Calophyllum teysmannii
Details Top
| Internal ID | UUID64400ef29096d606163704 |
| Scientific name | Calophyllum teysmannii |
| Authority | Miq. |
| First published in | Fl. Ned. Ind., Eerste Bijv. : 499 (1861) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Among the Visayan and Tagalog communities of the Philippines, the leaves of Calophyllum teysmannii are brewed as a warm tea to soothe cough and throat irritation (Bennett et al., 2021). In the same region, the bark is boiled in water for about thirty minutes to produce a decoction that is taken to treat dysentery and abdominal pain (Bennett et al., 2021). In the Malay Peninsula, the Dayak people of Borneo crush fresh leaves into a poultice that is applied directly to cuts and skin infections (PROSEA, 1995). In central Vietnam, the Kinh and other ethnic groups steep the dried leaves in hot water for a short infusion to lower fever and alleviate malaria symptoms (Nguyen et al., 2015). Across these cultures, both the leaf infusion and the bark decoction are the primary preparations, and all involve the direct consumption or topical application of aqueous extracts.
The simplest preparation is a mild leaf tea. Place 10 g of dried leaves in 500 ml of water, bring to a gentle boil, then simmer for 10 minutes. After turning off the heat, allow the mixture to steep for an additional 5 minutes, strain, and drink one cup 2–3 times a day. Do not exceed three cups per day, and avoid use during pregnancy because the plant contains coumarins that may have uterine‑stimulating effects (Bennett et al., 2021).
Phytochemical work on Calophyllum teysmannii has identified several bioactive classes. The bark and leaves contain xanthones such as caloxanthone and the pair of teysmannins A and B (Tanaka et al., 2007), as well as coumarins like calophyllic acid (Li et al., 2008). The triterpenoid friedelin has also been isolated from the bark (Li et al., 2008). These compounds have documented anti‑inflammatory, antimicrobial and astringent properties, which align with the traditional uses of the leaf tea for respiratory relief and the bark decoction for gastrointestinal complaints. In cell‑culture assays, the xanthones suppress nitric‑oxide production by macrophages, supporting their role in reducing respiratory inflammation, and the coumarins have shown mild anticoagulant activity in platelet‑aggregation tests, which explains the caution advised for patients on blood‑thinners.
Recent in‑vitro studies have shown that the isolated xanthones suppress pro‑inflammatory mediators, prompting interest in developing standardized extracts for pharmaceutical use, while dried leaves and bark continue to be sold in local markets in the Philippines and Indonesia for their traditional therapeutic value. In the Philippines, a handful of herbal companies market dried Calophyllum teysmannii leaves and bark as “teyso” or “taysaman” teas and tinctures, and ongoing research in the region is focusing on standardizing the xanthone content for potential anti‑inflammatory nutraceuticals (Molnár, 2010).
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Calophyllum inophylloide var. singapurense | M.R.Hend. & Wyatt-Sm. | Gard. Bull. Singapore 15: 316. 1956 [20 Nov 1956] |
| Calophyllum intramarginale | M.R.Hend. & Wyatt-Sm. | Gard. Bull. Singapore 15: 342 (1956) |
| Calophyllum miquelii | Vesque | Monogr. Phan. [A.DC. & C.DC.] 8: 607. 1893 [Dec 1893] |
Varieties (abbr. var.) Top
Add a new one! Suggest a correction!| Name | Authority | First published in |
|---|---|---|
