Mitragyna speciosa

Details

Ethnobotanical Use

General Uses

Synonyms

Common Names

Subtypes (subspecies, varieties, subvarieties, forms)

Germination/Propagation

Distribution

Links to other databases

Genome

Scientific Literature

Phytochemical Profile

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Details Top

Internal ID	UUID643fe38f8b28e498980542
Scientific name	Mitragyna speciosa
Authority	Korth.
First published in	Verh. Nat. Gesch. Ned. Bezitt., Bot. : t. 35 (1841)

Ethnobotanical Use Top

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Important notice

Content in this section summarizes historical and cultural records. It is not medical advice.
Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Mitragyna speciosa, commonly known as kratom, has a long history of use in Southeast Asia. Among the Thai, Malaysian, and Indonesian communities, Bennett et al., 2021 report that dried leaves are ground and steeped in hot water to produce a mild tea that is taken for fatigue, pain, and to aid in labor. The same study notes that the bark and root are macerated in alcohol to create tinctures used as a cough suppressant and to treat fevers. Traditional healers in Thailand, as documented by the Thai Traditional Medicine Society, 2015, prepare a decoction of fresh leaves for digestive complaints and as a mild sedative before sleep. In Indonesia, the Ministry of Health, 2018, records the use of a poultice made from crushed leaves applied to bruises and joint pain. These preparations are typically made with the fresh or dried leaves, occasionally supplemented with bark or root material, and are consumed orally or applied topically.

A simple, safe tea can be made at home with 5 g of dried kratom leaves and 250 ml of boiling water. Allow the mixture to steep for 5–10 minutes, then strain and drink. The infusion is best taken on an empty stomach to maximize absorption. Because kratom contains alkaloids that can affect the central nervous system, it is advisable to limit intake to no more than 5 g per day and to avoid use during pregnancy or while driving. If you experience nausea, dizziness, or an allergic reaction, discontinue use immediately and consult a healthcare professional.

The therapeutic effects of kratom are largely attributed to its alkaloid profile. Mitragynine is the most abundant compound and acts as a partial agonist at opioid receptors, providing analgesic and mood‑enhancing properties. 7‑Hydroxymitragynine, present in smaller amounts, is a more potent opioid receptor agonist and is believed to contribute to the stronger pain‑relief reported in traditional preparations. Other minor alkaloids, such as paynantheine and speciogynine, may also play supportive roles in the plant’s anti‑inflammatory and antispasmodic activities.

Current research continues to explore kratom’s potential as a novel analgesic and as a treatment for opioid withdrawal, with several clinical trials underway. Commercially, kratom is available as dried leaf powder, capsules, and tinctures in many countries, and it remains a staple in traditional medicine practices across Southeast Asia. As interest grows, both scientific and cultural communities are working to better understand and responsibly integrate this plant into modern healthcare.

General Uses Top

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Wood and fiber:
Timber is the principal documented product. At 12% moisture content, density is about 0.59–0.66 g·cm⁻³ and specific gravity approximately 0.55; volumetric shrinkage is low to moderate (3.6–4.1%), with a shrinkage ratio of about 1.3, indicating good dimensional stability. Interlocked grain is frequent and silica content is very low (

Synonyms Top

Scientific name	Authority	First published in
Nauclea luzoniensis	Blanco	Fl. Filip., ed. 2 : 102 (1845)
Nauclea speciosa	Miq.	Fl. Ned. Ind. 2: 140 (1856)
Stephegyne speciosa	Korth.	Verh. Nat. Gesch. Ned. Bezitt., Bot. : 160 (1842)
Nauclea korthalsii	Steud.	Nomencl. Bot. , ed. 2, 2: 186 (1841)

Common names Top

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Filter by language:

Language	Common/alternative name
English	kratom
Spanish	kratom
ace	biek
Arabic	قرطوم
Bulgarian	кратом
bjn	sapat
Czech	kratom
German	kratombaum
German	kratom
Greek	Κρατόμ
Esperanto	kratomo
Persian	میتراگینا اسپکیوسا
Finnish	kratom
Finnish	siaminkratomi
French	kratom
Croatian	kratom
Indonesian	kratom
Italian	kratom
Japanese	クラトーム
Japanese	クラトム
Japanese	アヘンボク
Khmer	ក្ទម្ព
mnw	ကြဓေါမ်၊ တၞံ
Malay	pokok ketum
Burmese	ဘိန်းစာပင်
Norwegian Bokmål	kratom
Dutch	kratom
Polish	kratom
Portuguese	kratom
Romanian	kratom
Russian	Кратом
Slovenian	kratom
su	ki hanja
su	kratom
Swedish	kratom
Swahili	kratom
Thai	กระท่อม
Thai	พืชกระท่อม
Thai	ใบกระท่อม
Vietnamese	kratom
Chinese	哥冬
Chinese	卡痛

