Ruta angustifolia

Details Top

Internal ID UUID6440000738357207338855
Scientific name Ruta angustifolia
Authority Pers.
First published in Syn. Pl. 1: 464 (1805)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

No reliable ethnobotanical source identifies infusions (teas), decoctions, tinctures, macerations, or poultices prepared from Ruta angustifolia (Pers.). In the absence of documented traditional practices and named cultures for this species, the site should not present ethnobotanical usage claims.

General Uses Top

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Fragrance and cosmetics:
The leaf essential oil is employed in perfumery for its aromatic profile. It is characterized by a predominance of aliphatic methyl ketones, notably 2-nonanone and 2-undecanone, which confer a sharp, fruity–herbaceous note. Oil composition varies with chemotype and geography; the ketones comprise the major fraction in many populations. Safety evaluation indicates the oil is phototoxic and irritant, and its use in cosmetics is restricted under IFRA Standards (especially Recommendation 41) and EU Cosmetic Regulation Annex II.

Properties relevant to use:
The oil’s ketone-rich chemistry provides strong odor impact and low olfactory threshold. However, the same constituents confer phototoxicity and skin sensitization potential, limiting topical applications and mandating concentration caps and labeling in consumer products.

Standards and regulation:
Use of Ruta angustifolia leaf oil in cosmetics is controlled by the International Fragrance Association (IFRA) standards (Recommendation 41 for Ruta oils) and listed as a prohibited fragrance allergen in the EU Cosmetic Regulation Annex II when used as a fragrance ingredient. National pharmacopoeias do not recognize this taxon for medicinal purposes.

Sustainability and sourcing:
Commercial supply is primarily from Mediterranean regions; harvesting can stress wild populations where overharvest occurs. Traceability and cultivated sourcing are recommended to reduce pressure on wild stands.

Synonyms Top

No known synonyms.

Common names Top

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Language Common/alternative name
Spanish ruda bravia
Spanish ruda bravía
Spanish ruda silvestre menor
Arabic سذاب مصري
Catalan ruda de fulla estreta
French rue à feuilles étroites
Malay pokok garuda

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Europe
    • Southeastern Europe
      • Italy
      • Sicilia
      • Yugoslavia
    • Southwestern Europe
      • Baleares
      • Corse
      • France
      • Portugal
      • Sardegna
      • Spain

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000463817
Tropicos 28101495
INPN 119707
Flora of Italy 2987
KEW urn:lsid:ipni.org:names:775060-1
The Plant List kew-2527510
Open Tree Of Life 1081358
Observations.org 121611
NCBI Taxonomy 452789
IPNI 775060-1
iNaturalist 82849
GBIF 3832875
EPPO RUAAN
Elurikkus 420992

