Content in this section summarizes historical and cultural records. It is not medical advice.
Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Colchicum autumnale, known as autumn crocus or meadow saffron, is recorded in European herbal practice as a traditional internal medicine for acute gout, most often prepared as a tincture made from the dried corm. In British herbal pharmacopeias the dried corm was macerated in alcohol to produce a 1:5 ethanol tincture used in short courses for gout pain. In Irish materia medica the corm was similarly prepared, while Swiss folk practitioners used a tincture, a topical poultice, or a decoction of the corm for rheumatic aches. ESCOP and the European Medicines Agency both catalog these tincture traditions for gout, framing them as historically established but now generally supplanted by safer agents.

A practical traditional recipe, drawn from British pharmacopoeial practice, is a 1:5 tincture. The corm is sliced or powdered and macerated in ethanol (about 45% alcohol by volume), using roughly one part dried corm to five parts solvent, in a dark jar with daily shaking for two weeks before straining. Finish in a dark bottle and store tightly closed. Traditional dosing has been minute and brief, yet colchicine’s narrow therapeutic index means it is unsuitable for self‑medication; avoid during pregnancy and breastfeeding, do not combine with grapefruit juice, and consult a qualified clinician.

Well‑established constituents include colchicine, an aporphine tropolone alkaloid that binds tubulin and is the principal pharmacologically active agent in the corm, alongside colchicine’s oxidative metabolite colchiceine and related tropolone alkaloids such as demecolcine. The presence of colchicine plausibly accounts for the historical gout use.

Modern relevance is limited: because of colchicine’s potent toxicity, commercial preparations of colchicine are strictly regulated, and pharmacognostical work focuses on standardization and safety rather than renewed folk use of the plant.

General Uses Top

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Common products:
Ornamental garden bulbs (corms) are sold in horticultural catalogs for planting in late summer, delivering a profusion of pinkish‑purple flowers in autumn. The species is used in garden borders, rock gardens, and naturalized meadows, providing late‑season color in mixed perennial plantings. Cut flowers are marketed for late‑season floral arrangements.

Industrial and craft applications:
Colchicine, extracted from the corms, is used as a mitotic inhibitor in plant breeding protocols to induce polyploidy. It serves as a standard reagent for chromosome counting and cytogenetic analysis in research labs. Colchicine is employed as a positive control in microtubule polymerization assays and as a reference chemical in assay development. The alkaloid is also used in the preparation of chromosome spreads for microscopic studies. The technique is routinely applied in the breeding of ornamental lilies, tulips, and other geophytes, where chromosome doubling improves flower size and vigor.

Properties relevant to use:
The corms contain approximately 0.2–0.5 % (dry weight) colchicine, a tropolone alkaloid that disrupts microtubule polymerization. This property makes colchicine an effective mitotic arrest agent at concentrations used in laboratory protocols. The alkaloid is stable under acidic extraction conditions, enabling reproducible preparation of stock solutions. The plant’s corms are also rich in storage carbohydrates, which support vegetative propagation but are not utilized commercially due to toxicity. The alkaloid's ability to bind tubulin and inhibit polymerization is well‑characterized, supporting its use in cytogenetics.

Standards and regulation:
Colchicine is classified as a toxic substance under the EU CLP Regulation (EC No 1272/2008) and is subject to mandatory labeling for hazard identification. In the United States, colchicine is listed in the Hazard Communication Standard (29 CFR 1910.1200) and requires Material Safety Data Sheet (MSDS) reporting. The plant itself is treated as a poisonous ornamental in several national plant health regulations, requiring labeling and informing consumers of toxicity. These regulations require that products containing colchicine be packaged with hazard symbols and disposal instructions.

Sustainability and sourcing:
Commercial material is produced mainly by vegetative propagation of cultivated corms, minimizing harvest from wild populations. The species is widespread in Europe and western Asia and is assessed by the IUCN Red List as Least Concern; there are no CITES trade restrictions. Sustainable cultivation practices involve crop rotation and corm division to maintain healthy stock, reducing environmental impact. Seed production is limited and most propagation relies on division of established corm clusters, which can be done annually without depleting the parent stock.