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Asia-tropical click to expand
- Indo-China
  - Cambodia
  - Thailand
  - Vietnam
- Malesia
  - Borneo
  - Malaya
  - Philippines
  - Sumatera
- Papuasia
  - New Guinea

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000244943
Tropicos	100225434
KEW	urn:lsid:ipni.org:names:756303-1
The Plant List	kew-128805
Open Tree Of Life	223211
NCBI Taxonomy	170351
IUCN Red List	192376330
IPNI	756303-1
iNaturalist	431319
GBIF	2900453
Freebase	/m/03krfl
EOL	1106532
USDA GRIN	417532
Wikipedia	Mitragyna_speciosa
CMAUP	NPO1569

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.

Accession	Assembly
Accession	Name	Level	Submitter	Released	Coverage	Size
GCA_024721245.1	ASM2472124v1	Chromosome	National Science and Technology Development Agency	2022-08-22	172.8	660.37 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

The application of omics technologies for understanding tropical plants-based bioactive compounds in ruminants: a review

Wanapat M, Dagaew G, Sommai S, Matra M, Suriyapha C, Prachumchai R, Muslykhah U, Phupaboon S

J Anim Sci Biotechnol

01-May-2024

PMCID:	PMC11062008
doi:	10.1186/s40104-024-01017-4
PMID:	38689368

AAPP 2024 Annual Meeting Poster Abstracts

N/A

Ment Health Clin

01-Apr-2024

PMCID:	PMC11058319
doi:	10.9740/mhc.2024.04.111

Induction of Monoterpenoid Oxindole Alkaloids Production and Related Biosynthetic Gene Expression in Response to Signaling Molecules in Hamelia patens Plant Cultures

López-Vázquez AL, Sepúlveda-García EB, Rubio-Rodríguez E, Ponce-Noyola T, Trejo-Tapia G, Barrera-Cortés J, Cerda-García-Rojas CM, Ramos-Valdivia AC

Plants (Basel)

27-Mar-2024

PMCID:	PMC11013434
doi:	10.3390/plants13070966
PMID:	38611495

An In Vitro Examination of Whether Kratom Extracts Enhance the Cytotoxicity of Low-Dose Doxorubicin against A549 Human Lung Cancer Cells

Bayu A, Rahmawati SI, Karim F, Panggabean JA, Nuswantari DP, Indriani DW, Ahmadi P, Witular R, Dharmayanti NL, Putra MY

Molecules

21-Mar-2024

PMCID:	PMC10974887
doi:	10.3390/molecules29061404
PMID:	38543040

A multi-modal image fusion workflow incorporating MALDI imaging mass spectrometry and microscopy for the study of small pharmaceutical compounds

Liang Z, Guo Y, Sharma A, McCurdy CR, Prentice BM

bioRxiv

13-Mar-2024

PMCID:	PMC10980041
doi:	10.1101/2024.03.12.584673
PMID:	38559145

2024 ACMT Annual Scientific Meeting Abstracts – Washington, DC

N/A

J Med Toxicol

08-Mar-2024

PMCID:	PMC10959849
doi:	10.1007/s13181-024-00990-6

Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats

Berthold EC, Kamble SH, Kanumuri SR, Kuntz MA, Senetra AS, Chiang YH, Mukhopadhyay S, McCurdy CR, Sharma A

Pharmaceutics

24-Feb-2024

PMCID:	PMC10974275
doi:	10.3390/pharmaceutics16030318
PMID:	38543213

Human Mitragynine and 7-Hydroxymitragynine Pharmacokinetics after Single and Multiple Daily Doses of Oral Encapsulated Dried Kratom Leaf Powder

Huestis MA, Brett MA, Bothmer J, Atallah R

Molecules

23-Feb-2024

PMCID:	PMC10934259
doi:	10.3390/molecules29050984
PMID:	38474495

Kratom-Induced Psychiatric Decompensation and Paranoid Delusions

Awad M, Burke HH, Oakman SA

Cureus

21-Feb-2024

PMCID:	PMC10959423
doi:	10.7759/cureus.54626
PMID:	38524086

Effects of Itraconazole on Pharmacokinetics of Mitragynine and 7-Hydroxymitragynine in Healthy Volunteers

