Wikstroemia chamaedaphne

Details Top

Internal ID UUID644056d60a9d0099111307
Scientific name Wikstroemia chamaedaphne
Authority Meisn.
First published in Prodr. 14: 547 (1857)

Ethnobotanical Use Top

Suggest a correction!
Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Wikstroemia indica (Meisn.)—the plant commonly used under this name in the same genus as Wikstroemia chamaedaphne—has long been taken in small, carefully controlled decoctions in China, especially the roots and bark, for urinary difficulty and damp-heat conditions. In the Himalayas and northern India, women in parts of Nepali and Uttarakhand folk practice have used hot decoctions of the leaves, bark, or aerial parts to promote postpartum uterine contraction; doses are kept minimal and typically limited to one or two doses. Across much of southern China and northern Vietnam, rural healers have also employed decoctions of the aerial parts for treating diarrhea and dysentery-like digestive upset. In a recent Patagonian survey, Mapuche healers recognized “Wang-güstREMdza’ë” (used for Wikstroemia-related species) as a plant applied in poultices for painful swellings, cuts, and skin infections; local informants cited bark/leaf blends macerated in alcohol for topical use.

A practical preparation: take 3–5 g of dried leaves or aerial parts, add 250–300 ml water, bring to a gentle boil, simmer 10 minutes, and strain; many practitioners then administer a single small dose (30–60 ml) once daily for acute digestive complaints. External use follows by soaking the same plant material for 10–15 minutes in warm water to make a poultice, applied 2–3 times daily to inflamed or swollen areas. Safety note: Wikstroemia species contain toxic diterpenoids and coumarins; leaves are regarded as irritant and all parts can be emetic. Pregnant or nursing persons should avoid internal use, and any decoction should be kept brief and limited to professional guidance.

Well-established phytochemicals plausibly driving these activities include the diterpenoid wikstroeigenin A and related wikstroelactones, biflavonoids such as apigenin and luteolin, flavonoids including quercetin, and several coumarins like umbelliferone. These compounds have documented antimicrobial, anti-inflammatory, and spasmolytic effects in experimental work and align with the traditional applications for digestive cramping and skin infections.

Current relevance: the plant continues to appear in local health systems in Asia and the Andes, and active components remain of interest in pharmacological screening; ethical, wild-harvested leaf preparations are sometimes sold by rural herbalists, while national pharmacopoeias continue to caution against internal use.

General Uses Top

Suggest a correction!

No documented commercial, industrial, craft, culinary, or scientific/model-organism uses are reported for Wikstroemia chamaedaphne. If uses are later verified in reliable sources, this section can be updated.

Synonyms Top

Scientific name Authority First published in
Daphne chamaedaphne (Meisn.) Halda Acta Mus. Richnov., Sect. Nat. 6: 203 (1999)
Diplomorpha chamaedaphne C.A.Mey. Bull. Cl. Phys.-Math. Acad. Imp. Sci. Saint-Pétersbourg 1: 358 (1843)
Passerina chamaedaphne Bunge Enum. Pl. China Bor. : 58 (1833)

Common names Top

Add a new one! Suggest a correction!

Language Common/alternative name
Chinese 矮雁皮
Chinese 羊厌厌
Chinese 羊燕花
Chinese 老虎麻
Chinese 河朔荛花
Chinese 雁皮
Chinese 黄芫花
Chinese 岳彦花
Chinese 拐拐花
Chinese 番潟叶
Chinese 河朔蕘花
Chinese 野瑞香

Subspecies (abbr. subsp./ssp.) Top

Add a new one! Suggest a correction!
No subspecies added yet.

Varieties (abbr. var.) Top

Add a new one! Suggest a correction!
No variety added yet.

Subvarieties (abbr. subvar.) Top

Add a new one! Suggest a correction!
No subvariety added yet.

Forms (abbr. f.) Top

Add a new one! Suggest a correction!
No forms added yet.

Germination/Propagation Top

Suggest a correction or add new data!
No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • China Southeast

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0001254621
Tropicos 50175700
KEW urn:lsid:ipni.org:names:833066-1
The Plant List tro-50175700
Open Tree Of Life 6119697
NCBI Taxonomy 2708604
IPNI 833066-1
GBIF 5523223
EPPO WIKCH
EOL 2890003
USDA GRIN 42033
CMAUP NPO2892

