Daphne acutiloba - Unknown
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Internal ID UUID644015b4cb857169929593
Scientific name Daphne acutiloba
Authority Rehder
First published in Pl. Wilson. 2: 539 (1916)

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Synonyms Top

Scientific name Authority First published in
Daphne odora subsp. acutiloba (Rehder) Halda Acta Mus. Richnov., Sect. Nat. 5: 165 (1998)

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Language Common/alternative name
Arabic دفنة حادة الفلقات
Chinese 滇瑞香
Chinese 尖瓣瑞香

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000637436
Tropicos 50177144
KEW urn:lsid:ipni.org:names:831130-1
The Plant List kew-2756807
Open Tree Of Life 6119220
NCBI Taxonomy 2753872
IPNI 831130-1
GBIF 5524464
EPPO DAPAC
EOL 2889990
USDA GRIN 13251
Wikipedia Daphne_acutiloba

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Inhibition of NO Production in LPS-Stimulated Primary Rat Glial Cells by Gnidilatimonoein and Extract of Daphne mucronata Bahrami Salehloo E, Sabouni F, Mianabadi M Iran J Biotechnol 01-Apr-2023
PMCID:PMC10203186
doi:10.30498/ijb.2023.285965.3052
PMID:37228631
Phytochemistry and Pharmacological Activities of the Diterpenoids from the Genus Daphne Nie YW, Li Y, Luo L, Zhang CY, Fan W, Gu WY, Shi KR, Zhai XX, Zhu JY Molecules 31-Oct-2021
PMCID:PMC8588408
doi:10.3390/molecules26216598
PMID:34771007
Potential of diterpene compounds as antivirals, a review Wardana AP, Aminah NS, Rosyda M, Abdjan MI, Kristanti AN, Tun KN, Choudhary MI, Takaya Y Heliyon 12-Aug-2021
PMCID:PMC8359577
doi:10.1016/j.heliyon.2021.e07777
PMID:34405122
Plant-derived lignans as potential antiviral agents: a systematic review Xu XY, Wang DY, Li YP, Deyrup ST, Zhang HJ Phytochem Rev 31-May-2021
PMCID:PMC8165688
doi:10.1007/s11101-021-09758-0
PMID:34093097
New Antiproliferative Triflavanone from Thymelaea hirsuta—Isolation, Structure Elucidation and Molecular Docking Studies Elhady SS, Abdelhameed RF, El-Ayouty MM, Ibrahim AK, Habib ES, Elgawish MS, Hassanean HA, Safo MK, Nafie MS, Ahmed SA Molecules 31-Jan-2021
PMCID:PMC7867015
doi:10.3390/molecules26030739
PMID:33572651
Structure-Activity-Relationship and Mechanistic Insights for Anti-HIV Natural Products Kaur R, Sharma P, Gupta GK, Ntie-Kang F, Kumar D Molecules 29-Apr-2020
PMCID:PMC7249135
doi:10.3390/molecules25092070
PMID:32365518
Yuccalechins A–C from the Yucca schidigera Roezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities Pecio Ł, Alilou M, Kozachok S, Erdogan Orhan I, Eren G, Senol Deniz FS, Stuppner H, Oleszek W Molecules 16-Nov-2019
PMCID:PMC6891570
doi:10.3390/molecules24224162
PMID:31744162
Monitoring the Chemical Profile in Agarwood Formation within One Year and Speculating on the Biosynthesis of 2-(2-Phenylethyl)Chromones Liao G, Dong WH, Yang JL, Li W, Wang J, Mei WL, Dai HF Molecules 25-May-2018
PMCID:PMC6100365
doi:10.3390/molecules23061261
PMID:29799457
Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus Salehi B, Kumar NV, Şener B, Sharifi-Rad M, Kılıç M, Mahady GB, Vlaisavljevic S, Iriti M, Kobarfard F, Setzer WN, Ayatollahi SA, Ata A, Sharifi-Rad J Int J Mol Sci 14-May-2018
PMCID:PMC5983620
doi:10.3390/ijms19051459
PMID:29757986
Two New Daucane Sesquiterpenoids from Daphne aurantiaca Zhao YX, Huang SZ, Ma QY, Mei WL, Dai HF Molecules 24-Aug-2012
PMCID:PMC6268740
doi:10.3390/molecules170910046
PMID:22922275
Daphnane-type diterpene esters with cytotoxic and anti-HIV-1 activities from Daphne acutiloba Rehd. Huang SZ, Zhang XJ, Li XY, Kong LM, Jiang HZ, Ma QY, Liu YQ, Hu JM, Zheng YT, Li Y, Zhou J, Zhao YX Phytochemistry 01-Mar-2012
doi:10.1016/J.PHYTOCHEM.2011.11.013
PMID:22196934
Two biflavonoids from Daphne acutiloba Masahiko Taniguchi, Akiko Fujiwara, Kimiye Baba, Nian-He Wang Elsevier BV 26-Jul-2002
doi:10.1016/S0031-9422(98)00181-2