Synonyms Top

Scientific name	Authority	First published in
Bulbocodium antumnale	(L.) Lapeyr.	Civ. Nat. Hist. Jamaica : 202 (1813)
Colchicum autumnale f. macropetala	Gajić	Glasn. Prir. Mus. Beogradu, Ser. B, Biol. Nauke 32: 8 (1977)
Colchicum autumnale f. milosi	Gajić	Glasn. Prir. Mus. Beogradu, Ser. B, Biol. Nauke 32: 8 (1977)
Colchicum autumnale f. radei	Gajić	Glasn. Prir. Mus. Beogradu, Ser. B, Biol. Nauke 32: 8 (1977)
Colchicum borisii	Stef.	Sborn. B'lghar. Akad. Nauk 22: 63 (1926)
Colchicum bulgaricum	Vel.	Oesterr. Bot. Z. 1901: 32 (1901)
Colchicum commune	Neck.	Delic. Gallo-Belg. 1: 176 (1768)
Colchicum crociflorum	Sims	Bot. Mag. 53: t. 2673 (1826)
Colchicum drenowskii	Degen & Rech.f. ex Kitan.	Izv. Bot. Inst. (Sofia) 1: 378 (1950)
Colchicum orientale	Friv. ex Kunth	Enum. Pl. 4: 143 (1843)
Colchicum pannonicum	Griseb. & Schenk	Arch. Naturgesch. 18(1): 359 (1852)
Colchicum polyanthon	Ker Gawl.	Bot. Mag. 26: t. 1028 (1807)
Colchicum praecox	Spenn.	Fl. Friburg. 1: 215 (1825)
Colchicum rhodopaeum	Kovatschev	Novosti Sist. Vyssh. Rast. 2: 87 (1965)
Colchicum transsilvanicum	Schur	Enum. Pl. Transsilv. : 679 (1866)
Colchicum vernale	Hoffm.	Deutschl. Fl. Bot. Taschenb. 3: 174 (1800)
Colchicum vranjanum	Adam.	ex Stefanoff, Monogr. Colch. (Sborn. B'lghar. Akad. Nauk. xxii.) 74 (1926), inobs.
Colchicum autumnale subsp. pannonicum	(Griseb. & Schenk) Nyman	Consp. Fl. Eur. 743. 1882 (1882)
Colchicum autumnale var. elatius	Simonk.	Magyar Bot. Lapok 5: 308. 1906
Colchicum autumnale var. vernale	(Hoffm.) Nyman	Consp. Fl. Eur. 743. 1882
Colchicum autumnale var. transsilvanicum	(Schur) Nyman	Consp. Fl. Eur. 743. 1882
Colchicum turcicum subsp. pannonicum	(Griseb. & Schenk) Nyman	Consp. Fl. Eur. Suppl. 2: 311. 1890 (1890)
Colchicum autumnale var. vernum	Reichard	Syst. Pl. 2: 129. 1779
Colchicum autumnale var. pannonicum	(Griseb. & Schenk) Baker	J. Linn. Soc., Bot. 17: 429. 1879
Colchicum autumnale f. pannonicum	(Griseb. & Schenk) Domin	Magyar Bot. Lapok 8: 330 1909
Colchicum autumnale f. transsilvanicum	(Schur) Domin	Magyar Bot. Lapok 8: 331 1909
Colchicum autumnale f. bulgaricum	(Velen.) Domin	Magyar Bot. Lapok 8: 330 1909
Colchicum autumnale var. bulgaricum	(Velen.) Stoj. & Stef.	Fl. Bulg. 1: 221 1925
Colchicum vernum	(Reichard) Georgi	Beschr. Russ. Reich. 3(4): 923. 1800 (1800)
Colchicum autumnale subsp. vernum	(Reichard) Nyman	Consp. Fl. Eur. 1: 190. 1890 (1890)
Colchicum autumnale var. viridiflorum	Opiz	Seznam 32. 1852
Colchicum autumnale var. speciosissimum	Bubela	Oesterr. Bot. Z. 34: 426. 1884
Colchicum doerfleri var. orientale	Kitanov	Izv. Bot. Inst. (Sofia) 1: 384. 1950
Bulbocodium autumnale	Lapeyr.	Civ. Nat. Hist. Jamaica : 202 (1813)
Colchicum autumnale var. major	Tubergen	Nursery Cat. (van Tubergen) 1897(Bloembollen): 16 (1897)
Colchicum autumnale var. pictum	Lej. & Courtois	Comp. Fl. Belg. 2: 33 (1831)
Colchicum autumnale var. album	Gray	Nat. Arr. Brit. Pl. 2: 173 (1821 publ. 1822)
Colchicum autumnale var. serotinum	Gray	Nat. Arr. Brit. Pl. 2: 173 (1821 publ. 1822)
Colchicum autumnale prol. vernale	(Hoffm.) Rouy	Fl. France 12: 456 (1910)

