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Actaea podocarpa

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID64400736c3733834203390
Scientific name Actaea podocarpa
Authority DC.
First published in Syst. Nat. 1: 282 (1817)

Ethnobotanical Use Top

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General Uses Top

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Synonyms Top

Scientific name Authority First published in
Thalictrodes americanum (Michx.) Kuntze Revis. Gen. Pl. 1: 4 (1891)
Actaea americana (Michx.) Prantl Bot. Jahrb. Syst. 9(3): 246. 1887 [30 Dec 1887]
Actaea pentacarpa Michx. ex Torr. & A.Gray Fl. N. Amer. 1: 39 (1838)
Actaea pentagyna Walter Fl. Carol. : 151 (1788)
Cimicifuga americana Michx. Fl. Bor.-Amer. 1: 316 (1803)
Cimicifuga cordifolia Pursh Fl. Amer. Sept. (Pursh) 2: 373. 1813 [Dec 1813]
Cimicifuga podocarpa (DC.) Elliott Sketch Bot. S. Carolina 2: 16 (1821)
Thalictrodes cordifolia (DC.) Kuntze Revis. Gen. Pl. 1: 4. 1891 [5 Nov 1891]

Common names Top

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Language Common/alternative name
English mountain bugbane

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Expose seeds to natural outdoor winter conditions for 3 months, then gradually increase light and temperature in the spring.
seedlings must be grown at less than 20° and can overwinter at -20°, prick out while small, seed is viable for at least 6m

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • North-central U.S.A.
      • Illinois
    • Northeastern U.S.A.
      • Pennsylvania
      • West Virginia
    • Southeastern U.S.A.
      • Georgia
      • Kentucky
      • Maryland
      • North Carolina
      • South Carolina
      • Tennessee
      • Virginia

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000519110
USDA Plants ACPO11
Tropicos 50123301
KEW urn:lsid:ipni.org:names:1191192-2
The Plant List kew-2620563
Missouri Botanical Garden 291897
Open Tree Of Life 170535
NCBI Taxonomy 46991
Nature Serve 2.144206
IPNI 1191192-2
iNaturalist 116343
GBIF 5616574
Freebase /m/0_1d4lv
EPPO CIMRC
EOL 594790
USDA GRIN 429253
Wikipedia Actaea_podocarpa

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Investigation of market herbal products regulated under different categories: How can HPTLC help to detect quality problems? Frommenwiler DA, Reich E, Sharaf MH, Cañigueral S, Etheridge CJ Front Pharmacol 08-Aug-2022
PMCID:PMC9393483
doi:10.3389/fphar.2022.925298
PMID:36003516
Benefits of Black Cohosh (Cimicifuga racemosa) for Women Health: An Up-Close and In-Depth Review Mohapatra S, Iqubal A, Ansari MJ, Jan B, Zahiruddin S, Mirza MA, Ahmad S, Iqbal Z Pharmaceuticals (Basel) 23-Feb-2022
PMCID:PMC8953734
doi:10.3390/ph15030278
PMID:35337076
Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity Dembitsky VM, Ermolenko E, Savidov N, Gloriozova TA, Poroikov VV Molecules 28-Jan-2021
PMCID:PMC7865715
doi:10.3390/molecules26030686
PMID:33525706
Differentiation of Actaea Species by NMR Metabolomics Analysis Imai A, Lankin DC, Gödecke T, Chen SN, Pauli GF Fitoterapia 15-Jul-2020
PMCID:PMC7572815
doi:10.1016/j.fitote.2020.104686
PMID:32679162
NMR based quantitation of cycloartane triterpenes in black cohosh extracts Imai A, Lankin D, Gödecke T, Chen SN, Pauli GF Fitoterapia 27-Dec-2019
PMCID:PMC7066989
doi:10.1016/j.fitote.2019.104467
PMID:31887327
Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV Toxicol Sci 27-Aug-2019
PMCID:PMC6876258
doi:10.1093/toxsci/kfz189
PMID:31504990
Black Cohosh Extracts and Powders Induce Micronuclei, a Biomarker of Genetic Damage, in Human Cells Smith-Roe SL, Swartz CD, Shepard KG, Bryce SM, Dertinger SD, Waidyanatha S, Kissling GE, Auerbach SS, Witt KL Environ Mol Mutagen 18-Apr-2018
PMCID:PMC6031461
doi:10.1002/em.22182
PMID:29668046
Herbal and Dietary Supplement Induced Liver Injury de Boer YS, Sherker AH Clin Liver Dis 14-Oct-2016
PMCID:PMC5117680
doi:10.1016/j.cld.2016.08.010
PMID:27842768
Comparison of Flow Injection MS, NMR, and DNA Sequencing: Methods for Identification and Authentication of Black Cohosh (Actaea racemosa) Harnly J, Chen P, Sun J, Huang H, Colson KL, Yuk J, McCoy JA, Harbaugh Reynaud DT, Harrington PB, Fletcher EJ Planta Med 21-Dec-2015
PMCID:PMC4835812
doi:10.1055/s-0035-1558113
PMID:26692457
Fcγ and Complement Receptors and Complement Proteins in Neutrophil Activation in Rheumatoid Arthritis: Contribution to Pathogenesis and Progression and Modulation by Natural Products Paoliello-Paschoalato AB, Marchi LF, de Andrade MF, Kabeya LM, Donadi EA, Lucisano-Valim YM Evid Based Complement Alternat Med 05-Aug-2015
PMCID:PMC4540990
doi:10.1155/2015/429878
PMID:26346244
Serum proteomic, peptidomic and metabolomic profiles in myasthenia gravis patients during treatment with Qiangji Jianli Fang Wang C, Lu Y, Chen Z, Liu X, Lin H, Zhao H, Chen J, Kwan Y, Ngai S Chin Med 28-Jul-2012
PMCID:PMC3464942
doi:10.1186/1749-8546-7-16
PMID:22838635
High-throughput screening and mechanism-based evaluation of estrogenic botanical extracts Overk CR, Yao P, Chen S, Deng S, Imai A, Main M, Schinkovitz A, Farnsworth NR, Pauli GF, Bolton JL Comb Chem High Throughput Screen 01-May-2008
PMCID:PMC3219440
doi:10.2174/138620708784246022
PMID:18473738
Detection of Actaea racemosa Adulteration by Thin-Layer Chromatography and Combined Thin-Layer Chromatography-Bioluminescence Verbitski SM, Gourdin GT, Ikenouye LM, McChesney JD, Hildreth J J AOAC Int 01-Mar-2008
PMCID:PMC4115334
PMID:18476337
9,10-seco-9,19-Cyclolanostane arabinosides from the roots of Actaea podocarpa. Ali Z, Khan SI, Fronczek FR, Khan IA Phytochemistry 01-Feb-2007
doi:10.1016/J.PHYTOCHEM.2006.10.021
PMID:17141286
Podocarpaside, a triterpenoid possessing a new backbone from Actaea podocarpa. Ali Z, Khan SI, Ferreira D, Khan IA Org Lett 23-Nov-2006
doi:10.1021/OL062212S
PMID:17107064