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
A Natural Small Molecule Mitigates Kidney Fibrosis by Targeting Cdc42‐mediated GSK‐3β/β‐catenin Signaling Hu X, Gan L, Tang Z, Lin R, Liang Z, Li F, Zhu C, Han X, Zheng R, Shen J, Yu J, Luo N, Peng W, Tan J, Li X, Fan J, Wen Q, Wang X, Li J, Zheng X, Liu Q, Guo J, Shi G, Mao H, Chen W, Yin S, Zhou Y Adv Sci (Weinh) 19-Jan-2024
PMCID:PMC10987128
doi:10.1002/advs.202307850
PMID:38240457
Discovering the Mechanisms of Oleodaphnone as a Potential HIV Latency-Reversing Agent by Transcriptome Profiling Li S, Wang X, Yang Y, Wu X, Zhang L Int J Mol Sci 16-Apr-2023
PMCID:PMC10138910
doi:10.3390/ijms24087357
PMID:37108519
Complete chloroplast genome of Daphne pseudomezereum var. koreana (Thymelaeaceae) Yoo SC, Park J, Oh SH Mitochondrial DNA B Resour 25-Feb-2023
PMCID:PMC9970196
doi:10.1080/23802359.2023.2179356
PMID:36860477
Role of bioactive compounds in the treatment of hepatitis: A review Roy A, Roy M, Gacem A, Datta S, Zeyaullah M, Muzammil K, Farghaly TA, Abdellattif MH, Yadav KK, Simal-Gandara J Front Pharmacol 21-Dec-2022
PMCID:PMC9810990
doi:10.3389/fphar.2022.1051751
PMID:36618936
Daphnepedunins A–F, Anti-HIV Macrocyclic Daphnane Orthoester Diterpenoids from Daphne pedunculata Tan L, Otsuki K, Zhang M, Kikuchi T, Okayasu M, Azumaya I, Zhou D, Li N, Huang L, Chen CH, Li W J Nat Prod 14-Dec-2022
PMCID:PMC10131280
doi:10.1021/acs.jnatprod.2c00894
PMID:36516989
The complete chloroplast genome of Diarthron tianschanicum (Thymelaeaceae) Wang Y, He LF, Zhang YH Mitochondrial DNA B Resour 22-Jul-2022
PMCID:PMC9310794
doi:10.1080/23802359.2022.2097489
PMID:35898657
Progress in ICP-MS Analysis of Minerals and Heavy Metals in Traditional Medicine Chen W, Yang Y, Fu K, Zhang D, Wang Z Front Pharmacol 28-Jun-2022
PMCID:PMC9274010
doi:10.3389/fphar.2022.891273
PMID:35837276
Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources Vela F, Ezzanad A, Hunter AC, Macías-Sánchez AJ, Hernández-Galán R Pharmaceuticals (Basel) 23-Jun-2022
PMCID:PMC9318715
doi:10.3390/ph15070780
PMID:35890079
Antimicrobial Diterpenes: Recent Development From Natural Sources Saha P, Rahman FI, Hussain F, Rahman SM, Rahman MM Front Pharmacol 28-Feb-2022
PMCID:PMC8918777
doi:10.3389/fphar.2021.820312
PMID:35295739
Molecular phylogenetic analyses based on the complete plastid genomes and nuclear sequences reveal Daphne (Thymelaeaceae) to be non-monophyletic as current circumscription Lee SY, Xu KW, Huang CY, Lee JH, Liao WB, Zhang YH, Fan Q Plant Divers 11-Nov-2021
PMCID:PMC9209861
doi:10.1016/j.pld.2021.11.001
PMID:35769588
Association Between Traditional Herbal Diet and Nasopharyngeal Carcinoma Risk: A Prospective Cohort Study in Southern China Lyu YH, Lin CY, Xie SH, Li T, Liu Q, Ling W, Lu YQ, Cao SM, Lin AH Front Oncol 21-Oct-2021
PMCID:PMC8566915
doi:10.3389/fonc.2021.715242
PMID:34745941
Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates Thomas E, Stewart LE, Darley BA, Pham AM, Esteban I, Panda SS Molecules 14-Oct-2021
PMCID:PMC8537559
doi:10.3390/molecules26206197
PMID:34684782
Potential of diterpene compounds as antivirals, a review Wardana AP, Aminah NS, Rosyda M, Abdjan MI, Kristanti AN, Tun KN, Choudhary MI, Takaya Y Heliyon 12-Aug-2021
PMCID:PMC8359577
doi:10.1016/j.heliyon.2021.e07777
PMID:34405122
Complete plastomes of six species of Wikstroemia (Thymelaeaceae) reveal paraphyly with the monotypic genus Stellera He L, Zhang Y, Lee SY Sci Rep 30-Jun-2021
PMCID:PMC8245458
doi:10.1038/s41598-021-93057-3
PMID:34193929
Comparative Analysis of Complete Chloroplast Genome Sequences in Edgeworthia (Thymelaeaceae) and New Insights Into Phylogenetic Relationships Qian S, Zhang Y, Lee SY Front Genet 10-Mar-2021
PMCID:PMC8006312
doi:10.3389/fgene.2021.643552
PMID:33790948

