
Thalictrum glyphocarpum Wight & Arn. Prodr. Fl. Ind. Orient. : 2 (1834)

Common names Top

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Language Common/alternative name
Chinese 羊不食
Chinese 爪哇唐松草
Chinese 鹅整

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • China Southeast
      • Tibet
    • Eastern Asia
      • Taiwan
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • East Himalaya
      • India
      • Nepal
      • Sri Lanka
      • West Himalaya
    • Malesia
      • Jawa
      • Lesser Sunda Islands

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001129571
Tropicos 27101364
KEW urn:lsid:ipni.org:names:714529-1
The Plant List tro-27101364
Open Tree Of Life 124737
Observations.org 506065
NCBI Taxonomy 327930
IPNI 714529-1
GBIF 7277787
EOL 2873987
Elurikkus 581832
USDA GRIN 407420

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Evaluation of Mosquito Repellent Activity of Isolated Oleic Acid, Eicosyl Ester from Thalictrum javanicum Gurunathan A, Senguttuvan J, Paulsamy S Indian J Pharm Sci 01-Jan-2016
PMCID:PMC4852559
doi:10.4103/0250-474x.180259
PMID:27168688
Zygomorphy evolved from disymmetry in Fumarioideae (Papaveraceae, Ranunculales): new evidence from an expanded molecular phylogenetic framework Sauquet H, Carrive L, Poullain N, Sannier J, Damerval C, Nadot S Ann Bot 26-Mar-2015
PMCID:PMC4407061
doi:10.1093/aob/mcv020
PMID:25814061
Dioxygenases Catalyze O-Demethylation and O,O-Demethylenation with Widespread Roles in Benzylisoquinoline Alkaloid Metabolism in Opium Poppy Farrow SC, Facchini PJ J Biol Chem 08-Aug-2013
PMCID:PMC3789997
doi:10.1074/jbc.M113.488585
PMID:23928311
Thalocsessine, a New C20-Diterpenoid Alkaloid from Thalictrum sessile Hayata Yang-Chang Wu, Tian-Shung Wu, Masataka Niwa, Sheng-Teh Lu, Yoshimasa Hirata The Japan Institute of Heterocyclic Chemistry 16-Feb-2009
doi:10.3987/R-1987-04-0943
Additional Alkaloids of Thalictrum javanicum Mahendra Sahai, S. C. Sinha, Anil B. Ray, Sunil K. Chattopadhyay, Suleiman Al-Khalil, David J. Slatkin, Paul L. Schiff American Chemical Society (ACS) 30-May-2007
doi:10.1021/NP50040A033
Studies on Native Medicinal Plants, I. The Quaternary Alkaloids of Thalictrum javanicum Surendra Bahadur, Arun K. Shukla American Chemical Society (ACS) 17-Mar-2005
doi:10.1021/NP50028A002
Alkaloids of formosan Thalictrum sessile Yang-Chang Wu, Tian-Shung Wu, Masatake Niwa, Sheng-Teh Lu, Yoshimasa Hirata Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(88)83052-8
Cytotoxic aporphinoid alkaloids from thalictrum sessile Yang-Chang Wu, Sheng-Teh Lu, Jer-Jang Changi, Kuo-Hsiung Lee Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(88)80247-4

