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Internal ID UUID644022833578e974001986
Scientific name Smilax menispermoidea
Authority A.DC.
First published in Monogr. Phan. 1: 108 (1878)

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Synonyms Top

Scientific name Authority First published in
Smilax rubriflora Rehder J. Arnold Arbor. 9: 21 (1928)
Smilax luteocaulis H.Lév. Repert. Spec. Nov. Regni Veg. 13: 339 (1914)

Common names Top

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Language Common/alternative name
Vietnamese kim cang hoa nâu
Chinese 巒大菝葜
Chinese 红萆薢
Chinese 防己叶菝葜
Chinese 防己葉菝葜
Chinese 峦大菝葜

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • Tibet
  • Asia-tropical
    • Indian Subcontinent
      • East Himalaya
      • Nepal
      • West Himalaya
    • Indo-China
      • Laos
      • Myanmar
      • Vietnam

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000742709
Tropicos 18407397
KEW urn:lsid:ipni.org:names:541636-1
The Plant List kew-289301
Open Tree Of Life 73630
NCBI Taxonomy 1045158
IPNI 541636-1
iNaturalist 1231588
GBIF 5295209
EOL 1082801

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Diosgenin alleviates D-galactose-induced oxidative stress in rats’ brain and liver targeting aging and apoptotic marker genes El-Far AH, Elghaity MM, Mohamed SA, Noreldin AE, Elewa YH, Al Jaouni SK, Alsenosy AA Front Mol Biosci 23-Feb-2024
PMCID:PMC10922004
doi:10.3389/fmolb.2024.1303379
PMID:38463710
Market survey on the traditional medicine of the Lijiang area in Yunnan Province, China Zhang M, Li H, Wang J, Tang M, Zhang X, Yang S, Liu J, Li Y, Huang X, Li Z, Huang L J Ethnobiol Ethnomed 23-May-2022
PMCID:PMC9125852
doi:10.1186/s13002-022-00532-w
PMID:35606860
Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model Zhang C, Qin L, Sun B, Wu Y, Zhong F, Wu L, Liu T Sci Rep 18-Mar-2021
PMCID:PMC7973441
doi:10.1038/s41598-021-85822-1
PMID:33737640
Simultaneous Spectrophotometric Determination of Trigonelline, Diosgenin and Nicotinic Acid in Dosage Forms Prepared from Fenugreek Seed Extract Mohamadi N, Pournamdari M, Sharififar F, Ansari M Iran J Pharm Res 01-Mar-2020
PMCID:PMC7667557
doi:10.22037/ijpr.2019.1100790
PMID:33224220
Recent Advances in the Pharmacological Activities of Dioscin Yang L, Ren S, Xu F, Ma Z, Liu X, Wang L Biomed Res Int 14-Aug-2019
PMCID:PMC6710808
doi:10.1155/2019/5763602
PMID:31511824
Diosgenin-loaded niosome as an effective phytochemical nanocarrier: physicochemical characterization, loading efficiency, and cytotoxicity assay Hajizadeh MR, Parvaz N, Barani M, Khoshdel A, Fahmidehkar MA, Mahmoodi M, Torkzadeh-Mahani M Daru 27-May-2019
PMCID:PMC6592984
doi:10.1007/s40199-019-00277-0
PMID:31134490
Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review Sethi G, Shanmugam MK, Warrier S, Merarchi M, Arfuso F, Kumar AP, Bishayee A Nutrients 19-May-2018
PMCID:PMC5986524
doi:10.3390/nu10050645
PMID:29783752
An update on the biological and pharmacological activities of diosgenin Kim JK, Park SU EXCLI J 02-Jan-2018
PMCID:PMC5780621
doi:10.17179/excli2017-894
PMID:29383016
Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia Huang L, Li H, Xie D, Shi T, Wen C Oncotarget 09-Apr-2017
PMCID:PMC5522171
doi:10.18632/oncotarget.16983
PMID:28454110
Steroidal saponins from Smilax menispermoidea and S. lebrunii. Ju Y, Jia Z, Sun X Phytochemistry 01-Nov-1994
doi:10.1016/S0031-9422(00)90427-8
PMID:7765762
Steroidal saponins from Smilax lebrunii. Jia ZH, Ju Y Phytochemistry 01-Sep-1992
doi:10.1016/0031-9422(92)83469-F
PMID:1368413
Steroidal saponins from the rhizomes of Smilax menispermoidea. Ju Y, Jia ZJ Phytochemistry 01-Apr-1992
doi:10.1016/0031-9422(92)80288-P
PMID:1368051

