Details Top

Internal ID UUID64400cb06e1f3169700033
Scientific name Berberis cretica
Authority L.
First published in Sp. Pl. : 331 (1753)

Ethnobotanical Use Top

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General Uses Top

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Common products:
The fruits of Berberis cretica are harvested locally and used in small-scale food products, primarily as jam.

Industrial and craft applications:
No documented industrial or craft applications specific to B. cretica are available; references focus on other Berberis species for dye or tannin.

Food and beverages (non-medicinal):
Edible berries are used in jams, preserves, and occasionally as a souring ingredient. Berberis is included in the “Famine food” and “Wild food” flora of the Levant and is cultivated in parts of the eastern Mediterranean for its fruit, which is marketed locally as a food ingredient. Any beverage use (e.g., as a flavoring or acidulant) is correspondingly small-scale.

Colorants and tanning:
No reliable records report dye or tannin extraction from B. cretica itself. In contrast, roots of other Berberis species (e.g., B. vulgaris) have historically been used for yellow dyes and for tanning due to berberine and other alkaloids; these uses are not established for B. cretica.

Wood and fiber:
No documented timber, pulp, or fiber use is reported for B. cretica.

Fragrance and cosmetics:
No documented use in fragrance or cosmetics is recorded for B. cretica.

Properties relevant to use:
Fruits have measurable acidity and moderate sugar content, consistent with other Berberis fruit used for preserves; exact values for B. cretica are not reported in the provided sources.

Standards and regulation:
No species-specific standards (ISO/ASTM/EN) or national regulatory frameworks for B. cretica products are reported.

Sustainability and sourcing:
The species is collected from the wild in the eastern Mediterranean and Balkans, and there is no evidence of large-scale cultivation for commercial use. Local harvesting may be unmanaged and sensitive to overharvest in some areas; no quantitative sustainability or conservation data specific to B. cretica were found in the consulted sources.

Synonyms Top

Scientific name Authority First published in
Berberis vulgaris var. cretica (L.) Hook.f. & Thomson Fl. Brit. India 1: 109 (1872)
Berberis cretica var. serratifolia Poir. ex Loudon Arbor. Frutic. Brit. 1: 305 1838
Berberis sinensis var. cretica (L.) Regel Trudy Imp. S.-Peterburgsk. Bot. Sada 2: 417 (1873)
Berberis cretica var. serratifolia Poir. ex DC. Syst. Nat. 2: 9 (1821)

Common names Top

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Language Common/alternative name
Bulgarian критски кисел трън
Hebrew ברברית הלבנון
Russian Барбарис критский
Chinese 克里特小檗

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000563031
Tropicos 3500353
KEW urn:lsid:ipni.org:names:106572-1
The Plant List kew-2673664
Open Tree Of Life 5727814
Observations.org 115502
NCBI Taxonomy 1433307
IPNI 106572-1
iNaturalist 495806
GBIF 3981350
EPPO BEBCR
Elurikkus 614176
USDA GRIN 6844
Wikipedia Berberis_cretica

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Therapeutic Role of Alkaloids and Alkaloid Derivatives in Cancer Management Olofinsan K, Abrahamse H, George BP Molecules 22-Jul-2023
PMCID:PMC10386240
doi:10.3390/molecules28145578
PMID:37513450
Evaluation of the Antioxidant and Anti-Lipoxygenase Activity of Berberis vulgaris L. Leaves, Fruits, and Stem and Their LC MS/MS Polyphenolic Profile Och A, Olech M, Bąk K, Kanak S, Cwener A, Cieśla M, Nowak R Antioxidants (Basel) 21-Jul-2023
PMCID:PMC10376855
doi:10.3390/antiox12071467
PMID:37508005
In Vitro Propagation of Origanum scabrum (Boiss. & Heldr.): An Endemic Medicinal Plant of Greece Alexopoulos AA, Kartsonas E, Karras S, Mavrommati E, Petropoulos SA, Papafotiou M Plants (Basel) 26-May-2023
PMCID:PMC10255548
doi:10.3390/plants12112118
PMID:37299098
An Ethnobotanical Investigation into the Traditional Uses of Mediterranean Medicinal and Aromatic Plants: The Case of Troodos Mountains in Cyprus Savvides AM, Stavridou C, Ioannidou S, Zoumides C, Stylianou A Plants (Basel) 02-Mar-2023
PMCID:PMC10005048
doi:10.3390/plants12051119
PMID:36903979
Determination of the Total Phenolics Content and Antioxidant Activity of Extracts from Parts of Plants from the Greek Island of Crete Kalpoutzakis E, Chatzimitakos T, Athanasiadis V, Mitakou S, Aligiannis N, Bozinou E, Gortzi O, Skaltsounis LA, Lalas SI Plants (Basel) 01-Mar-2023
PMCID:PMC10005234
doi:10.3390/plants12051092
PMID:36903954
Diversity of Ascomycota in Jilin: Introducing Novel Woody Litter Taxa in Cucurbitariaceae Su W, Xu R, Bhunjun CS, Tian S, Dai Y, Li Y, Phukhamsakda C J Fungi (Basel) 26-Aug-2022
PMCID:PMC9501381
doi:10.3390/jof8090905
PMID:36135630
About spirals and pores: Xylariaceae with remarkable germ loci Voglmayr H, Tello S, Jaklitsch WM, Friebes G, Baral HO, Fournier J Persoonia 13-Aug-2022
PMCID:PMC10792227
doi:10.3767/persoonia.2022.49.02
PMID:38234381
Natural Products-Based Metallic Nanoparticles as Antimicrobial Agents Susanti D, Haris MS, Taher M, Khotib J Front Pharmacol 02-Jun-2022
PMCID:PMC9205242
doi:10.3389/fphar.2022.895616
PMID:35721199
Special Issue “Natural Plant Substances—Structural and Application Aspects: A Theme Issue in Honor of Professor Wieslaw Oleszek” Żuchowski J, Stochmal A, Kozachok S, Pérez AJ, Pecio Ł Molecules 26-May-2022
PMCID:PMC9182290
doi:10.3390/molecules27113430
PMID:35684367
Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin Grabarska A, Wróblewska-Łuczka P, Kukula-Koch W, Łuszczki JJ, Kalpoutzakis E, Adamczuk G, Skaltsounis AL, Stepulak A Molecules 15-Oct-2021
PMCID:PMC8538708
doi:10.3390/molecules26206253
PMID:34684834
Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity Naldi M, Brusotti G, Massolini G, Andrisano V, Temporini C, Bartolini M Molecules 20-Jul-2021
PMCID:PMC8307647
doi:10.3390/molecules26144376
PMID:34299650
Antioxidant Activity and Chemical Characteristics of Supercritical CO2 and Water Extracts from Willow and Poplar Ostolski M, Adamczak M, Brzozowski B, Wiczkowski W Molecules 21-Jan-2021
PMCID:PMC7866000
doi:10.3390/molecules26030545
PMID:33494378
Topical Collection “Pharmacology of Medicinal Plants” Romano B, Lucariello G, Capasso R Biomolecules 14-Jan-2021
PMCID:PMC7828774
doi:10.3390/biom11010101
PMID:33466709
Contribution to the Orophilous Cushion-Like Vegetation of Central-Southern and Insular Greece Musarella CM, Brullo S, del Galdo GG Plants (Basel) 30-Nov-2020
PMCID:PMC7760968
doi:10.3390/plants9121678
PMID:33266088
Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells Okon E, Kukula-Koch W, Halasa M, Jarzab A, Baran M, Dmoszynska-Graniczka M, Angelis A, Kalpoutzakis E, Guz M, Stepulak A, Wawruszak A Biomolecules 10-Nov-2020
PMCID:PMC7696229
doi:10.3390/biom10111532
PMID:33182753

