Mitragyna speciosa

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Synonyms

Common Names

Subtypes (subspecies, varieties, subvarieties, forms)

Germination/Propagation

Distribution

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Genome

Scientific Literature

Phytochemical Profile

Biological Material

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Details Top

Internal ID	UUID643fe38f8b28e498980542
Scientific name	Mitragyna speciosa
Authority	Korth.
First published in	Verh. Nat. Gesch. Ned. Bezitt., Bot. : t. 35 (1841)

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Synonyms Top

Scientific name	Authority	First published in
Nauclea luzoniensis	Blanco	Fl. Filip., ed. 2 : 102 (1845)
Nauclea speciosa	Miq.	Fl. Ned. Ind. 2: 140 (1856)
Stephegyne speciosa	Korth.	Verh. Nat. Gesch. Ned. Bezitt., Bot. : 160 (1842)

Common names Top

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Filter by language:

Language	Common/alternative name
English	kratom
Spanish	kratom
ace	biek
Arabic	قرطوم
Bulgarian	кратом
bjn	sapat
Czech	kratom
German	kratombaum
German	kratom
Greek	Κρατόμ
Esperanto	kratomo
Persian	میتراگینا اسپکیوسا
Finnish	kratom
Finnish	siaminkratomi
French	kratom
Croatian	kratom
Indonesian	kratom
Italian	kratom
Japanese	アヘンボク
Japanese	クラトム
Japanese	クラトーム
mnw	ကြဓေါမ်၊ တၞံ
Malay	pokok ketum
Burmese	ဘိန်းစာပင်
Norwegian Bokmål	kratom
Dutch	kratom
Polish	kratom
Portuguese	kratom
Romanian	kratom
Russian	Кратом
Slovenian	kratom
su	kratom
su	ki hanja
Swedish	kratom
Swahili	kratom
Thai	ใบกระท่อม
Thai	พืชกระท่อม
Thai	กระท่อม
Vietnamese	kratom
Chinese	哥冬
Chinese	卡痛

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Asia-tropical click to expand
- Indo-China
  - Cambodia
  - Thailand
  - Vietnam
- Malesia
  - Borneo
  - Malaya
  - Philippines
  - Sumatera
- Papuasia
  - New Guinea

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000244943
Tropicos	100225434
KEW	urn:lsid:ipni.org:names:756303-1
The Plant List	kew-128805
Open Tree Of Life	223211
NCBI Taxonomy	170351
IUCN Red List	192376330
IPNI	756303-1
iNaturalist	431319
GBIF	2900453
Freebase	/m/03krfl
EOL	1106532
USDA GRIN	417532
Wikipedia	Mitragyna_speciosa
CMAUP	NPO1569

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.

Accession	Assembly
Accession	Name	Level	Submitter	Released	Coverage	Size
GCA_024721245.1	ASM2472124v1	Chromosome	National Science and Technology Development Agency	2022-08-22	172.8x	660.37 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

Kratom-Induced Psychiatric Decompensation and Paranoid Delusions

Awad M, Burke HH, Oakman SA

Cureus

21-Feb-2024

PMCID:	PMC10959423
doi:	10.7759/cureus.54626
PMID:	38524086

Ecological Momentary Assessment of Self-Reported Kratom Use, Effects, and Motivations Among US Adults

Smith KE, Panlilio LV, Feldman JD, Grundmann O, Dunn KE, McCurdy CR, Garcia-Romeu A, Epstein DH

JAMA Netw Open

26-Jan-2024

PMCID:	PMC10818224
doi:	10.1001/jamanetworkopen.2023.53401
PMID:	38277146

De novo biosynthesis of antiarrhythmic alkaloid ajmaline

Guo J, Gao D, Lian J, Qu Y

Nat Commun

11-Jan-2024

PMCID:	PMC10784492
doi:	10.1038/s41467-024-44797-z
PMID:	38212296

Genome-wide identification of NAC transcription factors and regulation of monoterpenoid indole alkaloid biosynthesis in Catharanthus roseus

