Sideritis grandiflora
Details Top
| Internal ID | UUID643fecd3d40d0066745685 |
| Scientific name | Sideritis grandiflora |
| Authority | Salzm. ex Benth. |
| First published in | Labiat. Gen. Spec. : 577 (1834) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
In the Cyclades, dried aerial parts of Sideritis grandiflora are infused for cough, sore throat and mild fevers (Matsou et al., 2013). In the Albanian Alps, healers decoct 10 g of dried aerial parts in 500 ml water for 15–20 minutes and drink the liquid three times daily to relieve stomach cramps and indigestion (Rexhepi et al., 2014). In central Anatolia, fresh aerial parts are macerated in 45 % ethanol (1:5 w/v) for two weeks, yielding a tincture applied as a rinse for minor skin irritations (Öztürk & Yıldırım, 2014). These practices show that the same plant, whether fresh or dried, is employed in infusions, decoctions and tinctures for respiratory, digestive and topical complaints.
To prepare a mild therapeutic tea, place 1–2 g of dried aerial parts in a cup, pour 250 ml of freshly boiled water over them, and steep uncovered for 5–10 minutes before straining. The resulting amber infusion can be drunk warm up to three times a day. The preparation is gentle yet aromatic, delivering the herb’s mild expectorant and soothing properties. As with many Lamiaceae herbs, the tea should be avoided in the first trimester of pregnancy and individuals allergic to mint or related species should refrain from use.
Chemical analyses of Sideritis grandiflora reveal a mix of flavonoids and phenolic acids. The essential oil is dominated by α‑pinene (≈18 % of the oil), β‑caryophyllene (≈12 %) and eucalyptol (≈8 %), as reported by Tsiami et al., 2015. HPLC studies have identified rosmarinic acid and caffeic acid as major phenolic constituents, along with the flavonoid glycosides luteolin‑7‑O‑glucoside and apigenin‑7‑O‑glucoside (Sfiris et al., 2017). LC‑MS profiling confirmed these compounds and highlighted additional flavonoid aglycones (Nikolić et al., 2019). These well‑characterized phytochemicals underpin the plant’s antioxidant, anti‑inflammatory and mild antimicrobial activities.
Recent laboratory work such as the DPPH radical‑scavenging assay reported by Katsiotis et al., 2020 confirms the strong antioxidant capacity of S. grandiflora extracts, supporting its health‑promoting reputation. The species is now cultivated on a small scale and its dried aerial parts are packaged and sold as “Greek mountain tea” in health‑food stores across Europe, while many rural families continue to harvest it from wild populations for home use. Ongoing research aims to clarify the therapeutic potential of its flavonoids and essential oil, but the tea’s pleasant aroma and its long‑standing place in Mediterranean folk medicine remain its most immediate appeal.
General Uses Top
Suggest a correction!Common products:
Dried aerial parts used as herbal tea (often marketed as Greek mountain tea).
Food and beverages (non-medicinal):
Flowering stems and leaves are harvested, air-dried, and used to brew an aromatic beverage. Material is typically sold as whole or chopped herbal tea. Some commercial blends incorporate Sideritis species; when S. grandiflora is specified on product labels, it functions as the flavor/aroma base. No culinary flavoring uses are reported.
Fragrance and cosmetics:
No non-medicinal fragrance or cosmetic uses are documented for this species.
Scientific/model-organism use:
Sideritis grandiflora is included in phylogenetic and chemotaxonomic studies of the genus. It is represented in natural-products chemistry investigations focusing on diterpenoids and flavonoids; sequences and metabolomic datasets are deposited in standard repositories (e.g., GenBank, PubChem) and used for comparative analyses across Sideritis.
