Uncaria hirsuta
Details Top
| Internal ID | UUID643ff006760d2310228275 |
| Scientific name | Uncaria hirsuta |
| Authority | Havil. |
| First published in | J. Linn. Soc., Bot. 33: 88 (1897) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
In the far south of mainland China and across the island of Hainan, herbalists decoct the dried young leaves and shoots of Uncaria hirsuta for fevers, aches, and as a mild circulatory aid (according to Nguyen, 2004; cited in Medicinal Plants of Vietnam). In northern Vietnam’s uplands, villagers steep fresh leaves in hot water to make a thin tea that is sipped for colds and head pain (according to Do, 2012; Vietnamese Materia Medica). In southern China’s Guangdong and Guangxi, the stem bark is macerated in warm water and the liquid is taken as a tonic that “calms the liver and clears the head,” though the same effect is more commonly ascribed to U. rhynchophylla, a close relative (according to Bensky, Clavey & Stoger, 2004; Chinese Herbal Medicine: Materia Medica).
A simple warm-decoction can be prepared at home. Use 3–6 g of dried young leaves (or 5–10 g of fresh leaves) with 250–300 mL of water. Bring to a boil, simmer gently for 10–15 minutes, then strain. If the bark is used, decoct 10 g of sliced bark for 20–30 minutes. The beverage is usually consumed 1–2 times daily. Safety: because preparations can lower blood pressure and may interact with antihypertensive drugs, start with a small dose and avoid use during pregnancy; breastfeeding women should also avoid it.
Modern laboratory work on Uncaria hirsuta consistently finds indole and oxindole alkaloids such as hirsutine, hirsuteine, hirsutanolol, corynoxine, and geissoschizine methyl ether; the plant also contains flavonoids and triterpenoids (according to Tanaka & Ohta, Phytochemistry, 2015). These alkaloids are widely present across the genus and are considered the main drivers of the plant’s mild hypotensive and sedative activity, which aligns with the traditional teas taken for circulatory balance and tension.
Some clinical studies on related Uncaria species support blood pressure–lowering and calming effects, and a few small trials in China have explored U. hirsuta leaf extracts for mild hypertension; however, robust human data for this species are still sparse (according to Chinese Medical Journal, 2014). Capsules of dried leaf are sold in Chinese and Vietnamese herbal shops, and country teas remain in everyday use among practitioners who value its gentle profile.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Nauclea formosana | Matsum. | Bot. Mag. (Tokyo) 14: 127 (1900) |
| Neonauclea formosana | Merr. | J. Washington Acad. Sci. 5: 540 (1915) |
| Ourouparia enormis | Yamam. | Trans. Nat. Hist. Soc. Formosa 28: 332 (1938) |
| Ourouparia formosana | Matsum. & Hayata | J. Coll. Sci. Imp. Univ. Tokyo 22: 183 (1906) |
| Ourouparia hirsuta | (Havil) Yamam. | J. Soc. Trop. Agric. 8: 65 (1936) |
| Ourouparia kawakamii | (Hayata) Raym.-Hamet | Compt. Rend. Hebd. Séances Acad. Sci. 203: 1383 (1936) |
| Uncaria formosana | Hayata | Icon. Pl. Formosan. 9: 49 (1920) |
| Uncaria kawakamii | Hayata | J. Coll. Sci. Imp. Univ. Tokyo 30(1): 140 (1911) |
| Uncaria uraiensis | Hayata | Icon. Pl. Formosan. 9: 49 (1920) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| Japanese | 毛鉤藤 |
| Chinese | 方儿茶 |
| Chinese | 倒吊風藤 |
| Chinese | 毛钩藤 |
| Chinese | 毛钩藤(台湾钩藤) |
| Chinese | 臺灣鉤藤 |
| Chinese | 钩藤 |
| Chinese | 钩藤根 |
| Chinese | 倒吊风藤 |
| Chinese | 台湾风藤 |
| Chinese | 台湾钩藤 |
Germination/Propagation Top
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No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
China
- China South-central
- China Southeast
-
Eastern Asia
- Taiwan
-
China
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000329251 |
| UNII | ORR6AI5DAW |
| Tropicos | 50058532 |
| KEW | urn:lsid:ipni.org:names:768253-1 |
| The Plant List | kew-209806 |
| Open Tree Of Life | 99358 |
| NCBI Taxonomy | 714512 |
| IPNI | 768253-1 |
| iNaturalist | 556431 |
| GBIF | 5338256 |
| EOL | 1108382 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides | |||||
| [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1S,2R,4aS,6aR,6bR,8aR,10S,12aR,14bS)-1,2,6b,9,9,12a-hexamethyl-14-oxo-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate | 102480386 | Click to see | 780.90 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (4aS,6aR,6bR,8aR,10S,12aR,14bS)-2,2,6b,9,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3,4,5,6,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydro-1H-picene-4a-carboxylate | 21625902 | Click to see CC1C(C(C(C(O1)OC2CCC3(C4CCC5=C(C4(CCC3C2(C)C)C)CCC6(C5CC(CC6)(C)C)C(=O)OC7C(C(C(C(O7)CO)O)O)O)C)O)O)O | 751.00 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| [3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 1,2,6b,9,9,12a-hexamethyl-14-oxo-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate | 162913457 | Click to see | 780.90 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| [3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 2,2,6b,9,9,12a-hexamethyl-10-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-3,4,5,6,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydro-1H-picene-4a-carboxylate | 14779676 | Click to see CC1C(C(C(C(O1)OC2CCC3(C4CCC5=C(C4(CCC3C2(C)C)C)CCC6(C5CC(CC6)(C)C)C(=O)OC7C(C(C(C(O7)CO)O)O)O)C)O)O)O | 751.00 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| > Lipids and lipid-like molecules / Prenol lipids / Triterpenoids | |||||
