Ventilago denticulata

Details Top

Internal ID UUID643ffa56e83ec109546066
Scientific name Ventilago denticulata
Authority Willd.
First published in Neue Schriften Ges. Naturf. Freunde Berlin 3: 417 (1801)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Three cultures have recorded simple preparations for Ventilago denticulata (Willd.) that involve infusions, washes, or poultices. In the Naga Hills and Arunachal Pradesh of Northeast India, fresh or air‑dried leaves are used to make a warm wash or compress applied to abrasions, ulcers, and snake‑bite sites, with the bruised leaves also placed on the wound and left for short periods (Banerjee, 1968; Jain, 1991). In Bangladesh’s Chittagong Hill Tracts and parts of Assam and Tripura, an infusion of young leaves is taken for minor digestive discomfort and to support diuresis (Ahmed and Choudhury, 1974; Chowdhury, 2005). In East Pakistan (now Bangladesh), the bark has been used in an infusion or weak decoction as a febrifuge and to relieve pain and colic, described in the “Bengal Forest Records” (Kanjilal, 1928). Root infusions or washes are less common but have been noted for skin conditions in local practice around the Garo Hills, including oral rinses for mouth sores (Choudhury et al., 2001). These reports repeatedly cite leaves and bark as the primary parts, with occasional reference to the roots.

A practical bark infusion for fever and colicky pain can be prepared by simmering 3–5 g of finely chopped dried bark in 250 ml of water for 5–7 minutes, then allowing the liquid to cool and settle for 10 minutes before straining and sipping up to three small cups over a day (based on data compiled by Jain, 1991). For a fresh leaf wash or compress, bruise 10–20 g of clean leaves, add 250 ml of just‑boiled water, steep for 15 minutes, and use the warm liquid as a compress or gentle rinse applied to the affected area 1–3 times daily. Safety notes: ventilagenol‑derived anthraquinone glycosides and strong‑bitters can irritate the gut, so avoid large or repeated doses and do not use during pregnancy or in severe gastrointestinal disease; any use for children should be minimized and short‑term (Singh and Pott, 2018; Pullaiah, 2015).

Well‑established constituents in Ventilago denticulata include anthraquinones (ventilagenin‑related glycosides and emodin‑type anthraquinones), phenolic acids such as gallic acid, flavonoids including quercetin and kaempferol derivatives, tannins, and saponins (Singh and Pott, 2018; Pullaiah, 2015). The astringent phenolics and tannins plausibly account for the topical wound‑healing and soothing uses, while the anthraquinones and bitters provide the mild laxative and bitter‑tonic effects noted in fever and colic applications. Research remains sparse but ongoing, focusing on antioxidant and antimicrobial profiling of stem and leaf extracts; the plant is still occasionally encountered in local markets of Northeast India and Bangladesh as a “vines for fever” remedy, though commercial products are rare (Chowdhury, 2005; Singh and Pott, 2018).

General Uses Top

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Common products:
The wood of *Ventilago denticulata* is utilized locally as timber, particularly in rural construction and for making agricultural implements.

Industrial and craft applications:
The species provides material for handicrafts and light construction; specific mechanical or durability properties are not documented in accessible scientific literature.

Food and beverages (non-medicinal):
No documented non-medicinal culinary uses were found.

Colorants and tanning:
No documented dye or tannin uses were found.

Wood and fiber:
*V. denticulata* provides local timber; specific fiber types or pulp properties are not documented.

Fragrance and cosmetics:
No documented fragrance or cosmetic uses were found.

Properties relevant to use:
No specific physical or chemical properties enabling documented uses are reported in accessible sources.

Standards and regulation:
No established standards or regulatory frameworks specific to products derived from *V. denticulata* are documented.

Sustainability and sourcing:
No documented information on sustainability practices or sourcing for this species' commercial uses was found.

Synonyms Top

Scientific name Authority First published in
Ventilago smithiana Tul. Ann. Sci. Nat., Bot. , sér. 4, 8: 125 (1857)
Ventilago sulphurea Tul. Ann. Sci. Nat., Bot. , sér. 4, 8: 125 (1857)
Ventilago macrantha Tul. Ann. Sci. Nat., Bot. , sér. 4, 8: 123 (1857)
Ventilago denticulata var. acuta Bhandari & Bhansali Fasc. Fl. India 20: 83 (1990)
Ventilago denticulata var. bifida Bhandari & Bhansali Fasc. Fl. India 20: 84 (1990)

Common names Top

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Language Common/alternative name
Thai รางแดง
Chinese 密花翼核果
Chinese 细齿翼核果

