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Details Top

Internal ID UUID644013b5b251d104845150
Scientific name Corydalis saxicola
Authority Bunting
First published in Baileya 13: 172 (1966)

Description Top

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Synonyms Top

Scientific name Authority First published in
Corydalis thalictrifolia Franch. J. Bot. (Morot) viii. (1894) 291.

Common names Top

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Language Common/alternative name
Chinese 土黄连
Chinese 黄连
Chinese 岩黄连
Chinese 石生黄堇
Chinese 岩连
Chinese 菊花黄连
Chinese 鸡爪连
Chinese 石生黃堇

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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Germination/Propagation Top

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Expose seeds to natural outdoor winter conditions for 3 months, then gradually increase light and temperature in the spring.
Sow seeds immediately as their viability decreases rapidly, or they best germinate when fresh. If stored, seeds might need temperature cycling and patience to germinate.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • China Southeast

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000622851
Tropicos 24000769
KEW urn:lsid:ipni.org:names:672482-1
The Plant List kew-2739229
Open Tree Of Life 345836
NCBI Taxonomy 282776
IPNI 672482-1
GBIF 5531204
EOL 5473936

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The role of PI3k/AKT signaling pathway in attenuating liver fibrosis: a comprehensive review Shamsan E, Almezgagi M, Gamah M, Khan N, Qasem A, Chuanchuan L, Haining F Front Med (Lausanne) 25-Mar-2024
PMCID:PMC10999701
doi:10.3389/fmed.2024.1389329
PMID:38590313
RNA editing events and expression profiles of mitochondrial protein-coding genes in the endemic and endangered medicinal plant, Corydalis saxicola Li C, Liu H, Qin M, Tan YJ, Ou XL, Chen XY, Wei Y, Zhang ZJ, Lei M Front Plant Sci 06-Feb-2024
PMCID:PMC10876856
doi:10.3389/fpls.2024.1332460
PMID:38379941
Mechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways Ren G, Bai C, Yi S, Cong Q, Zhu Y J Innate Immun 21-Dec-2023
PMCID:PMC10783892
doi:10.1159/000535524
PMID:38128497
Review of the correlation between Chinese medicine and intestinal microbiota on the efficacy of diabetes mellitus Su M, Hu R, Tang T, Tang W, Huang C Front Endocrinol (Lausanne) 25-Jan-2023
PMCID:PMC9905712
doi:10.3389/fendo.2022.1085092
PMID:36760813
Corydalis saxicola Bunting: A Review of Its Traditional Uses, Phytochemistry, Pharmacology, and Clinical Applications Qin F, Chen Y, Wang FF, Tang SQ, Fang YL Int J Mol Sci 13-Jan-2023
PMCID:PMC9864617
doi:10.3390/ijms24021626
PMID:36675133
Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight Sharma D, Sharma N, Manchanda N, Prasad SK, Sharma PC, Thakur VK, Rahman MM, Dhobi M Biomolecules 21-Dec-2022
PMCID:PMC9856122
doi:10.3390/biom13010017
PMID:36671402
Role of bioactive compounds in the treatment of hepatitis: A review Roy A, Roy M, Gacem A, Datta S, Zeyaullah M, Muzammil K, Farghaly TA, Abdellattif MH, Yadav KK, Simal-Gandara J Front Pharmacol 21-Dec-2022
PMCID:PMC9810990
doi:10.3389/fphar.2022.1051751
PMID:36618936
Investigation of the Therapeutic Effect of Total Alkaloids of Corydalis saxicola Bunting on CCl4-Induced Liver Fibrosis in Rats by LC/MS-Based Metabolomics Analysis and Network Pharmacology Wang Q, Luo Z, Li D, Qin J, Pan Z, Guo B, Deng L, Nong Y, Huang Z, He Y, Guo H, Zhu D, Liang Y, Su Z Metabolites 21-Dec-2022
PMCID:PMC9866371
doi:10.3390/metabo13010009
PMID:36676934
Extensive reorganization of the chloroplast genome of Corydalis platycarpa: A comparative analysis of their organization and evolution with other Corydalis plastomes Raman G, Nam GH, Park S Front Plant Sci 09-Dec-2022
PMCID:PMC10115153
doi:10.3389/fpls.2022.1043740
PMID:37090468
Effects of Dietary Macleaya cordata Extract on Growth Performance, Biochemical Indices, and Intestinal Microbiota of Yellow-Feathered Broilers Subjected to Chronic Heat Stress Wang M, Zhang J, Huang X, Liu Y, Zeng J Animals (Basel) 26-Aug-2022
PMCID:PMC9454434
doi:10.3390/ani12172197
PMID:36077916
The Traditional Uses, Phytochemistry, Pharmacokinetics, Pharmacology, Toxicity, and Applications of Corydalis saxicola Bunting: A Review Guo Y, Zhao L, Chang B, Yu J, Bao J, Yao Q, Luo J Front Pharmacol 16-Feb-2022
PMCID:PMC8890665
doi:10.3389/fphar.2022.822792
PMID:35250571
The anti-hepatitis B virus and anti-hepatotoxic efficacies of solanopubamine, a rare alkaloid from Solanum schimperianum Parvez MK, Al-Dosari MS, Rehman MT, Al-Rehaily AJ, Alqahtani AS, Alajmi MF Saudi Pharm J 07-Feb-2022
PMCID:PMC9068741
doi:10.1016/j.jsps.2022.02.001
PMID:35527834
Application Potential of Plant-Derived Medicines in Prevention and Treatment of Platinum-Induced Peripheral Neurotoxicity Xu X, Jia L, Ma X, Li H, Sun C Front Pharmacol 13-Jan-2022
PMCID:PMC8793340
doi:10.3389/fphar.2021.792331
PMID:35095502
Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism Yang L, Bi L, Jin L, Wang Y, Li Y, Li Z, He W, Cui H, Miao J, Wang L Front Pharmacol 24-Nov-2021
PMCID:PMC8651620
doi:10.3389/fphar.2021.772635
PMID:34899328
Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer’s Disease Cahlíková L, Vrabec R, Pidaný F, Peřinová R, Maafi N, Mamun AA, Ritomská A, Wijaya V, Blunden G Molecules 29-Aug-2021
PMCID:PMC8434202
doi:10.3390/molecules26175240
PMID:34500673