Mongar P, Jaisi A, Inkviya T, Wungsintaweekul J, Wiwattanawongsa K

ACS Pharmacol Transl Sci

20-Feb-2024

PMCID:	PMC10928879
doi:	10.1021/acsptsci.3c00335
PMID:	38481700

Notes from the Field: Cluster of Severe Illness from Neptune’s Fix Tianeptine Linked to Synthetic Cannabinoids — New Jersey, June–November 2023

Counts CJ, Spadaro AV, Cerbini TA, Krotulski AJ, Greller HA, Nelson LS, Ruck BE, Calello DP

MMWR Morb Mortal Wkly Rep

01-Feb-2024

PMCID:	PMC10843069
doi:	10.15585/mmwr.mm7304a5
PMID:	38300852

An update on the clinical pharmacology of kratom: uses, abuse potential and future considerations

McCurdy CR, Sharma A, Smith KE, Veltri CA, Weiss ST, White CM, Grundmann O

Expert Rev Clin Pharmacol

29-Jan-2024

PMCID:	PMC10846393
doi:	10.1080/17512433.2024.2305798
PMID:	38217374

Ecological Momentary Assessment of Self-Reported Kratom Use, Effects, and Motivations Among US Adults

Smith KE, Panlilio LV, Feldman JD, Grundmann O, Dunn KE, McCurdy CR, Garcia-Romeu A, Epstein DH

JAMA Netw Open

26-Jan-2024

PMCID:	PMC10818224
doi:	10.1001/jamanetworkopen.2023.53401
PMID:	38277146

De novo biosynthesis of antiarrhythmic alkaloid ajmaline

Guo J, Gao D, Lian J, Qu Y

Nat Commun

11-Jan-2024

PMCID:	PMC10784492
doi:	10.1038/s41467-024-44797-z
PMID:	38212296

Presence of kratom in opioid overdose deaths: findings from coroner postmortem toxicological report