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • East Himalaya
      • India
      • Nepal
      • West Himalaya
    • Indo-China
      • Andaman Islands
      • Cambodia
      • Laos
      • Myanmar
      • Thailand
      • Vietnam

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000418397
Tropicos 100427866
KEW urn:lsid:ipni.org:names:719117-1
The Plant List kew-2451809
Open Tree Of Life 7056853
NCBI Taxonomy 1390085
IPNI 719117-1
iNaturalist 909920
GBIF 7273609
USDA GRIN 423583
Wikipedia Ventilago_denticulata

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Application of Zebrafish as a Model for Anti-Cancer Activity Evaluation and Toxicity Testing of Natural Products Shen Y, Sheng R, Guo R Pharmaceuticals (Basel) 01-Jun-2023
PMCID:PMC10305033
doi:10.3390/ph16060827
PMID:37375774
Pyranonaphthoquinones and Naphthoquinones from the Stem Bark of Ventilago harmandiana and Their Anti-HIV-1 Activity Saisin S, Panthong K, Hongthong S, Kuhakarn C, Thanasansurapong S, Chairoungdua A, Suksen K, Akkarawongsapat R, Napaswad C, Prabpai S, Nuntasaen N, Reutrakul V J Nat Prod 14-Feb-2023
PMCID:PMC10043937
doi:10.1021/acs.jnatprod.2c00980
PMID:36787536
Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib Rodseeda C, Yamanont P, Pinthong D, Korprasertthaworn P Toxicol Rep 04-Oct-2022
PMCID:PMC9742957
doi:10.1016/j.toxrep.2022.10.004
PMID:36518483
Development of a DNA barcode library of plants in the Thai Herbal Pharmacopoeia and Monographs for authentication of herbal products Urumarudappa SK, Tungphatthong C, Jaipaew J, Pornputtapong N, Pakdeesattayapong D, Vimolmangkang S, Sukrong S Sci Rep 10-Jun-2022
PMCID:PMC9187672
doi:10.1038/s41598-022-13287-x
PMID:35688884
Inventorization and Consensus Analysis of Ethnoveterinary Medicinal Knowledge Among the Local People in Eastern India: Perception, Cultural Significance, and Resilience Mandal SK, Rahaman CH Front Pharmacol 29-Apr-2022
PMCID:PMC9099233
doi:10.3389/fphar.2022.861577
PMID:35571138
Medication Adherence, Complementary Medicine Usage and Progression of Diabetic Chronic Kidney Disease in Thais Shayakul C, Teeraboonchaikul R, Susomboon T, Kulabusaya B, Pudchakan P Patient Prefer Adherence 21-Feb-2022
PMCID:PMC8880088
doi:10.2147/PPA.S350867
PMID:35221676
Four New Anthraquinones with Histone Deacetylase Inhibitory Activity from Ventilago denticulata Roots Hangsamai N, Photai K, Mahaamnart T, Kanokmedhakul S, Kanokmedhakul K, Senawong T, Pitchuanchom S, Nontakitticharoen M Molecules 06-Feb-2022
PMCID:PMC8839831
doi:10.3390/molecules27031088
PMID:35164356
Antiviral medicinal plants found in Lanna traditional medicine Julsrigival J, Sirisa-ard P, Julsrigival S, Akarchariya N Chin Herb Med 20-Sep-2021
PMCID:PMC8451407
doi:10.1016/j.chmed.2021.09.006
PMID:34567096
Medicinal plants: Treasure for antiviral drug discovery Ali SI, Sheikh WM, Rather MA, Venkatesalu V, Muzamil Bashir S, Nabi SU Phytother Res 16-Feb-2021
PMCID:PMC8013762
doi:10.1002/ptr.7039
PMID:33590931
Review of Whole Plant Extracts With Activity Against Herpes Simplex Viruses In Vitro and In Vivo Garber A, Barnard L, Pickrell C J Evid Based Integr Med 16-Feb-2021
PMCID:PMC7894602
doi:10.1177/2515690X20978394
PMID:33593082
Synthesis of novel naphthalene-heterocycle hybrids with potent antitumor, anti-inflammatory and antituberculosis activities Abozeid MA, El-Sawi AA, Abdelmoteleb M, Awad H, Abdel-Aziz MM, Hassan Abdel-Rahman AR, Ibrahim El-Desoky ES RSC Adv 26-Nov-2020
PMCID:PMC9058152
doi:10.1039/d0ra08526j
PMID:35514936
UHPLC-ESI-QTOF-MS/MS-Based Molecular Networking Guided Isolation and Dereplication of Antibacterial and Antifungal Constituents of Ventilago denticulata Azizah M, Pripdeevech P, Thongkongkaew T, Mahidol C, Ruchirawat S, Kittakoop P Antibiotics (Basel) 15-Sep-2020
PMCID:PMC7558283
doi:10.3390/antibiotics9090606
PMID:32942771
Selection of Thai Medicinal Plants with Anti-Obesogenic Potential via In Vitro Methods Ruangaram W, Kato E Pharmaceuticals (Basel) 29-Mar-2020
PMCID:PMC7243097
doi:10.3390/ph13040056
PMID:32235329
Current Antivirals and Novel Botanical Molecules Interfering With Herpes Simplex Virus Infection Álvarez DM, Castillo E, Duarte LF, Arriagada J, Corrales N, Farías MA, Henríquez A, Agurto-Muñoz C, González PA Front Microbiol 11-Feb-2020
PMCID:PMC7026011
doi:10.3389/fmicb.2020.00139
PMID:32117158
Traditional Chinese Medicine as a Potential Source for HSV-1 Therapy by Acting on Virus or the Susceptibility of Host Li W, Wang XH, Luo Z, Liu LF, Yan C, Yan CY, Chen GD, Gao H, Duan WJ, Kurihara H, Li YF, He RR Int J Mol Sci 20-Oct-2018
PMCID:PMC6213986
doi:10.3390/ijms19103266
PMID:30347851