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Coumarinolignans
Daphneticin 158341 Click to see COC1=CC(=CC(=C1O)OC)C2C(OC3=C(O2)C=CC4=C3OC(=O)C=C4)CO 386.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Lignans, neolignans and related compounds / Furanoid lignans
4-[(3aS,6aR)-6-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol 137705081 Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O 358.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Pinoresinol 73399 Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O 358.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
(+)-Nortrachelogenin 479756 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)O)OC)O)O 374.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
3-Hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 321311 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)O)OC)O)O 374.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Lignans, neolignans and related compounds / Lignan glycosides
(2S,3R,4S,5S,6R)-2-[4-[(3S,3aR,6S,6aR)-3-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 486614 Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC)O 520.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Symplocosin 5351523 Click to see COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC)O 520.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Rhamnofolane and daphnane diterpenoids
(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7,17-trihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-[(1E,3E,5E)-nona-1,3,5-trienyl]-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-5-one 163054006 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)O)C)C=C(C6=O)C)O)O)CO 542.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7,17-trihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-5-one 162931401 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)O 498.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-16-isopropenyl-4,18-dimethyl-14-[(1E,3E,5E)-nona-1,3,5-trienyl]-5-oxo-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] benzoate 162650645 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)OC(=O)C7=CC=CC=C7)C)C=C(C6=O)C)O)O)CO 646.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-16-isopropenyl-4,18-dimethyl-5-oxo-14-phenyl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] (2E,4E,6E)-deca-2,4,6-trienoate 101281330 Click to see CCCC=CC=CC=CC(=O)OC1C(C23C4C=C(C(=O)C4(C(C5(C(C2C6C1(OC(O6)(O3)C7=CC=CC=C7)C(=C)C)O5)CO)O)O)C)C 646.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-[(1E,3E,5E)-nona-1,3,5-trienyl]-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] acetate 162890097 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)OC(=O)C)C)C=C(C6=O)C)O)O)CO 584.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] (2E,4E)-deca-2,4-dienoate 101281331 Click to see CCCCCC=CC=CC(=O)OC1C(C23C4C=C(C(=O)C4(C(C5(C(C2C6C1(OC(O6)(O3)C7=CC=CC=C7)C(=C)C)O5)CO)O)O)C)C 648.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-nona-1,3,5-trienyl-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] acetate 75069612 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)OC(=O)C)C)C=C(C6=O)C)O)O)CO 584.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-nona-1,3,5-trienyl-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] benzoate 162861794 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)OC(=O)C7=CC=CC=C7)C)C=C(C6=O)C)O)O)CO 646.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] 3-phenylprop-2-enoate 5462 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)OC(=O)C=CC8=CC=CC=C8 628.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] deca-2,4-dienoate 428493 Click to see CCCCCC=CC=CC(=O)OC1C(C23C4C=C(C(=O)C4(C(C5(C(C2C6C1(OC(O6)(O3)C7=CC=CC=C7)C(=C)C)O5)CO)O)O)C)C 648.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] deca-2,4,6-trienoate 99839 Click to see CCCC=CC=CC=CC(=O)OC1C(C23C4C=C(C(=O)C4(C(C5(C(C2C6C1(OC(O6)(O3)C7=CC=CC=C7)C(=C)C)O5)CO)O)O)C)C 646.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
