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Stephania epigaea

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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
Contributors
Collections

Details Top

Internal ID UUID6440551baf591124922505
Scientific name Stephania epigaea
Authority H.S.Lo
First published in Acta Phytotax. Sin. 16(1): 34 (1978)

Description Top

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Synonyms Top

No known synonyms.

Common names Top

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Language Common/alternative name
Chinese 地不容
Chinese 雅丽千金藤
Chinese 地不容(山乌龟）

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001238639
Tropicos 50098929
KEW urn:lsid:ipni.org:names:581420-1
The Plant List tro-50098929
Open Tree Of Life 5503522
NCBI Taxonomy 1501461
IPNI 581420-1
GBIF 5592890
CMAUP NPO25189

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnobotanical study of medicinal plants used by the Yi people in Mile, Yunnan, China Li H, Huang C, Li Y, Wang P, Sun J, Bi Z, Xia S, Xiong Y, Bai X, Huang X J Ethnobiol Ethnomed 23-Feb-2024
PMCID:PMC10893717
doi:10.1186/s13002-024-00656-1
PMID:38395900
Ethnobotanical study on medicinal plants used by Bulang people in Yunnan, China Zhou H, Zhang J, Kirbis BS, Mula Z, Zhang W, Kuang Y, Huang Q, Yin L J Ethnobiol Ethnomed 07-Sep-2023
PMCID:PMC10486041
doi:10.1186/s13002-023-00609-0
PMID:37679773
Alkaloid variations within the genus Stephania (Menispermaceae) in China Qi B, Li L, Huang R Heliyon 16-May-2023
PMCID:PMC10256896
doi:10.1016/j.heliyon.2023.e16344
PMID:37305452
Unraveling the mechanism of action of cepharanthine for the treatment of novel coronavirus pneumonia (COVID-19) from the perspectives of systematic pharmacology Sun F, Liu J, Tariq A, Wang Z, Wu Y, Li L Arab J Chem 06-Mar-2023
PMCID:PMC9987614
doi:10.1016/j.arabjc.2023.104722
PMID:36910427
Phylogenomics and phylogeography of Menispermum (Menispermaceae) Song S, Cameron KM, Wang Y, Wang S, Jin X, Hina F, Yang Z, Li P Front Plant Sci 22-Feb-2023
PMCID:PMC9992823
doi:10.3389/fpls.2023.1116300
PMID:36909420
Current status and future challenges in extraction, purification and identification of Cepharanthine (a potential drug against COVID-19) Wang Y, Zhou X, Wei S, Wang G, Xi J Sep Purif Technol 29-Dec-2022
PMCID:PMC9797411
doi:10.1016/j.seppur.2022.123038
PMID:36593875
Pharmacological Effects and Clinical Prospects of Cepharanthine Liang D, Li Q, Du L, Dou G Molecules 15-Dec-2022
PMCID:PMC9782661
doi:10.3390/molecules27248933
PMID:36558061
Effect of Cepharanthine on the Stemness of Lung Squamous Cell Carcinoma Based on Network Pharmacology and Bioinformatics Liu B, Deng JX Biomed Res Int 28-Nov-2022
PMCID:PMC9723418
doi:10.1155/2022/5956526
PMID:36483630
The complete chloroplast genome sequence of the medicinal plant Stephania epigaea H. S. Lo, 1978 (Menispermaceae) from Yunnan, China Guan Q, Feng D, Fan M Mitochondrial DNA B Resour 29-Jul-2022
PMCID:PMC9341361
doi:10.1080/23802359.2022.2104670
PMID:35923633
Cepharanthine: A Promising Old Drug against SARS‐CoV‐2 Fan H, He S, Han P, Hong B, Liu K, Li M, Wang S, Tong Y Adv Biol (Weinh) 01-Jul-2022
PMCID:PMC9350037
doi:10.1002/adbi.202200148
PMID:35775953
Market survey on the traditional medicine of the Lijiang area in Yunnan Province, China Zhang M, Li H, Wang J, Tang M, Zhang X, Yang S, Liu J, Li Y, Huang X, Li Z, Huang L J Ethnobiol Ethnomed 23-May-2022
PMCID:PMC9125852
doi:10.1186/s13002-022-00532-w
PMID:35606860
Identification of Bioactive Components of Stephania epigaea Lo and Their Potential Therapeutic Targets by UPLC-MS/MS and Network Pharmacology Li X, Li M, Mao Z, Du Y, Brown S, Min X, Zhang R, Zhong Y, Dong Y, Liu Z, Lin C Evid Based Complement Alternat Med 27-Apr-2022
PMCID:PMC9068296
doi:10.1155/2022/3641586
PMID:35529936
A Comprehensive Review on the Chemical Properties, Plant Sources, Pharmacological Activities, Pharmacokinetic and Toxicological Characteristics of Tetrahydropalmatine Du Q, Meng X, Wang S Front Pharmacol 26-Apr-2022
PMCID:PMC9086320
doi:10.3389/fphar.2022.890078
PMID:35559252
Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look Heinrich M, Mah J, Amirkia V Molecules 25-Mar-2021
PMCID:PMC8036335
doi:10.3390/molecules26071836
PMID:33805869
Potential of Naturally Derived Alkaloids as Multi-Targeted Therapeutic Agents for Neurodegenerative Diseases Kong YR, Tay KC, Su YX, Wong CK, Tan WN, Khaw KY Molecules 30-Jan-2021
PMCID:PMC7866829
doi:10.3390/molecules26030728
PMID:33573300