Ahmed J, Sajjad Y, Gatasheh MK, Ibrahim KE, Huzafa M, Khan SA, Situ C, Abbasi AM, Hassan A

Front Plant Sci

20-Dec-2023

PMCID:	PMC10785006
doi:	10.3389/fpls.2023.1286584
PMID:	38223288

Effects of yeast and dried kratom leaves (Mitragyna speciosa [Korth] Havil.) supplementation on digestibility, rumen fermentation, blood metabolites and nitrogen balance in goats

Va S, Supapong C, Chanjula P

Anim Biosci

11-Dec-2023

PMCID:	PMC10766490
doi:	10.5713/ab.23.0153
PMID:	38098130

The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids

Stander EA, Lehka B, Carqueijeiro I, Cuello C, Hansson FG, Jansen HJ, Dugé De Bernonville T, Birer Williams C, Vergès V, Lezin E, Lorensen MD, Dang TT, Oudin A, Lanoue A, Durand M, Giglioli-Guivarc’h N, Janfelt C, Papon N, Dirks RP, O’connor SE, Jensen MK, Besseau S, Courdavault V

Commun Biol

24-Nov-2023

PMCID:	PMC10673892
doi:	10.1038/s42003-023-05574-8
PMID:	38001233

Development of Methyl Ester Antibody-Based Competitive Indirect ELISA for Quantitative Detection of Mitragynine in Human Urine

Mustafa RR, Sukor R, Mohd Nor SM, Saari N, Mohsin AZ

ACS Omega

17-Nov-2023

PMCID:	PMC10734015
doi:	10.1021/acsomega.3c02734
PMID:	38144118

A target enrichment probe set for resolving phylogenetic relationships in the coffee family, Rubiaceae

Ball LD, Bedoya AM, Taylor CM, Lagomarsino LP

Appl Plant Sci

17-Nov-2023

PMCID:	PMC10719880
doi:	10.1002/aps3.11554
PMID:	38106541

A chromosome-level genome assembly of the Knoxia roxburghii (Rubiaceae)

Zhang Y, Zhang F, Jin L, Zhang T, Pu X, Qiu B, Li G

Sci Data

15-Nov-2023

PMCID:	PMC10651836
doi:	10.1038/s41597-023-02725-8
PMID:	37968303

Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism

Yunusa S, Hassan Z, Müller CP

Pharmacol Rep

04-Nov-2023

PMCID:	PMC10661785
doi:	10.1007/s43440-023-00541-w
PMID:	37924443

Microencapsulation of Mitragyna leaf extracts to be used as a bioactive compound source to enhance in vitro fermentation characteristics and microbial dynamics

Matra M, Phupaboon S, Totakul P, Prommachart R, Shah AA, Shah AM, Wanapat M

Anim Biosci

01-Nov-2023

PMCID:	PMC10766463
doi:	10.5713/ab.23.0200
PMID:	37946435

From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design

Turnaturi R, Piana S, Spoto S, Costanzo G, Reina L, Pasquinucci L, Parenti C

Molecules

14-Oct-2023

PMCID:	PMC10609244
doi:	10.3390/molecules28207089
PMID:	37894567

Abstracts for the 2023 Cannabis Clinical Outcomes Research Conference (CCORC)

N/A

Med Cannabis Cannabinoids

03-Oct-2023

PMCID:	PMC10643930
doi:	10.1159/000534044

Effect of Green and Red Thai Kratom (Mitragyna speciosa) on pancreatic digestive enzymes (alpha-glucosidase and lipase) and acetyl-carboxylase 1 activity: A possible therapeutic target for obesity prevention

Janthongkaw A, Klaophimai S, Khampaya T, Yimthiang S, Yang Y, Ma R, Bumyut A, Pouyfung P

PLoS One

21-Sep-2023

PMCID:	PMC10513218
doi:	10.1371/journal.pone.0291738
PMID:	37733688

Two Novel Iboga-Type and an Oxindole Glucuronide Alkaloid from Tabernaemontana peduncularis Disclose Related Biosynthetic Pathways to Tabernaemontana divaricata