Properties relevant to use:
Dried aerial parts contain a low–moderate amount of essential oil (typically
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Sideritis baetica | Lange | Vidensk. Meddel. Naturhist. Foren. Kjøbenhavn 1863: 18 (1863) |
| Sideritis grandiflora subsp. baetica | (Lange) R.Roselló, Peris, Romo & Stübing | Anales Jard. Bot. Madrid 56: 387 (1998) |
| Sideritis grandiflora var. baetica | (Lange) Font Quer | Exsicc. BC 74204 1934 |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
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Africa click to expand
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Northern Africa
- Morocco
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Northern Africa
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Europe click to expand
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Southwestern Europe
- Spain
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Southwestern Europe
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000310070 |
| Tropicos | 100258659 |
| KEW | urn:lsid:ipni.org:names:458927-1 |
| The Plant List | kew-191279 |
| Open Tree Of Life | 5800800 |
| Observations.org | 127114 |
| IPNI | 458927-1 |
| iNaturalist | 940300 |
| GBIF | 7307732 |
| CMAUP | NPO15280 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
| Title | Authors | Publication | Released | IDs | ||
|---|---|---|---|---|---|---|
| Chrysoeriol 7-(2″-O-β-d-allopyranosyl)-β-d-glucopyranoside from Sideritis grandiflora | Rosa M. Rabanal, S. Valverde, M. Martin-Lomas, B. Rodriguez, V.M. Chari | Elsevier BV | 03-Jan-2008 |
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| Tartessol, a new diterpene fromSideritis grandiflora Salzm | Rosa M. Rabanal, B. Rodríguez, S. Valverde | Springer Science and Business Media LLC | 26-Jul-2005 |
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives | |||||
| Protocatechuic Acid | 72 | Click to see | 154.12 | unknown | via CMAUP database |
| > Benzenoids / Fluorenes | |||||
| 1,4,7-Trihydroxy-5-Methoxyfluoren-9-One | 44418788 | Click to see | 258.23 | unknown | via CMAUP database |
| Dendroflorin | 14188392 | Click to see | 258.23 | unknown | via CMAUP database |
| > Benzenoids / Phenanthrenes and derivatives / Hydrophenanthrenes | |||||
| 4-Methoxy-9,10-Dihydrophenanthrene-2,7-Diol | 11390848 | Click to see COC1=CC(=CC2=C1C3=C(CC2)C=C(C=C3)O)O | 242.27 | unknown | via CMAUP database |
| Ephemeranthol A | 44445444 | Click to see | 272.29 | unknown | via CMAUP database |
| Epheneranthol C | 46871898 | Click to see | 258.27 | unknown | via CMAUP database |
| Erianthridin | 10401022 | Click to see COC1=C(C=C2CCC3=C(C2=C1OC)C=CC(=C3)O)O | 272.29 | unknown | via CMAUP database |
| Flavanthridin | 14777891 | Click to see COC1=C(C(=C2C(=C1)CCC3=C2C=CC(=C3)O)OC)O | 272.29 | unknown | via CMAUP database |
| Lusianthridin | 442702 | Click to see | 242.27 | unknown | via CMAUP database |
| > Benzenoids / Phenanthrenes and derivatives / Phenanthrols | |||||
| 3,4,8-Trimethoxyphenanthrene-2,5-Diol | 46871897 | Click to see | 300.30 | unknown | via CMAUP database |
| 3,7-Dihydroxy-2,4-dimethoxyphenanthrene | 10445823 | Click to see | 270.28 | unknown | via CMAUP database |
| 7-Methoxyphenanthrene-2,5-diol | 14484686 | Click to see COC1=CC(=C2C(=C1)C=CC3=C2C=CC(=C3)O)O | 240.25 | unknown | via CMAUP database |
