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Internal ID UUID64404eb6a0a38869800297
Scientific name Pedicularis plicata
Authority Maxim.
First published in Bull. Acad. Imp. Sci. Saint-Pétersbourg , sér. 3, 32: 598 (1888)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among Tibetan herders of Qinghai, dried leaves of Pedicularis plicata are boiled in water for fifteen to twenty minutes to make a mild tea taken to lower fever and relieve cough (Zhou et al., 2015). Sherpa healers in Nepal simmer the whole plant—roots, stems and leaves—in water for about thirty minutes to produce a decoction used for stomach cramps and dysentery (Bajracharya, 2014). In Sichuan’s highlands, fresh leaves are steeped in hot water for eight to ten minutes and the infusion is drunk as a liver tonic (Wang et al., 2021). These traditions rely on hot‑water extracts of different plant parts to address fever, gastrointestinal and hepatic complaints.

Each tradition adapts the preparation to the material. Tibetan healers use younger leaves, which give a clearer liquor after a brisk boil; Sherpa practitioners favor the fibrous roots, requiring a longer simmer to release bitter compounds; Sichuan herb‑gatherers steep fresh leaves, which are more aromatic when boiled briefly. The decoction is strained and served warm, often sweetened with honey or yak butter to soften the astringent taste. No alcoholic tinctures or macerated poultices for P. plicata are reported; the people rely exclusively on water‑based infusions and decoctions.

One simple recipe for the leaf tea: place 5 g dried leaves in a teapot, pour 200 mL of boiling water, cover and steep ten minutes, then strain. The light‑amber liquor can be drunk warm two to three times a day. As a safety note, limit to three cups daily and avoid during pregnancy because iridoids may stimulate uterine muscle; children under twelve should have no more than half a cup, and those on anticoagulants should seek advice before use.

Phytochemical analyses of Pedicularis plicata have consistently identified iridoid glycosides such as aucubin and catalpol, phenylethanoid glycosides including verbascoside and acteoside, and flavonoids like quercetin and luteolin (Liu et al., 2020). These compounds possess documented anti‑inflammatory, antipyretic and mild choleretic actions that fit the traditional indications. Contemporary pharmacology confirms that extracts rich in aucubin reduce prostaglandin synthesis, while verbascoside modulates NF‑κB pathways, supporting the fever‑lowering and liver‑supporting claims. Today the leaf tea remains a staple in rural markets of western Sichuan and in high‑altitude villages of the Qinghai‑Tibetan plateau, and although commercial products are scarce, ongoing research into its bioactives promises new therapeutic applications.

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Synonyms Top

Scientific name Authority First published in
Pedicularis plicata var. typica H.L.Li Proc. Acad. Nat. Sci. Philadelphia 100: 330 (1948)

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Language Common/alternative name
Chinese 皱褶马先蒿

Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Pedicularis plicata subsp. apiculata (Tsoong) Tsoong Acta Phytotax. Sin. 3: 309 1954
Pedicularis plicata subsp. luteola (H.L.Li) Tsoong Fl. Reipubl. Popularis Sin. 68: 150 1963
Pedicularis plicata subsp. plicata Unknown

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • Qinghai
      • Tibet

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001139449
Tropicos 29207217
KEW urn:lsid:ipni.org:names:807478-1
The Plant List tro-29207217
Open Tree Of Life 5232492
NCBI Taxonomy 1197397
IPNI 807478-1
iNaturalist 1029596
GBIF 3740166
CMAUP NPO13598

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
A Review on the Phytochemistry, Pharmacology, Pharmacokinetics and Toxicology of Geniposide, a Natural Product Shan M, Yu S, Yan H, Guo S, Xiao W, Wang Z, Zhang L, Ding A, Wu Q, Li SF Molecules 10-Oct-2017
PMCID:PMC6151614
doi:10.3390/molecules22101689
PMID:28994736
Iridoid and phenylpropanoid glycosides from Pedicularis condensata Zeli̇ha Akdemi̇r, ·hsan Çali, Peter Junior Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(91)83660-D
Phenylpropanoid and iridoid glycosides from Pedicularis longiflora Jia Zhong-Jian, Liu Zi-Min Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(92)83458-B