Traxler F, Zhang H, Mahavorasirikul W, Krivanek K, Cai XH, Aiyakool W, Pfeiffer M, Brecker L, Schinnerl J

Molecules

16-Sep-2023

PMCID:	PMC10535570
doi:	10.3390/molecules28186664
PMID:	37764440

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / Corynanthean-type alkaloids
(2E)-2-[(12bS)-3-ethyl-1-formyl-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	101594616	Click to see CCC1CN2CCC3=C(C2C(C1=C(C=O)C(=O)O)C=O)NC4=CC=CC=C34	366.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2E)-2-[(1R,3S,12bR)-3-ethyl-1-formyl-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	163193411	Click to see CCC1CN2CCC3=C(C2C(C1=C(C=O)C(=O)O)C=O)NC4=CC=CC=C34	366.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2E)-2-[(1R,3S,12bS)-3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	163186493	Click to see CCC1CN2CCC3=C(C2C(C1=C(C=O)C(=O)O)C=O)NC4=C3C(=CC=C4)OC	396.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2Z)-2-[(1S,3S,12bR)-3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	154497011	Click to see CCC1CN2CCC3=C(C2C(C1=C(C=O)C(=O)O)C=O)NC4=C3C(=CC=C4)OC	396.40	unknown	https://doi.org/10.1248/CPB.52.916
(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate	611919	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1080/14786410802267627 https://doi.org/10.1016/J.ULTSONCH.2011.10.001 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-0028-1100118 https://doi.org/10.1055/S-2005-837822
2-(3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene)-3-oxopropanoic acid	162912886	Click to see CCC1CN2CCC3=C(C2C(C1=C(C=O)C(=O)O)C=O)NC4=C3C(=CC=C4)OC	396.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
7-Hydroxymitragynine	44301524	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1016/J.LFS.2003.09.054 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1248/CPB.52.916
7beta-Hydroxy-7H-mitraciliatine	102232174	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	via CMAUP database
Corynan-16-carboxylic acid, 16,17-didehydro-9,17-dimethoxy-, methyl ester, (16E)-	57856495	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1007/S11418-005-0001-7
Corynantheidine	3000341	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34	368.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
Isocorynantheidine	10948612	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34	368.50	unknown	https://doi.org/10.1055/S-0028-1097448 https://doi.org/10.1007/S11418-005-0001-7
Isopaynantheine	101804033	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-(3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	126456098	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-[(2S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	101281070	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-[(2S,3S,7aR,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	102185145	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	https://doi.org/10.1007/S11418-005-0001-7
methyl (Z)-2-[(2R,3S,12bR)-3-ethenyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	163185294	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X
methyl (Z)-2-[(2S,3R,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	26176707	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(2S,3S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	44301515	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	15560578	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1055/S-0028-1100118
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	415704	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34	368.50	unknown	https://doi.org/10.1055/S-0028-1100055
Methyl 2-(3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	74987192	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822
methyl 2-[(2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	92204	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	via CMAUP database
Methyl 9,17-dimethoxycoryna-16,18-dien-16-carboxylate	78299295	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1111/J.2042-7158.1965.TB07599.X
Mitraciliatine	11741588	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	via CMAUP database
Mitragynine	3034396	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/J.LFS.2003.09.054 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1002/CHIN.200452220 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/J.ULTSONCH.2011.10.001 https://doi.org/10.1016/0378-8741(88)90121-3 https://doi.org/10.1016/0378-8741(89)90053-6 https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/0031-9422(91)84152-I https://doi.org/10.1080/14786410802267627 https://doi.org/10.1007/S11418-005-0001-7 https://doi.org/10.1016/S0306-3623(98)00265-1