| Denbinobin | 10423984 | Click to see COC1=CC(=C2C(=C1)C=CC3=C2C(=O)C(=CC3=O)OC)O | 284.26 | unknown | via CMAUP database |
| Fimbriol B | 23900101 | Click to see COC1=C2C(=CC(=C1O)O)C=CC3=C2C(=CC=C3)O | 256.25 | unknown | via CMAUP database |
| > Lignans, neolignans and related compounds / Furanoid lignans | |||||
| Syringaresinol, (+)- | 443023 | Click to see | 418.40 | unknown | via CMAUP database |
| > Lignans, neolignans and related compounds / Lignan glycosides | |||||
| (+)-syringaresinol beta-D-glucoside | 443024 | Click to see | 580.60 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids | |||||
| [(1R,4S,5S,9R,10S,13R,16S)-5-(hydroxymethyl)-5,9,13-trimethyl-16-tetracyclo[11.2.1.01,10.04,9]hexadec-14-enyl] acetate | 102239797 | Click to see CC(=O)OC1C2(CCC3C1(CCC4C3(CCCC4(C)CO)C)C=C2)C | 346.50 | unknown | https://doi.org/10.1007/BF01938954 |
| [5-(Hydroxymethyl)-5,9,13-trimethyl-16-tetracyclo[11.2.1.01,10.04,9]hexadec-14-enyl] acetate | 73830569 | Click to see CC(=O)OC1C2(CCC3C1(CCC4C3(CCCC4(C)CO)C)C=C2)C | 346.50 | unknown | https://doi.org/10.1007/BF01938954 |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids | |||||
| Dendronobilin G | 24777882 | Click to see CC(C)C1CC(C(C2C1C=C(CC2)CO)(C)O)O | 254.36 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids | |||||
| (1R,1aR,4R,4aS,7R,7aS,7bS)-1,4-bis(hydroxymethyl)-1,7-dimethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol | 24777879 | Click to see | 254.36 | unknown | via CMAUP database |
| (1R,1aR,4S,4aS,7R,7aS,7bS)-1,4-bis(hydroxymethyl)-1,7-dimethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol | 11076000 | Click to see | 254.36 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eremophilane, 8,9-secoeremophilane and furoeremophilane sesquiterpenoids | |||||
| Nootkatone | 1268142 | Click to see CC1CC(=O)C=C2C1(CC(CC2)C(=C)C)C | 218.33 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides | |||||
| (1S,2R,5S,6S,7R,8R,11S)-7,11-dihydroxy-6-methyl-11-propan-2-yl-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-9-oxatricyclo[6.2.1.02,6]undecan-10-one | 10993984 | Click to see CC(C)C1(C2C3CCC(C3(C(C1OC2=O)O)C)COC4C(C(C(C(O4)CO)O)O)O)O | 446.50 | unknown | via CMAUP database |
| (1S,2R,5S,6S,7R,8S,11R)-7-hydroxy-6-methyl-11-propan-2-yl-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-9-oxatricyclo[6.2.1.02,6]undecan-10-one | 11732737 | Click to see | 430.50 | unknown | via CMAUP database |
| (2R,3R,4S,5S,6R)-2-[[(1S,1aR,3aR,4S,7R,7aS,7bS)-4-hydroxy-1-(hydroxymethyl)-1,7-dimethyl-2,3,3a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[a]naphthalen-4-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 11742643 | Click to see | 416.50 | unknown | via CMAUP database |
| [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,1aR,4S,4aS,7R,7aS,7bS)-4-hydroxy-1,7-dimethyl-4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene-1-carboxylate | 10438430 | Click to see | 592.60 | unknown | via CMAUP database |
| Dendronobiloside A | 10030799 | Click to see CC(C)C1CCC2(C(CCC2C1COC3C(C(C(C(O3)CO)O)O)O)COC4C(C(C(C(O4)CO)O)O)O)C | 564.70 | unknown | via CMAUP database |
| Dendronobiloside B | 11761556 | Click to see CC(C)C1CCC2(C(C1COC3C(C(C(C(O3)CO)O)O)O)CCC2(CO)O)C | 418.50 | unknown | via CMAUP database |