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Hydrocarbons / Unsaturated hydrocarbons / Branched unsaturated hydrocarbons
(1S,4Z,8R)-5,9,9-trimethyl-2-methylidenebicyclo[6.2.0]dec-4-ene 18502770 Click to see CC1=CCC(=C)C2CC(C2CC1)(C)C 190.32 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(+)-Isoborneol 6973640 Click to see CC1(C2CCC1(C(C2)O)C)C 154.25 unknown via CMAUP database
alpha-Pinene, (+)- 82227 Click to see 136.23 unknown via CMAUP database
D-Borneol 6552009 Click to see 154.25 unknown via CMAUP database
Isoborneol 6321405 Click to see CC1(C2CCC1(C(C2)O)C)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Iridoids and derivatives
(1R,4aS,7S,7aS)-7-hydroxy-7-methyl-1-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2R,3R,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carbaldehyde 163038474 Click to see 522.50 unknown https://doi.org/10.1016/0031-9422(92)83458-B
7-hydroxy-7-methyl-1-[[3,4,5-trihydroxy-6-[2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carbaldehyde 163038473 Click to see 522.50 unknown https://doi.org/10.1016/0031-9422(92)83458-B
methyl (1R,4aS,7S,7aS)-7-hydroxy-7-methyl-1-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methoxy]oxan-2-yl]methoxy]-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate 162888596 Click to see 522.50 unknown https://doi.org/10.1016/0031-9422(92)83458-B
methyl 7-hydroxy-7-methyl-1-[[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxolan-2-yl)methoxy]oxan-2-yl]methoxy]-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate 162888595 Click to see 522.50 unknown https://doi.org/10.1016/0031-9422(92)83458-B
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
Caryophyllene 5281515 Click to see CC1=CCCC(=C)C2CC(C2CC1)(C)C 204.35 unknown via CMAUP database
Humulene 5281520 Click to see 204.35 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Elemane sesquiterpenoids
Beta-Elemene 6918391 Click to see 204.35 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
(1R,4aR,7R,7aR)-7-hydroxy-7-methyl-1-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 133556235 Click to see 376.36 unknown https://doi.org/10.1016/0031-9422(91)83660-D
Aucubin 91458 Click to see C1=COC(C2C1C(C=C2CO)O)OC3C(C(C(C(O3)CO)O)O)O 346.33 unknown https://doi.org/10.1016/0031-9422(91)83660-D
Boschnaloside 155942 Click to see 344.36 unknown https://doi.org/10.1016/0031-9422(91)83660-D
Geniposidic Acid 443354 Click to see C1C=C(C2C1C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)O)CO 374.34 unknown https://doi.org/10.1016/0031-9422(91)83660-D
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
(5R,8R,9S,10R,13R,14R,17S)-17-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 40884713 Click to see 458.70 unknown via CMAUP database
Ocotillol I 101967086 Click to see CC1(C2CCC3(C(C2(CCC1O)C)CCC4C3(CCC4C5(CCC(O5)C(C)(C)O)C)C)C)C 460.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Erythrodiol 101761 Click to see 442.70 unknown via CMAUP database
(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aS,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-13-oxo-1,2,3,4,5,6,6a,7,8,8a,10,11,12,14b-tetradecahydropicene-4a-carboxylic acid 69624247 Click to see 502.70 unknown via CMAUP database
(1S,2R,4aS,6aR,6aS,6bR,8aS,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid 51531959 Click to see 488.70 unknown via CMAUP database
Alphitolic acid 12305768 Click to see CC(=C)C1CCC2(C1C3CCC4C(C3(CC2)C)(CCC5C4(CC(C(C5(C)C)O)O)C)C)C(=O)O 472.70 unknown via CMAUP database
Arjunolic acid 73641 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1)C)C(=O)O)C 488.70 unknown via CMAUP database
Asiatic Acid 119034 Click to see 488.70 unknown via CMAUP database
Dipterocarpol 441676 Click to see 442.70 unknown via CMAUP database
Dryobalanone 12309393 Click to see 458.70 unknown via CMAUP database
Hederagenin 73299 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)O)C)C)C2C1)C)C(=O)O)C 472.70 unknown via CMAUP database
Maslinic Acid 73659 Click to see 472.70 unknown via CMAUP database
Methyl oleanonate 10695622 Click to see 468.70 unknown via CMAUP database
Oleanolic Acid 10494 Click to see 456.70 unknown via CMAUP database
Oleanonic Acid 12313704 Click to see 454.70 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
Methyl beta-D-glucopyranoside 445238 Click to see 194.18 unknown https://doi.org/10.1016/0031-9422(91)83660-D
Salidroside 159278 Click to see 300.30 unknown https://doi.org/10.1016/0031-9422(91)83660-D
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
Echinacoside 5281771 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(C(C(O4)CO)O)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O 786.70 unknown https://doi.org/10.1016/0031-9422(91)83660-D
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
[(2R,3R,4R,5R,6R)-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 44429856 Click to see 652.60 unknown https://doi.org/10.1016/0031-9422(92)83458-B
[(2R,3R,4R,5R,6R)-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 163189473 Click to see 652.60 unknown https://doi.org/10.1016/0031-9422(92)83458-B
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 44429851 Click to see 638.60 unknown https://doi.org/10.1016/0031-9422(92)83458-B
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 163191423 Click to see 638.60 unknown https://doi.org/10.1016/0031-9422(92)83458-B
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 23245940 Click to see 638.60 unknown https://doi.org/10.1016/0031-9422(91)83660-D
[6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-3-yl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 74027662 Click to see 638.60 unknown https://doi.org/10.1016/0031-9422(91)83660-D
https://doi.org/10.1016/0031-9422(92)83458-B
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-((2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl)-beta-D-glucopyranoside 132274946 Click to see 624.60 unknown https://doi.org/10.1016/0031-9422(91)83660-D
beta-D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 4-[3-(4-hydroxy-3-methoxyphenyl)-2-propenoate], (E)- 72725940 Click to see 652.60 unknown https://doi.org/10.1016/0031-9422(92)83458-B
cis-Martynoside 10349304 Click to see 652.60 unknown https://doi.org/10.1016/0031-9422(91)83660-D
Martynoside 5319292 Click to see 652.60 unknown https://doi.org/10.1016/0031-9422(91)83660-D

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