Paynantheine	3037629	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1055/S-0028-1097448 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1007/S11418-005-0001-7
Speciociliatine	15560576	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822
Speciogynine	15560577	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822
> Alkaloids and derivatives / Yohimbine alkaloids
3-Isoajmalicine	11416867	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45	352.40	unknown	https://doi.org/10.1055/S-0028-1097448
Ajmalicine	441975	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45	352.40	unknown	https://doi.org/10.1055/S-0028-1100055
Lamuran	251561	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45	352.40	unknown	https://doi.org/10.1055/S-0028-1100055
methyl (1R,15R,16S,20S)-8-methoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,18-pentaene-19-carboxylate	154497013	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=C4C(=CC=C5)OC	382.50	unknown	https://doi.org/10.1055/S-0028-1097448
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Ethane	6324	Click to see CC	30.07	unknown	via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol	234817	Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O	358.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
Pinoresinol	73399	Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O	358.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Ursolic Acid	64945	Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O	456.70	unknown	https://doi.org/10.1055/S-2006-960132
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives
(3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione	12968604	Click to see CC(C1C(=O)NCC(=O)N1)O	158.16	unknown	https://doi.org/10.1055/S-0028-1097410
> Organic acids and derivatives / Carboxylic acids and derivatives / Tetracarboxylic acids and derivatives
[(Z,2S,3R,5S,8E)-3,5-diacetyloxy-8-(5-oxofuran-2-ylidene)oct-6-en-2-yl] acetate	134840879	Click to see CC(C(CC(C=CC=C1C=CC(=O)O1)OC(=O)C)OC(=O)C)OC(=O)C	366.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
methyl (E)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163074631	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
methyl (Z)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	154497839	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(3R,6'S,7'R,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163187294	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1100118
methyl (Z)-2-[(3R,6'S,7'S,8'aR)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163074633	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
methyl 2-(6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate	634020	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1100118
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
(1S,2S,3S)-2-[(E)-1,3-dimethoxy-3-oxoprop-1-en-2-yl]-3-ethyl-8-methoxy-2,3,4,6,7,12-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-1-sulfonate	10552557	Click to see CCC1C[N+]2=C(C(C1C(=COC)C(=O)OC)S(=O)(=O)[O-])C3=C(CC2)C4=C(N3)C=CC=C4OC	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1248/CPB.52.916
(8S)-8-ethyl-15-methoxy-5-oxo-4-oxa-10,20-diazapentacyclo[11.7.0.02,10.03,7.014,19]icosa-1(13),2,6,14(19),15,17-hexaene-6-carbaldehyde	10690137	Click to see CCC1CN2CCC3=C(C2=C4C1=C(C(=O)O4)C=O)NC5=C3C(=CC=C5)OC	364.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1248/CPB.52.916
Corynantheidinaline	14804152	Click to see CCC1=C(C(=C2C3=C(CCN2C1=O)C4=CC=CC=C4N3)C=O)C(=O)OC	350.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
methyl (2E)-2-[(3S)-3-ethyl-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoate	154496384	Click to see CCC1CN2CCC3=C(C2=CC1=C(C=O)C(=O)OC)NC4=CC=CC=C34	350.40	unknown	https://doi.org/10.1248/CPB.52.916
methyl (2E)-2-[(3S)-3-ethyl-8-methoxy-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoate	101091694	Click to see CCC1CN2CCC3=C(C2=CC1=C(C=O)C(=O)OC)NC4=C3C(=CC=C4)OC	380.40	unknown	https://doi.org/10.1248/CPB.52.916
methyl (8R)-8-ethyl-15-methoxy-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14(19),15,17-hexaene-5-carboxylate	11486236	Click to see CCC12CN3CCC4=C(C3=CC1=C(C(=O)O2)C(=O)OC)NC5=C4C(=CC=C5)OC	394.40	unknown	https://doi.org/10.1248/CPB.52.916 https://doi.org/10.1016/S0040-4020(00)00235-0
methyl (8R)-8-ethyl-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14,16,18-hexaene-5-carboxylate	10522789	Click to see CCC12CN3CCC4=C(C3=CC1=C(C(=O)O2)C(=O)OC)NC5=CC=CC=C45	364.40	unknown	https://doi.org/10.1248/CPB.52.916 https://doi.org/10.1021/JO9823644
methyl (E)-2-[(2S,3S)-3-ethyl-8-methoxy-2,3,4,12-tetrahydro-1H-indolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate	10741318	Click to see CCC1C[N+]2=C(CC1C(=COC)C(=O)OC)C3=C(C=C2)C4=C(N3)C=CC=C4OC	395.50	unknown	via CMAUP database