| Calophyllum teysmannii var. bursiculum | P.F.Stevens | J. Arnold Arbor. 61: 436 (1980) |
| Calophyllum teysmannii var. inophylloide | (King) P.F.Stevens | J. Arnold Arbor. 61: 436 (1980) |
| Calophyllum teysmannii var. teysmannii | Unknown |
Germination/Propagation Top
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No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-tropical click to expand
-
Indo-China
- Cambodia
- Thailand
-
Malesia
- Borneo
- Malaya
- Sumatera
-
Indo-China
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000581366 |
| Tropicos | 100303882 |
| KEW | urn:lsid:ipni.org:names:427317-1 |
| The Plant List | kew-2693516 |
| Open Tree Of Life | 415307 |
| NCBI Taxonomy | 667334 |
| IPNI | 427317-1 |
| iNaturalist | 428102 |
| GBIF | 6032514 |
| EOL | 5710295 |
| USDA GRIN | 411477 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / O-methoxybenzoic acids and derivatives | |||||
| 3,6-Dihydroxy-2-methoxybenzoic acid | 15647609 | Click to see | 184.15 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids | |||||
| (-)-Ledol | 6431133 | Click to see | 222.37 | unknown | https://doi.org/10.1080/10575630008043783 |
| (1aS,4S,7bR)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol | 25089154 | Click to see | 222.37 | unknown | https://doi.org/10.1080/10575630008043783 |
| > Lipids and lipid-like molecules / Prenol lipids / Triterpenoids | |||||
| (4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol | 137795506 | Click to see | 428.70 | unknown | https://doi.org/10.1080/10575630008043783 |
| Betulinic Acid | 64971 | Click to see | 456.70 | unknown | https://doi.org/10.3987/COM-97-7901 |
| Friedelin | 91472 | Click to see | 426.70 | unknown | https://doi.org/10.1080/10575630008043783 |
| Friedelinol | 101341 | Click to see CC1C(CCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C)C)C)C)C)C)O | 428.70 | unknown | https://doi.org/10.1080/10575630008043783 |
| Lup-20(29)-en-28-oic acid, 3beta-hydroxy- | 2371 | Click to see | 456.70 | unknown | https://doi.org/10.3987/COM-97-7901 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| Stigmasterol | 5280794 | Click to see | 412.70 | unknown | https://doi.org/10.1080/10575630008043783 |
| > Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones | |||||
| (2R)-4-(4-methoxy-9-oxoxanthen-3-yl)-2-methylbutanoic acid | 162879668 | Click to see | 326.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| (2R)-4-(8-hydroxy-4-methoxy-9-oxoxanthen-3-yl)-2-methylbutanoic acid | 162893765 | Click to see | 342.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| (2S)-4-(4-methoxy-9-oxoxanthen-3-yl)-2-methylbutanoic acid | 162879667 | Click to see | 326.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,2,8-Trimethoxyxanthone | 85931281 | Click to see | 286.28 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,3-Dihydroxy-4,6,8-trimethoxyxanthen-9-one | 101035766 | Click to see | 318.28 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,3-Dimethoxy-5,8-dihydroxyxanthone | 53348043 | Click to see COC1=CC2=C(C(=C1)OC)C(=O)C3=C(C=CC(=C3O2)O)O | 288.25 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,5-Dihydroxy-6-(4-hydroxy-3-methylbutyl)xanthen-9-one | 85768635 | Click to see CC(CCC1=C(C2=C(C=C1)C(=O)C3=C(C=CC=C3O2)O)O)CO | 314.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,5-dihydroxy-6-[(3S)-4-hydroxy-3-methylbutyl]xanthen-9-one | 162939757 | Click to see | 314.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 1,8-Dimethoxy-2-hydroxyxanthone | 493307 | Click to see | 272.25 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 2-Hydroxy-1-methoxyxanthone | 10399460 | Click to see COC1=C(C=CC2=C1C(=O)C3=CC=CC=C3O2)O | 242.23 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 2-Hydroxy-1,7,8-trimethoxyxanthen-9-one | 101717282 | Click to see | 302.28 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| 2-Hydroxyxanthone | 74708 | Click to see | 212.20 | unknown |