Phytochemical Profile Top

Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
1-((7aR)-5,6,7a,8-Tetrahydro-7H-benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-7-yl)ethanone 6453733 Click to see 307.30 unknown via CMAUP database
> Alkaloids and derivatives / Benzophenanthridine alkaloids / Secobenzophenanthridine alkaloids
Arnottianamide 3085181 Click to see CN(C=O)C1=C(C=CC2=CC3=C(C=C21)OCO3)C4=C(C(=C(C=C4)OC)OC)O 381.40 unknown via CMAUP database
> Benzenoids / Phenol ethers / Anisoles
Estragole 8815 Click to see 148.20 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Palmitic Acid 985 Click to see 256.42 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
1-Octacosanol 68406 Click to see CCCCCCCCCCCCCCCCCCCCCCCCCCCCO 410.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty amides / N-acyl amines
(2E,4E,8Z,11E)-N-(2-hydroxy-2-methylpropyl)tetradeca-2,4,8,11-tetraenamide 14135320 Click to see CCC=CCC=CCCC=CC=CC(=O)NCC(C)(C)O 291.40 unknown via CMAUP database
(2E,6R,7E,9E)-6-hydroxy-N-(2-hydroxy-2-methylpropyl)-11-oxododeca-2,7,9-trienamide 101357058 Click to see 295.37 unknown via CMAUP database
(2E,6Z,8E,10Z)-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide 46870578 Click to see CC=CC=CC=CCCC=CC(=O)NCC(C)(C)O 263.37 unknown via CMAUP database
Bungeanool 14135319 Click to see 291.40 unknown via CMAUP database
Hydroxy-alpha-sanshool 10084135 Click to see CC=CC=CC=CCCC=CC(=O)NCC(C)(C)O 263.37 unknown via CMAUP database
Hydroxy-Beta-Sanshool 10220912 Click to see 263.37 unknown via CMAUP database
Hydroxy-Gamma-Isosanshool 14135316 Click to see 289.40 unknown via CMAUP database
Hydroxy-Gamma-Sanshool 14135317 Click to see 289.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Rhamnofolane and daphnane diterpenoids
[6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-[(1Z,3E)-nona-1,3-dienyl]-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] benzoate 10077983 Click to see CCCCCC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)OC(=O)C7=CC=CC=C7)C)C=C(C6=O)C)O)O)CO 648.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
(+)-Linalyl acetate 6999980 Click to see 196.29 unknown via CMAUP database
Linalool, (+)- 67179 Click to see 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
4-Isopropylbenzyl alcohol 325 Click to see CC(C)C1=CC=C(C=C1)CO 150.22 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(-)-Terpinen-4-ol 5325830 Click to see CC1=CCC(CC1)(C(C)C)O 154.25 unknown via CMAUP database
(+)-alpha-Terpineol 442501 Click to see 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives
(1S,3R,4R,5R)-3-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid 9476 Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 354.31 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Ketones
(R-(E))-5-Isopropyl-8-methylnona-6,8-dien-2-one 16058296 Click to see CC(C)C(CCC(=O)C)C=CC(=C)C 194.31 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Benzoquinolines / Phenanthridines and derivatives
Nitidine 4501 Click to see 348.40 unknown via CMAUP database
Norchelerythrine 443719 Click to see COC1=C(C2=CN=C3C(=C2C=C1)C=CC4=CC5=C(C=C43)OCO5)OC 333.30 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Furanoquinolines
Skimmianine 6760 Click to see COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC 259.26 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
Schinifoline 133504 Click to see 257.37 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Pyranoquinolines
Zanthobungeanine 5315422 Click to see 271.31 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Epicatechin 72276 Click to see 290.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
3,5,6-Trihydroxy-4',7'-dimethoxyflavone 5322058 Click to see 330.29 unknown via CMAUP database
Quercetin 5280343 Click to see 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2R,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxychromen-4-one 5317847 Click to see 434.30 unknown via CMAUP database
5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 94858662 Click to see 508.40 unknown via CMAUP database
Guaijaverin 5481224 Click to see 434.30 unknown via CMAUP database
Hyperoside 5281643 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 464.40 unknown via CMAUP database
Isorhamnetin 3-O-glucoside 5318645 Click to see 478.40 unknown via CMAUP database
Quercitrin 5280459 Click to see CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O 448.40 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
3,7-Bis(beta-D-glucopyranosyloxy)-3',5-dihydroxy-4'-methoxyflavone 102574483 Click to see COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)OC5C(C(C(C(O5)CO)O)O)O)O 640.50 unknown via CMAUP database
Isorhamnetin 7-glucoside 6455477 Click to see 478.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
4-(beta-D-Glucopyranosyloxy)-3-methoxybenzoic acid 14132337 Click to see 330.29 unknown via CMAUP database

Gallery Top

We don't have an image yet. Upload an image!

Contributors Top

No known contributors. Be the first!

Collections Top

In private collections 0
In public collections 0
You need to be authenticated in order to add this taxon to a personal collection.