Common names Top

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Filter by language:

Language	Common/alternative name
English	autumn crocus
English	meadow saffron
English	naked lady
English	naked ladies
Spanish	cebolla montés
Spanish	chicolquicos
Spanish	cholquicos
Spanish	colchico
Spanish	cólchico
Spanish	colchico común
Spanish	cólchico de otoño
Spanish	colchico oficinal
Spanish	colchico que mata
Spanish	cólquico
Spanish	cólquico de otoño
Spanish	despachapastores
Spanish	fell de terra
Spanish	fllo de sementé
Spanish	flor de otoño
Spanish	mataperros
Spanish	narciso de otoño
Spanish	quitameriendas
Spanish	quitameriendas de otoño
Spanish	yerba sembradera
Spanish	matacán
Spanish	azafrán
Spanish	acefrán
Spanish	azafrán bastardo
Spanish	azafrán silvestre
Spanish	acefran
Spanish	cebolla montes
Spanish	colchico de otono
Spanish	cólchico de otono
Spanish	quitameriendas de otono
Amharic	ቡክቡካ
Arabic	سورنجان خريفي
Arabic	لحلاح خريفي
Arabic	سورنجان
Arabic	عكنة
Arabic	خمل
Arabic	اللحلاح
Arabic	خميرة العطار
Azerbaijani	payız vaxtsızçiçəyi
Belarusian	Познацвет асенні
Bulgarian	Есенен минзухар
Bulgarian	Кърпикожух
Bulgarian	Обикновен колхикум
Bulgarian	Обикновен мразовец
Catalan	còlquic
Czech	ocún jesenní
Czech	naháč
Czech	hacoun
Czech	holopanna
Czech	naháček
Czech	sirotka
Welsh	saffrwm y ddôl
Danish	høst-tidløs
German	herbstzeitlose
German	herbst-zeitlose
German	teufelswurz
Greek	Κολχικό το φθινοπωρινό
Esperanto	aŭtuna kolĉiko
Esperanto	aŭtuna kolĥiko
Estonian	harilik sügislill
Basque	azpelar
Persian	زعفران مرغزار
Finnish	alastonimpi
Finnish	syysmyrkkylilja
French	colchique d'automne
French	colchique dautomne
fy	wylde hjerststyleas
Irish	cróch an fhómhair
Galician	cólquico
Galician	tollemerendas
Croatian	mrazovac
Upper Sorbian	jědojty pózdnik
Upper Sorbian	nahula
Upper Sorbian	nazymska pózdnička
Upper Sorbian	nječasnica
Upper Sorbian	pózdnja holčka
Hungarian	Őszi kikerics
Armenian	Շնդեղ աշնանային
Italian	colchino
Italian	colchico autunnale
Japanese	イヌサフラン
Japanese	コルキカム
Japanese	コルチカム
Japanese	コルヒカム
Japanese	コルヒクム
Japanese	コルヒクム子
Japanese	コルヒクム根
ksh	kokokköl
ku	gulemî
Lithuanian	rudeninis vėlyvis
Latvian	rudens vēlziede
Macedonian	Есенски мразовец
Macedonian	мразовец
Norwegian Bokmål	tidlaus
Norwegian Bokmål	tidløs
Dutch	herfststijlloos
Dutch	herfsttijloos
Dutch	wilde herfsttijloos
Norwegian Nynorsk	naken jomfru
Norwegian Nynorsk	tidlaus
Norwegian Nynorsk	tidløyse
Norwegian Nynorsk	hausttidlaus
os	Уазалы малусæг
Polish	zimowit jesienny
Portuguese	açafrão-do-prado
Romanian	brânduşa de toamnă
Romanian	brânduşă de toamnă
Romanian	brândușa de toamnă
Romanian	brândușă de toamnă
Romanian	brînduşă de toamnă
Romanian	brîndușă de toamnă
Russian	Безвременник осенний
Slovak	jesienka obyčajná
Slovenian	jesenski podlesek
Albanian	xherrokulli
Serbian	Мразовац
Swedish	hösttidlösa
Swedish	nakna jungfrun
Swedish	tidlösa
Swedish	vanlig tidlösa
Thai	เมโดว์แซฟฟรอน
Ukrainian	Дикий шафран
Ukrainian	Зимовик
Ukrainian	Морозець
Ukrainian	Пізньоцвіт осінній
Vietnamese	bả chó
Vietnamese	cây bả chó
Walloon	coltchike
Chinese	秋水仙