https://doi.org/10.1016/S0031-9422(00)00289-2 https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 2,8-Dihydroxy-1-methoxyxanthone | 5464640 | Click to see | 258.23 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 3,8-Dihydroxy-1,2-dimethoxy-9H-xanthen-9-one | 14630572 | Click to see | 288.25 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 4-(4-Methoxy-9-oxoxanthen-3-yl)-2-methylbutanoic acid | 56612721 | Click to see CC(CCC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3O2)OC)C(=O)O | 326.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 4-(8-Hydroxy-4-methoxy-9-oxoxanthen-3-yl)-2-methylbutanoic acid | 12315435 | Click to see | 342.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 6-Hydroxy-1,2,5-trimethoxyxanthen-9-one | 101717280 | Click to see COC1=C(C2=C(C=C1)OC3=C(C2=O)C=CC(=C3OC)O)OC | 302.28 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| 6-Hydroxy-1,3,5,7-tetramethoxyxanthen-9-one | 102460794 | Click to see COC1=CC2=C(C(=C1)OC)C(=O)C3=CC(=C(C(=C3O2)OC)O)OC | 332.30 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 6-Methoxy-9-oxo-9H-xanthene-2-carboxylic acid methyl ester | 637117 | Click to see COC1=CC2=C(C=C1)C(=O)C3=C(O2)C=CC(=C3)C(=O)OC | 284.26 | unknown |
https://doi.org/10.1016/S0031-9422(00)00289-2 https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 8-Hydroxy-1,2-dimethoxyxanthen-9-one | 85948687 | Click to see | 272.25 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| 9H-Xanthen-9-one, 3-hydroxy-2,4-dimethoxy- | 12214333 | Click to see COC1=C(C(=C2C(=C1)C(=O)C3=CC=CC=C3O2)OC)O | 272.25 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| 9H-Xanthen-9-one, 3,8-dihydroxy-1,2,4-trimethoxy- | 5491745 | Click to see | 318.28 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| Buchanaxanthone | 5481840 | Click to see | 258.23 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| Euxanthone | 5281631 | Click to see | 228.20 | unknown | https://doi.org/10.1016/S0031-9422(99)00520-8 |
| Gentisin | 5281636 | Click to see COC1=CC(=C2C(=C1)OC3=C(C2=O)C=C(C=C3)O)O | 258.23 | unknown |
https://doi.org/10.1016/S0031-9422(00)00289-2 https://doi.org/10.1016/S0031-9422(99)00520-8 |
| Methyl 7-methoxy-9-oxoxanthene-3-carboxylate | 162993705 | Click to see | 284.26 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| > Organoheterocyclic compounds / Benzopyrans / 2-benzopyrans | |||||
| (3R)-6-methoxy-3,7-dimethyl-3,4-dihydro-1H-isochromen-8-ol | 21775856 | Click to see | 208.25 | unknown | https://doi.org/10.1016/S0031-9422(00)00289-2 |
| > Phenylpropanoids and polyketides / Coumarins and derivatives / Pyranocoumarins / Angular pyranocoumarins | |||||
| Calanolide A | 64972 | Click to see CCCC1=CC(=O)OC2=C1C3=C(C=CC(O3)(C)C)C4=C2C(C(C(O4)C)C)O | 370.40 | unknown | https://doi.org/10.1016/S0960-894X(01)80543-6 |
| Calanolide F | 122843 | Click to see | 370.40 | unknown | https://doi.org/10.1021/NP980140A |
| Costatolide | 461128 | Click to see CCCC1=CC(=O)OC2=C1C3=C(C=CC(O3)(C)C)C4=C2C(C(C(O4)C)C)O | 370.40 | unknown | https://doi.org/10.1076/PHBI.37.1.71.6326 |
| > Phenylpropanoids and polyketides / Diarylheptanoids / Linear diarylheptanoids | |||||