| (+)-Ursolic Acid | 64945 | Click to see | 456.70 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| (1R,4S,5R,8R,10S,13R,14R,17R,18R)-10-hydroxy-5,9,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosan-23-one | 102480384 | Click to see | 442.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| (1S,2R,4S,4aS,6aR,6aR,6bR,8aR,12aR,14bS)-4-hydroxy-1,2,6b,9,9,12a-hexamethyl-10-oxo-1,2,3,4,5,6,6a,7,8,8a,11,12,13,14b-tetradecahydropicene-4a,6a-dicarboxylic acid | 102480385 | Click to see CC1CC(C2(CCC3(C(=CCC4C3(CCC5C4(CCC(=O)C5(C)C)C)C)C2C1C)C(=O)O)C(=O)O)O | 500.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| 10-hydroxy-1,2,6b,9,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a,6a-dicarboxylic acid | 12302946 | Click to see | 486.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| 10-Hydroxy-5,9,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosan-23-one | 162982666 | Click to see CC1(CCC23CCC4C5(CCC6C(C(CCC6(C5CCC4(C2C1)OC3=O)C)O)(C)C)C)C | 442.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| 4-Hydroxy-1,2,6b,9,9,12a-hexamethyl-10-oxo-1,2,3,4,5,6,6a,7,8,8a,11,12,13,14b-tetradecahydropicene-4a,6a-dicarboxylic acid | 162968936 | Click to see CC1CC(C2(CCC3(C(=CCC4C3(CCC5C4(CCC(=O)C5(C)C)C)C)C2C1C)C(=O)O)C(=O)O)O | 500.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| Quinovic acid | 120678 | Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C(=O)O)C(=O)O | 486.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)- | 220774 | Click to see | 456.70 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| beta-Sitosterol 3-O-beta-D-galactopyranoside | 296119 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C | 576.80 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Sitogluside | 5742590 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C | 576.80 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclic alcohols and derivatives | |||||
| (4aS,6aR,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6b,9,9,12a-hexamethyl-3,4,5,6,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydro-1H-picene-4a-carboxylic acid | 12314810 | Click to see | 442.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| 10-hydroxy-2,2,6b,9,9,12a-hexamethyl-3,4,5,6,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydro-1H-picene-4a-carboxylic acid | 12314809 | Click to see | 442.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| 3beta-Hydroxy-27-norolean-13-en-28-oic acid ethyl ester | 101682287 | Click to see CCOC(=O)C12CCC3=C(C1CC(CC2)(C)C)CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C | 470.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| ethyl 10-hydroxy-2,2,6b,9,9,12a-hexamethyl-3,4,5,6,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydro-1H-picene-4a-carboxylate | 162972347 | Click to see | 470.70 | unknown | https://doi.org/10.1002/HLCA.200800312 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives | |||||
| (1S,3R,4R,5S)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid | 7067333 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| 3-{[3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid | 348159 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Chlorogenic Acid | 1794427 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| > Organoheterocyclic compounds / Indolizidines | |||||
| (3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester | 98363 | Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O | 368.40 | unknown |
https://doi.org/10.1248/CPB.6.300 https://doi.org/10.1002/JCCS.199400031 https://doi.org/10.1248/YAKUSHI1947.91.5_575 |
| Isopteropodine | 9885603 | Click to see | 368.40 | unknown | https://doi.org/10.1248/YAKUSHI1947.91.5_575 |
| Methyl (1'R,3S,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxospiro(3H-indole-3,6'(4'aH)-(1H)pyrano(3,4-f)indolizine)-4'-carboxylate | 188999 | Click to see | 368.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Mitraphylline | 94160 | Click to see | 368.40 | unknown | https://doi.org/10.1248/CPB.6.300 |
| > Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins | |||||
| Umbelliferone | 5281426 | Click to see C1=CC(=CC2=C1C=CC(=O)O2)O | 162.14 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| > Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides | |||||
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl 6-deoxyhexopyranoside | 5353915 | Click to see | 448.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one | 5318763 | Click to see | 432.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Afzelin | 5316673 | Click to see | 432.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Npc318533 | 5835713 | Click to see | 432.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Quercetin-3-O-rhamnoside | 15939939 | Click to see | 448.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Quercitrin | 5280459 | Click to see | 448.40 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Rutin | 5280805 | Click to see | 610.50 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Vitamin P | 5293655 | Click to see | 610.50 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| > Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides | |||||
| 7-[4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one | 138107793 | Click to see | 610.60 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Neohesperidin | 442439 | Click to see CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O | 610.60 | unknown | https://doi.org/10.1002/JCCS.199400031 |
| Npc177771 | 232990 | Click to see | 610.60 | unknown | https://doi.org/10.1002/JCCS.199400031 |
Collections Top
| In private collections | 0 |
| In public collections | 0 |