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Expose seeds to natural outdoor winter conditions for 3 months, then gradually increase light and temperature in the spring.

Sow seeds immediately as their viability decreases rapidly, or they best germinate when fresh. If stored, seeds might need temperature cycling and patience to germinate.

must have summer heat to germinate; may take 6 years to germinate; grow seedlings @ 4°C x 1 month

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Australasia click to expand
- New Zealand
  - New Zealand South

Europe click to expand
- Eastern Europe
  - Baltic States
  - Northwest European Russia
  - Ukraine
- Middle Europe
  - Austria
  - Belgium
  - Czechoslovakia
  - Germany
  - Hungary
  - Netherlands
  - Poland
  - Switzerland
- Northern Europe
  - Denmark
  - Great Britain
  - Ireland
  - Sweden
- Southeastern Europe
  - Albania
  - Bulgaria
  - Greece
  - Italy
  - Romania
  - Yugoslavia
- Southwestern Europe
  - France
  - Spain

Northern America click to expand
- Northeastern U.S.A.
  - New Hampshire
  - Vermont
- Northwestern U.S.A.
  - Oregon
- Southeastern U.S.A.
  - Kentucky
  - North Carolina
- Southwestern U.S.A.
  - Utah

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000763824
UNII	W79255C628
USDA Plants	COAU4
Tropicos	18401617
INPN	92127
Flora of Italy	6764
KEW	urn:lsid:ipni.org:names:533232-1
The Plant List	kew-302771
Missouri Botanical Garden	282050
PFAF	Colchicum autumnale
Open Tree Of Life	295700
Observations.org	2449
NCBI Taxonomy	45005
NBN Atlas	NBNSYS0000002189
Nature Serve	2.152811
IUCN Red List	202977
IPNI	533232-1
iNaturalist	131586
GBIF	2739622
Freebase	/m/02ywc7
EPPO	CXHAU
EOL	1086971
Elurikkus	3877
US Library of Congress	sh2007006056
USDA GRIN	11137
Wikipedia	Colchicum_autumnale

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

The role of colchicine in the management of COVID-19: a Meta-analysis

Elshiwy K, Amin GE, Farres MN, Samir R, Allam MF

BMC Pulm Med

20-Apr-2024

PMCID:	PMC11031948
doi:	10.1186/s12890-024-03001-0
PMID:	38641775

Investigating efficacy of colchicine plus phenolic monoterpenes fraction as a potential treatment for patients diagnosed with COVID-19: A randomized controlled parallel clinical trial

Vaziri S, Janbakhsh A, Zamanian MH, Shakiba Y, Mostafaei S, Norooznezhad AH, Mansouri K, Bagheri A, Abdali F, Fatahpour K, Mostafaie A

Heliyon

06-Mar-2024

PMCID:	PMC10955262
doi:	10.1016/j.heliyon.2024.e27373
PMID:	38515718

Microtubule destabilization with colchicine increases the work output of myocardial slices

Hancock EN, Palmer BM, Caporizzo MA

J Mol Cell Cardiol Plus

29-Feb-2024

PMCID:	PMC10997380
doi:	10.1016/j.jmccpl.2024.100066
PMID:	38584975

Natural products in osteoarthritis treatment: bridging basic research to clinical applications