12-Benzoyldaphnetoxin 428494 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)OC(=O)C8=CC=CC=C8 602.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
6,7,17-Trihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-nona-1,3,5-trienyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-5-one 75069611 Click to see CCCC=CC=CC=CC12OC3C4C5C(O5)(C(C6(C(C4(O1)C(C(C3(O2)C(=C)C)O)C)C=C(C6=O)C)O)O)CO 542.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
Daphnetoxin,12-hydroxy 99841 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)O 498.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
Genkwadaphnin 73351913 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)OC(=O)C8=CC=CC=C8 602.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
Gnidicin 70691946 Click to see CC1C(C2(C3C4C1(C5C=C(C(=O)C5(C(C6(C4O6)CO)O)O)C)OC(O3)(O2)C7=CC=CC=C7)C(=C)C)OC(=O)C=CC8=CC=CC=C8 628.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2011.11.013
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
2-(Hydroxymethyl)-6-[4-(3-hydroxyprop-1-enyl)-2,6-dimethoxyphenoxy]oxane-3,4,5-triol 323959 Click to see COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)C=CCO 372.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Eleutheroside B 5316860 Click to see COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)C=CCO 372.40 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Chromones
(1S,4R,12S,13R)-13,16,18-trihydroxy-4,12-bis(4-hydroxyphenyl)-3,11,21-trioxapentacyclo[11.8.0.01,10.02,7.015,20]henicosa-2(7),9,15,17,19-pentaene-8,14-dione 15378975 Click to see C1CC2=C(C34C(=CC2=O)OC(C3(C(=O)C5=C(C=C(C=C5O4)O)O)O)C6=CC=C(C=C6)O)OC1C7=CC=C(C=C7)O 542.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
(1S,4S,12S,13R)-13,16,18-trihydroxy-4,12-bis(4-hydroxyphenyl)-3,11,21-trioxapentacyclo[11.8.0.01,10.02,7.015,20]henicosa-2(7),9,15,17,19-pentaene-8,14-dione 15378974 Click to see C1CC2=C(C34C(=CC2=O)OC(C3(C(=O)C5=C(C=C(C=C5O4)O)O)O)C6=CC=C(C=C6)O)OC1C7=CC=C(C=C7)O 542.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
[(2R,3S,8S,9R)-3,5-dihydroxy-2,8-bis(4-hydroxyphenyl)-3,4,8,9-tetrahydro-2H-furo[2,3-h]chromen-9-yl]-(3,4,5-trihydroxyphenyl)methanone 101701124 Click to see C1C(C(OC2=C1C(=CC3=C2C(C(O3)C4=CC=C(C=C4)O)C(=O)C5=CC(=C(C(=C5)O)O)O)O)C6=CC=C(C=C6)O)O 544.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Daphnodorin A 72426 Click to see C1CC2=C(C3=C(C=C2O)OC(=C3C(=O)C4=C(C=C(C=C4O)O)O)C5=CC=C(C=C5)O)OC1C6=CC=C(C=C6)O 526.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / Coumarins and derivatives / Coumarin glycosides
Daphnin 439499 Click to see C1=CC(=C(C2=C1C=CC(=O)O2)O)OC3C(C(C(C(O3)CO)O)O)O 340.28 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Daphnin (daphnetin-7-O-glucoside) 626442 Click to see C1=CC(=C(C2=C1C=CC(=O)O2)O)OC3C(C(C(C(O3)CO)O)O)O 340.28 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7,8-dihydroxycoumarins
Daphnetin 5280569 Click to see C1=CC(=C(C2=C1C=CC(=O)O2)O)O 178.14 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Daphnoretin 5281406 Click to see COC1=C(C=C2C(=C1)C=C(C(=O)O2)OC3=CC4=C(C=C3)C=CC(=O)O4)O 352.30 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
Umbelliferone 5281426 Click to see C1=CC(=CC2=C1C=CC(=O)O2)O 162.14 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
Daphnodorin F 70688394 Click to see C1CC2=C(C3=C(C=C2O)OC4(C3(C(=O)C5=C(C=C(C=C5O4)O)O)O)C6=CC=C(C=C6)O)OC1C7=CC=C(C=C7)O 542.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2
> Phenylpropanoids and polyketides / Isoflavonoids / Pyranoisoflavonoids
3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-6-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one 101701125 Click to see C1CC2=C(C=C(C(=C2O)C3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)O)OC1C6=CC=C(C=C6)O 526.50 unknown https://doi.org/10.1016/S0031-9422(98)00181-2

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