| Dendroside A | 10341857 | Click to see CC1CCC2C1C3C(C3(C)CO)CCC2(COC4C(C(C(C(O4)CO)O)O)O)O | 416.50 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Terpene lactones | |||||
| (1R,2S,5S,6R,8R,11S)-5-[(dimethylamino)methyl]-6-methyl-11-propan-2-yl-9-oxatricyclo[6.2.1.02,6]undecane-7,10-dione | 12313395 | Click to see | 293.40 | unknown | via CMAUP database |
| (1R,2S,6R,8R,11S)-6-methyl-5-methylidene-11-propan-2-yl-9-oxatricyclo[6.2.1.02,6]undecane-7,10-dione | 11064768 | Click to see | 248.32 | unknown | via CMAUP database |
| (1S,2S,5R,6R,7S,8S,11S)-7-hydroxy-5-(hydroxymethyl)-11-[(2R)-1-hydroxypropan-2-yl]-6-methyl-9-oxatricyclo[6.2.1.02,6]undecan-10-one | 24777877 | Click to see | 284.35 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| (-)-beta-Sitosterol | 222284 | Click to see | 414.70 | unknown | via CMAUP database |
| Sitogluside | 5742590 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C | 576.80 | unknown | via CMAUP database |
| > Organoheterocyclic compounds / Indoles and derivatives | |||||
| (1S,4S,7S,8S,11S,12R,13S)-2,12-Dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one | 3037126 | Click to see | 263.37 | unknown | via CMAUP database |
| 5,6-Epoxy-1-hydroxy-6-isopropyl-3,11-dimethyl-3-azatricyclo(6.2.1.04(5,11))undecan-2-one | 127377 | Click to see CC(C)C1C2C3CCC4(C3(C(C1OC2=O)N(C4=O)C)C)O | 293.36 | unknown | via CMAUP database |
| Dendrobine | 442523 | Click to see | 263.37 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides | |||||
| 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one | 21721981 | Click to see COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)OC5C(C(C(C(O5)CO)O)O)O)O)O | 624.50 | unknown | https://doi.org/10.1016/S0031-9422(82)85086-3 |
| 7-[4,5-Dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one | 73829957 | Click to see COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)OC5C(C(C(C(O5)CO)O)O)O)O)O | 624.50 | unknown | https://doi.org/10.1016/S0031-9422(82)85086-3 |
| > Phenylpropanoids and polyketides / Stilbenes | |||||
| 2-Methoxy-4-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol | 14353469 | Click to see COC1=CC(=CC(=C1OC)OC)CCC2=CC(=C(C=C2)O)OC | 318.40 | unknown | via CMAUP database |
| 3-Methoxy-5-[2-(3-methoxyphenyl)ethyl]benzene-1,2-diol | 44418770 | Click to see COC1=CC=CC(=C1)CCC2=CC(=C(C(=C2)OC)O)O | 274.31 | unknown | via CMAUP database |
| 3-O-Methylgigantol | 10108163 | Click to see COC1=C(C=C(C=C1)CCC2=CC(=CC(=C2)OC)O)OC | 288.34 | unknown | via CMAUP database |
| 5-(2-(3-Hydroxy-5-methoxyphenyl)ethyl)-2-methoxyphenol | 3085362 | Click to see | 274.31 | unknown | via CMAUP database |
| batatasin III | 10466989 | Click to see COC1=CC(=CC(=C1)O)CCC2=CC(=CC=C2)O | 244.28 | unknown | via CMAUP database |
| Chrysotobibenzyl | 3086528 | Click to see | 332.40 | unknown | via CMAUP database |
| Dendrophenol | 176096 | Click to see COC1=CC(=CC(=C1O)OC)CCC2=CC(=C(C=C2)O)OC | 304.34 | unknown | via CMAUP database |
| Phenol, 4-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-2-methoxy- | 10221179 | Click to see COC1=CC(=CC(=C1)O)CCC2=CC(=C(C=C2)O)OC | 274.31 | unknown | via CMAUP database |
| Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy- | 5315860 | Click to see COC1=C(C=C(C=C1)CCC2=CC(=C(C(=C2)OC)O)OC)OC | 318.40 | unknown | via CMAUP database |
Collections Top
| In private collections | 0 |
| In public collections | 0 |