Fang S, Zhang B, Xiang W, Zheng L, Wang X, Li S, Zhang T, Feng D, Gong Y, Wu J, Yuan J, Wu Y, Zhu Y, Liu E, Ni Z

Chin Med

15-Feb-2024

PMCID:	PMC10870578
doi:	10.1186/s13020-024-00899-w
PMID:	38360724

PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin

Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF

J Med Chem

31-Jan-2024

PMCID:	PMC10895673
doi:	10.1021/acs.jmedchem.3c01775
PMID:	38294341

An Unusual Cause of Longstanding Diarrhea

Peralta I, Hubbard E, Nodit L

Cureus

12-Jan-2024

PMCID:	PMC10859108
doi:	10.7759/cureus.52161
PMID:	38344513

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity

Huang R, Duan J, Huang W, Cheng Y, Zhu B, Li F

Toxins (Basel)

09-Jan-2024

PMCID:	PMC10818746
doi:	10.3390/toxins16010035
PMID:	38251251

Platelets promote human macrophages-mediated macropinocytosis of Clostridioides difficile

Barbero AM, Hernández Del Pino RE, Fuentes F, Barrionuevo P, Pasquinelli V

Front Cell Infect Microbiol

05-Jan-2024

PMCID:	PMC10796631
doi:	10.3389/fcimb.2023.1252509
PMID:	38249298

Genomic and Cytogenetic Analysis of Synthetic Polyploids between Diploid and Tetraploid Cotton (Gossypium) Species

Khidirov MT, Ernazarova DK, Rafieva FU, Ernazarova ZA, Toshpulatov AK, Umarov RF, Kholova MD, Oripova BB, Kudratova MK, Gapparov BM, Khidirova MM, Komilov DJ, Turaev OS, Udall JA, Yu JZ, Kushanov FN

Plants (Basel)

17-Dec-2023

PMCID:	PMC10748080
doi:	10.3390/plants12244184
PMID:	38140511

Do Poisonous Plants in Pastures Communicate Their Toxicity? Meta-Study and Evaluation of Poisoning Cases in Central Europe

Aboling S

Animals (Basel)

08-Dec-2023

PMCID:	PMC10740430
doi:	10.3390/ani13243795
PMID:	38136831

Colchicine: the good, the bad, the ugly and how to minimize the risks

Stamp LK, Horsley C, Te Karu L, Dalbeth N, Barclay M

Rheumatology (Oxford)

29-Nov-2023

PMCID:	PMC10986813
doi:	10.1093/rheumatology/kead625
PMID:	38019947

Which Plant Species for Green Roofs in the Mediterranean Environment?

Leotta L, Toscano S, Romano D

Plants (Basel)

27-Nov-2023

PMCID:	PMC10708222
doi:	10.3390/plants12233985
PMID:	38068621

Clinical Approach to Post-acute Sequelae After COVID-19 Infection and Vaccination

Hulscher N, Procter BC, Wynn C, McCullough PA

Cureus

21-Nov-2023

PMCID:	PMC10663976
doi:	10.7759/cureus.49204
PMID:	38024037

Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels

Veiga-Matos J, Morales AI, Prieto M, Remião F, Silva R

Molecules

10-Nov-2023

PMCID:	PMC10673607
doi:	10.3390/molecules28227532
PMID:	38005253

Expositionen mit Fruchtpflanzen in Deutschland im Zeitraum 2010–2019: Auswertung der Datenbank des Gemeinsamen Giftinformationszentrums Erfurt (GGIZ)