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Benzophenanthridine alkaloids / Dihydrobenzophenanthridine alkaloids
(+/-)-6-Acetonyldihydrosanguinarine 181538 Click to see CC(=O)CC1C2=C(C=CC3=C2OCO3)C4=C(N1C)C5=CC6=C(C=C5C=C4)OCO6 389.40 unknown https://doi.org/10.1055/S-2007-981549
6-Acetonyl 5,6-dihydrosanguinarine 71745004 Click to see CC(=O)CC1C2=C(C=CC3=C2OCO3)C4=C(N1C)C5=CC6=C(C=C5C=C4)OCO6 389.40 unknown https://doi.org/10.1055/S-2007-981549
Dihydrochelerythrine 485077 Click to see CN1CC2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5 349.40 unknown https://doi.org/10.1055/S-2007-981549
Dihydrosanguinarine 124069 Click to see CN1CC2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6 333.30 unknown https://doi.org/10.1055/S-2007-981549
> Alkaloids and derivatives / Phthalide isoquinolines
6-(6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-E][1,3]benzodioxol-8(6H)-one 2376 Click to see CN1CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 367.40 unknown https://doi.org/10.1055/S-2007-981549
Adlumidine 120734 Click to see CN1CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 367.40 unknown https://doi.org/10.1055/S-2007-981549
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
(-)-13beta-Hydroxystylopine 6452886 Click to see C1CN2CC3=C(C=CC4=C3OCO4)C(C2C5=CC6=C(C=C51)OCO6)O 339.30 unknown https://doi.org/10.1007/S10600-007-0072-7
(+-)Thalictrifoline 335206 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC5=C4OCO5)OC)OC 353.40 unknown https://doi.org/10.1007/S10600-007-0072-7
(+/-)-Isocorypalmine 10220 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)O)C=C1)OC 341.40 unknown https://doi.org/10.1007/S10600-007-0072-7
(12S,13R)-17-methoxy-12-methyl-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-16-ol 101663202 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC5=C4OCO5)OC)O 339.40 unknown https://doi.org/10.1007/S10600-007-0072-7
(13aR)-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9,10-triol 163189285 Click to see COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)O)O 313.30 unknown https://doi.org/10.1007/S10600-007-0072-7
(S)-Scoulerine 439654 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)O)C=C1)O 327.40 unknown https://doi.org/10.1007/S10600-007-0072-7
(S)-Tetrahydrocolumbamine 440229 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)O)C=C1)OC 341.40 unknown https://doi.org/10.1007/S10600-007-0072-7
12H-Benzo[a]-1,3-benzodioxolo[4,5-g]quinolizin-9-ol, 6,6a,11,14-tetrahydro-8-methoxy- 590762 Click to see COC1=C(C=C2CCN3CC4=C(CC3C2=C1)C=CC5=C4OCO5)O 325.40 unknown https://doi.org/10.1007/S10600-007-0072-7
16,17-Dimethoxy-12-methyl-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaene 3651568 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC5=C4OCO5)OC)OC 353.40 unknown https://doi.org/10.1055/S-2007-981549
https://doi.org/10.1007/S10600-007-0072-7
17-Methoxy-12-methyl-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-16-ol 74420699 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC5=C4OCO5)OC)O 339.40 unknown https://doi.org/10.1007/S10600-007-0072-7
2,3,10-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-9-ol 453215 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)O 341.40 unknown https://doi.org/10.1007/S10600-007-0072-7
3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9,10-triol 144020841 Click to see COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)O)O 313.30 unknown https://doi.org/10.1007/S10600-007-0072-7
5,7,17,19-Tetraoxa-13-azahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-2,4(8),9,15(23),16(20),21-hexaen-24-ol 78410986 Click to see C1CN2CC3=C(C=CC4=C3OCO4)C(C2C5=CC6=C(C=C51)OCO6)O 339.30 unknown https://doi.org/10.1007/S10600-007-0072-7
Cavidine 193148 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC5=C4OCO5)OC)OC 353.40 unknown https://doi.org/10.1055/S-2007-981549
https://doi.org/10.1007/S10600-007-0072-7
Cheilanthifoline 101277425 Click to see COC1=C(C=C2CCN3CC4=C(CC3C2=C1)C=CC5=C4OCO5)O 325.40 unknown https://doi.org/10.1007/S10600-007-0072-7
Corydalin 326549 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC 369.50 unknown https://doi.org/10.1055/S-2007-981549
Corydaline 101301 Click to see CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC 369.50 unknown https://doi.org/10.1055/S-2007-981549
D-Tetrahydropalmatine 969488 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC 355.40 unknown https://doi.org/10.1055/S-2007-981549
DL-Tetrahydropalmatine 5417 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC 355.40 unknown https://doi.org/10.1055/S-2007-981549
https://doi.org/10.1007/S10600-007-0072-7
L-sinactine 8016594 Click to see COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C5=C(C=C4)OCO5)OC 339.40 unknown https://doi.org/10.1007/S10600-007-0072-7
Scoulerine 22955 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)O)C=C1)O 327.40 unknown https://doi.org/10.1007/S10600-007-0072-7
Sinactine 5321317 Click to see COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C5=C(C=C4)OCO5)OC 339.40 unknown https://doi.org/10.1007/S10600-007-0072-7
Stylopin 697545 Click to see C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6 323.30 unknown https://doi.org/10.1055/S-2007-981549
Stylopine 440583 Click to see C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6 323.30 unknown https://doi.org/10.1007/S10600-007-0072-7
Tetrahydrocoptisine 6770 Click to see C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6 323.30 unknown https://doi.org/10.1007/S10600-007-0072-7
https://doi.org/10.1055/S-2007-981549
Tetrahydropalmatine 72301 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC 355.40 unknown https://doi.org/10.1007/S10600-007-0072-7
Tetrahydropalmatrubine 11282465 Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)O 341.40 unknown https://doi.org/10.1007/S10600-007-0072-7
> Alkaloids and derivatives / Protopine alkaloids
Protopine 4970 Click to see CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3 353.40 unknown https://doi.org/10.1055/S-2007-981549

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