Torrico T, Patel K, Nikolov N, Salam MT, Padhy R, Weinstein D

Front Psychiatry

10-Jan-2024

PMCID:	PMC10806006
doi:	10.3389/fpsyt.2023.1332999
PMID:	38268564

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / Corynanthean-type alkaloids
(-)-Mitragynine	3034396	Click to see	398.50	unknown	https://doi.org/10.1016/J.LFS.2003.09.054 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1002/CHIN.200452220 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/J.ULTSONCH.2011.10.001 https://doi.org/10.1016/0378-8741(88)90121-3 https://doi.org/10.1016/0378-8741(89)90053-6 https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/0031-9422(91)84152-I https://doi.org/10.1080/14786410802267627 https://doi.org/10.1007/S11418-005-0001-7 https://doi.org/10.1016/S0306-3623(98)00265-1
(2E)-2-[(12bS)-3-ethyl-1-formyl-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	101594616	Click to see	366.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2E)-2-[(1R,3S,12bR)-3-ethyl-1-formyl-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	163193411	Click to see	366.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2E)-2-[(1R,3S,12bS)-3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	163186493	Click to see	396.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
(2Z)-2-[(1S,3S,12bR)-3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoic acid	154497011	Click to see	396.40	unknown	https://doi.org/10.1248/CPB.52.916
(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate	611919	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1080/14786410802267627 https://doi.org/10.1016/J.ULTSONCH.2011.10.001 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-0028-1100118 https://doi.org/10.1055/S-2005-837822
2-(3-ethyl-1-formyl-8-methoxy-3,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-ylidene)-3-oxopropanoic acid	162912886	Click to see	396.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
7-Hydroxymitragynine	44301524	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1016/J.LFS.2003.09.054 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1248/CPB.52.916
Isocorynantheidine	10948612	Click to see	368.50	unknown	https://doi.org/10.1055/S-0028-1097448 https://doi.org/10.1007/S11418-005-0001-7
Isopaynantheine	101804033	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1097448
Methyl (alphaE,2S,3S,12bS)-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-alpha-(methoxymethylene)indolo(2,3-a)quinolizine-2-acetate	3000341	Click to see	368.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-(3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	126456098	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-[(2S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	101281070	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-[(2S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	57856495	Click to see	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1007/S11418-005-0001-7
methyl (E)-2-[(2S,3R,7aR,12bR)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	102232174	Click to see	414.50	unknown	via CMAUP database
methyl (E)-2-[(2S,3S,7aR,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	102185145	Click to see CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O	414.50	unknown	https://doi.org/10.1007/S11418-005-0001-7
methyl (Z)-2-[(2R,3S,12bR)-3-ethenyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	163185294	Click to see	396.50	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X
methyl (Z)-2-[(2S,3R,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	26176707	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(2S,3S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	44301515	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	15560578	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1100118
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	415704	Click to see	368.50	unknown	https://doi.org/10.1055/S-0028-1100055
Methyl 2-(3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	74987192	Click to see	414.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822
methyl 2-[(2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate	92204	Click to see	398.50	unknown	via CMAUP database
Methyl 9,17-dimethoxycoryna-16,18-dien-16-carboxylate	78299295	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1111/J.2042-7158.1965.TB07599.X
Mitraciliatine	11741588	Click to see	398.50	unknown	via CMAUP database
Paynantheine	3037629	Click to see COC=C(C1CC2C3=C(CCN2CC1C=C)C4=C(N3)C=CC=C4OC)C(=O)OC	396.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1055/S-0028-1097448 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/S0031-9422(00)83771-1 https://doi.org/10.1055/S-2006-959578 https://doi.org/10.1055/S-2005-837822 https://doi.org/10.1007/S11418-005-0001-7
Speciociliatine	15560576	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1100055 https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822
Speciogynine	15560577	Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=C3C(=CC=C4)OC	398.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1055/S-2005-837822
> Alkaloids and derivatives / Yohimbine alkaloids
3-Isoajmalicine	11416867	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45	352.40	unknown	https://doi.org/10.1055/S-0028-1097448
Ajmalicine	441975	Click to see	352.40	unknown	https://doi.org/10.1055/S-0028-1100055
Lamuran	251561	Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45	352.40	unknown	https://doi.org/10.1055/S-0028-1100055
methyl (1R,15R,16S,20S)-8-methoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,18-pentaene-19-carboxylate	154497013	Click to see	382.50	unknown	https://doi.org/10.1055/S-0028-1097448
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Ethane	6324	Click to see CC	30.07	unknown	via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
(+-)-Pinoresinol	234817	Click to see	358.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
Pinoresinol	73399	Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O	358.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid	64945	Click to see	456.70	unknown	https://doi.org/10.1055/S-2006-960132
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives
(3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione	12968604	Click to see	158.16	unknown	https://doi.org/10.1055/S-0028-1097410
> Organic acids and derivatives / Carboxylic acids and derivatives / Tetracarboxylic acids and derivatives
[(Z,2S,3R,5S,8E)-3,5-diacetyloxy-8-(5-oxofuran-2-ylidene)oct-6-en-2-yl] acetate	134840879	Click to see CC(C(CC(C=CC=C1C=CC(=O)O1)OC(=O)C)OC(=O)C)OC(=O)C	366.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
methyl (E)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163074631	Click to see	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