Wendt S, Prasa D, Lübbert C, Begemann K, Franke H

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz

12-Oct-2023

PMCID:	PMC10667429
doi:	10.1007/s00103-023-03780-7
PMID:	37828294

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / Androcymbine alkaloids
Isoandrocymbine	46173814	Click to see CN1CCC23C=C(C(=O)C=C2C1CCC4=CC(=C(C(=C34)OC)OC)O)OC	371.40	unknown	https://doi.org/10.1016/S0040-4039(97)10011-9
> Alkaloids and derivatives / Lumicolchicine alkaloids
Acetamide,N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]-	6713941	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=C1C4C3C=C(C4=O)OC)OC)OC)OC	399.40	unknown	https://doi.org/10.1135/CCCC19540805 https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1300/J044V09N01_08
beta-Lumicolchicine	244898	Click to see	399.40	unknown	https://doi.org/10.1002/PCA.702 https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1002/HLCA.19500330629
gamma-Lumicolchicine	110937	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=C1C4C3C=C(C4=O)OC)OC)OC)OC	399.40	unknown	https://doi.org/10.1002/HLCA.19500330629 https://doi.org/10.1135/CCCC19540805 https://doi.org/10.1135/CCCC19500552
N-(4-hydroxy-3,5,14-trimethoxy-13-oxo-10-tetracyclo[9.5.0.02,7.012,16]hexadeca-1(11),2,4,6,14-pentaenyl)acetamide	73834247	Click to see	385.40	unknown	https://doi.org/10.1002/HLCA.19500330629
N-[(10S,12R,16S)-4-hydroxy-3,5,14-trimethoxy-13-oxo-10-tetracyclo[9.5.0.02,7.012,16]hexadeca-1(11),2,4,6,14-pentaenyl]acetamide	21769953	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=C1C4C3C=C(C4=O)OC)OC)O)OC	385.40	unknown	https://doi.org/10.1002/HLCA.19500330629
N-methyl-N-[(10S,12S,16R)-3,5,14-trimethoxy-13-oxo-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-10-tetracyclo[9.5.0.02,7.012,16]hexadeca-1(11),2,4,6,14-pentaenyl]acetamide	162877239	Click to see	561.60	unknown	https://doi.org/10.1135/CCCC19540805
N-methyl-N-[3,5,14-trimethoxy-13-oxo-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-10-tetracyclo[9.5.0.02,7.012,16]hexadeca-1(11),2,4,6,14-pentaenyl]acetamide	162877238	Click to see CC(=O)N(C)C1CCC2=CC(=C(C(=C2C3=C1C4C3C=C(C4=O)OC)OC)OC5C(C(C(C(O5)CO)O)O)O)OC	561.60	unknown	https://doi.org/10.1135/CCCC19540805
> Alkaloids and derivatives / Phenethylisoquinoline alkaloids
(1S)-1,2,3,4-Tetrahydro-1-(2-(3-hydroxy-4,5-dimethoxyphenyl)ethyl)-6-methoxy-2-methyl-7-isoquinolinol	13878324	Click to see	373.40	unknown	https://doi.org/10.1039/A803853H https://doi.org/10.1016/S0040-4039(97)10011-9
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Benzamides
Benzamide	2331	Click to see	121.14	unknown	https://doi.org/10.1055/S-0028-1097251
> Hydrocarbon derivatives / Tropones
(7R)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one	638269	Click to see CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC	371.40	unknown	https://doi.org/10.1055/S-0028-1097251
(7R)-2-hydroxy-1,3,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one	162981501	Click to see	357.40	unknown	https://doi.org/10.1055/S-0028-1097251
(7S)-3-hydroxy-1,2,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one	14413737	Click to see	357.40	unknown	https://doi.org/10.1055/S-0028-1097251
[2-[(2-acetyloxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)amino]-2-oxoethyl] acetate	162892290	Click to see	485.50	unknown	https://doi.org/10.3987/R-1979-03-0337
[2-[[(7S)-2-acetyloxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]amino]-2-oxoethyl] acetate	162892291	Click to see	485.50	unknown	https://doi.org/10.3987/R-1979-03-0337
1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo(a)heptalen-9-one	2832	Click to see	371.40	unknown	https://doi.org/10.1039/A803851A https://doi.org/10.1135/CCCC19540141 https://doi.org/10.1271/BBB1961.52.593 https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1055/S-0028-1097251
2-Demthyldemecolcine	146030	Click to see	357.40	unknown	https://doi.org/10.1135/CCCC19540141 https://doi.org/10.1135/CCCC19540805
2-hydroxy-1,3,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one	14413735	Click to see	357.40	unknown	https://doi.org/10.1135/CCCC19540805 https://doi.org/10.1135/CCCC19540141 https://doi.org/10.1055/S-0028-1097251
3-[[(4-Cyclopentyl-1-piperazinyl)-imino]methyl]rifamycin	5030992	Click to see COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC=O	385.40	unknown	https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1135/CCCC19540805 https://doi.org/10.1055/S-0028-1097251 https://doi.org/10.1002/HLCA.19500330629