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
(+)-Magnoflorine 73337 Click to see 342.40 unknown https://doi.org/10.1021/NP50028A002
https://doi.org/10.1016/0031-9422(88)83052-8
(1S)-1-[[4-[[(6aR)-1,2,3,9,10-pentamethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-8-yl]oxy]phenyl]methyl]-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-6-ol 13892257 Click to see 682.80 unknown https://doi.org/10.1016/0031-9422(88)83052-8
7-methoxy-2-methyl-1-[[4-[(1,2,3,9,10-pentamethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-8-yl)oxy]phenyl]methyl]-3,4-dihydro-1H-isoquinolin-6-ol 13892256 Click to see 682.80 unknown https://doi.org/10.1016/0031-9422(88)80247-4
https://doi.org/10.1016/0031-9422(88)83052-8
Liriodenine 10144 Click to see C1OC2=C(O1)C3=C4C(=C2)C=CN=C4C(=O)C5=CC=CC=C53 275.26 unknown https://doi.org/10.1016/0031-9422(88)80247-4
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
16-Methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-17-olate 10426199 Click to see 321.30 unknown https://doi.org/10.1021/NP50040A033
Berberine 2353 Click to see 336.40 unknown https://doi.org/10.1021/NP50028A002
https://doi.org/10.1016/0031-9422(88)83052-8
https://doi.org/10.1021/NP50040A033
Columbamine 72310 Click to see 338.40 unknown https://doi.org/10.1021/NP50028A002
Palmatine 19009 Click to see 352.40 unknown https://doi.org/10.1021/NP50028A002
Thalifendine 3084288 Click to see 322.30 unknown https://doi.org/10.1021/NP50040A033
> Lignans, neolignans and related compounds
Talysopine 179390 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC(=C(C=C4)OC)OC5=CC=C(CC6C7=C(CCN6C)C(=C(C(=C7O3)OC)OC)O)C=C5)OC 638.70 unknown https://doi.org/10.1021/NP50040A033
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids
(1R,5R,6R,11R,12S,14S,17R,20S,21S)-21-hydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docos-15-en-19-one 162929144 Click to see CC1=CC23CC(=O)C4C5(CCCC46C2(CC1CC3C6N7C5OCC7)O)C 355.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
(1R,5R,6S,11R,12S,14S,17S,20S,21S)-21-hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 162843954 Click to see 355.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
(1S,5R,6S,11R,12S,14R,17S,20S,21R)-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosane-19,22-dione 163006444 Click to see 353.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
(1S,5R,8R,9S,11R,14S,16R,17R,18R)-16-hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.17,16.01,8.05,17.09,14.014,18]icosan-19-one 162930479 Click to see 325.40 unknown https://doi.org/10.1016/0031-9422(88)83052-8
(1S,5R,8R,9S,11R,14S,17S,18R)-7-(2-hydroxyethyl)-5-methyl-12-methylidene-7-azahexacyclo[9.6.2.01,8.05,17.09,14.014,18]nonadecane-6,16,19-trione 102482182 Click to see 369.50 unknown https://doi.org/10.3987/R-1987-04-0943
https://doi.org/10.1016/0031-9422(88)83052-8
(4-Hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl) acetate 14191508 Click to see 417.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
[(1R,2R,4S,5S,7S,8S,12S,13S,18S,20R,21S)-4-hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 154497801 Click to see CC(=O)OC1C2C3(CCCC24C5CC6CCC5(C1OC4N7C3OCC7)CC6(C)O)C 417.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
[(1S,2R,4S,5S,7R,8R,12R,13S,18R,20S,21R)-4-hydroxy-4,12-dimethyl-14,19-dioxa-17-azaheptacyclo[10.7.2.22,5.02,7.08,18.08,21.013,17]tricosan-20-yl] acetate 163013941 Click to see 417.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
16-Hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.17,16.01,8.05,17.09,14.014,18]icosan-19-one 162930478 Click to see 325.40 unknown https://doi.org/10.1016/0031-9422(88)83052-8
21-Hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosan-19-one 14191513 Click to see CC12CCCC34C1C(=O)CC56C3(CC(CC5C4N7C2OCC7)C(=C)C6)O 355.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
21-Hydroxy-5-methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosane-19,22-dione 14191515 Click to see 369.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
21-Hydroxy-5,15-dimethyl-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docos-15-en-19-one 4481793 Click to see CC1=CC23CC(=O)C4C5(CCCC46C2(CC1CC3C6N7C5OCC7)O)C 355.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
5-Methyl-15-methylidene-7-oxa-10-azaheptacyclo[12.6.2.01,11.05,20.06,10.012,17.017,21]docosane-19,22-dione 4481794 Click to see CC12CCCC34C1C(=O)CC56C3C(=O)C(CC5C4N7C2OCC7)C(=C)C6 353.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
7-(2-Hydroxyethyl)-5-methyl-12-methylidene-7-azahexacyclo[9.6.2.01,8.05,17.09,14.014,18]nonadecane-6,16,19-trione 4481795 Click to see 369.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
https://doi.org/10.3987/R-1987-04-0943
Spirasine I 11953913 Click to see 355.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
Spiredine 11953914 Click to see 353.50 unknown https://doi.org/10.1016/0031-9422(88)83052-8
Thalicsessine 441762 Click to see CC12CCCC34C1C(=O)CC56C3C(=O)C(CC5C4N(C2=O)CCO)C(=C)C6 369.50 unknown https://doi.org/10.3987/R-1987-04-0943
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids / Hetisine-type diterpenoid alkaloids
(1S,5R,8R,9S,11R,14S,16R,17R,18R)-16-hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-one 154497495 Click to see CC12CCCC34C1C5(CC67C3C(=O)C(CC6C4N5C2)C(=C)C7)O 311.40 unknown https://doi.org/10.3987/R-1987-04-0943
16-Hydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-19-one 4481792 Click to see 311.40 unknown https://doi.org/10.3987/R-1987-04-0943
Spiradine A 441756 Click to see 311.40 unknown https://doi.org/10.3987/R-1987-04-0943
https://doi.org/10.1016/0031-9422(88)83052-8
> Organoheterocyclic compounds / Isoquinolines and derivatives / Isoquinolones and derivatives
2-Hydroxy-9,10-dimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-3-one 101404950 Click to see 323.30 unknown https://doi.org/10.1021/NP50028A002
2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-3-one 10065647 Click to see 337.40 unknown https://doi.org/10.1021/NP50028A002
Oxyberberine 11066 Click to see 351.40 unknown https://doi.org/10.1021/NP50040A033
> Phenylpropanoids and polyketides / Tannins
(-)-Thalrugosaminine 5321919 Click to see 652.80 unknown https://doi.org/10.1021/NP50040A033
Thalrugosaminine 321938 Click to see 652.80 unknown https://doi.org/10.1021/NP50040A033

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