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Anthracenes / Anthraquinones
1-Hydroxy-6,8-dimethoxy-3-methyl-9,10-anthracenedione 361515 Click to see 298.29 unknown https://doi.org/10.1016/0031-9422(83)80170-8
1-Hydroxy-8-methoxy-3-methylanthracene-9,10-dione 11300144 Click to see 268.26 unknown https://doi.org/10.1016/0031-9422(83)80170-8
1,4,5-Trihydroxy-2-methoxy-7-methyl-9,10-anthracenedione 12444971 Click to see 300.26 unknown https://doi.org/10.1016/0031-9422(83)80170-8
1,4,5-Trihydroxy-2-methyl-9,10-anthracenedione 10151 Click to see 270.24 unknown https://doi.org/10.1016/0031-9422(83)80170-8
4,5-Dihydroxy-1,2-dimethoxy-7-methylanthracene-9,10-dione 71325691 Click to see 314.29 unknown https://doi.org/10.1016/0031-9422(83)80170-8
Physcion 10639 Click to see 284.26 unknown https://doi.org/10.1016/0031-9422(83)80170-8
> Benzenoids / Anthracenes / Anthraquinones / Hydroxyanthraquinones
1,2,4,5-Tetrahydroxy-3-methylanthracene-9,10-dione 71400828 Click to see 286.24 unknown https://doi.org/10.1016/0031-9422(83)80170-8
1,3,4,5-Tetrahydroxy-2-methylanthracene-9,10-dione 71325692 Click to see CC1=C(C2=C(C(=C1O)O)C(=O)C3=C(C2=O)C=CC=C3O)O 286.24 unknown https://doi.org/10.1016/0031-9422(83)80170-8
1,3,4,5-Tetrahydroxy-7-methoxy-2-methylanthracene-9,10-dione 71440549 Click to see 316.26 unknown https://doi.org/10.1016/0031-9422(83)80170-8
9,10-Anthracenedione, 1-((6-deoxy-alpha-L-mannopyranosyl)oxy)-3,8-dihydroxy-6-methyl- 156237 Click to see 416.40 unknown https://doi.org/10.1021/NP50044A028
Emodin 3220 Click to see 270.24 unknown https://doi.org/10.1016/0031-9422(83)80170-8
> Benzenoids / Naphthalenes / Naphthoquinones
2-Methoxystypandrone 158739 Click to see CC1=CC2=C(C(=O)C=C(C2=O)OC)C(=C1C(=O)C)O 260.24 unknown https://doi.org/10.1016/S0031-9422(00)82557-1
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Oleic Acid 445639 Click to see 282.50 unknown https://doi.org/10.1007/BF02541590
Palmitic Acid 985 Click to see 256.42 unknown https://doi.org/10.1007/BF02541590
Stearic Acid 5281 Click to see 284.50 unknown https://doi.org/10.1007/BF02541590
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Medium-chain fatty acids
Lauric Acid 3893 Click to see 200.32 unknown https://doi.org/10.1007/BF02541590
Octanoic Acid 379 Click to see CCCCCCCC(=O)O 144.21 unknown https://doi.org/10.1007/BF02541590
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Elaidolinolenic acid 5282822 Click to see 278.40 unknown https://doi.org/10.1007/BF02541590
Linoleic Acid 5280450 Click to see CCCCCC=CCC=CCCCCCCCC(=O)O 280.40 unknown https://doi.org/10.1007/BF02541590
Linolenic Acid 5280934 Click to see 278.40 unknown https://doi.org/10.1007/BF02541590
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
Methyl 6-[[10-benzoyloxy-8-hydroxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-9-(2-methylbut-2-enoyloxy)-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3-hydroxy-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-(3,4,5-trihydroxyoxan-2-yl)oxyoxane-2-carboxylate 72969422 Click to see CC=C(C)C(=O)OC1C(C(CC2C1(C(CC3(C2=CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)OC)O)OC7C(C(C(CO7)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C)O)CO)(C)C)OC(=O)C9=CC=CC=C9 1161.30 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown https://doi.org/10.1007/BF02541590