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Latin American Plants against Microorganisms Cuevas-Cianca SI, Romero-Castillo C, Gálvez-Romero JL, Sánchez-Arreola E, Juárez ZN, Hernández LR Plants (Basel) 28-Nov-2023
PMCID:PMC10708099
doi:10.3390/plants12233997
PMID:38068631
Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors Mollova-Sapundzhieva Y, Angelov P, Georgiev D, Yanev P Beilstein J Org Chem 23-Nov-2023
PMCID:PMC10682542
doi:10.3762/bjoc.19.132
PMID:38033452
Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities Manna S, Das K, Santra S, Nosova EV, Zyryanov GV, Halder S Viruses 28-Aug-2023
PMCID:PMC10536032
doi:10.3390/v15091826
PMID:37766233
Furoquinoline Alkaloids: Insights into Chemistry, Occurrence, and Biological Properties Szewczyk A, Pęczek F Int J Mol Sci 15-Aug-2023
PMCID:PMC10454094
doi:10.3390/ijms241612811
PMID:37628986
Cytotoxic, Anti-Hemolytic, and Antioxidant Activities of Ruta chalepensis L. (Rutaceae) Extract, Fractions, and Isolated Compounds Elizondo-Luévano JH, Rodríguez-Garza NE, Bazaldúa-Rodríguez AF, Romo-Sáenz CI, Tamez-Guerra P, Verde-Star MJ, Gomez-Flores R, Quintanilla-Licea R Plants (Basel) 02-Jun-2023
PMCID:PMC10255231
doi:10.3390/plants12112203
PMID:37299182
Role of phytocompounds as the potential anti-viral agent: an overview Mohanty SS, Sahoo CR, Paidesetty SK, Padhy RN Naunyn Schmiedebergs Arch Pharmacol 09-May-2023
PMCID:PMC10169142
doi:10.1007/s00210-023-02517-2
PMID:37160482
Microscopic and physicochemical evaluation of Ruta angustifolia leaves Wahyuni TS, Khoiriyah N, Tumewu L, Ekasari W, Fuad A, Widyawaruyanti A J Public Health Afr 16-Mar-2023
PMCID:PMC10365675
doi:10.4081/jphia.2023.2520
PMID:37492534
Promising alkaloids and flavonoids compounds as anti-hepatitis c virus agents: a review Rizaldi G, Hafid AF, Wahyuni TS J Public Health Afr 16-Mar-2023
PMCID:PMC10365654
doi:10.4081/jphia.2023.2514
PMID:37492538
Ruta angustifolia Pers. (Narrow-Leaved Fringed Rue): Pharmacological Properties and Phytochemical Profile Bailly C Plants (Basel) 13-Feb-2023
PMCID:PMC9959652
doi:10.3390/plants12040827
PMID:36840175
Plastome evolution and phylogeny of the tribe Ruteae (Rutaceae) Liu Q, Gao Y, Dong W, Zhao L Ecol Evol 09-Feb-2023
PMCID:PMC9911629
doi:10.1002/ece3.9821
PMID:36789335
Medicinal Plants Used Traditionally for Skin Related Problems in the South Balkan and East Mediterranean Region—A Review Tsioutsiou EE, Amountzias V, Vontzalidou A, Dina E, Stevanović ZD, Cheilari A, Aligiannis N Front Pharmacol 05-Jul-2022
PMCID:PMC9294246
doi:10.3389/fphar.2022.936047
PMID:35865952
Essential Oils in Respiratory Mycosis: A Review Zuzarte M, Salgueiro L Molecules 28-Jun-2022
PMCID:PMC9268412
doi:10.3390/molecules27134140
PMID:35807386
Ethnoveterinary Medicine and Ethnopharmacology in the Main Transhumance Areas of Castilla-La Mancha (Spain) Rivera D, Verde A, Fajardo Rodríguez J, Ríos S, Alcaraz F, Cárceles C, Ortíz J, Valdés A, Ruíz-Gallardo JR, García-Flores A, Palazón JA, Obón C Front Vet Sci 03-May-2022
PMCID:PMC9113055
doi:10.3389/fvets.2022.866132
PMID:35591874
Bioactive Based Nanocarriers for the Treatment of Viral Infections and SARS-CoV-2 Goyal R, Bala R, Sindhu RK, Zehravi M, Madaan R, Ramproshad S, Mondal B, Dey A, Rahman MH, Cavalu S Nanomaterials (Basel) 01-May-2022
PMCID:PMC9104170
doi:10.3390/nano12091530
PMID:35564239
Niche Variation in Endemic Lilium pomponium on a Wide Altitudinal Gradient in the Maritime Alps Fontaine N, Gauthier P, Casazza G, Thompson JD Plants (Basel) 21-Mar-2022
PMCID:PMC8954139
doi:10.3390/plants11060833
PMID:35336714