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Hasubanan alkaloids
(1S,13S)-14,15-dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[11.4.3.01,13.02,10.04,8]icosa-2,4(8),9,14-tetraen-16-one 44584410 Click to see CN1CCC23C1(CCC4=CC5=C(C=C42)OCO5)C(=C(C(=O)C3)OC)OC 357.40 unknown https://doi.org/10.1021/NP9702042
Hasubanan-7-one,6-didehyydro-4,6-dimethoxy-17-methyl-2,3-[methylene bis(oxy)]- 360850 Click to see CN1CCC23C1(CCC4=CC5=C(C=C42)OCO5)C(=C(C(=O)C3)OC)OC 357.40 unknown https://doi.org/10.1021/NP9702042
> Lignans, neolignans and related compounds
(+)-2'-Norcepharanthine 181384 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7)OC)O4)OC)OCO3 592.70 unknown via CMAUP database
(13R,14S)-22,33-dimethoxy-13-methyl-13-oxido-2,5,7,20-tetraoxa-28-aza-13-azoniaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),27,31,34-tridecaene 71714024 Click to see C[N+]1(CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7=NCCC8=CC(=C(O4)C=C87)OC)OC)OCO3)[O-] 606.70 unknown via CMAUP database
Cepharanthine 10206 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3 606.70 unknown via CMAUP database
Fangchinoline 73481 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC 608.70 unknown via CMAUP database
Homoaromoline 99620 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=CC(=C(C=C7CCN6C)OC)O3)OC)O)OC 608.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Palmitic Acid 985 Click to see CCCCCCCCCCCCCCCC(=O)O 256.42 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(3S,4R,4aR,6aR,6bS,8R,8aS,12aS,14aR,14bR)-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-3,8-diol 21594139 Click to see CC1(CCC2(C(C1)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)O)C)CO)C 474.70 unknown via CMAUP database
clethroidoside F 56601861 Click to see CC(=O)OC1C(C23COC4(C2CC1(C)C)CCC5C6(CCC(C(C6CCC5(C4(CC3O)C)C)(C)C)OC7C(C(C(CO7)OC8C(C(C(C(O8)CO)O)O)OC9C(C(C(CO9)O)O)O)O)OC1C(C(C(C(O1)CO)O)O)O)C)OC(=O)C 1163.30 unknown via CMAUP database
desglucoanagalloside B 21681168 Click to see CC1(CCC23COC4(C2C1)CCC5C6(CCC(C(C6CCC5(C4(CC3O)C)C)(C)CO)OC7C(C(C(CO7)OC8C(C(C(C(O8)CO)O)O)OC9C(C(C(CO9)O)O)O)O)OC1C(C(C(C(O1)CO)O)O)O)C)C 1063.20 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
Stigmasterol 5280794 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 412.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Isorhamnetin 5281654 Click to see COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 316.26 unknown via CMAUP database
Kaempferol 5280863 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 286.24 unknown via CMAUP database
Quercetin 5280343 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O 302.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Cacticin 5318644 Click to see COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 478.40 unknown via CMAUP database
Hyperoside 5281643 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O 464.40 unknown via CMAUP database

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