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / 6,6a-secoaporphines
4-Phenanthrenol, 1-(2-(dimethylamino)ethyl)-3,5,6-trimethoxy- 179804 Click to see 355.40 unknown https://doi.org/10.1021/NP50043A025
> Alkaloids and derivatives / Aporphines
(+)-Glaucine 16754 Click to see 355.40 unknown https://doi.org/10.1021/NP50043A025
(+)-Magnoflorine 73337 Click to see 342.40 unknown https://doi.org/10.1021/NP50043A025
(6As)-2,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol 6992288 Click to see 341.40 unknown https://doi.org/10.1021/NP50043A025
Isoboldine 133323 Click to see 327.40 unknown https://doi.org/10.1021/NP50043A025
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
Berberine 2353 Click to see 336.40 unknown https://doi.org/10.1021/NP50043A025
Canadine 34458 Click to see COC1=C(C2=C(CC3C4=CC5=C(C=C4CCN3C2)OCO5)C=C1)OC 339.40 unknown https://doi.org/10.1021/NP50043A025
Columbamine 72310 Click to see 338.40 unknown https://doi.org/10.1021/NP50043A025
Palmatine 19009 Click to see 352.40 unknown https://doi.org/10.1021/NP50043A025
> Lignans, neolignans and related compounds
(1R,14S)-20,25-dimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene-9,21-diol 275968 Click to see 594.70 unknown https://doi.org/10.1021/NP50043A025
(4aR,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-9,21,22,26-tetramethoxy-4,17-dimethyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido(2',3':17,18)(1,10)dioxacycloeicosino(2,3,4-ij)isoquinoline 100231 Click to see 622.70 unknown https://doi.org/10.1021/NP50043A025
(4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-21,26-dimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido(2',3':17,18)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinoline-12,22-diol 441064 Click to see 594.70 unknown https://doi.org/10.1021/NP50043A025
1-Isotetrandrine 5351212 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC 622.70 unknown https://doi.org/10.1021/NP50043A025
20,21,25-Trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo(22.6.2.23,6.18,12.114,18.027,31.022,33)hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-9-ol 10170 Click to see 608.70 unknown https://doi.org/10.1021/NP50043A025
Aromoline 362574 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC 594.70 unknown https://doi.org/10.1021/NP50043A025
Berbamine 275182 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC 608.70 unknown https://doi.org/10.1021/NP50043A025
Oxyacanthine 442333 Click to see 608.70 unknown https://doi.org/10.1021/NP50043A025
Thalrugosine, (+)- 100257 Click to see 608.70 unknown https://doi.org/10.1021/NP50043A025
> Organoheterocyclic compounds / Isoquinolines and derivatives
793JX7VC6J 457914 Click to see 321.30 unknown https://doi.org/10.1021/NP50043A025
> Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines
(1S)-1,2,3,4-Tetrahydro-1-((4-(2-hydroxy-5-(((1R)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenyl)methyl)-6-methoxy-2-methyl-7-isoquinolinol 440585 Click to see 596.70 unknown https://doi.org/10.1021/NP50043A025
> Organoheterocyclic compounds / Isoquinolines and derivatives / Isoquinolones and derivatives
2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-3-one 10065647 Click to see 337.40 unknown https://doi.org/10.1021/NP50043A025
Oxyberberine 11066 Click to see 351.40 unknown https://doi.org/10.1021/NP50043A025

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