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
Myrcene 31253 Click to see 136.23 unknown https://doi.org/10.1016/0305-1978(87)90058-5
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(1R,5R,6R,8R,9S,10R,12S,15S)-8-hydroxy-6-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-5,9,14,14-tetramethyl-15-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-19,20-dioxapentacyclo[10.6.2.02,10.05,9.013,18]icosa-2,13(18)-dien-7-one 139071968 Click to see 648.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(2R,3S,6S,8R,11R,12S,13R,15R,16R)-2,13-dihydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 16110016 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)C(C2(C1(CC=C3C2CCC4C(C3O)CCC(C4(C)C)OC5C(C(C(CO5)O)O)O)C)C)O 636.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(2R,3S,6S,8R,11S,12S,15R,16R)-2-hydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 16110011 Click to see 620.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(2S,6S,9R,11R,12S,13R,15R,16R)-2,9,13-trihydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),3(8)-dien-14-one 16110013 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)C(C2(C1(CC=C3C2CC(C4=C(C3O)CCC(C4(C)C)OC5C(C(C(CO5)O)O)O)O)C)C)O 650.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(3S,6S,8S,11R,12S,15R,16R)-3-hydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 16110012 Click to see 620.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(4S,6S,11R,12S,15R,16R)-4-hydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),3(8)-dien-14-one 16110015 Click to see 618.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(6S,11R,12S,13R,15R,16R)-13-hydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),2,8-trien-14-one 16110014 Click to see 616.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(6S,11R,12S,15R,16R)-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),3(8)-dien-14-one 163103850 Click to see 602.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
(6S,8R,11R,12S,13R,15R,16R)-13-hydroxy-15-[(2R)-6-hydroxy-6-methyl-4-oxoheptan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),2-dien-14-one 16110017 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)C(C2(C1(CC=C3C2CCC4C(=C3)CCC(C4(C)C)OC5C(C(C(CO5)O)O)O)C)C)O 618.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
13-Hydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),2-dien-14-one 162930921 Click to see 618.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
13-Hydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),2,8-trien-14-one 162894436 Click to see 616.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
2-Hydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 163038700 Click to see 620.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
2,13-Dihydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 162886394 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)C(C2(C1(CC=C3C2CCC4C(C3O)CCC(C4(C)C)OC5C(C(C(CO5)O)O)O)C)C)O 636.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
2,9,13-Trihydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),3(8)-dien-14-one 162888835 Click to see 650.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
3-Hydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadec-1(18)-en-14-one 162948844 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)CC2(C1(CC=C3C2CCC4C(C(CCC4(C3)O)OC5C(C(C(CO5)O)O)O)(C)C)C)C 620.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
4-Hydroxy-15-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-7,7,12,16-tetramethyl-6-(3,4,5-trihydroxyoxan-2-yl)oxytetracyclo[9.7.0.03,8.012,16]octadeca-1(18),3(8)-dien-14-one 162979478 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)CC2(C1(CC=C3C2CCC4=C(C3)C(CC(C4(C)C)OC5C(C(C(CO5)O)O)O)O)C)C 618.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.10.021
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides
11-(hydroxymethyl)-17-(6-hydroxy-6-methyl-4-oxoheptan-2-yl)-4,4,13,14-tetramethyl-3-(3,4,5-trihydroxyoxan-2-yl)oxy-2,3,5,6,7,8,11,12,15,17-decahydro-1H-cyclopenta[a]phenanthren-16-one 73242137 Click to see 620.80 unknown https://doi.org/10.1021/OL062212S
Podocarpaside 16094884 Click to see CC(CC(=O)CC(C)(C)O)C1C(=O)CC2(C1(CC(C3=C4CCC(C(C4CCC32)(C)C)OC5C(C(C(CO5)O)O)O)CO)C)C 620.80 unknown https://doi.org/10.1021/OL062212S

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