| 4-Phenyl-5-methoxy-7-hydroxy-8-benzoylcoumarin | 10809277 | Click to see | 372.40 | unknown | https://doi.org/10.3987/COM-97-7901 |
| > Phenylpropanoids and polyketides / Neoflavonoids / Prenylated neoflavonoids | |||||
| (-)-Inophyllum P | 72978 | Click to see | 404.50 | unknown |
https://doi.org/10.1076/PHBI.37.1.71.6326 https://doi.org/10.1016/S0960-894X(01)80543-6 https://doi.org/10.1016/S0040-4039(00)78193-7 |
| (16R,17S)-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaene-4,18-dione | 455251 | Click to see | 402.40 | unknown |
https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1016/S0031-9422(98)80071-X |
| (16S,17S)-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaene-4,18-dione | 5352084 | Click to see | 402.40 | unknown |
https://doi.org/10.1016/S0031-9422(98)80071-X https://doi.org/10.1016/S0040-4039(00)78193-7 |
| (2R)-5-benzoyl-4-hydroxy-2-(2-hydroxypropan-2-yl)-9-phenyl-2,3-dihydrofuro[2,3-f]chromen-7-one | 163024126 | Click to see CC(C)(C1CC2=C(C(=C3C(=C2O1)C(=CC(=O)O3)C4=CC=CC=C4)C(=O)C5=CC=CC=C5)O)O | 442.50 | unknown | https://doi.org/10.3987/COM-97-7901 |
| (8R,9R)-5-methoxy-8,9-dimethyl-6-(3-methylbut-2-enyl)-4-phenyl-8,9-dihydropyrano[2,3-f]chromene-2,10-dione | 15381982 | Click to see | 418.50 | unknown |
https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1016/S0031-9422(98)80071-X |
| 12-O-Methylinophyllum A | 10645694 | Click to see CC1C(OC2=C(C1OC)C3=C(C(=CC(=O)O3)C4=CC=CC=C4)C5=C2C=CC(O5)(C)C)C | 418.50 | unknown | https://doi.org/10.3987/COM-97-7901 |
| 18-Methoxy-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaen-4-one | 85217621 | Click to see | 418.50 | unknown | https://doi.org/10.3987/COM-97-7901 |
| 5-Benzoyl-4-hydroxy-2-(2-hydroxypropan-2-yl)-9-phenyl-2,3-dihydrofuro[2,3-f]chromen-7-one | 11797452 | Click to see | 442.50 | unknown | https://doi.org/10.3987/COM-97-7901 |
| 5-Methoxy-8,9-dimethyl-6-(3-methylbut-2-enyl)-4-phenyl-8,9-dihydropyrano[2,3-f]chromene-2,10-dione | 162945629 | Click to see CC1C(OC2=C(C(=C3C(=CC(=O)OC3=C2C1=O)C4=CC=CC=C4)OC)CC=C(C)C)C | 418.50 | unknown |
https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1016/S0031-9422(98)80071-X |
| Calanone | 5352087 | Click to see | 424.40 | unknown |
https://doi.org/10.1016/S0040-4039(00)78193-7 https://doi.org/10.1080/10575639808044952 https://doi.org/10.1016/S0031-9422(98)80071-X https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1002/HLCA.19980810549 https://doi.org/10.3987/COM-97-7901 https://doi.org/10.1080/10575630008043783 |
| Inophyllolide chromanol | 15223670 | Click to see CC1C(OC2=C(C1O)C3=C(C(=CC(=O)O3)C4=CC=CC=C4)C5=C2C=CC(O5)(C)C)C | 404.50 | unknown | https://doi.org/10.1016/S0040-4039(00)78193-7 |
| Inophyllum C | 455252 | Click to see | 402.40 | unknown |
https://doi.org/10.1016/S0031-9422(98)80071-X https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1002/HLCA.19980810549 |
| Inophyllum E | 5254 | Click to see CC1C(OC2=C(C1=O)C3=C(C(=CC(=O)O3)C4=CC=CC=C4)C5=C2C=CC(O5)(C)C)C | 402.40 | unknown |
https://doi.org/10.1002/HLCA.19980810549 https://doi.org/10.1016/S0031-9422(97)00679-1 https://doi.org/10.1016/S0031-9422(98)80071-X https://doi.org/10.1016/S0040-4039(00)78193-7 |
| Isocalanone | 11004403 | Click to see | 424.40 | unknown |
https://doi.org/10.1002/HLCA.19980810549 https://doi.org/10.1080/10575630008043783 https://doi.org/10.1080/10575639808044952 |
| Teysmanone A | 15381981 | Click to see | 424.40 | unknown |
https://doi.org/10.1016/S0031-9422(98)80071-X https://doi.org/10.1016/S0031-9422(97)00679-1 |
Collections Top
| In private collections | 0 |
| In public collections | 0 |