3-Demethylcolchicine	299664	Click to see	385.40	unknown	https://doi.org/10.1135/CCCC19540141 https://doi.org/10.1002/PCA.702 https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1135/CCCC19832989 https://doi.org/10.1002/HLCA.19500330629
3-hydroxy-1,2,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one	14413736	Click to see CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)O	357.40	unknown	https://doi.org/10.1055/S-0028-1097251
Acetamide, N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-	541033	Click to see	385.40	unknown	https://doi.org/10.1055/S-0028-1097251
Colchicine	6167	Click to see	399.40	unknown	https://doi.org/10.1016/0031-9422(88)80197-3 https://doi.org/10.1016/0031-9422(88)80196-1 https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1039/A803851A https://doi.org/10.1002/PCA.702 https://doi.org/10.1016/S0031-9422(97)00242-2 https://doi.org/10.1039/A803852J https://doi.org/10.1039/P19830003053 https://doi.org/10.1016/S0040-4039(97)10011-9 https://doi.org/10.1039/A803853H https://doi.org/10.1271/BBB1961.52.593 https://doi.org/10.1039/A803850C https://doi.org/10.1016/S0040-4020(01)87895-9
Colchicine, (+)-	53278	Click to see	399.40	unknown	https://doi.org/10.1055/S-0028-1097251
Demecolcine	220401	Click to see CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC	371.40	unknown	https://doi.org/10.1039/A803851A https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1271/BBB1961.52.593 https://doi.org/10.1135/CCCC19540141
N-(2-hydroxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)formamide	162905149	Click to see	371.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide	494161	Click to see	385.40	unknown	https://doi.org/10.1135/CCCC19540141 https://doi.org/10.1055/S-0028-1097251 https://doi.org/10.1002/HLCA.19500330629
N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)formamide	301815	Click to see	371.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide	2833	Click to see	399.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide	92149270	Click to see	385.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-[(7R)-2-hydroxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide	92165697	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)OC	385.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-[(7R)-3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide	92142360	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)O	385.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-[(7R)-3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide	163003027	Click to see COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)O)NC=O	371.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-Deacetyl-N-formyl-2-demethylcolchicine	101648678	Click to see COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)O)OC)NC=O	371.40	unknown	https://doi.org/10.1055/S-0028-1097251
N-deacetyl-N-formylcolchicine	23890	Click to see	385.40	unknown	https://doi.org/10.1135/CCCC19500552 https://doi.org/10.1135/CCCC19540805 https://doi.org/10.1002/HLCA.19500330629
N-Methyl-N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)formamide	26819	Click to see	399.40	unknown	https://doi.org/10.1039/A803852J
> Hydrocarbon derivatives / Tropones / Tropolones
7-Acetamido-10-hydroxy-1,2,3-trimethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one	10156	Click to see	385.40	unknown	https://doi.org/10.1135/CCCC19540805
Colchiceine	234105	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC	385.40	unknown	https://doi.org/10.1135/CCCC19540805
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
CID 24721008	24721008	Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC4C(C(C(C(O4)CO)O)O)O	547.50	unknown	https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1271/BBB1961.52.593
Colchicoside	92763	Click to see	547.50	unknown	https://doi.org/10.1300/J044V09N01_08 https://doi.org/10.1002/PCA.702
N-[(7R)-1,2,10-trimethoxy-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide	162982646	Click to see	547.50	unknown	https://doi.org/10.1080/00021369.1988.10868674
N-[1,2,10-trimethoxy-9-oxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide	233866	Click to see	547.50	unknown	https://doi.org/10.1271/BBB1961.52.593 https://doi.org/10.1080/00021369.1988.10868674 https://doi.org/10.1002/PCA.702
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Apigenin	5280443	Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O	270.24	unknown	https://doi.org/10.1135/CCCC19540805

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Colchicum autumnale

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