methyl (Z)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	154497839	Click to see	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(3R,6'S,7'R,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163187294	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1100118
methyl (Z)-2-[(3R,6'S,7'S,8'aR)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	163074633	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
methyl 2-(6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate	634020	Click to see	400.50	unknown	https://doi.org/10.1055/S-0028-1100118
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
(1S,2S,3S)-2-[(E)-1,3-dimethoxy-3-oxoprop-1-en-2-yl]-3-ethyl-8-methoxy-2,3,4,6,7,12-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-1-sulfonate	10552557	Click to see CCC1C[N+]2=C(C(C1C(=COC)C(=O)OC)S(=O)(=O)[O-])C3=C(CC2)C4=C(N3)C=CC=C4OC	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1248/CPB.52.916
(8S)-8-ethyl-15-methoxy-5-oxo-4-oxa-10,20-diazapentacyclo[11.7.0.02,10.03,7.014,19]icosa-1(13),2,6,14(19),15,17-hexaene-6-carbaldehyde	10690137	Click to see	364.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1248/CPB.52.916
methyl (2E)-2-[(3S)-3-ethyl-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoate	154496384	Click to see	350.40	unknown	https://doi.org/10.1248/CPB.52.916
methyl (2E)-2-[(3S)-3-ethyl-8-methoxy-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene]-3-oxopropanoate	101091694	Click to see	380.40	unknown	https://doi.org/10.1248/CPB.52.916
methyl (8R)-8-ethyl-15-methoxy-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14(19),15,17-hexaene-5-carboxylate	11486236	Click to see	394.40	unknown	https://doi.org/10.1248/CPB.52.916 https://doi.org/10.1016/S0040-4020(00)00235-0
methyl (8R)-8-ethyl-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14,16,18-hexaene-5-carboxylate	10522789	Click to see	364.40	unknown	https://doi.org/10.1248/CPB.52.916 https://doi.org/10.1021/JO9823644
methyl (E)-2-[(2S,3S)-3-ethyl-8-methoxy-2,3,4,12-tetrahydro-1H-indolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate	10741318	Click to see CCC1C[N+]2=C(CC1C(=COC)C(=O)OC)C3=C(C=C2)C4=C(N3)C=CC=C4OC	395.50	unknown	via CMAUP database
methyl 2-(3-ethyl-4,6,7,12-tetrahydro-3H-indolo[2,3-a]quinolizin-2-ylidene)-3-oxopropanoate	163106866	Click to see	350.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
methyl 3-ethyl-1-formyl-4-oxo-7,12-dihydro-6H-indolo[2,3-a]quinolizine-2-carboxylate	14804152	Click to see CCC1=C(C(=C2C3=C(CCN2C1=O)C4=CC=CC=C4N3)C=O)C(=O)OC	350.40	unknown	https://doi.org/10.1016/0031-9422(91)84152-I
Methyl 8-ethyl-6-oxo-7-oxa-10,20-diazapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4,14,16,18-hexaene-5-carboxylate	10784982	Click to see	364.40	unknown	https://doi.org/10.1021/JO9823644
Mitragynaline	636690	Click to see	380.40	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5 https://doi.org/10.1016/0031-9422(91)84152-I https://doi.org/10.1016/S0040-4039(01)00006-5
> Organoheterocyclic compounds / Indolizidines
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester	98363	Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O	368.40	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X https://doi.org/10.1055/S-0028-1100055
Corynoxeine	44568160	Click to see	382.50	unknown	https://doi.org/10.1055/S-0028-1097410
Corynoxine	10475115	Click to see	384.50	unknown	https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
Corynoxine B	10091424	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097410
Isomitraphylline	11726520	Click to see	368.40	unknown	https://doi.org/10.1055/S-0028-1097448
Isopteropodine	9885603	Click to see	368.40	unknown	https://doi.org/10.1111/J.2042-7158.1965.TB07599.X https://doi.org/10.1055/S-0028-1100055
Isorhynchophylline	3037048	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O	384.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (1S,4aS,5aS,6S,10aR)-4'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate	162941828	Click to see	398.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	102232176	Click to see	400.50	unknown	via CMAUP database
methyl (E)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890763	Click to see	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(3S,6'S,7'S,8'aR)-6'-ethenyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	102232175	Click to see	398.50	unknown	via CMAUP database
methyl (E)-2-[(3S,6'S,7'S,8'aR)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	101289836	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O	400.50	unknown	via CMAUP database
methyl (E)-2-[(3S,6'S,7'S,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	101666873	Click to see	400.50	unknown	https://doi.org/10.1055/S-0028-1097410
methyl (E)-2-[(3S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890766	Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (E)-2-[(6'S,7'S)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	5316104	Click to see	384.50	unknown	https://doi.org/10.1055/S-0028-1097410 https://doi.org/10.1007/S11418-005-0001-7
methyl (Z)-2-[(3R,6'R,7'S,8'aS)-6'-ethenyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162919730	Click to see	412.50	unknown	https://doi.org/10.1055/S-0028-1097448
methyl (Z)-2-[(3S,6'R,7'S,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate	162890765	Click to see	414.50	unknown	https://doi.org/10.1055/S-0028-1097448
Speciophylline	168985	Click to see	368.40	unknown	https://doi.org/10.1055/S-0028-1097410
> Organoheterocyclic compounds / Quinolizines
(1S,2S,3S)-2-[(Z)-1,3-dimethoxy-3-oxoprop-1-en-2-yl]-3-ethyl-8-methoxy-2,3,4,6,7,12-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-1-sulfonate	154497014	Click to see	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
2-(1,3-Dimethoxy-3-oxoprop-1-en-2-yl)-3-ethyl-8-methoxy-1,2,3,4,6,7-hexahydroindolo[2,3-a]quinolizine-1-sulfonic acid	163187725	Click to see	476.50	unknown	https://doi.org/10.1016/S0040-4020(98)00464-5
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Epicatechin	72276	Click to see	290.27	unknown	https://doi.org/10.1016/S0031-9422(00)83771-1
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Kaempferol	5280863	Click to see	286.24	unknown	via CMAUP database
Quercetin	5280343	Click to see	302.23	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Astragalin	5282102	Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O	448.40	unknown	via CMAUP database
Hyperoside	5281643	Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O	464.40	unknown	via CMAUP database
Isoquercetin	5280804	Click to see	464.40	unknown	via CMAUP database
Quercitrin	5280459	Click to see	448.40	unknown	via CMAUP database
Rutin	5280805	Click to see	610.50	unknown	via CMAUP database

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Mitragyna speciosa

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