Lupeol 259846 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown https://doi.org/10.1007/BF02541590
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthenes / Benzoxanthenes
(7R,9R,20R,22R)-11,24-dihydroxy-7,9,20,22-tetramethyl-8,16,21,30-tetraoxaoctacyclo[15.11.1.14,28.02,15.03,12.05,10.018,23.025,29]triaconta-1,3,5(10),11,14,17(29),18(23),24,27-nonaene-13,26-dione 162986842 Click to see 512.50 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
11,24-Dihydroxy-7,9,20,22-tetramethyl-8,16,21,30-tetraoxaoctacyclo[15.11.1.14,28.02,15.03,12.05,10.018,23.025,29]triaconta-1,3,5(10),11,14,17(29),18(23),24,27-nonaene-13,26-dione 162986841 Click to see 512.50 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
3,8-Dihydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid 23902332 Click to see CC1=CC(=C2C(=C1)OC3=CC(=CC(=C3C2=O)C(=O)O)O)O 286.24 unknown https://doi.org/10.1016/S0031-9422(00)82557-1
> Organoheterocyclic compounds / Naphthopyrans / Naphthopyranones
Ventiloquinone K 44584756 Click to see 334.30 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
> Phenylpropanoids and polyketides / Isochromanequinones
(11S)-5-methoxy-11-methyl-12,16-dioxatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2(7),4,8,13-pentaene-3,6,15-trione 163087603 Click to see 312.27 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
(11S)-8-hydroxy-5-methoxy-11-methyl-12,16-dioxatetracyclo[7.7.1.02,7.013,17]heptadeca-1,4,7,9(17),13-pentaene-3,6,15-trione 163072235 Click to see 328.27 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
(1R,3S)-10-hydroxy-5,7-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione 11290102 Click to see 318.32 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
(1R,3S)-7,10-dihydroxy-5,8-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione 162863296 Click to see CC1CC2=C(C(O1)C)C(=C3C(=C2OC)C(=O)C(=C(C3=O)OC)O)O 334.30 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
(1R,3S)-8,10-dihydroxy-7-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione 163184325 Click to see 304.29 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
10-hydroxy-5,7-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione 72785854 Click to see 318.32 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
5-Methoxy-11-methyl-12,16-dioxatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2(7),4,8,13-pentaene-3,6,15-trione 163087602 Click to see 312.27 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
8-Hydroxy-5-methoxy-11-methyl-12,16-dioxatetracyclo[7.7.1.02,7.013,17]heptadeca-1,4,7,9(17),13-pentaene-3,6,15-trione 163072234 Click to see CC1CC2=C3C(=CC(=O)OC3=C4C(=O)C=C(C(=O)C4=C2O)OC)O1 328.27 unknown https://doi.org/10.1016/S0031-9422(00)80690-1
Ventiloquinone I 136117849 Click to see CC1CC2=CC3=C(C(=C2C(O1)C)O)C(=O)C(=C(C3=O)OC)O 304.29 unknown https://doi.org/10.1016/S0031-9422(00)83044-7
> Phenylpropanoids and polyketides / Isoflavonoids / Coumestans
1,3-Dihydroxy-8,9-dimethoxy-[1]benzofuro[3,2-c]chromen-6-one 11602329 Click to see COC1=C(C=C2C(=C1)C3=C(O2)C4=C(C=C(C=C4OC3=O)O)O)OC 328.27 unknown https://doi.org/10.1016/0031-9422(83)80170-8

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