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohol esters
Nonyl Acetate 8918 Click to see CCCCCCCCCOC(=O)C 186.29 unknown https://doi.org/10.1080/10412905.1991.9697956
Octyl Acetate 8164 Click to see 172.26 unknown https://doi.org/10.1080/10412905.1991.9697956
Undecyl acetate 15605 Click to see 214.34 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
1-Decanol 8174 Click to see 158.28 unknown https://doi.org/10.1080/10412905.1991.9697956
1-Undecanol 8184 Click to see 172.31 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Nonanol 12367 Click to see CCCCCCCC(C)O 144.25 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Undecanol 15448 Click to see CCCCCCCCCC(C)O 172.31 unknown https://doi.org/10.1080/10412905.1991.9697956
Lauryl Alcohol 8193 Click to see 186.33 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
P-Cymene 7463 Click to see 134.22 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
Limonene, (+/-)- 22311 Click to see CC1=CCC(CC1)C(=C)C 136.23 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Monocyclic monoterpenoids
(3S,4S)-4-Ethenyl-4-methyl-3-(prop-1-en-2-yl)cyclohexene 12310053 Click to see 162.27 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
Caryophyllene 5281515 Click to see CC1=CCCC(=C)C2CC(C2CC1)(C)C 204.35 unknown https://doi.org/10.1080/10412905.1991.9697956
Humulene 5281520 Click to see 204.35 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Elemane sesquiterpenoids
2-(4-Ethenyl-4-methyl-3-(prop-1-en-2-yl)cyclohexyl)propan-2-ol 547972 Click to see 222.37 unknown https://doi.org/10.1080/10412905.1991.9697956
Elemol 92138 Click to see 222.37 unknown https://doi.org/10.1080/10412905.1991.9697956
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
Angustifolin 21575185 Click to see CC12CCCC3(C1C(OC2)OC)COC(=O)C45C3C(CC(C4)C(=C)C5=O)O 376.40 unknown https://doi.org/10.1016/S0031-9422(00)84991-2
https://doi.org/10.1016/0031-9422(86)80093-0
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes
Nonanal 31289 Click to see CCCCCCCCC=O 142.24 unknown https://doi.org/10.1080/10412905.1991.9697956
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Ketones
10-Methylundecan-2-one 528743 Click to see 184.32 unknown https://doi.org/10.1080/10412905.1991.9697956
11-Methyldodecan-2-one 21427346 Click to see CC(C)CCCCCCCCC(=O)C 198.34 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Decanone 12741 Click to see 156.26 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Dodecanone 22556 Click to see 184.32 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Nonanone 13187 Click to see 142.24 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Octanone 8093 Click to see 128.21 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Tridecanone 11622 Click to see 198.34 unknown https://doi.org/10.1080/10412905.1991.9697956
2-Undecanone 8163 Click to see 170.29 unknown https://doi.org/10.1080/10412905.1991.9697956
7-Methyloctan-2-one 519008 Click to see 142.24 unknown https://doi.org/10.1080/10412905.1991.9697956
8-Methylnonan-2-one 528744 Click to see CC(C)CCCCCC(=O)C 156.26 unknown https://doi.org/10.1080/10412905.1991.9697956
9-Methyldecan-2-one 528742 Click to see 170.29 unknown https://doi.org/10.1080/10412905.1991.9697956
> Organoheterocyclic compounds / Benzodioxoles
(2S)-6-(1,3-benzodioxol-5-yl)hexan-2-ol 163014567 Click to see 222.28 unknown https://doi.org/10.1016/0031-9422(86)80093-0
2-Hexanone, 6-(3,4-methylenedioxyphenyl) 529777 Click to see CC(=O)CCCCC1=CC2=C(C=C1)OCO2 220.26 unknown https://doi.org/10.1016/0031-9422(86)80093-0
2-Octanone, 8-(3,4-methylenedioxyphenyl) 529778 Click to see CC(=O)CCCCCCC1=CC2=C(C=C1)OCO2 248.32 unknown https://doi.org/10.1016/0031-9422(86)80093-0
3',4'-(Methylenedioxy)acetophenone 76622 Click to see CC(=O)C1=CC2=C(C=C1)OCO2 164.16 unknown https://doi.org/10.1016/0031-9422(86)80093-0
moskachan C 44558951 Click to see CC(CCCCC1=CC2=C(C=C1)OCO2)O 222.28 unknown https://doi.org/10.1016/0031-9422(86)80093-0
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
Graveoline 353825 Click to see 279.29 unknown https://doi.org/10.1016/0031-9422(73)80445-5
https://doi.org/10.1016/S0031-9422(00)84991-2
> Phenylpropanoids and polyketides / Coumarins and derivatives
Scoparone 8417 Click to see 206.19 unknown https://doi.org/10.1016/S0031-9422(00)84991-2
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
7-Hydroxy-3-(2-methylbut-3-en-2-yl)chromen-2-one 5363192 Click to see 230.26 unknown https://doi.org/10.1016/S0031-9422(00)84991-2
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Quercetin 5280343 Click to see 302.23 unknown https://doi.org/10.1515/ZNC-1983-1-226

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