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides
1-[3-[4-hydroxy-6-(hydroxymethyl)-3,5-bis[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl]oxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone 14776068 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC=C7C(=O)C)C)C)CO)O)O)O 768.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
Dracaenoside C 21582652 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC=C7C(=O)C)C)C)CO)O)O)O 768.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins
(25R)-3beta-(4-O-alpha-L-Rhamnopyranosyl-beta-D-glucopyranosyloxy)spirosta-5-ene 163035150 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)C)C)C)OC1 722.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
(2R,3R,4S,5R,6R)-2-[(1R,2S,4S,5'S,6R,7S,8S,9S,12S,13R,16S)-8-hydroxy-5'-(hydroxymethyl)-7,9,13-trimethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 101677503 Click to see CC1C2(CCC(CO2)CO)OC3C1(C4(CCC5C(C4C3)CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)O)O)C)C)O 608.80 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
(2S,3R,4R,5R,6S)-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-[(1R,2S,4S,5'S,6R,7S,8S,9S,12S,13R,16S)-8-hydroxy-5'-(hydroxymethyl)-7,9,13-trimethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 101677504 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3CCC4(C5CCC6(C(C5CC=C4C3)CC7C6(C(C8(O7)CCC(CO8)CO)C)O)C)C)CO)O)O)O 754.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
(2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-6-[(1R,2S,4S,5'S,6R,7S,8S,9S,12S,13R,16S)-8-hydroxy-5'-(hydroxymethyl)-7,9,13-trimethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-2-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol 163005460 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7(C(C9(O8)CCC(CO9)CO)C)O)C)C)CO)O)O)O 901.00 unknown https://doi.org/10.1016/0031-9422(92)83469-F
(2S,3R,4R,5R,6S)-2-[(2R,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-5-[(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(1S,2S,4S,8S,9S,12S,13R)-7,9,13-trimethyl-6-[(3S)-3-methyl-4-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,18-dien-16-yl]oxy]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 131801368 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7C(=C(O8)CCC(C)COC9C(C(C(C(O9)CO)O)O)O)C)C)C)CO)O)O)O 1031.20 unknown https://doi.org/10.1016/0031-9422(92)80288-P
(3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[[(1S,2S,4S,7S,8R,9S,12S,13R,16S)-6-methoxy-7,9,13-trimethyl-6-[(3S)-3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol 123134748 Click to see CC1C2C(CC3C2(CCC4C3CC=C5C4(CCC(C5)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)C)O)O)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)OC1(CCC(C)COC9C(C(C(C(O9)CO)O)O)O)OC 1063.20 unknown https://doi.org/10.1016/0031-9422(92)80288-P
2-[4-Hydroxy-2-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-6-[[7,9,13-trimethyl-6-[3-methyl-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,18-dien-16-yl]oxy]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 73817989 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7C(=C(O8)CCC(C)COC9C(C(C(C(O9)CO)O)O)O)C)C)C)CO)O)O)O 1031.20 unknown https://doi.org/10.1016/0031-9422(92)83469-F
2-[4-Hydroxy-2-(hydroxymethyl)-6-(5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl)oxy-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol 271916 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1 869.00 unknown https://doi.org/10.1016/0031-9422(92)83469-F
2-[4-Hydroxy-6-[8-hydroxy-5'-(hydroxymethyl)-7,9,13-trimethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-2-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol 163005459 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7(C(C9(O8)CCC(CO9)CO)C)O)C)C)CO)O)O)O 901.00 unknown https://doi.org/10.1016/0031-9422(92)83469-F
2-[4,5-Dihydroxy-6-[8-hydroxy-5'-(hydroxymethyl)-7,9,13-trimethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol 162969755 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3CCC4(C5CCC6(C(C5CC=C4C3)CC7C6(C(C8(O7)CCC(CO8)CO)C)O)C)C)CO)O)O)O 754.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
Dioscin 119245 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1 869.00 unknown https://doi.org/10.1016/0031-9422(92)80288-P
https://doi.org/10.1016/0031-9422(92)83469-F
Methylprotodioscin 11263254 Click to see CC1C2C(CC3C2(CCC4C3CC=C5C4(CCC(C5)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)C)O)O)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)OC1(CCC(C)COC9C(C(C(C(O9)CO)O)O)O)OC 1063.20 unknown https://doi.org/10.1016/0031-9422(92)83469-F
NSC-698790;Smilax saponin B 500376 Click to see CC1C2C(CC3C2(CCC4C3CC=C5C4(CCC(C5)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)C)O)O)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)OC1(CCC(C)COC9C(C(C(C(O9)CO)O)O)O)OC 1063.20 unknown https://doi.org/10.1016/0031-9422(92)83469-F
Ophiopogonin C' 4483248 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)C)OC1 722.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
Progenin II 44429638 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)C)C)C)OC1 722.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
Prosapogenin A 11061578 Click to see CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)C)OC1 722.90 unknown https://doi.org/10.1016/S0031-9422(00)90427-8
Pseudoprotodioscin 21637110 Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7C(=C(O8)CCC(C)COC9C(C(C(C(O9)CO)O)O)O)C)C)C)CO)O)O)O 1031.20 unknown https://doi.org/10.1016/0031-9422(92)83469-F
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
[(10R,11R,13R,14R,15S)-3,4,5,14,20,21,22-heptahydroxy-8,17-dioxo-11-(3,4,5-trihydroxybenzoyl)oxy-9,12,16-trioxatetracyclo[16.4.0.02,7.010,15]docosa-1(22),2,4,6,18,20-hexaen-13-yl]methyl 3,4,5-trihydroxybenzoate 101146656 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C3C(C(O2)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5C6=C(C(=C(C=C6C(=O)O3)O)O)O)O)O)O)O 786.60 unknown https://doi.org/10.1016/S0031-9422(00)90427-8

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