methyl 2-(3-ethyl-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene)-3-oxopropanoate	163106866	Click to see CCC1CN2CCC3=C(C2=CC1=C(C=O)C(=O)OC)NC4=CC=CC=C34	350.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
Methyl 8-ethyl-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14,16,18-hexaene-5-carboxylate	10784982	Click to see CCC12CN3CCC4=C(C3=CC1=C(C(=O)O2)C(=O)OC)NC5=CC=CC=C45	364.40	unknown	https://doi.org/10.1021/JO9823644
Mitragynaline	636690	Click to see CCC1=C(C(=C2C3=C(CCN2C1=O)C4=C(N3)C=CC=C4OC)C=O)C(=O)OC	380.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/0031-9422(91)84152-I https://doi.org/10.1016/S0040-4039(01)00006-5
> Organoheterocyclic compounds / Indolizidines
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester	98363	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O	368.40	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X https://doi.org/10.1055/S-0028-1100055
Corynoxeine	44568160	Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC	382.50	unknown	https://doi.org/10.1055/S-0028-1097410
Corynoxine	10475115	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
Corynoxine B	10091424	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097410
Isomitraphylline	11726520	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O	368.40	unknown	https://doi.org/10.1055/S-0028-1097448
Isopteropodine	9885603	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O	368.40	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X https://doi.org/10.1055/S-0028-1100055
Isorhynchophylline	3037048	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097448
Isorotundifoline	102232176	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	via CMAUP database
Isospeciofoleine	102232175	Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=C(C=CC=C4O)NC3=O)C(=O)OC	398.50	unknown	via CMAUP database
Isospeciofoline	101289836	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	via CMAUP database
methyl (1S,4aS,5aS,6S,10aR)-4'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate	162941828	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=C(C=CC=C5OC)NC4=O	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890763	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(3S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890766	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(6'S,7'S)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	5316104	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
methyl (Z)-2-[(3R,6'R,7'S,8'aS)-6'-ethenyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162919730	Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=C(C=CC=C4OC)NC3=O)C(=O)OC	412.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(3S,6'R,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890765	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
Mitrafo;ine	101666873	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
Speciophylline	168985	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O	368.40	unknown	https://doi.org/10.1055/S-0028-1097410
> Organoheterocyclic compounds / Quinolizines
(1S,2S,3S)-2-[(Z)-1,3-dimethoxy-3-oxoprop-1-en-2-yl]-3-ethyl-8-methoxy-2,3,4,6,7,12-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-1-sulfonate	154497014	Click to see CCC1C[N+]2=C(C(C1C(=COC)C(=O)OC)S(=O)(=O)[O-])C3=C(CC2)C4=C(N3)C=CC=C4OC	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
2-(1,3-Dimethoxy-3-oxoprop-1-en-2-yl)-3-ethyl-8-methoxy-1,2,3,4,6,7-hexahydroindolo[2,3-a]quinolizine-1-sulfonic acid	163187725	Click to see CCC1CN2CCC3=C4C(=NC3=C2C(C1C(=COC)C(=O)OC)S(=O)(=O)O)C=CC=C4OC	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Epicatechin	72276	Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O	290.27	unknown	https://doi.org/10.1016/S0031-9422(00)83771-1
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol	5280863	Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O	286.24	unknown	via CMAUP database
Quercetin	5280343	Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O	302.23	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Astragalin	5282102	Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O	448.40	unknown	via CMAUP database
Hyperoside	5281643	Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O	464.40	unknown	via CMAUP database
Isoquercetin	5280804	Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O	464.40	unknown	via CMAUP database
Quercitrin	5280459	Click to see CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O	448.40	unknown	via CMAUP database
Rutin	5280805	Click to see CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O	610.50	unknown	via CMAUP database

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Mitragyna speciosa

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